Ma J et al. |
Promoter hypermethylation and histone hypoacetylation contribute to pancreatic-duodenal homeobox 1 silencing in gastric cancer. |
2010 |
Carcinogenesis |
pmid:20622005
|
Oliveira CS et al. |
Effects of histone hyperacetylation on the preimplantation development of male and female bovine embryos. |
2010 |
Reprod. Fertil. Dev. |
pmid:20591338
|
Suo L et al. |
Changes in acetylation on lysine 12 of histone H4 (acH4K12) of murine oocytes during maternal aging may affect fertilization and subsequent embryo development. |
2010 |
Fertil. Steril. |
pmid:19285668
|
Xia J et al. |
Epigenetic modification of vomeronasal (V2r) precursor neurons by histone deacetylation. |
2010 |
Neuroscience |
pmid:20594945
|
Beedanagari SR et al. |
Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines. |
2010 |
Toxicol. Lett. |
pmid:20116417
|
Lu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, reduces lesion growth and hyperalgesia in experimentally induced endometriosis in mice. |
2010 |
Hum. Reprod. |
pmid:20118114
|
Davies GF et al. |
Troglitazone inhibits histone deacetylase activity in breast cancer cells. |
2010 |
Cancer Lett. |
pmid:19699029
|
Hajji N et al. |
Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. |
2010 |
Oncogene |
pmid:20118981
|
Hebbel RP et al. |
The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. |
2010 |
Blood |
pmid:20053759
|
Fu J et al. |
Discovery of 1H-benzo[d][1,2,3]triazol-1-yl 3,4,5-trimethoxybenzoate as a potential antiproliferative agent by inhibiting histone deacetylase. |
2010 |
Bioorg. Med. Chem. |
pmid:21067930
|
He R et al. |
Synthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agents. |
2010 |
J. Med. Chem. |
pmid:20055418
|
Nicodeme E et al. |
Suppression of inflammation by a synthetic histone mimic. |
2010 |
Nature |
pmid:21068722
|
Ajiro K et al. |
Reciprocal epigenetic modification of histone H2B occurs in chromatin during apoptosis in vitro and in vivo. |
2010 |
Cell Death Differ. |
pmid:20057502
|
Auzzas L et al. |
Non-natural macrocyclic inhibitors of histone deacetylases: design, synthesis, and activity. |
2010 |
J. Med. Chem. |
pmid:21073160
|
Song S et al. |
Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1. |
2010 |
Cardiovasc. Res. |
pmid:19633316
|
Eskeland R et al. |
Histone acetylation and the maintenance of chromatin compaction by Polycomb repressive complexes. |
2010 |
Cold Spring Harb. Symp. Quant. Biol. |
pmid:21502416
|
Wang QH et al. |
Opposite effects of Trichostatin A on activation of mast cells by different stimulants. |
2010 |
FEBS Lett. |
pmid:20371366
|
Simboeck E et al. |
A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors. |
2010 |
J. Biol. Chem. |
pmid:20952396
|
Robertson DM et al. |
C-terminal cleavage of DeltaNp63alpha is associated with TSA-induced apoptosis in immortalized corneal epithelial cells. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:20375332
|
Halili MA et al. |
Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. |
2010 |
J. Leukoc. Biol. |
pmid:20200406
|
Kitano A et al. |
Therapeutic potential of trichostatin A to control inflammatory and fibrogenic disorders of the ocular surface. |
2010 |
Mol. Vis. |
pmid:21203344
|
Higashiyama R et al. |
Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis. |
2010 |
Mod Rheumatol |
pmid:19784544
|
Law AY and Wong CK |
Stanniocalcin-2 is a HIF-1 target gene that promotes cell proliferation in hypoxia. |
2010 |
Exp. Cell Res. |
pmid:19786016
|
Pollack BP et al. |
Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. |
2009 May-Jun |
Photochem. Photobiol. |
pmid:19076306
|
Chen Z et al. |
BCL11A represses HBG transcription in K562 cells. |
2009 Mar-Apr |
Blood Cells Mol. Dis. |
pmid:19153051
|
Wang L et al. |
Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance. |
2009 Mar-Apr |
Immunol. Cell Biol. |
pmid:19172156
|
Allritz C et al. |
Endothelin-1 reverses the histone deacetylase inhibitor-induced increase in glial glutamate transporter transcription without affecting histone acetylation levels. |
2009 Jul-Aug |
Neurochem. Int. |
pmid:19428803
|
Wallace DM and Cotter TG |
Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina. |
2009 |
J. Neurosci. Res. |
pmid:18951482
|
Li M et al. |
Upregulation of human with-no-lysine kinase-4 gene expression by GATA-1 acetylation. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:18793746
|
Noro R et al. |
The anticancer effect of histone deacetylase inhibitors and combination with the cytotoxic agents in lung cancer cells: biological analyses for future clinical application. |
2009 |
J Nippon Med Sch |
pmid:19305113
|
Glenn DJ et al. |
Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2. |
2009 |
Hypertension |
pmid:19139378
|
Deng G et al. |
Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs. |
2009 |
Clin. Cancer Res. |
pmid:19223499
|
Sterthaus O et al. |
Evaluation of in vitro cultured rat oocytes, from different strains, by spindle morphology and maturation-promoting-factor activity combined with nuclear-transfer experiments. |
2009 |
Cloning Stem Cells |
pmid:19751114
|
Wang X et al. |
Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents. |
2009 |
Cancer Res. |
pmid:19752087
|
Hirata H et al. |
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. |
2009 |
Clin. Cancer Res. |
pmid:19755393
|
Chiou SK and Hoa N |
Up-regulation of GADD45alpha expression by NSAIDs leads to apoptotic and necrotic colon cancer cell deaths. |
2009 |
Apoptosis |
pmid:19757064
|
Vire B et al. |
Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions. |
2009 |
PLoS ONE |
pmid:19759901
|
Beebe LF et al. |
Cytochalasin B and trichostatin a treatment postactivation improves in vitro development of porcine somatic cell nuclear transfer embryos. |
2009 |
Cloning Stem Cells |
pmid:19780698
|
Olsen CA and Ghadiri MR |
Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides. |
2009 |
J. Med. Chem. |
pmid:19705846
|
Kee HJ and Kook H |
Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy. |
2009 |
J. Mol. Cell. Cardiol. |
pmid:19729022
|
Gao J et al. |
Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site. |
2009 |
Glia |
pmid:19062177
|
Noh EJ et al. |
An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19038231
|
Kong X et al. |
HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells. |
2009 |
J. Mol. Cell. Cardiol. |
pmid:19041327
|
Rossi M et al. |
Caspase cleavage of Itch in chronic lymphocytic leukemia cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19073138
|
Hostetter CL et al. |
Timing is everything: order of administration of 5-aza 2' deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity. |
2009 |
Cancer Lett. |
pmid:19013015
|
Heo H et al. |
Suppression of caspase-11 expression by histone deacetylase inhibitors. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19013432
|
Kishigami S and Wakayama T |
Somatic cell nuclear transfer in the mouse. |
2009 |
Methods Mol. Biol. |
pmid:19085136
|
Sibinga NE |
Stable protein, unstable plaque? |
2009 |
J. Mol. Cell. Cardiol. |
pmid:19101562
|
Niu F et al. |
Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-kappaB. |
2009 |
Brain Res. Bull. |
pmid:19103266
|
Santiago A et al. |
Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions. |
2009 |
Cell Cycle |
pmid:19106612
|
Kekatpure VD et al. |
HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. |
2009 |
J. Biol. Chem. |
pmid:19158084
|
Sutcliffe EL et al. |
Dynamic histone variant exchange accompanies gene induction in T cells. |
2009 |
Mol. Cell. Biol. |
pmid:19158270
|
Bagui TK et al. |
Inhibition of p27Kip1 gene transcription by mitogens. |
2009 |
Cell Cycle |
pmid:19158484
|
Wang X et al. |
Inhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes. |
2009 |
Growth Factors |
pmid:19107653
|
Cao Y et al. |
Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19966229
|
Trunzer M et al. |
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation. |
2009 |
J. Med. Chem. |
pmid:19108654
|
Smil DV et al. |
Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19111466
|
Bonetto A et al. |
Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. |
2009 |
Curr Cancer Drug Targets |
pmid:19508174
|
Chang J et al. |
The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons. |
2009 |
J. Cell. Sci. |
pmid:19509051
|
Nakajima S et al. |
Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231. |
2009 |
Oncol. Rep. |
pmid:19513516
|
Takaya T et al. |
MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells. |
2009 |
Circ. J. |
pmid:19521018
|
Sugimura S et al. |
Interspecies somatic cell nucleus transfer with porcine oocytes as recipients: A novel bioassay system for assessing the competence of canine somatic cells to develop into embryos. |
2009 |
Theriogenology |
pmid:19524287
|
Gregorie CJ et al. |
Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence. |
2009 |
J. Reprod. Immunol. |
pmid:19493573
|
Araki H et al. |
Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues. |
2009 |
Exp. Hematol. |
pmid:19501128
|
Pulukuri SM et al. |
Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer. |
2009 |
Oncogene |
pmid:19503093
|
Tian F et al. |
Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1. |
2009 |
J. Neurochem. |
pmid:19476549
|
Han SB and Lee JK |
Anti-inflammatory effect of Trichostatin-A on murine bone marrow-derived macrophages. |
2009 |
Arch. Pharm. Res. |
pmid:19407980
|
Lee JH et al. |
Structural and functional studies of the yeast class II Hda1 histone deacetylase complex. |
2009 |
J. Mol. Biol. |
pmid:19573535
|
Gan YH and Zhang S |
PTEN/AKT pathway involved in histone deacetylases inhibitor induced cell growth inhibition and apoptosis of oral squamous cell carcinoma cells. |
2009 |
Oral Oncol. |
pmid:19574087
|
Wang XX and Fu L |
[Recent advances in DNA demethylation in tumor therapy]. |
2009 |
Zhonghua Bing Li Xue Za Zhi |
pmid:19575888
|
Soriano FX et al. |
Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2. |
2009 |
Epigenetics |
pmid:19430206
|
Sawarkar R et al. |
Histone deacetylases regulate multicellular development in the social amoeba Dictyostelium discoideum. |
2009 |
J. Mol. Biol. |
pmid:19576222
|
Ma GD et al. |
[Role of histone deacetylase in inhibiting invasion of human gastric carcinoma cell line SGC-7901 by PPARgamma-mediated pathway]. |
2009 |
Ai Zheng |
pmid:19624894
|
Hong Z et al. |
Microarray study of mechanism of trichostatin a inducing apoptosis of Molt-4 cells. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:19662360
|
Dagtas AS et al. |
Histone deacetylase inhibitor uses p21(Cip1) to maintain anergy in CD4+ T cells. |
2009 |
Int. Immunopharmacol. |
pmid:19664724
|
Carambula SF et al. |
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19665989
|
Fujii K et al. |
Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells. |
2009 |
Cell Prolif. |
pmid:19614672
|
Pang M et al. |
Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. |
2009 |
Am. J. Physiol. Renal Physiol. |
pmid:19640900
|
Monks A et al. |
Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts. |
2009 |
Anticancer Drugs |
pmid:19606018
|
Hemmatazad H et al. |
Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis. |
2009 |
Arthritis Rheum. |
pmid:19404935
|
Gaymes TJ et al. |
Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes. |
2009 |
Haematologica |
pmid:19407318
|
Kim SN et al. |
Regulation of adipocyte differentiation by histone deacetylase inhibitors. |
2009 |
Arch. Pharm. Res. |
pmid:19407971
|
Hirose N et al. |
ATF-2 regulates lipopolysaccharide-induced transcription in macrophage cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19422799
|
Park SJ et al. |
Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway. |
2009 |
Biochem. Pharmacol. |
pmid:19426671
|
Piotrowska H and Jagodzinski PP |
Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells. |
2009 |
Arch. Med. Res. |
pmid:19427965
|
Yeh JR et al. |
Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. |
2009 |
Nat. Chem. Biol. |
pmid:19172146
|
Ai J et al. |
HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer. |
2009 |
Mol. Endocrinol. |
pmid:19855091
|
Codd R et al. |
Zn(II)-dependent histone deacetylase inhibitors: suberoylanilide hydroxamic acid and trichostatin A. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:18725319
|
von Dassow G et al. |
Action at a distance during cytokinesis. |
2009 |
J. Cell Biol. |
pmid:20008563
|
Kakihana M et al. |
Induction of E-cadherin in lung cancer and interaction with growth suppression by histone deacetylase inhibition. |
2009 |
J Thorac Oncol |
pmid:20009910
|
Peng DF et al. |
DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. |
2009 |
Gut |
pmid:18664505
|
O'Leary DA et al. |
Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. |
2009 |
PLoS ONE |
pmid:20020055
|
Lu MC et al. |
Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A. |
2009 |
Arch. Toxicol. |
pmid:18709356
|
Bonazzi VF et al. |
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. |
2009 |
Genes Chromosomes Cancer |
pmid:18803327
|
Meng CF et al. |
Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. |
2009 |
Oncol. Rep. |
pmid:19787243
|
Iljin K et al. |
High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth. |
2009 |
Clin. Cancer Res. |
pmid:19789329
|
Fraczek J et al. |
Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors. |
2009 |
Invest New Drugs |
pmid:18825314
|
Demircan B et al. |
Comparative epigenomics of human and mouse mammary tumors. |
2009 |
Genes Chromosomes Cancer |
pmid:18836996
|
Lee SH et al. |
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. |
2009 |
Oncogene |
pmid:18850007
|
Katsura T et al. |
The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells. |
2009 |
Cancer Gene Ther. |
pmid:18949013
|