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2002 |
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Cancer Cell |
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Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. |
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A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. |
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Biochemistry |
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Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
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Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. |
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Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
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2001 Jul-Sep |
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