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BioTechniques |
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Long-term hydroxytamoxifen treatment of an MCF-7-derived breast cancer cell line irreversibly inhibits the expression of estrogenic genes through chromatin remodeling. |
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Cancer Res. |
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The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter. |
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A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest. |
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Proc. Natl. Acad. Sci. U.S.A. |
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IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a. |
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Cytokine |
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A histone deacetylase inhibitor potentiates estrogen receptor activation of a stably integrated vitellogenin promoter in HepG2 cells. |
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Endocrinology |
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Human Slug is a repressor that localizes to sites of active transcription. |
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Cancer Res. |
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Promoter specific sensitivity to inhibition of histone deacetylases: implications for hormonal gene control, cellular differentiation and cancer. |
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The mouse tumor cell lines EL4 and RMA display mosaic expression of NK-related and certain other surface molecules and appear to have a common origin. |
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Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all-trans retinoic acid. |
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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. |
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Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. |
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Cell |
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