Ashburner BP et al. |
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. |
2001 |
Mol. Cell. Biol. |
pmid:11564889
|
Sekita N et al. |
Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. |
2001 |
Jpn. J. Cancer Res. |
pmid:11572762
|
Yin L et al. |
Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. |
2001 |
J. Biol. Chem. |
pmid:11572859
|
Leng SL et al. |
Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. |
2001 |
Carcinogenesis |
pmid:11577001
|
Yang X et al. |
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. |
2001 |
Cancer Res. |
pmid:11585728
|
Abderrahmani A et al. |
The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). |
2001 |
Mol. Cell. Biol. |
pmid:11585908
|
Yoshida M et al. |
Histone deacetylase as a new target for cancer chemotherapy. |
2001 |
Cancer Chemother. Pharmacol. |
pmid:11587361
|
McGuinness MC et al. |
Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
2001 Sep-Oct |
Mol. Genet. Metab. |
pmid:11592822
|
Lavoie R et al. |
Design and synthesis of a novel class of histone deacetylase inhibitors. |
2001 |
Bioorg. Med. Chem. Lett. |
pmid:11597413
|
Bernhard D et al. |
Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. |
2001 |
Cell Death Differ. |
pmid:11598799
|
Hirschler-Laszkiewicz I et al. |
The role of acetylation in rDNA transcription. |
2001 |
Nucleic Acids Res. |
pmid:11600700
|
Ullerås E et al. |
Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer. |
2001 |
Exp. Cell Res. |
pmid:11640883
|
Sachs LM et al. |
Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis. |
2001 |
Dev. Dyn. |
pmid:11668605
|
Laribee RN and Klemsz MJ |
Loss of PU.1 expression following inhibition of histone deacetylases. |
2001 |
J. Immunol. |
pmid:11673528
|
Rombouts K et al. |
Trichostatin A, lead compound for development of antifibrogenic drugs. |
2001 Jul-Sep |
Acta Gastroenterol. Belg. |
pmid:11680040
|
Biade S et al. |
Chemical agents that promote chromatin compaction radiosensitize tumour cells. |
2001 |
Int. J. Radiat. Biol. |
pmid:11682008
|
Mishra SK et al. |
Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells. |
2001 |
FEBS Lett. |
pmid:11682064
|
Sharma M and Sun Z |
5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription. |
2001 |
Mol. Endocrinol. |
pmid:11682623
|
Singal R et al. |
Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex. |
2002 |
J. Biol. Chem. |
pmid:11684679
|
Li J et al. |
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
2001 |
Mol. Cell. Biol. |
pmid:11689710
|
He LZ et al. |
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. |
2001 |
J. Clin. Invest. |
pmid:11696577
|
Amin HM et al. |
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). |
2001 |
Br. J. Haematol. |
pmid:11703323
|
Sanyal S et al. |
Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. |
2002 |
J. Biol. Chem. |
pmid:11705994
|
Pile LA et al. |
The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
2001 |
Cell. Mol. Life Sci. |
pmid:11706997
|
Galasinski SC et al. |
Global regulation of post-translational modifications on core histones. |
2002 |
J. Biol. Chem. |
pmid:11709551
|
Sachs LM et al. |
An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. |
2001 |
Int. J. Mol. Med. |
pmid:11712071
|
Lefevre P et al. |
Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
2001 |
Nucleic Acids Res. |
pmid:11713304
|
Hatama S et al. |
Isolation and sequencing of infectious clones of feline foamy virus and a human/feline foamy virus Env chimera. |
2001 |
J. Gen. Virol. |
pmid:11714976
|
Yoshioka H et al. |
A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting. |
2001 |
J. Hum. Genet. |
pmid:11721881
|
Stimson KM and Vertino PM |
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. |
2002 |
J. Biol. Chem. |
pmid:11733524
|
Cabral AL et al. |
Regulation of the cellular prion protein gene expression depends on chromatin conformation. |
2002 |
J. Biol. Chem. |
pmid:11739375
|
Park SH et al. |
Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. |
2002 |
J. Biol. Chem. |
pmid:11744689
|
Pujuguet P et al. |
Trichostatin A inhibits beta-casein expression in mammary epithelial cells. |
2001 |
J. Cell. Biochem. |
pmid:11746508
|
Matsusue K et al. |
Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor. |
2001 |
DNA Cell Biol. |
pmid:11749719
|
Lavelle D et al. |
Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. |
2001 |
Am. J. Hematol. |
pmid:11754398
|
Sourlingas TG et al. |
The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H1(0) synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study. |
2002 Jan-Mar |
Exp. Gerontol. |
pmid:11772521
|
Bordonaro M et al. |
Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. |
2002 |
Int. J. Cancer |
pmid:11774242
|
Kikuchi T et al. |
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. |
2002 |
Int. J. Cancer |
pmid:11774276
|
Ginjala V et al. |
Multiple cis elements within the Igf2/H19 insulator domain organize a distance-dependent silencer. A cautionary note. |
2002 |
J. Biol. Chem. |
pmid:11777900
|
Williams RJ |
Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis. |
2001 |
Expert Opin Investig Drugs |
pmid:11785457
|
Gurova KV et al. |
Expression of prostate specific antigen (PSA) is negatively regulated by p53. |
2002 |
Oncogene |
pmid:11791186
|
Suenaga M et al. |
Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells. |
2002 |
Int. J. Cancer |
pmid:11807787
|
Gong XQ and Li L |
Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
2002 |
J. Biol. Chem. |
pmid:11809751
|
Maeda Y et al. |
Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity. |
2002 |
Mol. Endocrinol. |
pmid:11818510
|
Gregory RI et al. |
Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells. |
2002 |
J. Biol. Chem. |
pmid:11821379
|
Lim Y et al. |
Trichostatin A-induced detransformation correlates with decreased focal adhesion kinase phosphorylation at tyrosine 861 in ras-transformed fibroblasts. |
2002 |
J. Biol. Chem. |
pmid:11821402
|
Wilson MA et al. |
The histone deacetylase inhibitor trichostatin A blocks progesterone receptor-mediated transactivation of the mouse mammary tumor virus promoter in vivo. |
2002 |
J. Biol. Chem. |
pmid:11821430
|
Deroanne CF et al. |
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. |
2002 |
Oncogene |
pmid:11821955
|
Sourlingas TG et al. |
Histone deacetylase inhibitors induce apoptosis in peripheral blood lymphocytes along with histone H4 acetylation and the expression of the linker histone variant, H1 degrees. |
2001 |
Eur. J. Cell Biol. |
pmid:11824792
|
Handumrongkul C et al. |
Distinct sets of cellular genes control the expression of transfected, nuclear-localized genes. |
2002 |
Mol. Ther. |
pmid:11829526
|
Herold C et al. |
The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. |
2002 |
J. Hepatol. |
pmid:11830335
|
Zhou DC et al. |
Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. |
2002 |
Blood |
pmid:11830487
|
Remiszewski SW et al. |
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates. |
2002 |
J. Med. Chem. |
pmid:11831887
|
Kiefer SM et al. |
Murine Sall1 represses transcription by recruiting a histone deacetylase complex. |
2002 |
J. Biol. Chem. |
pmid:11836251
|
Roddie PH et al. |
Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1. |
2002 |
Leukemia |
pmid:11840267
|
Valapour M et al. |
Histone deacetylation inhibits IL4 gene expression in T cells. |
2002 |
J. Allergy Clin. Immunol. |
pmid:11842291
|
McBurney MW et al. |
Evidence for repeat-induced gene silencing in cultured Mammalian cells: inactivation of tandem repeats of transfected genes. |
2002 |
Exp. Cell Res. |
pmid:11855851
|
Hou M et al. |
The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells. |
2002 |
Exp. Cell Res. |
pmid:11855854
|
Drewell RA et al. |
Methylation-dependent silencing at the H19 imprinting control region by MeCP2. |
2002 |
Nucleic Acids Res. |
pmid:11861904
|
Murphy JC et al. |
Control of cytomegalovirus lytic gene expression by histone acetylation. |
2002 |
EMBO J. |
pmid:11867539
|
Taniura S et al. |
Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells. |
2002 |
J. Biol. Chem. |
pmid:11877441
|
Heltweg B and Jung M |
A microplate reader-based nonisotopic histone deacetylase activity assay. |
2002 |
Anal. Biochem. |
pmid:11878795
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. |
2001 |
Brain Tumor Pathol |
pmid:11908866
|
Kamitani H et al. |
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. |
2002 |
Neuro-oncology |
pmid:11916500
|
Milutinovic S et al. |
Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification. |
2002 |
J. Biol. Chem. |
pmid:11929879
|
Chiocca S et al. |
Histone deacetylase 1 inactivation by an adenovirus early gene product. |
2002 |
Curr. Biol. |
pmid:11937030
|
Curradi M et al. |
Molecular mechanisms of gene silencing mediated by DNA methylation. |
2002 |
Mol. Cell. Biol. |
pmid:11940673
|
Koyama N et al. |
Differential effects of histone deacetylase inhibitors on interleukin-18 gene expression in myeloid cells. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11944905
|
Nair RR et al. |
Enhancement of transgene expression by combining glucocorticoids and anti-mitotic agents during transient transfection using DNA-cationic liposomes. |
2002 |
Mol. Ther. |
pmid:11945073
|
Chang TH and Szabo E |
Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. |
2002 |
Clin. Cancer Res. |
pmid:11948134
|
Ventura A et al. |
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. |
2002 |
J. Biol. Chem. |
pmid:11948181
|
Inoue H et al. |
Histone deacetylase inhibitors sensitize human colonic adenocarcinoma cell lines to TNF-related apoptosis inducing ligand-mediated apoptosis. |
2002 |
Int. J. Mol. Med. |
pmid:11956660
|
Mai A et al. |
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. |
2002 |
J. Med. Chem. |
pmid:11960489
|
Merezak C et al. |
Inhibition of histone deacetylases induces bovine leukemia virus expression in vitro and in vivo. |
2002 |
J. Virol. |
pmid:11967319
|
Nambiar MP et al. |
Effect of trichostatin A on human T cells resembles signaling abnormalities in T cells of patients with systemic lupus erythematosus: a new mechanism for TCR zeta chain deficiency and abnormal signaling. |
2002 |
J. Cell. Biochem. |
pmid:11967985
|
Fu M et al. |
Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. |
2002 |
Mol. Cell. Biol. |
pmid:11971970
|
Sirchia SM et al. |
Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. |
2002 |
Cancer Res. |
pmid:11980632
|
Qiu P and Li L |
Histone acetylation and recruitment of serum responsive factor and CREB-binding protein onto SM22 promoter during SM22 gene expression. |
2002 |
Circ. Res. |
pmid:11988486
|
Gradoville L et al. |
Protein kinase C-independent activation of the Epstein-Barr virus lytic cycle. |
2002 |
J. Virol. |
pmid:11991990
|
Uesato S et al. |
Novel histone deacetylase inhibitors: N-hydroxycarboxamides possessing a terminal bicyclic aryl group. |
2002 |
Bioorg. Med. Chem. Lett. |
pmid:11992774
|
Huang HC et al. |
Geldanamycin inhibits trichostatin A-induced cell death and histone H4 hyperacetylation in COS-7 cells. |
2002 |
Life Sci. |
pmid:12002521
|
Hoshimoto A et al. |
Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A. |
2002 |
Br. J. Pharmacol. |
pmid:12010777
|
Williams RS et al. |
A common mechanism of action for three mood-stabilizing drugs. |
2002 |
Nature |
pmid:12015604
|
Veilleux S and Boissonneault G |
Dynamics of reporter gene stimulation by HMG box proteins. |
2002 |
DNA Cell Biol. |
pmid:12015897
|
Nielsen J |
Combinatorial synthesis of natural products. |
2002 |
Curr Opin Chem Biol |
pmid:12023109
|
Mikkelsen IM et al. |
The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress. |
2002 |
Mol. Cell. Biochem. |
pmid:12030384
|
Iezzi S et al. |
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032356
|
Danbara M et al. |
DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines. |
2002 |
Mol. Immunol. |
pmid:12044782
|
Lin HM et al. |
Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors. |
2002 |
J. Biol. Chem. |
pmid:12048199
|
Katula KS et al. |
Cell cycle specific changes in the human cyclin B1 gene regulatory region as revealed by response to trichostatin A. |
2002 |
Arch. Biochem. Biophys. |
pmid:12054478
|
Wang XQ et al. |
Histone deacetylase inhibition results in decreased macrophage CD9 expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056820
|
Rahmani M et al. |
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. |
2002 |
Exp. Cell Res. |
pmid:12061815
|
Woo SH et al. |
Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors. |
2002 |
J. Med. Chem. |
pmid:12061890
|
Bharadwaj S and Prasad GL |
Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. |
2002 |
Cancer Lett. |
pmid:12065096
|
Ito K et al. |
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12070353
|
Toyooka S et al. |
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. |
2002 |
Oncogene |
pmid:12082623
|
Maehara K et al. |
Effects of histone acetylation on transcriptional regulation of manganese superoxide dismutase gene. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12083788
|
Chen Y et al. |
On the epigenetic regulation of the human reelin promoter. |
2002 |
Nucleic Acids Res. |
pmid:12087179
|
Zhang Y and Dufau ML |
Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex. |
2002 |
J. Biol. Chem. |
pmid:12091390
|
Weston AD et al. |
Requirement for RAR-mediated gene repression in skeletal progenitor differentiation. |
2002 |
J. Cell Biol. |
pmid:12105181
|