Hsu DW et al. |
Dynamic acetylation of lysine-4-trimethylated histone H3 and H3 variant biology in a simple multicellular eukaryote. |
2012 |
Nucleic Acids Res. |
pmid:22600736
|
Zhang L et al. |
Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts. |
2012 |
J. Biol. Chem. |
pmid:23024362
|
Sancho-Pelluz J and Paquet-Durand F |
HDAC inhibition prevents Rd1 mouse photoreceptor degeneration. |
2012 |
Adv. Exp. Med. Biol. |
pmid:22183322
|
Chen H et al. |
LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma. |
2012 |
Cancer Lett. |
pmid:22743615
|
Qin ZX et al. |
[Effect of TSA and VPA treatment on long-tailed macaque (Macaca fascicularis)-pig interspecies somatic cell nuclear transfer]. |
2012 |
Yi Chuan |
pmid:22425953
|
Yoshida A et al. |
Aberrant spikelet and panicle1, encoding a TOPLESS-related transcriptional co-repressor, is involved in the regulation of meristem fate in rice. |
2012 |
Plant J. |
pmid:22136599
|
Usui T et al. |
HDAC4 mediates development of hypertension via vascular inflammation in spontaneous hypertensive rats. |
2012 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:22389387
|
Mostovich LA et al. |
Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors. |
2011 Sep-Oct |
Cell Adh Migr |
pmid:21975548
|
Stepanek I et al. |
Effects of 5-azacytidine and trichostatin A on dendritic cell maturation. |
2011 Oct-Dec |
J. Biol. Regul. Homeost. Agents |
pmid:22217985
|
Kee HJ et al. |
Trichostatin A prevents neointimal hyperplasia via activation of Krüppel like factor 4. |
2011 Nov-Dec |
Vascul. Pharmacol. |
pmid:21763782
|
Meng CF et al. |
DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells. |
2011 Nov-Dec |
Mol Med Rep |
pmid:21850374
|
Cowell IG et al. |
Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin. |
2011 Jan-Feb |
Nucleus |
pmid:21647300
|
Arany I et al. |
Epigenetic modifiers exert renal toxicity through induction of p66shc. |
2011 |
Anticancer Res. |
pmid:21965735
|
Sasaki Y et al. |
p53 negatively regulates the hepatoma growth factor HDGF. |
2011 |
Cancer Res. |
pmid:22006999
|
Aoyama K et al. |
Nuclear c-Abl-mediated tyrosine phosphorylation induces chromatin structural changes through histone modifications that include H4K16 hypoacetylation. |
2011 |
Exp. Cell Res. |
pmid:22001646
|
Jeon HG et al. |
Induction of caspase mediated apoptosis and down-regulation of nuclear factor-κB and Akt signaling are involved in the synergistic antitumor effect of gemcitabine and the histone deacetylase inhibitor trichostatin A in human bladder cancer cells. |
2011 |
J. Urol. |
pmid:21944112
|
Bo F et al. |
Effect of trichostatin A on transfected donor cells and subsequent development of porcine cloned embryos. |
2011 |
Zygote |
pmid:20569515
|
Hagiwara H et al. |
Histone deacetylase inhibitor trichostatin A enhances myogenesis by coordinating muscle regulatory factors and myogenic repressors. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:22019851
|
Jafari S et al. |
Epigenetic modification does not determine the time of POU5F1 transcription activation in cloned bovine embryos. |
2011 |
J. Assist. Reprod. Genet. |
pmid:22020531
|
Tseng AS et al. |
HDAC activity is required during Xenopus tail regeneration. |
2011 |
PLoS ONE |
pmid:22022609
|
Rajak H et al. |
2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21875796
|
He HM et al. |
[The effects of a histone deacetylase (HDAC) inhibitor on endotoxin-induced endothelial cell injury]. |
2011 |
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue |
pmid:22005560
|
Wang JP et al. |
Trichostatin A inhibits TGF-β1 induced in vitro chondrogenesis of hMSCs through Sp1 suppression. |
2011 |
Differentiation |
pmid:21074928
|
Oyer JA et al. |
Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation. |
2011 |
Mutat. Res. |
pmid:21035468
|
Pabba C et al. |
Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitors. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21109435
|
Vrzal R et al. |
Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia? |
2011 |
Toxicol. Lett. |
pmid:21115105
|
Coleman SL et al. |
Unsaturated fatty acids repress the expression of adipocyte fatty acid binding protein via the modulation of histone deacetylation in RAW 264.7 macrophages. |
2011 |
Eur J Nutr |
pmid:21046125
|
Marrazzo A et al. |
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells. |
2011 |
Eur J Med Chem |
pmid:21055848
|
Zhou S et al. |
Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. |
2011 |
Circ. Res. |
pmid:21778425
|
Jugová A et al. |
Effects of epigenetic-based anti-cancer drugs in leukaemia and multiple myeloma cells. |
2011 |
Cell Biol. Int. |
pmid:21635225
|
Wong CY et al. |
Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells. |
2011 |
J. Biol. Chem. |
pmid:21636851
|
Hayashi-Takanaka Y et al. |
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. |
2011 |
Nucleic Acids Res. |
pmid:21576221
|
Bouquet F et al. |
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia. |
2011 |
J. Cell. Sci. |
pmid:21576354
|
Hawk JD et al. |
Post-training intrahippocampal inhibition of class I histone deacetylases enhances long-term object-location memory. |
2011 |
Learn. Mem. |
pmid:21576516
|
Dong X et al. |
Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells. |
2011 |
Endocr. Relat. Cancer |
pmid:21367844
|
Zhu QY et al. |
C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo. |
2011 |
Cell Death Dis |
pmid:21368888
|
Hsu YF et al. |
p53 in trichostatin A induced C6 glioma cell death. |
2011 |
Biochim. Biophys. Acta |
pmid:21376104
|
Ryhänen T et al. |
Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells. |
2011 |
J. Biomed. Biotechnol. |
pmid:20981255
|
Briggs B et al. |
Photosensitization by iodinated DNA minor groove binding ligands: Evaluation of DNA double-strand break induction and repair. |
2011 |
J. Photochem. Photobiol. B, Biol. |
pmid:21440453
|
Seitz V et al. |
Classical Hodgkin's lymphoma shows epigenetic features of abortive plasma cell differentiation. |
2011 |
Haematologica |
pmid:21393330
|
Agudelo M et al. |
Effects of alcohol on histone deacetylase 2 (HDAC2) and the neuroprotective role of trichostatin A (TSA). |
2011 |
Alcohol. Clin. Exp. Res. |
pmid:21447001
|
Zhang Y et al. |
ERK1/2 activation plays important roles in the opposite effects of Trichostatin A in non-cancer and cancer cells. |
2011 |
Toxicon |
pmid:21419152
|
WEI Q et al. |
[Trichostatin A inhibits the activation of CD(4)(+) T cells by suppressing CD(28) expression in mice]. |
2011 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:21421475
|
Xiao J et al. |
Discovery, synthesis, and biological evaluation of novel SMN protein modulators. |
2011 |
J. Med. Chem. |
pmid:21819082
|
Min XJ et al. |
Dysfunction of volume-sensitive chloride channels contributes to cisplatin resistance in human lung adenocarcinoma cells. |
2011 |
Exp. Biol. Med. (Maywood) |
pmid:21454376
|
Belakavadi M et al. |
Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21458529
|
Dávalos-Salas M et al. |
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. |
2011 |
BMC Cancer |
pmid:21663659
|
El-Serafi AT et al. |
Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A. |
2011 |
Differentiation |
pmid:20970916
|
Zelko IN et al. |
Histone acetylation regulates the cell-specific and interferon-γ-inducible expression of extracellular superoxide dismutase in human pulmonary arteries. |
2011 |
Am. J. Respir. Cell Mol. Biol. |
pmid:21493784
|
Zhang FQ et al. |
Cell-cycle-dependent variations in the FTIR spectroscopy of HeLa cells treated with trichostatin A. |
2011 |
Guang Pu Xue Yu Guang Pu Fen Xi |
pmid:22007388
|
da Costa Prando E et al. |
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines. |
2011 |
Epigenetics |
pmid:22139571
|
Nagamine MK et al. |
In vitro inhibitory effect of trichostatin A on canine grade 3 mast cell tumor. |
2011 |
Vet. Res. Commun. |
pmid:21472452
|
Kretzner L et al. |
Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels. |
2011 |
Cancer Res. |
pmid:21502403
|
Maruoka H et al. |
Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons. |
2011 |
J. Biochem. |
pmid:21908547
|
Poplineau M et al. |
Raman microspectroscopy detects epigenetic modifications in living Jurkat leukemic cells. |
2011 |
Epigenomics |
pmid:22126296
|
Qiu GH et al. |
Recognition and suppression of transfected plasmids by protein ZNF511-PRAP1, a potential molecular barrier to transgene expression. |
2011 |
Mol. Ther. |
pmid:21540836
|
Kong Q et al. |
Effect of trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells. |
2011 |
Mol. Cell. Biochem. |
pmid:21541675
|
Wang QS et al. |
[Silence mechanism of WT1 gene in leukemic cell line U937]. |
2011 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:22040952
|
Park JW et al. |
Microbial transformation of trichostatin A to 2,3-dihydrotrichostatin A. |
2011 |
J. Nat. Prod. |
pmid:21504214
|
Matoba S et al. |
RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22065773
|
Bolleyn J et al. |
Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes. |
2011 |
Toxicol In Vitro |
pmid:21513791
|
Rajasingh J et al. |
Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells. |
2011 |
PLoS ONE |
pmid:21799893
|
Ramsey MR et al. |
Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma. |
2011 |
Cancer Res. |
pmid:21527555
|
Klawitter M et al. |
Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration. |
2011 |
J Negat Results Biomed |
pmid:21801383
|
Nishikata I et al. |
Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation. |
2011 |
Oncogene |
pmid:21516122
|
Tong Y et al. |
PTTG1 attenuates drug-induced cellular senescence. |
2011 |
PLoS ONE |
pmid:21858218
|
Crump NT et al. |
Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21518915
|
Bui HT et al. |
Histone deacetylase inhibition improves activation of ribosomal RNA genes and embryonic nucleolar reprogramming in cloned mouse embryos. |
2011 |
Biol. Reprod. |
pmid:21753193
|
Biermann J et al. |
Histone deacetylase inhibitors sodium butyrate and valproic acid delay spontaneous cell death in purified rat retinal ganglion cells. |
2011 |
Mol. Vis. |
pmid:21311741
|
Fortson WS et al. |
Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. |
2011 |
Int. J. Oncol. |
pmid:21519790
|
Huang KT et al. |
Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer. |
2011 |
Breast Cancer Res. Treat. |
pmid:21755341
|
Inoue H et al. |
Analysis of expression and structure of the rat GH-secretagogue/ghrelin receptor (Ghsr) gene: roles of epigenetic modifications in transcriptional regulation. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21756973
|
Watanabe Y and Tanaka M |
p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate. |
2011 |
J. Cell. Sci. |
pmid:21771882
|
Li S et al. |
Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis. |
2011 |
Mol. Cancer |
pmid:21314984
|
Fu S et al. |
Involvement of histone acetylation of Sox17 and Foxa2 promoters during mouse definitive endoderm differentiation revealed by microRNA profiling. |
2011 |
PLoS ONE |
pmid:22132182
|
Atanackovic D et al. |
Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia. |
2011 |
Am. J. Hematol. |
pmid:21898529
|
Paterson S et al. |
Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells. |
2011 |
Drug Metab. Dispos. |
pmid:20870783
|
Wang JP et al. |
Recapitulation of fibromatosis nodule by multipotential stem cells in immunodeficient mice. |
2011 |
PLoS ONE |
pmid:21901157
|
Nakaya Y et al. |
Epigenetic regulation on the 5'-proximal CpG island of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B. |
2011 |
Microbes Infect. |
pmid:20951222
|
Robers MB et al. |
Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology. |
2011 |
Mol Biosyst |
pmid:20931131
|
Hsu YF et al. |
MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide. |
2011 |
Biochim. Biophys. Acta |
pmid:21911040
|
Crandall JE et al. |
Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex. |
2011 |
J. Neurochem. |
pmid:21895658
|
Bogaard HJ et al. |
Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats. |
2011 |
Am. J. Respir. Crit. Care Med. |
pmid:21297075
|
Jafarpour F et al. |
Somatic cell-induced hyperacetylation, but not hypomethylation, positively and reversibly affects the efficiency of in vitro cloned blastocyst production in cattle. |
2011 |
Cell Reprogram |
pmid:21919704
|
Furumai R et al. |
Histone deacetylase inhibitors block nuclear factor-κB-dependent transcription by interfering with RNA polymerase II recruitment. |
2011 |
Cancer Sci. |
pmid:21299717
|
Chen S et al. |
[Effect of trichostatin alone and combination with imatinb on the proliferation and apoptosis of the K562R cells]. |
2011 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:21937807
|
Cai HH et al. |
Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines. |
2011 |
HBPD INT |
pmid:21269942
|
Chen WP et al. |
Trichostatin A inhibits expression of cathepsins in experimental osteoarthritis. |
2011 |
Rheumatol. Int. |
pmid:20390279
|
Nandakumar V et al. |
(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells. |
2011 |
Carcinogenesis |
pmid:21209038
|
Kang H and Roh S |
Extended exposure to trichostatin A after activation alters the expression of genes important for early development in nuclear transfer murine embryos. |
2011 |
J. Vet. Med. Sci. |
pmid:21187677
|
Mitmaker EJ et al. |
Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors. |
2011 |
Surgery |
pmid:21193210
|
Liao M et al. |
Coactivator function of positive cofactor 4 (PC4) in Sp1-directed luteinizing hormone receptor (LHR) gene transcription. |
2011 |
J. Biol. Chem. |
pmid:21193408
|
Erb TM et al. |
Paracrine and epigenetic control of trophectoderm differentiation from human embryonic stem cells: the role of bone morphogenic protein 4 and histone deacetylases. |
2011 |
Stem Cells Dev. |
pmid:21204619
|
Farinas B and Mas P |
Functional implication of the MYB transcription factor RVE8/LCL5 in the circadian control of histone acetylation. |
2011 |
Plant J. |
pmid:21205033
|
Host L et al. |
Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition. |
2011 |
J. Psychopharmacol. (Oxford) |
pmid:19939859
|
Muralidhar SA et al. |
Histone deacetylase 9 activates gamma-globin gene expression in primary erythroid cells. |
2011 |
J. Biol. Chem. |
pmid:21078662
|
Chakravarty G et al. |
Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment. |
2011 |
Cancer Biol. Ther. |
pmid:21084857
|
Meng Y et al. |
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. |
2011 |
Dig. Dis. Sci. |
pmid:21567192
|
Puppin C et al. |
Histone deacetylase inhibitors induce thymidine phosphorylase expression in cultured breast cancer cell lines. |
2011 |
Oncol. Rep. |
pmid:21617864
|
Shu G et al. |
Zac1 is a histone acetylation-regulated NF-κB suppressor that mediates histone deacetylase inhibitor-induced apoptosis. |
2011 |
Cell Death Differ. |
pmid:21546906
|