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Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor. |
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Cancer Cell |
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Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. |
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Biochemistry |
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The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H1(0) synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study. |
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Trichostatin A, a histone deacetylase inhibitor, down-regulates interleukin-12 transcription in SV-40-transformed lung epithelial cells. |
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Oncogene |
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Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins. |
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Glia |
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N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824). |
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Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities. |
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Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87. |
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Carcinogenesis |
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Acetylated sp3 is a transcriptional activator. |
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The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. |
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Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. |
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Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site. |
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Biochem. Biophys. Res. Commun. |
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Two functionally divergent p53-responsive elements in the rat bradykinin B2 receptor promoter. |
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The SV40 T antigen modulates CBP histone acetyltransferase activity. |
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Nucleic Acids Res. |
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Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene. |
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Nucleic Acids Res. |
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A multistep mechanism for the activation of rearrangement in the immune system. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Trichostatin A suppresses transformation by the v-myb oncogene in BM2 cells. |
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J. Hematother. Stem Cell Res. |
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Acetylation of histone H3 at lysine 9 by ethanol in rat hepatocytes. |
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Biochem. Biophys. Res. Commun. |
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EMBO J. |
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Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine. |
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Biol. Reprod. |
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Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition. |
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Bioorg. Med. Chem. Lett. |
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Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells. |
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Cancer Res. |
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Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. |
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Gut |
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Generation of hepatocyte-like cells from human embryonic stem cells. |
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Cell Transplant |
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Activation of terminal B cell differentiation by inhibition of histone deacetylation. |
2003 |
Mol. Immunol. |
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Fragile X (CGG)n repeats induce a transcriptional repression in cis upon a linked promoter: evidence for a chromatin mediated effect. |
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BMC Mol. Biol. |
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Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation. |
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