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Anticancer Res. |
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Int. J. Cancer |
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Histone deacetylase inhibitor trichostatin A enhances myogenesis by coordinating muscle regulatory factors and myogenic repressors. |
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Biochem. Biophys. Res. Commun. |
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J. Assist. Reprod. Genet. |
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HDAC activity is required during Xenopus tail regeneration. |
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PLoS ONE |
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2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors. |
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Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. |
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J Thorac Oncol |
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SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. |
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BMC Cancer |
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Structure-based optimization of click-based histone deacetylase inhibitors. |
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Eur J Med Chem |
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The histone acetyltransferase p300 promotes intrinsic axonal regeneration. |
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Brain |
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Lipids |
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Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis. |
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Exp. Neurol. |
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Epigenetic inactivation of PCDH10 in human prostate cancer cell lines. |
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Cell Biol. Int. |
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Neurochem. Int. |
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Cancer Invest. |
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DeltaNp63, a target of DEC1 and histone deacetylase 2, modulates the efficacy of histone deacetylase inhibitors in growth suppression and keratinocyte differentiation. |
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PLoS ONE |
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Mod. Pathol. |
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Int. J. Oncol. |
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Human parthenogenetic stem cells produce enriched populations of definitive endoderm cells after trichostatin A pretreatment. |
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Differentiation |
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Enrichment of Nur77 mediated by retinoic acid receptor β leads to apoptosis of human hepatocellular carcinoma cells induced by fenretinide and histone deacetylase inhibitors. |
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Hepatology |
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Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice. |
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Immunol. Cell Biol. |
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Chromatin-modifying agents promote the ex vivo production of functional human erythroid progenitor cells. |
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Blood |
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The CKH2/PKL chromatin remodeling factor negatively regulates cytokinin responses in Arabidopsis calli. |
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Plant Cell Physiol. |
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Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300. |
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J Toxicol Sci |
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Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. |
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Apoptosis |
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Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize. |
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PLoS ONE |
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Isolation of mesenchymal stem cells from human ligamentum flavum: implicating etiology of ligamentum flavum hypertrophy. |
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Spine |
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Trichostatin A promotes the development of bovine somatic cell nuclear transfer embryos. |
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J. Reprod. Dev. |
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Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. |
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PLoS ONE |
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Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. |
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Oncogene |
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Genomic DNA hypomethylation by histone deacetylase inhibition implicates DNMT1 nuclear dynamics. |
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Mol. Cell. Biol. |
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TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers. |
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Epigenetics |
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PLoS ONE |
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Pluripotency maintenance in mouse somatic cell nuclear transfer embryos and its improvement by treatment with the histone deacetylase inhibitor TSA. |
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Cell Reprogram |
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Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer. |
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Am. J. Pathol. |
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In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription. |
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Cell Oncol (Dordr) |
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Histone deacetylation directs DNA methylation in survivin gene silencing. |
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Biochem. Biophys. Res. Commun. |
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Trichostatin A modified histone covalent pattern and enhanced expression of pluripotent genes in interspecies black-footed cat cloned embryos but did not improve in vitro and in vivo viability. |
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Cell Reprogram |
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Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors. |
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Bioorg. Med. Chem. |
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Histone deacetylase inhibitors augment doxorubicin-induced DNA damage in cardiomyocytes. |
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Cell. Mol. Life Sci. |
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Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice. |
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Arthritis Res. Ther. |
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Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. |
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J Thorac Oncol |
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