Endo M et al. |
Novel gender-related regulation of CYP2C12 gene expression in rats. |
2005 |
Mol. Endocrinol. |
pmid:15661834
|
Schmittwolf C et al. |
In vivo haematopoietic activity is induced in neurosphere cells by chromatin-modifying agents. |
2005 |
EMBO J. |
pmid:15660132
|
Marsili G et al. |
Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15659847
|
Li Y et al. |
Histone deacetylation is required for progression through mitosis in tobacco cells. |
2005 |
Plant J. |
pmid:15659094
|
Danam RP et al. |
Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins. |
2005 |
Mol. Cancer Ther. |
pmid:15657354
|
Huang H et al. |
MEIS C termini harbor transcriptional activation domains that respond to cell signaling. |
2005 |
J. Biol. Chem. |
pmid:15654074
|
Kemp MG et al. |
The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells. |
2005 |
Nucleic Acids Res. |
pmid:15653633
|
Shindo N et al. |
The ESC-E(Z) complex participates in the hedgehog signaling pathway. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15652519
|
Kang J et al. |
Antioxidants and trichostatin A synergistically protect against in vitro cytotoxicity of Ni2+ in human hepatoma cells. |
2005 |
Toxicol In Vitro |
pmid:15649630
|
Choi JH et al. |
Trichostatin A attenuates airway inflammation in mouse asthma model. |
2005 |
Clin. Exp. Allergy |
pmid:15649272
|
Huang W et al. |
Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex. |
2005 |
J. Biol. Chem. |
pmid:15647279
|
Farrajota K et al. |
Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism. |
2005 |
Arthritis Rheum. |
pmid:15641079
|
Senawong T et al. |
BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression. |
2005 |
Arch. Biochem. Biophys. |
pmid:15639232
|
Kondo T et al. |
Loss of heterozygosity and histone hypoacetylation of the PINX1 gene are associated with reduced expression in gastric carcinoma. |
2005 |
Oncogene |
pmid:15637589
|
Maxhimer JB et al. |
Induction of apoptosis of lung and esophageal cancer cells treated with the combination of histone deacetylase inhibitor (trichostatin A) and protein kinase C inhibitor (calphostin C). |
2005 |
J. Thorac. Cardiovasc. Surg. |
pmid:15632825
|
Ezzat S et al. |
The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility. |
2005 |
Mol. Endocrinol. |
pmid:15618287
|
Bottardi S et al. |
Onset and inheritance of abnormal epigenetic regulation in hematopoietic cells. |
2005 |
Hum. Mol. Genet. |
pmid:15615768
|
Fujisawa K et al. |
Epigenetic status and aberrant expression of the maspin gene in human hepato-biliary tract carcinomas. |
2005 |
Lab. Invest. |
pmid:15608662
|
Zhao Y et al. |
Histone acetylation regulates both transcription initiation and elongation of hsp22 gene in Drosophila. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15607742
|
Bayart E et al. |
A major role for mitotic CDC2 kinase inactivation in the establishment of the mitotic DNA damage checkpoint. |
2004 |
Cancer Res. |
pmid:15604258
|
Goeman F et al. |
Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras. |
2005 |
Mol. Cell. Biol. |
pmid:15601862
|
Davidson SM et al. |
The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin. |
2005 |
Chembiochem |
pmid:15593114
|
Karasawa Y and Okisaka S |
Inhibition of histone deacetylation by butyrate induces morphological changes in Y79 retinoblastoma cells. |
2004 Nov-Dec |
Jpn. J. Ophthalmol. |
pmid:15592778
|
Sato N et al. |
Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma. |
2005 |
Oncogene |
pmid:15592528
|
Alao JP et al. |
Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines. |
2004 |
Clin. Cancer Res. |
pmid:15585645
|
Varshochi R et al. |
ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line. |
2005 |
J. Biol. Chem. |
pmid:15557281
|
Ramakrishnan G et al. |
Histone acetyltransferases and deacetylase in Entamoeba histolytica. |
2004 |
Mol. Biochem. Parasitol. |
pmid:15555732
|
Hammond SM et al. |
Negative regulatory elements are present in the human LMO2 oncogene and may contribute to its expression in leukemia. |
2005 |
Leuk. Res. |
pmid:15541480
|
Kawano T et al. |
Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect. |
2004 Sep-Oct |
Anticancer Res. |
pmid:15517875
|
El-Khoury V et al. |
Effects of the histone deacetylase inhibitor trichostatin A on nuclear texture and c-jun gene expression in drug-sensitive and drug-resistant human H69 lung carcinoma cells. |
2004 |
Cytometry A |
pmid:15517561
|
Wang S and Zhu J |
The hTERT gene is embedded in a nuclease-resistant chromatin domain. |
2004 |
J. Biol. Chem. |
pmid:15516693
|
Chang S and Pikaard CS |
Transcript profiling in Arabidopsis reveals complex responses to global inhibition of DNA methylation and histone deacetylation. |
2005 |
J. Biol. Chem. |
pmid:15516340
|
Lin AC et al. |
The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors. |
2004 |
J. Biol. Chem. |
pmid:15507435
|
De La Fuente R et al. |
Major chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes is dispensable for global transcriptional silencing but required for centromeric heterochromatin function. |
2004 |
Dev. Biol. |
pmid:15501230
|
Canes D et al. |
Histone deacetylase inhibitors upregulate plakoglobin expression in bladder carcinoma cells and display antineoplastic activity in vitro and in vivo. |
2005 |
Int. J. Cancer |
pmid:15499627
|
Spengler ML et al. |
Sumoylation of internally initiated Sp3 isoforms regulates transcriptional repression via a Trichostatin A-insensitive mechanism. |
2005 |
Cell. Signal. |
pmid:15494207
|
Emmans VC et al. |
Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression. |
2004 |
Biochem. Soc. Trans. |
pmid:15494029
|
Yee SB et al. |
Trichostatin A induces apoptosis of p815 mastocytoma cells in histone acetylation- and mitochondria-dependent fashion. |
2004 |
Int. J. Oncol. |
pmid:15492835
|
Alikhani-Koopaei R et al. |
Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. |
2004 |
J. Clin. Invest. |
pmid:15489962
|
Gius D et al. |
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. |
2004 |
Cancer Cell |
pmid:15488759
|
Alcendor RR et al. |
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. |
2004 |
Circ. Res. |
pmid:15486319
|
Spenger A et al. |
Influence of promoter choice and trichostatin A treatment on expression of baculovirus delivered genes in mammalian cells. |
2004 |
Protein Expr. Purif. |
pmid:15477077
|
Li H and Wu X |
Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474507
|
Ladd PD et al. |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. |
2004 |
Gene |
pmid:15474314
|
Vaquero A et al. |
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. |
2004 |
Mol. Cell |
pmid:15469825
|
Sangster-Guity N et al. |
Molecular profiling of embryonal carcinoma cells following retinoic acid or histone deacetylase inhibitor treatment. |
2004 |
Cancer Biol. Ther. |
pmid:15467438
|
Lee HS et al. |
Gene expression analysis in human gastric cancer cell line treated with trichostatin A and S-adenosyl-L-homocysteine using cDNA microarray. |
2004 |
Biol. Pharm. Bull. |
pmid:15467184
|
Nan X et al. |
Potent stimulation of gene expression by histone deacetylase inhibitors on transiently transfected DNA. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15465025
|
Jori FP et al. |
RB and RB2/p130 genes demonstrate both specific and overlapping functions during the early steps of in vitro neural differentiation of marrow stromal stem cells. |
2005 |
Cell Death Differ. |
pmid:15459751
|
Sarg B et al. |
Histone H4 hyperacetylation precludes histone H4 lysine 20 trimethylation. |
2004 |
J. Biol. Chem. |
pmid:15456746
|
Heltweg B et al. |
Subtype selective substrates for histone deacetylases. |
2004 |
J. Med. Chem. |
pmid:15456267
|
Uramoto H et al. |
p73 competes with co-activators and recruits histone deacetylase to NF-Y in the repression of PDGF beta-receptor. |
2004 |
J. Cell. Sci. |
pmid:15454570
|
Jose B et al. |
Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15454224
|
Chiba T et al. |
Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells. |
2004 |
Oncology |
pmid:15452378
|
Zelko IN and Folz RJ |
Sp1 and Sp3 transcription factors mediate trichostatin A-induced and basal expression of extracellular superoxide dismutase. |
2004 |
Free Radic. Biol. Med. |
pmid:15451065
|
Fan X et al. |
Regulation of RANKL promoter activity is associated with histone remodeling in murine bone stromal cells. |
2004 |
J. Cell. Biochem. |
pmid:15389882
|
Frønsdal K and Saatcioglu F |
Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells. |
2005 |
Prostate |
pmid:15389787
|
Chen JS and Faller DV |
Histone deacetylase inhibition-mediated post-translational elevation of p27KIP1 protein levels is required for G1 arrest in fibroblasts. |
2005 |
J. Cell. Physiol. |
pmid:15389542
|
Davis FJ et al. |
Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility. |
2005 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:15388503
|
Kim MK and Carroll WL |
Autoregulation of the N-myc gene is operative in neuroblastoma and involves histone deacetylase 2. |
2004 |
Cancer |
pmid:15382088
|
Laeng P et al. |
The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells. |
2004 |
J. Neurochem. |
pmid:15379904
|
Moore PS et al. |
Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cells. |
2004 |
Biochim. Biophys. Acta |
pmid:15363630
|
Vaghefi H and Neet KE |
Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation. |
2004 |
Oncogene |
pmid:15361854
|
Boehrer S et al. |
In the erythroleukemic cell line HEL Prostate-apoptosis-response-gene-4 (par-4) fails to down-regulate Bcl-2 and to promote apoptosis. |
2004 |
Leuk. Lymphoma |
pmid:15359646
|
Yokota T et al. |
Trichostatin A activates p18INK4c gene: differential activation and cooperation with p19INK4d gene. |
2004 |
FEBS Lett. |
pmid:15358560
|
Tang XX et al. |
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma. |
2004 |
Clin. Cancer Res. |
pmid:15355914
|
Korkmaz CG et al. |
Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants. |
2004 |
J. Endocrinol. |
pmid:15350180
|
Tao D et al. |
Trichostatin A extends the lifespan of Drosophila melanogaster by elevating hsp22 expression. |
2004 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:15346199
|
Cosio BG et al. |
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. |
2004 |
J. Exp. Med. |
pmid:15337792
|
Liu CJ et al. |
Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. |
2004 |
J. Biol. Chem. |
pmid:15337766
|
Chiba T et al. |
Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells. |
2004 |
J. Hepatol. |
pmid:15336447
|
Schultz BE et al. |
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. |
2004 |
Biochemistry |
pmid:15323567
|
Roh MS et al. |
Mechanism of histone deacetylase inhibitor Trichostatin A induced apoptosis in human osteosarcoma cells. |
2004 |
Apoptosis |
pmid:15314286
|
Facchetti F et al. |
Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors. |
2004 |
Apoptosis |
pmid:15314285
|
Myzak MC et al. |
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. |
2004 |
Cancer Res. |
pmid:15313918
|
Chen YX et al. |
Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines. |
2004 |
World J. Gastroenterol. |
pmid:15309711
|
Gaudier E et al. |
Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:15308471
|
Yanaihara N et al. |
Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer. |
2004 |
Int. J. Cancer |
pmid:15305387
|
Fishel ML et al. |
Effect of cell cycle inhibition on Cisplatin-induced cytotoxicity. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15304523
|
Tóth KF et al. |
Trichostatin A-induced histone acetylation causes decondensation of interphase chromatin. |
2004 |
J. Cell. Sci. |
pmid:15292402
|
Fenic I et al. |
In vivo effects of histone-deacetylase inhibitor trichostatin-A on murine spermatogenesis. |
2004 Sep-Oct |
J. Androl. |
pmid:15292114
|
Iijima K et al. |
Granulocytic differentiation of leukemic cells with t(9;11)(p22;q23) induced by all-trans-retinoic acid. |
2004 |
Leuk. Lymphoma |
pmid:15291362
|
Joung KE et al. |
Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells. |
2004 |
Arch. Pharm. Res. |
pmid:15283467
|
Akimoto T |
[Potentiation of radiation-induced cell killing by histone deacetylase inhibitor]. |
2004 |
Nippon Rinsho |
pmid:15283155
|
Vanhaecke T et al. |
Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures. |
2004 |
Biochem. Pharmacol. |
pmid:15276083
|
Garfinkel MD et al. |
Multigenerational selection and detection of altered histone acetylation and methylation patterns: toward a quantitative epigenetics in Drosophila. |
2004 |
Methods Mol. Biol. |
pmid:15273410
|
Liu C and Xu D |
Inhibition of histone deacetylases. |
2004 |
Methods Mol. Biol. |
pmid:15273406
|
Levenson JM et al. |
Regulation of histone acetylation during memory formation in the hippocampus. |
2004 |
J. Biol. Chem. |
pmid:15273246
|
Sanderson L et al. |
Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice. |
2004 |
Drug Metab. Dispos. |
pmid:15269190
|
Schauber J et al. |
Histone-deacetylase inhibitors induce the cathelicidin LL-37 in gastrointestinal cells. |
2004 |
Mol. Immunol. |
pmid:15261456
|
Marengo E et al. |
Identification of the regulatory proteins in human pancreatic cancers treated with Trichostatin A by 2D-PAGE maps and multivariate statistical analysis. |
2004 |
Anal Bioanal Chem |
pmid:15257427
|
Aggarwal BD and Calvi BR |
Chromatin regulates origin activity in Drosophila follicle cells. |
2004 |
Nature |
pmid:15254542
|
Gilchrist S et al. |
Nuclear organization of centromeric domains is not perturbed by inhibition of histone deacetylases. |
2004 |
Chromosome Res. |
pmid:15254368
|
Jin B and Ryu DY |
Regulation of CYP1A2 by histone deacetylase inhibitors in mouse hepatocytes. |
2004 |
J. Biochem. Mol. Toxicol. |
pmid:15252868
|
Kang J et al. |
Synergistic killing of human leukemia cells by antioxidants and trichostatin A. |
2004 |
Cancer Chemother. Pharmacol. |
pmid:15248029
|
De La Fuente R et al. |
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. |
2004 |
Dev. Biol. |
pmid:15242786
|
Kim JH et al. |
Susceptibility and radiosensitization of human glioblastoma cells to trichostatin A, a histone deacetylase inhibitor. |
2004 |
Int. J. Radiat. Oncol. Biol. Phys. |
pmid:15234053
|
Chen WK et al. |
[Effect of trichostatin A on histone acetylation level and apoptosis in HL-60 cells]. |
2004 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:15228659
|
Naruse Y et al. |
Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation. |
2004 |
Mol. Cell. Biol. |
pmid:15226430
|
Mao DY et al. |
Promoter-binding and repression of PDGFRB by c-Myc are separable activities. |
2004 |
Nucleic Acids Res. |
pmid:15226411
|