Giannini G et al. |
N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19285395
|
Hoque MA et al. |
Cyclic tetrapeptides with thioacetate tails or intramolecular disulfide bridge as potent inhibitors of histone deacetylases. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:23021104
|
Loudni L et al. |
Design, synthesis and biological evaluation of 1,4-benzodiazepine-2,5-dione-based HDAC inhibitors. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17624773
|
Riester D et al. |
Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19457659
|
Shinji C et al. |
Design and synthesis of phthalimide-type histone deacetylase inhibitors. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:16137884
|
Uesato S et al. |
Novel histone deacetylase inhibitors: N-hydroxycarboxamides possessing a terminal bicyclic aryl group. |
2002 |
Bioorg. Med. Chem. Lett. |
pmid:11992774
|
Yu D et al. |
Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21840716
|
Charrier C et al. |
Synthesis of rigid trichostatin A analogs as HDAC inhibitors. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16904890
|
Van Ommeslaeghe K et al. |
Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12749885
|
Suzuki T et al. |
Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17257837
|
Lavoie R et al. |
Design and synthesis of a novel class of histone deacetylase inhibitors. |
2001 |
Bioorg. Med. Chem. Lett. |
pmid:11597413
|
Tobias CA et al. |
Improved recombinant retroviral titers utilizing trichostatin A. |
2000 |
BioTechniques |
pmid:11056820
|
Seo H et al. |
Modulation of immunoglobulin gene conversion in chicken DT40 by enhancing histone acetylation, and its application to antibody engineering. |
2007 |
Biotechnol. Genet. Eng. Rev. |
pmid:18059633
|
Kalaiarasi A et al. |
Copper oxide nanoparticles induce anticancer activity in A549 lung cancer cells by inhibition of histone deacetylase. |
2018 |
Biotechnol. Lett. |
pmid:29116558
|
Liu X et al. |
The improvement of adenovirus vector production by increased expression of coxsackie adenovirus receptor. |
2009 |
Biotechnol. Lett. |
pmid:19330491
|
Kim HJ et al. |
Enhancement of human mesenchymal stem cell differentiation by combination treatment with 5-azacytidine and trichostatin A. |
2016 |
Biotechnol. Lett. |
pmid:26341652
|
Menegola E et al. |
Inhibition of histone deacetylase activity on specific embryonic tissues as a new mechanism for teratogenicity. |
2005 |
Birth Defects Res. B Dev. Reprod. Toxicol. |
pmid:16193500
|
Rahman MM et al. |
Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. |
2003 |
Blood |
pmid:12511413
|
Zhou DC et al. |
Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. |
2002 |
Blood |
pmid:11830487
|
Milhem M et al. |
Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A. |
2004 |
Blood |
pmid:14976039
|
Cao H et al. |
Induction of human gamma globin gene expression by histone deacetylase inhibitors. |
2004 |
Blood |
pmid:12920038
|
Hebbel RP et al. |
The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. |
2010 |
Blood |
pmid:20053759
|
Sadoul K et al. |
HDAC6 controls the kinetics of platelet activation. |
2012 |
Blood |
pmid:22955928
|
Hambach L et al. |
Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. |
2009 |
Blood |
pmid:19096014
|
Petti MC et al. |
Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies. |
2002 |
Blood |
pmid:12130525
|
Araki H et al. |
Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. |
2007 |
Blood |
pmid:17185465
|
Chaurasia P et al. |
Chromatin-modifying agents promote the ex vivo production of functional human erythroid progenitor cells. |
2011 |
Blood |
pmid:21355088
|
Jamaluddin MD et al. |
Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. |
2007 |
Blood |
pmid:17698632
|
Wang X et al. |
Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells. |
2010 |
Blood |
pmid:20858855
|
Witt O et al. |
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. |
2003 |
Blood |
pmid:12393499
|
Smith RD et al. |
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. |
2000 |
Blood |
pmid:10648397
|
Ishiguro K and Sartorelli AC |
Coinduction of embryonic and adult-type globin mRNAs by sodium butyrate and trichostatin A in two murine interleukin-3-dependent bone marrow-derived cell lines. |
1998 |
Blood |
pmid:9834245
|
Li X et al. |
Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos. |
2009 |
Blood |
pmid:19864643
|
Gao C et al. |
Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex. |
2013 |
Blood |
pmid:23287862
|
Chen Z et al. |
BCL11A represses HBG transcription in K562 cells. |
2009 Mar-Apr |
Blood Cells Mol. Dis. |
pmid:19153051
|
Swank RA et al. |
The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced gamma globin expression in somatic cell hybrids and induces gamma gene expression in adult BFUe cultures. |
2003 May-Jun |
Blood Cells Mol. Dis. |
pmid:12737942
|
Xu ZM et al. |
The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage. |
2008 |
BMB Rep |
pmid:18377727
|
Viñuelas J et al. |
Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts. |
2013 |
BMC Biol. |
pmid:23442824
|
Nordström L et al. |
DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells. |
2015 |
BMC Cancer |
pmid:25880212
|
Tong JH et al. |
Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma. |
2010 |
BMC Cancer |
pmid:20525238
|
Moreira JM et al. |
The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses. |
2003 |
BMC Cancer |
pmid:14606959
|
Acun T et al. |
SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. |
2011 |
BMC Cancer |
pmid:21645397
|
Mazières J et al. |
Epigenetic regulation of RhoB loss of expression in lung cancer. |
2007 |
BMC Cancer |
pmid:18047684
|
Tombolan L et al. |
Global DNA methylation profiling uncovers distinct methylation patterns of protocadherin alpha4 in metastatic and non-metastatic rhabdomyosarcoma. |
2016 |
BMC Cancer |
pmid:27842508
|
Hrgovic I et al. |
The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. |
2016 |
BMC Cancer |
pmid:27716272
|
Dávalos-Salas M et al. |
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. |
2011 |
BMC Cancer |
pmid:21663659
|
Kim TW et al. |
Nuclear-encoded mitochondrial MTO1 and MRPL41 are regulated in an opposite epigenetic mode based on estrogen receptor status in breast cancer. |
2013 |
BMC Cancer |
pmid:24160266
|
Zou CF et al. |
Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel. |
2011 |
BMC Cancer |
pmid:21244707
|
Mühlethaler-Mottet A et al. |
Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. |
2006 |
BMC Cancer |
pmid:16930472
|
Puppin C et al. |
HEX expression and localization in normal mammary gland and breast carcinoma. |
2006 |
BMC Cancer |
pmid:16854221
|