Arany I et al. |
Epigenetic modifiers exert renal toxicity through induction of p66shc. |
2011 |
Anticancer Res. |
pmid:21965735
|
Sasaki Y et al. |
p53 negatively regulates the hepatoma growth factor HDGF. |
2011 |
Cancer Res. |
pmid:22006999
|
Aoyama K et al. |
Nuclear c-Abl-mediated tyrosine phosphorylation induces chromatin structural changes through histone modifications that include H4K16 hypoacetylation. |
2011 |
Exp. Cell Res. |
pmid:22001646
|
Jeon HG et al. |
Induction of caspase mediated apoptosis and down-regulation of nuclear factor-κB and Akt signaling are involved in the synergistic antitumor effect of gemcitabine and the histone deacetylase inhibitor trichostatin A in human bladder cancer cells. |
2011 |
J. Urol. |
pmid:21944112
|
Hirata H et al. |
Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. |
2011 |
Int. J. Cancer |
pmid:20549706
|
Ohtani K et al. |
Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells. |
2011 |
Circ. Res. |
pmid:21980126
|
Hagiwara H et al. |
Histone deacetylase inhibitor trichostatin A enhances myogenesis by coordinating muscle regulatory factors and myogenic repressors. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:22019851
|
Jafari S et al. |
Epigenetic modification does not determine the time of POU5F1 transcription activation in cloned bovine embryos. |
2011 |
J. Assist. Reprod. Genet. |
pmid:22020531
|
Tseng AS et al. |
HDAC activity is required during Xenopus tail regeneration. |
2011 |
PLoS ONE |
pmid:22022609
|
Rajak H et al. |
2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21875796
|
He HM et al. |
[The effects of a histone deacetylase (HDAC) inhibitor on endotoxin-induced endothelial cell injury]. |
2011 |
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue |
pmid:22005560
|
Sanders YY et al. |
Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts. |
2011 |
Am. J. Respir. Cell Mol. Biol. |
pmid:20724553
|
Xia B et al. |
Chromium(VI) causes down regulation of biotinidase in human bronchial epithelial cells by modifications of histone acetylation. |
2011 |
Toxicol. Lett. |
pmid:21641978
|
Seo SK et al. |
Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. |
2011 |
J Thorac Oncol |
pmid:21642861
|
Acun T et al. |
SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. |
2011 |
BMC Cancer |
pmid:21645397
|
Hou J et al. |
Structure-based optimization of click-based histone deacetylase inhibitors. |
2011 |
Eur J Med Chem |
pmid:21621883
|
Gaub P et al. |
The histone acetyltransferase p300 promotes intrinsic axonal regeneration. |
2011 |
Brain |
pmid:21705428
|
Song K et al. |
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer. |
2011 |
Cancer Biol. Ther. |
pmid:21709440
|
Hauff KD et al. |
Mifepristone treatment results in differential regulation of glycerolipid biosynthesis in baby hamster kidney cells expressing a mifepristone-inducible ABCA1. |
2011 |
Lipids |
pmid:21710238
|
Zhou S et al. |
Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. |
2011 |
Circ. Res. |
pmid:21778425
|
Yoo YE and Ko CP |
Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis. |
2011 |
Exp. Neurol. |
pmid:21712032
|
Sar P et al. |
3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements. |
2011 |
PLoS ONE |
pmid:21687737
|
Cosner CC and Helquist P |
Concise, convergent syntheses of (±)-trichostatin A utilizing a Pd-catalyzed ketone enolate α-alkenylation reaction. |
2011 |
Org. Lett. |
pmid:21688856
|
Kojima S et al. |
Asymmetric leaves2 and Elongator, a histone acetyltransferase complex, mediate the establishment of polarity in leaves of Arabidopsis thaliana. |
2011 |
Plant Cell Physiol. |
pmid:21700721
|
Chik CL et al. |
Histone modifications on the adrenergic induction of type II deiodinase in rat pinealocytes. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21704117
|
Zhang L et al. |
ABA treatment of germinating maize seeds induces VP1 gene expression and selective promoter-associated histone acetylation. |
2011 |
Physiol Plant |
pmid:21679193
|
Lin S et al. |
HIV-1 reactivation induced by apicidin involves histone modification in latently infected cells. |
2011 |
Curr. HIV Res. |
pmid:21631428
|
Jugová A et al. |
Effects of epigenetic-based anti-cancer drugs in leukaemia and multiple myeloma cells. |
2011 |
Cell Biol. Int. |
pmid:21635225
|
Kawasaki H et al. |
Mouse embryonic stem cells inhibit murine cytomegalovirus infection through a multi-step process. |
2011 |
PLoS ONE |
pmid:21407806
|
Li Z et al. |
Epigenetic inactivation of PCDH10 in human prostate cancer cell lines. |
2011 |
Cell Biol. Int. |
pmid:21314642
|
Saiyed ZM et al. |
HIV-1 Tat upregulates expression of histone deacetylase-2 (HDAC2) in human neurons: implication for HIV-associated neurocognitive disorder (HAND). |
2011 |
Neurochem. Int. |
pmid:21315782
|
Fang Y et al. |
Synergistic efficacy in human ovarian cancer cells by histone deacetylase inhibitor TSA and proteasome inhibitor PS-341. |
2011 |
Cancer Invest. |
pmid:21345073
|
Qian Y et al. |
DeltaNp63, a target of DEC1 and histone deacetylase 2, modulates the efficacy of histone deacetylase inhibitors in growth suppression and keratinocyte differentiation. |
2011 |
J. Biol. Chem. |
pmid:21317427
|
Zhang F et al. |
Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis. |
2011 |
PLoS ONE |
pmid:21346816
|
Hizaki K et al. |
Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. |
2011 |
Mod. Pathol. |
pmid:21317879
|
Zhou X et al. |
Trichostatin differentially regulates Th1 and Th2 responses and alleviates rheumatoid arthritis in mice. |
2011 |
J. Clin. Immunol. |
pmid:21305388
|
Meli M et al. |
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells. |
2011 |
Int. J. Oncol. |
pmid:21318222
|
Turovets N et al. |
Human parthenogenetic stem cells produce enriched populations of definitive endoderm cells after trichostatin A pretreatment. |
2011 |
Differentiation |
pmid:21306817
|
Xiao J et al. |
Discovery, synthesis, and biological evaluation of novel SMN protein modulators. |
2011 |
J. Med. Chem. |
pmid:21819082
|
Yang H et al. |
Enrichment of Nur77 mediated by retinoic acid receptor β leads to apoptosis of human hepatocellular carcinoma cells induced by fenretinide and histone deacetylase inhibitors. |
2011 |
Hepatology |
pmid:21319187
|
Patel T et al. |
Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice. |
2011 |
Immunol. Cell Biol. |
pmid:21321581
|
Chaurasia P et al. |
Chromatin-modifying agents promote the ex vivo production of functional human erythroid progenitor cells. |
2011 |
Blood |
pmid:21355088
|
Shi G et al. |
The regulatory role of histone deacetylase inhibitors in Fgf4 expression is dependent on the differentiation state of pluripotent stem cells. |
2011 |
J. Cell. Physiol. |
pmid:21321941
|
Furuta K et al. |
The CKH2/PKL chromatin remodeling factor negatively regulates cytokinin responses in Arabidopsis calli. |
2011 |
Plant Cell Physiol. |
pmid:21357580
|
Fan Y et al. |
Derivation of cloned human blastocysts by histone deacetylase inhibitor treatment after somatic cell nuclear transfer with β-thalassemia fibroblasts. |
2011 |
Stem Cells Dev. |
pmid:21322785
|
Kim YJ et al. |
Comparison of potency between histone deacetylase inhibitors trichostatin A and valproic acid on enhancing in vitro development of porcine somatic cell nuclear transfer embryos. |
2011 |
In Vitro Cell. Dev. Biol. Anim. |
pmid:21359816
|
Jang ER et al. |
Different effect of protein kinase B/Akt and extracellular signal-regulated kinase inhibition on trichostatin A-induced apoptosis in epithelial ovarian carcinoma cell lines. |
2011 |
Mol. Cell. Biochem. |
pmid:21380726
|
Fan T et al. |
EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression. |
2011 |
Mol. Cancer Res. |
pmid:21383005
|
Yang J et al. |
[Study of RASSF1A expression and promoter demethylation in Hep-2 cell line]. |
2011 |
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi |
pmid:21473137
|
Cui XS et al. |
Trichostatin A modulates apoptotic-related gene expression and improves embryo viability in cloned bovine embryos. |
2011 |
Cell Reprogram |
pmid:21473694
|
Chen X et al. |
Design, synthesis and biological evaluation of hydroxamic acid derivatives as potential high density lipoprotein (HDL) receptor CLA-1 up-regulating agents. |
2011 |
Molecules |
pmid:22048700
|
Sun JY et al. |
Histone deacetylase inhibitors demonstrate significant preclinical activity as single agents, and in combination with bortezomib in Waldenström's macroglobulinemia. |
2011 |
Clin Lymphoma Myeloma Leuk |
pmid:21454220
|
Kong QR et al. |
[TSA improve transgenic porcine cloned embryo development and transgene expression]. |
2011 |
Yi Chuan |
pmid:22049689
|
Dávalos-Salas M et al. |
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. |
2011 |
BMC Cancer |
pmid:21663659
|
El-Serafi AT et al. |
Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A. |
2011 |
Differentiation |
pmid:20970916
|
Zhang FQ et al. |
Cell-cycle-dependent variations in the FTIR spectroscopy of HeLa cells treated with trichostatin A. |
2011 |
Guang Pu Xue Yu Guang Pu Fen Xi |
pmid:22007388
|
Nagamine MK et al. |
In vitro inhibitory effect of trichostatin A on canine grade 3 mast cell tumor. |
2011 |
Vet. Res. Commun. |
pmid:21472452
|
Maruoka H et al. |
Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons. |
2011 |
J. Biochem. |
pmid:21908547
|
Biermann J et al. |
Histone deacetylase inhibitors sodium butyrate and valproic acid delay spontaneous cell death in purified rat retinal ganglion cells. |
2011 |
Mol. Vis. |
pmid:21311741
|
Miller L et al. |
Histone deacetylase 1 (HDAC1) participates in the down-regulation of corticotropin releasing hormone gene (crh) expression. |
2011 |
Physiol. Behav. |
pmid:21463644
|
Law AY et al. |
Sp1 is a transcription repressor to stanniocalcin-1 expression in TSA-treated human colon cancer cells, HT29. |
2011 |
J. Cell. Biochem. |
pmid:21465530
|
Blanquart C et al. |
Pharmacological characterization of histone deacetylase inhibitor and tumor cell-growth inhibition properties of new benzofuranone compounds. |
2011 |
Curr Cancer Drug Targets |
pmid:21762083
|
Li S et al. |
Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis. |
2011 |
Mol. Cancer |
pmid:21314984
|
Pang M et al. |
Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins. |
2011 |
J. Cell. Biochem. |
pmid:21465537
|
Wan Y et al. |
Transcriptome profiling reveals a novel role for trichostatin A in antagonizing histone chaperone Chz1 mediated telomere anti-silencing. |
2011 |
FEBS Lett. |
pmid:21763693
|
Kimura T et al. |
Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300. |
2011 |
J Toxicol Sci |
pmid:21467744
|
Zhang CZ et al. |
Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. |
2011 |
Apoptosis |
pmid:21468663
|
Hu Y et al. |
Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize. |
2011 |
PLoS ONE |
pmid:21811564
|
Chen YT et al. |
Isolation of mesenchymal stem cells from human ligamentum flavum: implicating etiology of ligamentum flavum hypertrophy. |
2011 |
Spine |
pmid:21343850
|
Lee MJ et al. |
Trichostatin A promotes the development of bovine somatic cell nuclear transfer embryos. |
2011 |
J. Reprod. Dev. |
pmid:20834196
|
Amoêdo ND et al. |
Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. |
2011 |
PLoS ONE |
pmid:21789245
|
Sengupta S et al. |
Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. |
2011 |
Oncogene |
pmid:20856196
|
Arzenani MK et al. |
Genomic DNA hypomethylation by histone deacetylase inhibition implicates DNMT1 nuclear dynamics. |
2011 |
Mol. Cell. Biol. |
pmid:21791605
|
Costa VL et al. |
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers. |
2011 |
Epigenetics |
pmid:21847011
|
Akagi S et al. |
Treatment with a histone deacetylase inhibitor after nuclear transfer improves the preimplantation development of cloned bovine embryos. |
2011 |
J. Reprod. Dev. |
pmid:20962457
|
Fu S et al. |
Involvement of histone acetylation of Sox17 and Foxa2 promoters during mouse definitive endoderm differentiation revealed by microRNA profiling. |
2011 |
PLoS ONE |
pmid:22132182
|
Mayor R et al. |
Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. |
2011 |
Epigenetics |
pmid:21852760
|
Kumar A et al. |
γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines. |
2011 |
Int. J. Radiat. Biol. |
pmid:21815748
|
Tan L et al. |
Trichostatin A restores Apaf-1 function in chemoresistant ovarian cancer cells. |
2011 |
Cancer |
pmid:20925046
|
Jackson K et al. |
Epigenetic silencing of somatostatin in gastric cancer. |
2011 |
Dig. Dis. Sci. |
pmid:20927589
|
Sahu GK and Cloyd MW |
Latent HIV in primary T lymphocytes is unresponsive to histone deacetylase inhibitors. |
2011 |
Virol. J. |
pmid:21838863
|
Yu D et al. |
Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21840716
|
Atanackovic D et al. |
Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia. |
2011 |
Am. J. Hematol. |
pmid:21898529
|
Mizuno S et al. |
Inhibition of histone deacetylase causes emphysema. |
2011 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:21224215
|
Hai T et al. |
Pluripotency maintenance in mouse somatic cell nuclear transfer embryos and its improvement by treatment with the histone deacetylase inhibitor TSA. |
2011 |
Cell Reprogram |
pmid:21241188
|
Nakamura J et al. |
Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer. |
2011 |
Am. J. Pathol. |
pmid:21281785
|
Puppin C et al. |
In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription. |
2011 |
Cell Oncol (Dordr) |
pmid:21290209
|
Ishiguro K et al. |
Cutting edge: tubulin α functions as an adaptor in NFAT-importin β interaction. |
2011 |
J. Immunol. |
pmid:21278340
|
Ma AN et al. |
Histone deacetylation directs DNA methylation in survivin gene silencing. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21130077
|
Pianta A et al. |
Nucleophosmin delocalization in thyroid tumour cells. |
2011 |
Endocr. Pathol. |
pmid:21258971
|
Gómez MC et al. |
Trichostatin A modified histone covalent pattern and enhanced expression of pluripotent genes in interspecies black-footed cat cloned embryos but did not improve in vitro and in vivo viability. |
2011 |
Cell Reprogram |
pmid:21718106
|
Whitehead L et al. |
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors. |
2011 |
Bioorg. Med. Chem. |
pmid:21723733
|
Yin H et al. |
Histonedeacetylase inhibitor Oxamflatin increase HIV-1 transcription by inducing histone modification in latently infected cells. |
2011 |
Mol. Biol. Rep. |
pmid:21181272
|
Stoppani E et al. |
Point mutated caveolin-3 form (P104L) impairs myoblast differentiation via Akt and p38 signalling reduction, leading to an immature cell signature. |
2011 |
Biochim. Biophys. Acta |
pmid:21182936
|
Puppin C et al. |
Histone deacetylase inhibitors control the transcription and alternative splicing of prohibitin in thyroid tumor cells. |
2011 |
Oncol. Rep. |
pmid:21152868
|
Tsai PF et al. |
Interplay between PKCδ and Sp1 on histone deacetylase inhibitor-mediated Epstein-Barr virus reactivation. |
2011 |
J. Virol. |
pmid:21159880
|
Nandakumar V et al. |
(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells. |
2011 |
Carcinogenesis |
pmid:21209038
|
Ververis K et al. |
Histone deacetylase inhibitors augment doxorubicin-induced DNA damage in cardiomyocytes. |
2011 |
Cell. Mol. Life Sci. |
pmid:21584806
|
Misaki K et al. |
Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice. |
2011 |
Arthritis Res. Ther. |
pmid:21592365
|
Selinger CI et al. |
Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. |
2011 |
J Thorac Oncol |
pmid:21597389
|