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Resetting the epigenetic histone code in the MRL-lpr/lpr mouse model of lupus by histone deacetylase inhibition. |
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Epstein-Barr virus-infected Akata cells are sensitive to histone deacetylase inhibitor TSA-provoked apoptosis. |
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Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells. |
2006 |
Cancer Lett. |
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Dual effects of histone deacetylase inhibition by trichostatin A on endothelial nitric oxide synthase expression in endothelial cells. |
2006 |
Biochem. Biophys. Res. Commun. |
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Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin. |
2006 |
Mol. Biol. Cell |
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Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. |
2006 |
Mol. Cell. Biol. |
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Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer. |
2006 |
Biochem. Biophys. Res. Commun. |
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Methyl CpG-binding domain protein 3 mediates cancer-selective cytotoxicity by histone deacetylase inhibitors via differential transcriptional reprogramming in lung cancer cells. |
2005 |
Cancer Res. |
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Pazmany T and Tomasi TB |
The major histocompatibility complex class II transactivator is differentially regulated by interferon-gamma and transforming growth factor-beta in microglial cells. |
2006 |
J. Neuroimmunol. |
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NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. |
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Inheritable histone H4 acetylation of somatic chromatins in cloned embryos. |
2006 |
J. Biol. Chem. |
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HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion. |
2006 |
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Effect of trichostatin A, a histone deacetylase inhibitor, on glioma proliferation in vitro by inducing cell cycle arrest and apoptosis. |
2005 |
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Trichostatin A increases the thermosensitivity of human glioblastoma A172 cells. |
2006 |
Neurosci. Lett. |
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Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer. |
2006 |
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Bai T et al. |
A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells. |
2006 |
Int. J. Oncol. |
pmid:16391806
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Chen LJ et al. |
[hCG-PLZF-RARalpha/hCG-RARalpha-PLZF transgenic mice developing into leukemia]. |
2005 |
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[Antineoplastic effect of valproic acid and trichostatin on HL-60 and K562 cells]. |
2005 |
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Hansen KR et al. |
Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1. |
2006 |
Nucleic Acids Res. |
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Fischer S et al. |
Histone acetylation dependent allelic expression imbalance of BAPX1 in patients with the oculo-auriculo-vertebral spectrum. |
2006 |
Hum. Mol. Genet. |
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Bieler A et al. |
Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520. |
2006 |
Hum. Gene Ther. |
pmid:16409125
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Lo PK et al. |
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. |
2006 |
Cancer Biol. Ther. |
pmid:16410723
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Yamamoto G et al. |
Correlation of invasion and metastasis of cancer cells, and expression of the RAD21 gene in oral squamous cell carcinoma. |
2006 |
Virchows Arch. |
pmid:16416296
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D'Andrea M et al. |
Protein kinase C theta co-operates with calcineurin in the activation of slow muscle genes in cultured myogenic cells. |
2006 |
J. Cell. Physiol. |
pmid:16419034
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Deng G et al. |
Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. |
2006 |
Int. J. Cancer |
pmid:16425274
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Huang L et al. |
Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression. |
2006 |
Neurosci. Lett. |
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Nambiar MP et al. |
Transcriptional induction of cholinesterase expression and protection against chemical warfare nerve agents. |
2005 |
Chem. Biol. Interact. |
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Fandy TE and Srivastava RK |
Trichostatin A sensitizes TRAIL-resistant myeloma cells by downregulation of the antiapoptotic Bcl-2 proteins. |
2006 |
Cancer Chemother. Pharmacol. |
pmid:16435155
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Gialitakis M et al. |
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. |
2006 |
Nucleic Acids Res. |
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Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents. |
2006 |
Exp. Hematol. |
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Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells. |
2006 |
Int. J. Oncol. |
pmid:16465382
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Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53. |
2006 |
Clin. Cancer Res. |
pmid:16467109
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Osborn NK et al. |
Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. |
2006 |
Clin. Gastroenterol. Hepatol. |
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Tumor suppressor p53 regulates heparanase gene expression. |
2006 |
Oncogene |
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Telomere position effect and silencing of transgenes near telomeres in the mouse. |
2006 |
Mol. Cell. Biol. |
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Role of histone acetylation in reprogramming of somatic nuclei following nuclear transfer. |
2006 |
Biol. Reprod. |
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2006 |
J. Biol. Chem. |
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Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
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Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. |
2006 |
Ann. Thorac. Surg. |
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Invited commentary. |
2006 |
Ann. Thorac. Surg. |
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Song YF et al. |
High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. |
2006 |
J. Clin. Pathol. |
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Kim MY et al. |
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. |
2006 |
Mol. Endocrinol. |
pmid:16497729
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Alao JP et al. |
The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines. |
2006 |
Mol. Cancer |
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Alao JP et al. |
Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells. |
2006 |
Mol. Cancer |
pmid:16504004
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Ostapkowicz A et al. |
Lipid rafts remodeling in estrogen receptor-negative breast cancer is reversed by histone deacetylase inhibitor. |
2006 |
Mol. Cancer Ther. |
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Angiostatic activity of DNA methyltransferase inhibitors. |
2006 |
Mol. Cancer Ther. |
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Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha. |
2006 |
Mol. Cell. Biol. |
pmid:16507982
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Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells. |
2006 |
Mol. Cancer Res. |
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Activities of maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK) are not required for the global histone deacetylation observed after germinal vesicle breakdown (GVBD) in porcine oocytes. |
2006 |
Reproduction |
pmid:16514187
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Bates EA et al. |
Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity. |
2006 |
J. Neurosci. |
pmid:16525063
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Chuang HC et al. |
Histone deacetylase 3 binds to and regulates the GCMa transcription factor. |
2006 |
Nucleic Acids Res. |
pmid:16528103
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Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes. |
2006 |
Toxicol. Sci. |
pmid:16531468
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Gastaldi T et al. |
Plakoglobin is differentially expressed in alveolar and embryonal rhabdomyosarcoma and is regulated by DNA methylation and histone acetylation. |
2006 |
Carcinogenesis |
pmid:16537559
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Tada Y et al. |
Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer. |
2006 |
J. Natl. Cancer Inst. |
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Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA. |
2006 |
Mol. Cell. Biol. |
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Hsiao CH et al. |
Fetal hemoglobin induction by histone deacetylase inhibitors involves generation of reactive oxygen species. |
2006 |
Exp. Hematol. |
pmid:16543060
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Gagnon JF et al. |
Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. |
2006 |
Clin. Cancer Res. |
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The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis. |
2006 |
Cell Death Differ. |
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Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation. |
2006 |
Oncogene |
pmid:16568090
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Piacentini P et al. |
Trichostatin A enhances the response of chemotherapeutic agents in inhibiting pancreatic cancer cell proliferation. |
2006 |
Virchows Arch. |
pmid:16568310
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Woo HJ et al. |
Induction of apoptosis and inhibition of telomerase activity by trichostatin A, a histone deacetylase inhibitor, in human leukemic U937 cells. |
2007 |
Exp. Mol. Pathol. |
pmid:16574101
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Nusinzon I and Horvath CM |
Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation. |
2006 |
Mol. Cell. Biol. |
pmid:16581785
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Stefanovsky V and Moss T |
Regulation of rRNA synthesis in human and mouse cells is not determined by changes in active gene count. |
2006 |
Cell Cycle |
pmid:16582637
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Wang Q et al. |
Histone deacetylation is required for orderly meiosis. |
2006 |
Cell Cycle |
pmid:16582639
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Jaalouk DE et al. |
Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors. |
2006 |
Virol. J. |
pmid:16603064
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Banwell CM et al. |
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. |
2006 |
Clin. Cancer Res. |
pmid:16609009
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Januchowski R et al. |
Trichostatin A down-regulate DNA methyltransferase 1 in Jurkat T cells. |
2007 |
Cancer Lett. |
pmid:16624484
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Magnaghi-Jaulin L and Jaulin C |
Histone deacetylase activity is necessary for chromosome condensation during meiotic maturation in Xenopus laevis. |
2006 |
Chromosome Res. |
pmid:16628502
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Pavan Kumar P et al. |
Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. |
2006 |
Mol. Cell |
pmid:16630892
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Uchida H et al. |
Human endometrial cytodifferentiation by histone deacetylase inhibitors. |
2006 |
Hum. Cell |
pmid:16643606
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Jung EJ et al. |
Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir. |
2007 |
Cancer Lett. |
pmid:16647201
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Akiyama T et al. |
Inadequate histone deacetylation during oocyte meiosis causes aneuploidy and embryo death in mice. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16651529
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Hernandez M et al. |
A histone deacetylation-dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells. |
2006 |
Prostate |
pmid:16652385
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Armstrong K et al. |
NF-kappaB activation upregulates fibroblast growth factor 8 expression in prostate cancer cells. |
2006 |
Prostate |
pmid:16683270
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Wischnewski F et al. |
Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. |
2006 |
Mol. Cancer Res. |
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Ibanez de Caceres I et al. |
Identification of novel target genes by an epigenetic reactivation screen of renal cancer. |
2006 |
Cancer Res. |
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Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation. |
2006 |
Cancer Res. |
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Thyroid hormone-mediated negative transcriptional regulation of Necdin expression. |
2006 |
J. Mol. Endocrinol. |
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Yamada N et al. |
MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. |
2006 |
Int. J. Cancer |
pmid:16721789
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Kim Y et al. |
Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. |
2006 |
J. Steroid Biochem. Mol. Biol. |
pmid:16723222
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Santander VS et al. |
Tubulin must be acetylated in order to form a complex with membrane Na(+),K (+)-ATPase and to inhibit its enzyme activity. |
2006 |
Mol. Cell. Biochem. |
pmid:16733802
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Kong Y et al. |
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. |
2006 |
Circulation |
pmid:16735673
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Dannenberg LO et al. |
Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. |
2006 |
Alcohol. Clin. Exp. Res. |
pmid:16737450
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Cabrero JR et al. |
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. |
2006 |
Mol. Biol. Cell |
pmid:16738306
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Vulcano F et al. |
HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers. |
2006 |
Exp. Cell Res. |
pmid:16739251
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Qi H and Ratnam M |
Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. |
2006 |
Cancer Res. |
pmid:16740727
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Rouhi A et al. |
Plasticity of Ly49g expression is due to epigenetics. |
2007 |
Mol. Immunol. |
pmid:16750269
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Morinobu A et al. |
Trichostatin A cooperates with Fas-mediated signal to induce apoptosis in rheumatoid arthritis synovial fibroblasts. |
2006 |
J. Rheumatol. |
pmid:16755652
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Kwon HS et al. |
Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. |
2006 Mar-Apr |
Biochim. Biophys. Acta |
pmid:16757381
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Vanniasinkam T et al. |
Trichostatin-A enhances adaptive immune responses to DNA vaccination. |
2006 |
J. Clin. Virol. |
pmid:16765083
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Li GC et al. |
Histone deacetylase inhibitor trichostatin A inhibits the growth of bladder cancer cells through induction of p21WAF1 and G1 cell cycle arrest. |
2006 |
Int. J. Urol. |
pmid:16771729
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Zhou C et al. |
Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells. |
2006 |
Int. J. Oncol. |
pmid:16773209
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Tsuji H et al. |
Dynamic and reversible changes in histone H3-Lys4 methylation and H3 acetylation occurring at submergence-inducible genes in rice. |
2006 |
Plant Cell Physiol. |
pmid:16774928
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Kwon O et al. |
NF-kappaB inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells. |
2006 |
Carcinogenesis |
pmid:16774937
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Zhao YM et al. |
Effects of histone deacetylase inhibitors on transcriptional regulation of the hsp70 gene in Drosophila. |
2006 |
Cell Res. |
pmid:16775628
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Sharma D et al. |
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes. |
2006 |
Cancer Res. |
pmid:16778215
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Wu Y and Guo SW |
Inhibition of proliferation of endometrial stromal cells by trichostatin A, RU486, CDB-2914, N-acetylcysteine, and ICI 182780. |
2006 |
Gynecol. Obstet. Invest. |
pmid:16778450
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Iacomino G et al. |
Effects of histone deacetylase inhibitors on p55CDC/Cdc20 expression in HT29 cell line. |
2006 |
J. Cell. Biochem. |
pmid:16795040
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Suuronen T et al. |
Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. |
2006 |
Neurochem. Int. |
pmid:16797784
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Wallace DM et al. |
Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:16799012
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