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Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). |
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The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
2001 |
Cell. Mol. Life Sci. |
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An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. |
2001 |
Int. J. Mol. Med. |
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Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
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Nucleic Acids Res. |
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Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. |
2001 |
Jpn. J. Cancer Res. |
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Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. |
2001 |
Carcinogenesis |
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Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. |
2001 |
Cancer Res. |
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The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). |
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The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase. |
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Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2. |
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Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1. |
2001 |
Biochem. Biophys. Res. Commun. |
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Regulation of the rat NHE3 gene promoter by sodium butyrate. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. |
2001 |
Cancer Chemother. Pharmacol. |
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The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases. |
2001 |
Mol. Endocrinol. |
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The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells. |
2001 |
Mutat. Res. |
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Telomerase activation by histone deacetylase inhibitor in normal cells. |
2001 |
Nucleic Acids Res. |
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Involvement of histone H4 acetylation in the epigenetic inheritance of different activity states of maternally and paternally derived genomes in the mealybug Planococcus citri. |
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Chromosoma |
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Marianna P et al. |
Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. |
2001 |
Haematologica |
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DNA methylation regulates placental lactogen I gene expression. |
2001 |
Endocrinology |
pmid:11459782
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Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
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Trichostatin A inhibits beta-casein expression in mammary epithelial cells. |
2001 |
J. Cell. Biochem. |
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Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor. |
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DNA Cell Biol. |
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Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. |
2001 |
Am. J. Hematol. |
pmid:11754398
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Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis. |
2001 |
Expert Opin Investig Drugs |
pmid:11785457
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Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
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Negative regulation of bcl-2 expression by p53 in hematopoietic cells. |
2001 |
Oncogene |
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Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. |
2001 |
Thyroid |
pmid:11349829
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Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. |
2001 |
Int. J. Cancer |
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The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. |
2001 |
EMBO J. |
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Increased transcription levels induce higher mutation rates in a hypermutating cell line. |
2001 |
J. Immunol. |
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Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. |
2001 |
Biochem. Pharmacol. |
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Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development. |
2001 |
Zygote |
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p21 gene regulation during enterocyte differentiation. |
2001 |
J. Surg. Res. |
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Regulation of zygotic gene activation in the preimplantation mouse embryo: global activation and repression of gene expression. |
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Biol. Reprod. |
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Genes modulated by histone acetylation as new effectors of butyrate activity. |
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FEBS Lett. |
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Chromatin remodeling at the Ig loci prior to V(D)J recombination. |
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J. Immunol. |
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Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
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Mol. Cell. Biol. |
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In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice. |
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Jpn. J. Cancer Res. |
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Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. |
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Nat. Cell Biol. |
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Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. |
2001 |
Cancer Res. |
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Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11134513
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Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
2001 |
J. Biol. Chem. |
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Griswold MD et al. |
Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11223181
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Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. |
2001 |
Mol. Cell. Biol. |
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Newell-Price J et al. |
The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression. |
2001 |
Mol. Endocrinol. |
pmid:11158338
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Kamitani H et al. |
Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma. |
2001 |
Carcinogenesis |
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Inhibition of histone deacetylation induces constitutive derepression of the beta interferon promoter and confers antiviral activity. |
2001 |
J. Virol. |
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Kuwahara K et al. |
The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11238943
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