Lam YM et al. |
Histone deacetylase inhibitors induce leukemia gene expression in cord blood hematopoietic stem cells expanded ex vivo. |
2017 |
Int. J. Hematol. |
pmid:27531147
|
Scholpa NE et al. |
Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer. |
2016 |
Chem. Biol. Interact. |
pmid:27543423
|
Vargas-López V et al. |
Histone deacetylase inhibition abolishes stress-induced spatial memory impairment. |
2016 |
Neurobiol Learn Mem |
pmid:27544851
|
Zhang XF et al. |
Trichostatin A Enhances the Apoptotic Potential of Palladium Nanoparticles in Human Cervical Cancer Cells. |
2016 |
Int J Mol Sci |
pmid:27548148
|
Sugiyama KI et al. |
Epigenetic mutagen as histone modulator can be detected by yeast flocculation. |
2016 |
Mutagenesis |
pmid:27549112
|
DÃaz-Núñez M et al. |
Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity. |
2016 |
BMC Cancer |
pmid:27549189
|
Duffy S et al. |
Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer. |
2016 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:27551064
|
Kotantaki P and Mosialos G |
The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines. |
2016 |
Cell Biochem. Funct. |
pmid:27570065
|
Ho TT et al. |
Transient resistance to DNA damaging agents is associated with expression of microRNAs-135b and -196b in human leukemia cell lines. |
2016 |
Int J Biochem Mol Biol |
pmid:27570640
|
Park IH et al. |
Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium. |
2016 |
PLoS ONE |
pmid:27571418
|
Tiper IV and Webb TJ |
Histone deacetylase inhibitors enhance CD1d-dependent NKT cell responses to lymphoma. |
2016 |
Cancer Immunol. Immunother. |
pmid:27614429
|
Desjardins D et al. |
Histone Deacetylase Inhibition Restores Retinal Pigment Epithelium Function in Hyperglycemia. |
2016 |
PLoS ONE |
pmid:27617745
|
Zhang Q et al. |
Trichostatin A protects against intestinal injury in rats with acute liver failure. |
2016 |
J. Surg. Res. |
pmid:27620992
|
Chen W et al. |
MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. |
2016 |
Biochim. Biophys. Acta |
pmid:27638301
|
Xu Q et al. |
Changes in cardiac Nav1.5 expression, function, and acetylation by pan-histone deacetylase inhibitors. |
2016 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:27638876
|
Tao W et al. |
Histone deacetylase inhibitor-induced emergence of synaptic δ-opioid receptors and behavioral antinociception in persistent neuropathic pain. |
2016 |
Neuroscience |
pmid:27646288
|
Sobue S et al. |
Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27687545
|
Rong X et al. |
Effects of histone acetylation on superoxide dismutase 1 gene expression in the pathogenesis of senile cataract. |
2016 |
Sci Rep |
pmid:27703255
|
Ladrech S et al. |
High mobility group box 1 (HMGB1): dual functions in the cochlear auditory neurons in response to stress? |
2017 |
Histochem. Cell Biol. |
pmid:27704212
|
Hrgovic I et al. |
The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. |
2016 |
BMC Cancer |
pmid:27716272
|
Morinobu A et al. |
Expression and Functions of Immediate Early Response Gene X-1 (IEX-1) in Rheumatoid Arthritis Synovial Fibroblasts. |
2016 |
PLoS ONE |
pmid:27736946
|
Wisnieski F et al. |
BMP8B Is a Tumor Suppressor Gene Regulated by Histone Acetylation in Gastric Cancer. |
2017 |
J. Cell. Biochem. |
pmid:27748538
|
Nadanaka S et al. |
Histone deacetylase-mediated regulation of chondroitin 4-O-sulfotransferase-1 (Chst11) gene expression by Wnt/β-catenin signaling. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27751852
|
Unruhe-Knauf B and Knauer SK |
Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. |
2017 |
Methods Mol. Biol. |
pmid:27761812
|
Buchou T et al. |
Purification and Analysis of Male Germ Cells from Adult Mouse Testis. |
2017 |
Methods Mol. Biol. |
pmid:27761820
|
Pinz S and Rascle A |
Assessing HDAC Function in the Regulation of Signal Transducer and Activator of Transcription 5 (STAT5) Activity Using Chromatin Immunoprecipitation (ChIP). |
2017 |
Methods Mol. Biol. |
pmid:27761827
|
Staberg M et al. |
Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine. |
2017 |
Cell Oncol (Dordr) |
pmid:27766591
|
Bauer I et al. |
A Class 1 Histone Deacetylase with Potential as an Antifungal Target. |
2016 |
MBio |
pmid:27803184
|
Zapletal O et al. |
Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models. |
2017 |
Arch. Toxicol. |
pmid:27830268
|
Tombolan L et al. |
Global DNA methylation profiling uncovers distinct methylation patterns of protocadherin alpha4 in metastatic and non-metastatic rhabdomyosarcoma. |
2016 |
BMC Cancer |
pmid:27842508
|
Choi SA et al. |
A novel histone deacetylase inhibitor, CKD5, has potent anti-cancer effects in glioblastoma. |
2017 |
Oncotarget |
pmid:27852054
|
Kim HR et al. |
Aberrant Expression of TIMP-2 and PBEF Genes in the Placentae of Cloned Mice Due to Epigenetic Reprogramming Error. |
2016 |
PLoS ONE |
pmid:27855185
|
Huynh NC et al. |
Histone deacetylase inhibition enhances in-vivo bone regeneration induced by human periodontal ligament cells. |
2017 |
Bone |
pmid:27871909
|
Deng Z et al. |
Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation. |
2016 |
Int. J. Biol. Sci. |
pmid:27877082
|
Jia L et al. |
Trichostatin A increases radiosensitization of tongue squamous cell carcinoma via miR‑375. |
2017 |
Oncol. Rep. |
pmid:27878285
|
Bricambert J et al. |
Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function. |
2016 |
Mol Metab |
pmid:27900262
|
Cipriano M et al. |
The role of epigenetic modifiers in extended cultures of functional hepatocyte-like cells derived from human neonatal mesenchymal stem cells. |
2017 |
Arch. Toxicol. |
pmid:27909741
|
Takamatsu G et al. |
Tescalcin is a potential target of class I histone deacetylase inhibitors in neurons. |
2017 |
Biochem. Biophys. Res. Commun. |
pmid:27939885
|
Mengel A et al. |
Nitric Oxide Modulates Histone Acetylation at Stress Genes by Inhibition of Histone Deacetylases. |
2017 |
Plant Physiol. |
pmid:27980017
|
Aquea F et al. |
Chemical inhibition of the histone acetyltransferase activity in Arabidopsis thaliana. |
2017 |
Biochem. Biophys. Res. Commun. |
pmid:27993678
|
Choiniere J et al. |
Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins. |
2017 |
Mol. Pharmacol. |
pmid:28003426
|
Duan H et al. |
The effect of histone deacetylase inhibition on the expression of P-glycoprotein in human placental trophoblast cell lines. |
2017 |
Placenta |
pmid:28012453
|
Mazzio EA and Soliman KF |
HTP Nutraceutical Screening for Histone Deacetylase Inhibitors and Effects of HDACis on Tumor-suppressing miRNAs by Trichostatin A and Grapeseed (Vitis vinifera) in HeLa cells. |
2017 |
Cancer Genomics Proteomics |
pmid:28031235
|
Alqinyah M et al. |
Regulator of G Protein Signaling 10 (Rgs10) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity. |
2017 |
Mol. Pharmacol. |
pmid:28031332
|
Campo VA |
Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression. |
2017 |
Int J Parasitol Drugs Drug Resist |
pmid:28038431
|
Pachano T et al. |
Epigenetics regulates transcription and pathogenesis in the parasite Trichomonas vaginalis. |
2017 |
Cell. Microbiol. |
pmid:28054438
|
Hichino A et al. |
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. |
2017 |
J. Biol. Chem. |
pmid:28057758
|
Chen L et al. |
PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer. |
2017 |
Oncotarget |
pmid:28060760
|
Cao Z et al. |
TSA and BIX-01294 Induced Normal DNA and Histone Methylation and Increased Protein Expression in Porcine Somatic Cell Nuclear Transfer Embryos. |
2017 |
PLoS ONE |
pmid:28114389
|
Wang XJ et al. |
Opposing Roles of Acetylation and Phosphorylation in LIFR-Dependent Self-Renewal Growth Signaling in Mouse Embryonic Stem Cells. |
2017 |
Cell Rep |
pmid:28122243
|
Vanneste M et al. |
Hyaluronate synthase-2 overexpression alters estrogen dependence and induces histone deacetylase inhibitor-like effects on ER-driven genes in MCF7 breast tumor cells. |
2017 |
Mol. Cell. Endocrinol. |
pmid:28137613
|
Gilardini Montani MS et al. |
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells. |
2017 |
Cell Oncol (Dordr) |
pmid:28160167
|
Trifunović D et al. |
HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo. |
2016 |
Hum. Mol. Genet. |
pmid:28172811
|
Wu Y et al. |
Suppression of Excessive Histone Deacetylases Activity in Diabetic Hearts Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondria Apoptosis Pathway. |
2017 |
J Diabetes Res |
pmid:28191472
|
Li LF et al. |
Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway. |
2017 |
PLoS ONE |
pmid:28234968
|
Lin S et al. |
Silencing of ATP4B of ATPase H/K Transporting Beta Subunit by Intragenic Epigenetic Alteration in Human Gastric Cancer Cells. |
2017 |
Oncol. Res. |
pmid:28281974
|
Ikeda K et al. |
In vitro drug testing based on contractile activity of C2C12 cells in an epigenetic drug model. |
2017 |
Sci Rep |
pmid:28300163
|
Chang YW and Singh KP |
Long-term exposure to estrogen enhances chemotherapeutic efficacy potentially through epigenetic mechanism in human breast cancer cells. |
2017 |
PLoS ONE |
pmid:28323900
|
Kim YH and Lee JK |
Histone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression. |
2017 |
Cell. Immunol. |
pmid:28341057
|
Xie C et al. |
In vitro analysis of factors influencing expression as potential determinants of interindividual variation. |
2017 |
Pharmacol Res Perspect |
pmid:28357125
|
Shao G et al. |
Inactivation of EGFR/AKT signaling enhances TSA-induced ovarian cancer cell differentiation. |
2017 |
Oncol. Rep. |
pmid:28393191
|
Anderson L et al. |
Histone deacetylase inhibition modulates histone acetylation at gene promoter regions and affects genome-wide gene transcription in Schistosoma mansoni. |
2017 |
PLoS Negl Trop Dis |
pmid:28406899
|
Lin W et al. |
Klotho restoration via acetylation of Peroxisome Proliferation-Activated Receptor γ reduces the progression of chronic kidney disease. |
2017 |
Kidney Int. |
pmid:28416226
|
Golfier S et al. |
High-throughput cell mechanical phenotyping for label-free titration assays of cytoskeletal modifications. |
2017 |
Cytoskeleton (Hoboken) |
pmid:28445605
|
Acun T et al. |
HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer. |
2017 |
OMICS |
pmid:28481734
|
Wei W et al. |
Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription. |
2017 |
Cell Res. |
pmid:28497810
|
Kudo K et al. |
Biosynthetic Origin of the Hydroxamic Acid Moiety of Trichostatin A: Identification of Unprecedented Enzymatic Machinery Involved in Hydroxylamine Transfer. |
2017 |
J. Am. Chem. Soc. |
pmid:28497964
|
Anantharaju PG et al. |
Naturally occurring benzoic acid derivatives retard cancer cell growth by inhibiting histone deacetylases (HDAC). |
2017 |
Cancer Biol. Ther. |
pmid:28506198
|
Duan HY et al. |
Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line. |
2017 |
Chin. Med. J. |
pmid:28524836
|
Pandey P et al. |
Dynamics of post-translationally modified histones during barley pollen embryogenesis in the presence or absence of the epi-drug trichostatin A. |
2017 |
Plant Reprod |
pmid:28526911
|
Ilicic M et al. |
Modulation of Progesterone Receptor Isoform Expression in Pregnant Human Myometrium. |
2017 |
Biomed Res Int |
pmid:28540297
|
Yeakley JM et al. |
A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling. |
2017 |
PLoS ONE |
pmid:28542535
|
Gurgul A et al. |
The effect of histone deacetylase inhibitor trichostatin A on porcine mesenchymal stem cell transcriptome. |
2017 |
Biochimie |
pmid:28552396
|
Hou X et al. |
HDAC inhibitor TSA ameliorates mechanical hypersensitivity and potentiates analgesic effect of morphine in a rat model of bone cancer pain by restoring μ-opioid receptor in spinal cord. |
2017 |
Brain Res. |
pmid:28559159
|
Opiela J et al. |
In vitro development and cytological quality of inter-species (porcine→bovine) cloned embryos are affected by trichostatin A-dependent epigenomic modulation of adult mesenchymal stem cells. |
2017 |
Theriogenology |
pmid:28583605
|
Bouzelfen A et al. |
Heterogeneous epigenetic regulation of HACE1 in Burkitt- Lymphoma-derived cells. |
2017 |
Leuk. Res. |
pmid:28651105
|
Jih G et al. |
Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. |
2017 |
Nature |
pmid:28682306
|
Pérez-Garrastachu M et al. |
Nucleoporins redistribute inside the nucleus after cell cycle arrest induced by histone deacetylases inhibition. |
2017 |
Nucleus |
pmid:28696859
|
Wang SC et al. |
Trichostatin A induces bladder cancer cell death via intrinsic apoptosis at the early phase and Sp1‑survivin downregulation at the late phase of treatment. |
2017 |
Oncol. Rep. |
pmid:28713892
|
Jayaraman A et al. |
The epigenetic drug Trichostatin A ameliorates experimental autoimmune encephalomyelitis via T cell tolerance induction and impaired influx of T cells into the spinal cord. |
2017 |
Neurobiol. Dis. |
pmid:28736194
|
Green AL et al. |
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1. |
2017 |
Neuropharmacology |
pmid:28743636
|
Jorstad NL et al. |
Stimulation of functional neuronal regeneration from Müller glia in adult mice. |
2017 |
Nature |
pmid:28746305
|
Jiang F et al. |
Trichostatin A increases embryo and green plant regeneration in wheat. |
2017 |
Plant Cell Rep. |
pmid:28752355
|
Ngwa CJ et al. |
Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite . |
2017 |
Front Cell Infect Microbiol |
pmid:28791254
|
Simões-Pires CA et al. |
Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS. |
2017 |
J Vis Exp |
pmid:28829415
|
Tao LL et al. |
TSA increases C/EBP‑α expression by increasing its lysine acetylation in hepatic stellate cells. |
2017 |
Mol Med Rep |
pmid:28849174
|
Guo Y et al. |
Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway. |
2017 |
Int. J. Mol. Med. |
pmid:28849190
|
Fujikawa J et al. |
Kruppel-like factor 4 regulates matrix metalloproteinase and aggrecanase gene expression in chondrocytes. |
2017 |
Cell Tissue Res. |
pmid:28856432
|
Zheng C et al. |
Histone Deacetylase Inhibitors Relax Mouse Aorta Partly through Their Inhibitory Action on L-Type Ca Channels. |
2017 |
J. Pharmacol. Exp. Ther. |
pmid:28860353
|
Shin S et al. |
Trichostatin A Sensitizes Hepatocellular Carcinoma Cells to Enhanced NK Cell-mediated Killing by Regulating Immune-related Genes. |
|
Cancer Genomics Proteomics |
pmid:28871002
|
Buishand FO et al. |
Trichostatin A preferentially reverses the upregulation of gene-expression levels induced by gain of chromosome 7 in colorectal cancer cell lines. |
2018 |
Genes Chromosomes Cancer |
pmid:28940826
|
Zhang C et al. |
An epigenetic bioactive composite scaffold with well-aligned nanofibers for functional tendon tissue engineering. |
2018 |
Acta Biomater |
pmid:28963019
|
Wei ZQ et al. |
Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation. |
2017 |
World J. Gastroenterol. |
pmid:28974891
|
Nagaraja SS et al. |
Effect of Trichostatin A on radiation induced epithelial-mesenchymal transition in A549Â cells. |
2017 |
Biochem. Biophys. Res. Commun. |
pmid:28993195
|
Song Y et al. |
Trichostatin A and 5-Aza-2'-Deoxycytidine influence the expression of cold-induced genes in Arabidopsis. |
2017 |
Plant Signal Behav |
pmid:29027833
|
Androutsopoulos VP and Spandidos DA |
Antiproliferative effects of TSA, PXD‑101 and MS‑275 in A2780 and MCF7 cells: Acetylated histone H4 and acetylated tubulin as markers for HDACi potency and selectivity. |
2017 |
Oncol. Rep. |
pmid:29039546
|
Zhang Z et al. |
Role of histone acetylation in activation of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway by manganese chloride. |
2017 |
Toxicol. Appl. Pharmacol. |
pmid:29054681
|
Hartl M et al. |
Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in . |
2017 |
Mol. Syst. Biol. |
pmid:29061669
|
Xing M et al. |
Histone deacetylase inhibitor stimulates E2 and P4 secretion in sika deer ovarian granulosa cells at a moderate dose. |
2018 |
Cell Biol. Int. |
pmid:29064603
|
Ma T et al. |
Suppression of BMP-7 by histone deacetylase 2 promoted apoptosis of renal tubular epithelial cells in acute kidney injury. |
2017 |
Cell Death Dis |
pmid:29072686
|