trichostatin A

Trichostatin is a lipid of Polyketides (PK) class. Trichostatin is associated with abnormalities such as Dentatorubral-Pallidoluysian Atrophy, PARAGANGLIOMAS 3, abnormal fragmented structure, Disintegration (morphologic abnormality) and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Acetylation, Cell Differentiation process, histone modification, Gene Silencing and Transcriptional Activation. Trichostatin often locates in CD41a, Hematopoietic System, Chromatin Structure, Blood and Endothelium. The associated genes with Trichostatin are SPI1 gene, CELL Gene, Chromatin, CXCR4 gene and DNMT1 gene. The related lipids are Butyrates, Promega, butyrate, Lipopolysaccharides and Steroids. The related experimental models are Knock-out, Mouse Model, Xenograft Model and Cancer Model.

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Introduction

To understand associated biological information of trichostatin A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with trichostatin A?

trichostatin A is suspected in Infection, Morphologically altered structure, Ureteral obstruction, Photosensitization, Atherosclerosis, Hypertrophic Cardiomyopathy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with trichostatin A

MeSH term MeSH ID Detail
Neoplasm Micrometastasis D061206 1 associated lipids
Cystadenoma, Serous D018293 1 associated lipids
Supratentorial Neoplasms D015173 1 associated lipids
von Hippel-Lindau Disease D006623 1 associated lipids
Intervertebral Disc Degeneration D055959 1 associated lipids
Hypesthesia D006987 1 associated lipids
Cystadenocarcinoma, Mucinous D018282 1 associated lipids
Myopathy, Central Core D020512 1 associated lipids
Roseolovirus Infections D019349 1 associated lipids
Thyroid Hormone Resistance Syndrome D018382 1 associated lipids
Chromosome Inversion D007446 1 associated lipids
Rhabdomyosarcoma, Embryonal D018233 1 associated lipids
Gestational Trophoblastic Disease D031901 1 associated lipids
Carcinoma, Papillary, Follicular D018265 1 associated lipids
Rhabdoid Tumor D018335 1 associated lipids
Visceral Pain D059265 1 associated lipids
Lupus Vulgaris D008177 1 associated lipids
Rubinstein-Taybi Syndrome D012415 1 associated lipids
Goldenhar Syndrome D006053 1 associated lipids
Classical Lissencephalies and Subcortical Band Heterotopias D054221 1 associated lipids
Adenomyosis D062788 1 associated lipids
Capsule Opacification D058442 1 associated lipids
Adenocarcinoma, Papillary D000231 2 associated lipids
Inflammatory Breast Neoplasms D058922 2 associated lipids
Ganglioneuroma D005729 2 associated lipids
Cystadenocarcinoma, Serous D018284 2 associated lipids
Fibromatosis, Aggressive D018222 2 associated lipids
Rhabdomyosarcoma, Alveolar D018232 2 associated lipids
Small Cell Lung Carcinoma D055752 2 associated lipids
Bone Marrow Neoplasms D019046 2 associated lipids
Hypereosinophilic Syndrome D017681 3 associated lipids
Lymphoma, Follicular D008224 3 associated lipids
Lymphoma, Large-Cell, Anaplastic D017728 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Progeria D011371 3 associated lipids
Mastocytoma D034801 3 associated lipids
Uveal Neoplasms D014604 3 associated lipids
Leukemia, Promyelocytic, Acute D015473 3 associated lipids
Conjunctival Neoplasms D003230 3 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Opioid-Related Disorders D009293 5 associated lipids
Osteomalacia D010018 5 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Myeloproliferative Disorders D009196 5 associated lipids
Primary Myelofibrosis D055728 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with trichostatin A

Lipid pathways are not clear in current pathway databases. We organized associated pathways with trichostatin A through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with trichostatin A?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with trichostatin A?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with trichostatin A?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with trichostatin A?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with trichostatin A?

Mouse Model

Mouse Model are used in the study 'Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer.' (Majid S et al., 2010), Mouse Model are used in the study 'Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.' (Fang MZ et al., 2005) and Mouse Model are used in the study 'Histone deacetylase 3 mediates allergic skin inflammation by regulating expression of MCP1 protein.' (Kim Y et al., 2012).

Xenograft Model

Xenograft Model are used in the study 'Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.' (Landreville S et al., 2012), Xenograft Model are used in the study 'Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.' (Moiseeva EP et al., 2007) and Xenograft Model are used in the study 'Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.' (Touma SE et al., 2005).

Cancer Model

Cancer Model are used in the study 'Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice.' (Sanderson L et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with trichostatin A

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Per page 10 20 50 100 | Total 3126
Authors Title Published Journal PubMed Link
Ellis JK et al. Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes. 2010 J. Proteome Res. pmid:19894772
Bhuiyan MM et al. Production of Sei whale (Balaenoptera borealis) cloned embryos by inter- and intra-species somatic cell nuclear transfer. 2010 J. Reprod. Dev. pmid:19893277
Dong G et al. Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells. 2010 Am. J. Physiol. Renal Physiol. pmid:19889954
Ma X et al. Identification of LIV1, a putative zinc transporter gene responsible for HDACi-induced apoptosis, using a functional gene screen approach. 2009 Mol. Cancer Ther. pmid:19887557
Ninios YP et al. Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells. 2010 Apoptosis pmid:19882353
Krishnan M et al. HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability. 2010 Oncogene pmid:19881542
Kusakabe M et al. Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists. 2009 Biochem. Biophys. Res. Commun. pmid:19878646
Li X et al. Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos. 2009 Blood pmid:19864643
Meng CF et al. Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells. 2010 Cancer Invest. pmid:19857042
Ai J et al. HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer. 2009 Mol. Endocrinol. pmid:19855091
Di Renzo F et al. VPA-related axial skeletal defects and apoptosis: a proposed event cascade. 2010 Reprod. Toxicol. pmid:19850124
Wang Y et al. HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. 2009 Neurosci. Lett. pmid:19835929
Röhrs S et al. Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. 2009 Mol. Cancer pmid:19835597
Puca R et al. HIPK2 modulates p53 activity towards pro-apoptotic transcription. 2009 Mol. Cancer pmid:19828042
Li C et al. Induction of myelogenous leukemia cells with histone deacetylase inhibitors through down-regulating the Daxx protein expression. 2009 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:19821084
Hara D et al. Persistent BDNF exon I-IX mRNA expression following the withdrawal of neuronal activity in neurons. 2009 Biochem. Biophys. Res. Commun. pmid:19818730
Gray SG et al. Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications. 2009 Eur. J. Cancer pmid:19818596
Hui KF and Chiang AK Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and mediates enhanced cell death. 2010 Int. J. Cancer pmid:19816947
Lee JH et al. Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. 2009 Mol. Cancer Res. pmid:19808903
Li X et al. Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. 2010 Br. J. Haematol. pmid:19807731
Gibbs A et al. Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19805354
Sasaki K et al. Real-time imaging of histone H4 hyperacetylation in living cells. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19805290
Liberatore RA et al. NF-kappaB activity is constitutively elevated in c-Abl null fibroblasts. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19805123
Wu P et al. Ubiquitin B: an essential mediator of trichostatin A-induced tumor-selective killing in human cancer cells. 2010 Cell Death Differ. pmid:19798105
Sponziello M et al. Regulation of sodium/iodide symporter and lactoperoxidase expression in four human breast cancer cell lines. 2010 J. Endocrinol. Invest. pmid:19794300
Federman N et al. Histone acetylation is recruited in consolidation as a molecular feature of stronger memories. 2009 Learn. Mem. pmid:19794185
Iljin K et al. High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth. 2009 Clin. Cancer Res. pmid:19789329
Meng CF et al. Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. 2009 Oncol. Rep. pmid:19787243
Law AY and Wong CK Stanniocalcin-2 is a HIF-1 target gene that promotes cell proliferation in hypoxia. 2010 Exp. Cell Res. pmid:19786016
Chen CZ et al. The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well. 2009 Br. J. Pharmacol. pmid:19785660
Higashiyama R et al. Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis. 2010 Mod Rheumatol pmid:19784544
Ninios YP et al. Differential sensitivity of human leukemic cell lines to the histone deacetylase inhibitor, trichostatin A. 2010 Leuk. Res. pmid:19782399
Beebe LF et al. Cytochalasin B and trichostatin a treatment postactivation improves in vitro development of porcine somatic cell nuclear transfer embryos. 2009 Cloning Stem Cells pmid:19780698
Fan J et al. Expression and function of CD9 in melanoma cells. 2010 Mol. Carcinog. pmid:19777564
Obier N and Müller AM Chromatin flow cytometry identifies changes in epigenetic cell states. 2010 Cells Tissues Organs (Print) pmid:19776550
Diplas AI et al. Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. 2009 Nucleic Acids Res. pmid:19767614
Kim HN et al. Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. 2009 Eur. J. Pharmacol. pmid:19766111
Cervera RP et al. Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryos. 2009 Theriogenology pmid:19765811
Vire B et al. Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions. 2009 PLoS ONE pmid:19759901
Chiou SK and Hoa N Up-regulation of GADD45alpha expression by NSAIDs leads to apoptotic and necrotic colon cancer cell deaths. 2009 Apoptosis pmid:19757064
Hirata H et al. Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. 2009 Clin. Cancer Res. pmid:19755393
Wang X et al. Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents. 2009 Cancer Res. pmid:19752087
Sterthaus O et al. Evaluation of in vitro cultured rat oocytes, from different strains, by spindle morphology and maturation-promoting-factor activity combined with nuclear-transfer experiments. 2009 Cloning Stem Cells pmid:19751114
Lugrin J et al. Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation. 2009 Biochim. Biophys. Acta pmid:19747950
Dandrea M et al. MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. 2009 Nucleic Acids Res. pmid:19745053
Dombrowsky H et al. Conserved responses to trichostatin A in rodent lungs exposed to endotoxin or stretch. 2009 Pulm Pharmacol Ther pmid:19744573
Yoshizawa Y et al. Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection. 2010 Mol. Reprod. Dev. pmid:19743475
Meng CF et al. [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. 2009 Zhonghua Wei Chang Wai Ke Za Zhi pmid:19742343
Bennett KL et al. AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. 2009 PLoS ONE pmid:19742317
Kashiwagi Y et al. Trichostatin A-induced TGF-beta type II receptor expression in retinoblastoma cell lines. 2010 Invest. Ophthalmol. Vis. Sci. pmid:19737884
Ong DC et al. LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer. 2009 Oncogene pmid:19734946
Mousa SA et al. Stress resistant human embryonic stem cells as a potential source for the identification of novel cancer stem cell markers. 2010 Cancer Lett. pmid:19733430
Kee HJ and Kook H Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy. 2009 J. Mol. Cell. Cardiol. pmid:19729022
Her S et al. Trichostatin A stimulates steroid 5alpha-reductase gene expression in rat C6 glioma cells via a mechanism involving Sp1 and Sp3 transcription factors. 2010 J. Mol. Neurosci. pmid:19728174
Alao JP et al. Inhibition of type I histone deacetylase increases resistance of checkpoint-deficient cells to genotoxic agents through mitotic delay. 2009 Mol. Cancer Ther. pmid:19723888
Vamadevan AS et al. Regulation of Toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis. 2010 Innate Immun pmid:19710105
Olsen CA and Ghadiri MR Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides. 2009 J. Med. Chem. pmid:19705846
Yamanaka K et al. Acetylation level of histone H3 in early embryonic stages affects subsequent development of miniature pig somatic cell nuclear transfer embryos. 2009 J. Reprod. Dev. pmid:19700928
Guo W et al. Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition. 2009 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:19700647
Davies GF et al. Troglitazone inhibits histone deacetylase activity in breast cancer cells. 2010 Cancer Lett. pmid:19699029
Ma XX et al. Histone deacetylase inhibitor trichostatin A modulates cell cycles in A2780 human ovarian cancer cell lines. 2009 Eur. J. Gynaecol. Oncol. pmid:19697617
Carambula SF et al. Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation. 2009 Biochem. Biophys. Res. Commun. pmid:19665989
Dagtas AS et al. Histone deacetylase inhibitor uses p21(Cip1) to maintain anergy in CD4+ T cells. 2009 Int. Immunopharmacol. pmid:19664724
Hong Z et al. Microarray study of mechanism of trichostatin a inducing apoptosis of Molt-4 cells. 2009 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:19662360
Pang M et al. Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. 2009 Am. J. Physiol. Renal Physiol. pmid:19640900
Shiau RJ et al. Genistein and beta-carotene enhance the growth-inhibitory effect of trichostatin A in A549 cells. 2010 Eur J Nutr pmid:19639378
Imesch P et al. MLH1 protects from resistance acquisition by the histone deacetylase inhibitor trichostatin A in colon tumor cells. 2009 Int. J. Oncol. pmid:19639184
Chandrasekaran S et al. Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes. 2009 FASEB J. pmid:19638401
Song S et al. Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1. 2010 Cardiovasc. Res. pmid:19633316
Giustiniani J et al. Basal endothelial nitric oxide synthase (eNOS) phosphorylation on Ser(1177) occurs in a stable microtubule- and tubulin acetylation-dependent manner. 2009 Exp. Cell Res. pmid:19632222
Ma GD et al. [Role of histone deacetylase in inhibiting invasion of human gastric carcinoma cell line SGC-7901 by PPARgamma-mediated pathway]. 2009 Ai Zheng pmid:19624894
Fujii K et al. Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells. 2009 Cell Prolif. pmid:19614672
Monks A et al. Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts. 2009 Anticancer Drugs pmid:19606018
Rahim R and Strobl JS Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells. 2009 Anticancer Drugs pmid:19584707
Thiel A et al. 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. 2009 Clin. Cancer Res. pmid:19584167
Watson JA et al. Hyperacetylation in prostate cancer induces cell cycle aberrations, chromatin reorganization and altered gene expression profiles. 2010 J. Cell. Mol. Med. pmid:19583812
Sawarkar R et al. Histone deacetylases regulate multicellular development in the social amoeba Dictyostelium discoideum. 2009 J. Mol. Biol. pmid:19576222
Wang XX and Fu L [Recent advances in DNA demethylation in tumor therapy]. 2009 Zhonghua Bing Li Xue Za Zhi pmid:19575888
Gan YH and Zhang S PTEN/AKT pathway involved in histone deacetylases inhibitor induced cell growth inhibition and apoptosis of oral squamous cell carcinoma cells. 2009 Oral Oncol. pmid:19574087
Lee JH et al. Structural and functional studies of the yeast class II Hda1 histone deacetylase complex. 2009 J. Mol. Biol. pmid:19573535
Ma XL et al. [Construction of anti-sense cDNA library of human breast cancer cells during apoptosis induced by trichostatin A and preliminary screening of essential genes]. 2009 Zhonghua Yi Xue Za Zhi pmid:19567099
Tian F et al. NMDA receptor activation induces differential epigenetic modification of Bdnf promoters in hippocampal neurons. 2010 Amino Acids pmid:19565326
Jonsen MD et al. The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domain. 2009 Mol. Endocrinol. pmid:19556346
Noh H et al. Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury. 2009 Am. J. Physiol. Renal Physiol. pmid:19553350
Hsu PY et al. Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells. 2009 Cancer Res. pmid:19549897
Moon C et al. Use of epigenetic modification to induce FOXP3 expression in naïve T cells. 2009 Transplant. Proc. pmid:19545742
Dubois F et al. Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni. 2009 Mol. Biochem. Parasitol. pmid:19538992
Casero RA and Woster PM Recent advances in the development of polyamine analogues as antitumor agents. 2009 J. Med. Chem. pmid:19534534
Chen IH et al. Cytotoxic triterpenoids from the stems of Microtropis japonica. 2009 J. Nat. Prod. pmid:19534471
Link PA et al. Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells. 2009 Mol. Cancer Res. pmid:19531572
Nadasi E et al. Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. 2009 Anticancer Res. pmid:19528494
Sugimura S et al. Interspecies somatic cell nucleus transfer with porcine oocytes as recipients: A novel bioassay system for assessing the competence of canine somatic cells to develop into embryos. 2009 Theriogenology pmid:19524287
Takaya T et al. MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells. 2009 Circ. J. pmid:19521018
Nakajima S et al. Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231. 2009 Oncol. Rep. pmid:19513516
Chang J et al. The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons. 2009 J. Cell. Sci. pmid:19509051
Bonetto A et al. Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. 2009 Curr Cancer Drug Targets pmid:19508174
Kondo T et al. Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas. 2009 Lab. Invest. pmid:19506552
Ku WC et al. Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. 2009 Mol. Cell Proteomics pmid:19505873
Pulukuri SM et al. Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer. 2009 Oncogene pmid:19503093
Araki H et al. Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues. 2009 Exp. Hematol. pmid:19501128