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Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. |
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Biol. Chem. |
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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. |
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The mouse tumor cell lines EL4 and RMA display mosaic expression of NK-related and certain other surface molecules and appear to have a common origin. |
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Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes. |
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IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a. |
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Cytokine |
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Cancer Res. |
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Cancer Res. |
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Endocrinology |
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Biol. Chem. |
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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. |
2001 |
Cancer Chemother. Pharmacol. |
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The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases. |
2001 |
Mol. Endocrinol. |
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The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells. |
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Nucleic Acids Res. |
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Involvement of histone H4 acetylation in the epigenetic inheritance of different activity states of maternally and paternally derived genomes in the mealybug Planococcus citri. |
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Chromosoma |
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Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. |
2001 |
Haematologica |
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DNA methylation regulates placental lactogen I gene expression. |
2001 |
Endocrinology |
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Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
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Trichostatin A inhibits beta-casein expression in mammary epithelial cells. |
2001 |
J. Cell. Biochem. |
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Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor. |
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DNA Cell Biol. |
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Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. |
2001 |
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Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis. |
2001 |
Expert Opin Investig Drugs |
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Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. |
2001 |
Biochem. Pharmacol. |
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Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development. |
2001 |
Zygote |
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Biol. Reprod. |
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Genes modulated by histone acetylation as new effectors of butyrate activity. |
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FEBS Lett. |
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J. Immunol. |
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In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice. |
2001 |
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Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. |
2001 |
Nat. Cell Biol. |
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5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription. |
2001 |
Mol. Endocrinol. |
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Design and synthesis of a novel class of histone deacetylase inhibitors. |
2001 |
Bioorg. Med. Chem. Lett. |
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Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. |
2001 |
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Isolation and sequencing of infectious clones of feline foamy virus and a human/feline foamy virus Env chimera. |
2001 |
J. Gen. Virol. |
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A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting. |
2001 |
J. Hum. Genet. |
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Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. |
2001 |
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