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Chromatin structure and expression of the AMPA receptor subunit Glur2 in human glioma cells: major regulatory role of REST and Sp1. |
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Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells. |
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PLoS ONE |
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Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors. |
2011 Sep-Oct |
Cell Adh Migr |
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2011 Oct-Dec |
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2011 Nov-Dec |
Mol Med Rep |
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Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin. |
2011 Jan-Feb |
Nucleus |
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The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation. |
2011 |
PLoS ONE |
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Elucidating the mechanism of regulation of transforming growth factor β Type II receptor expression in human lung cancer cell lines. |
2011 |
Neoplasia |
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Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ΔF508-CFTR. |
2011 |
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Panhistone deacetylase inhibitors inhibit proinflammatory signaling pathways to ameliorate interleukin-18-induced cardiac hypertrophy. |
2011 |
Physiol. Genomics |
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Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. |
2011 |
Int. J. Cancer |
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2011 |
Int. J. Cancer |
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Circ. Res. |
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2011 |
PLoS ONE |
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2011 |
Am. J. Respir. Cell Mol. Biol. |
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Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma. |
2011 |
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HDAC inhibitor trichostatin A suppresses osteoclastogenesis by upregulating the expression of C/EBP-β and MKP-1. |
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Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. |
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J Thorac Oncol |
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SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. |
2011 |
BMC Cancer |
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Structure-based optimization of click-based histone deacetylase inhibitors. |
2011 |
Eur J Med Chem |
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2011 |
J. Biol. Rhythms |
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The histone acetyltransferase p300 promotes intrinsic axonal regeneration. |
2011 |
Brain |
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Mifepristone treatment results in differential regulation of glycerolipid biosynthesis in baby hamster kidney cells expressing a mifepristone-inducible ABCA1. |
2011 |
Lipids |
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Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis. |
2011 |
Exp. Neurol. |
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3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements. |
2011 |
PLoS ONE |
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2011 |
Org. Lett. |
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Asymmetric leaves2 and Elongator, a histone acetyltransferase complex, mediate the establishment of polarity in leaves of Arabidopsis thaliana. |
2011 |
Plant Cell Physiol. |
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Histone modifications on the adrenergic induction of type II deiodinase in rat pinealocytes. |
2011 |
Mol. Cell. Endocrinol. |
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ABA treatment of germinating maize seeds induces VP1 gene expression and selective promoter-associated histone acetylation. |
2011 |
Physiol Plant |
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2011 |
Curr. HIV Res. |
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Effects of epigenetic-based anti-cancer drugs in leukaemia and multiple myeloma cells. |
2011 |
Cell Biol. Int. |
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Epigenetic inactivation of PCDH10 in human prostate cancer cell lines. |
2011 |
Cell Biol. Int. |
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HIV-1 Tat upregulates expression of histone deacetylase-2 (HDAC2) in human neurons: implication for HIV-associated neurocognitive disorder (HAND). |
2011 |
Neurochem. Int. |
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Cancer Invest. |
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Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis. |
2011 |
PLoS ONE |
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Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. |
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Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells. |
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Human parthenogenetic stem cells produce enriched populations of definitive endoderm cells after trichostatin A pretreatment. |
2011 |
Differentiation |
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Enrichment of Nur77 mediated by retinoic acid receptor β leads to apoptosis of human hepatocellular carcinoma cells induced by fenretinide and histone deacetylase inhibitors. |
2011 |
Hepatology |
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Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice. |
2011 |
Immunol. Cell Biol. |
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Chromatin-modifying agents promote the ex vivo production of functional human erythroid progenitor cells. |
2011 |
Blood |
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2011 |
J. Cell. Physiol. |
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The CKH2/PKL chromatin remodeling factor negatively regulates cytokinin responses in Arabidopsis calli. |
2011 |
Plant Cell Physiol. |
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2011 |
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Comparison of potency between histone deacetylase inhibitors trichostatin A and valproic acid on enhancing in vitro development of porcine somatic cell nuclear transfer embryos. |
2011 |
In Vitro Cell. Dev. Biol. Anim. |
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Mol. Cell. Biochem. |
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EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression. |
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Mol. Cancer Res. |
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[Study of RASSF1A expression and promoter demethylation in Hep-2 cell line]. |
2011 |
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Trichostatin A modulates apoptotic-related gene expression and improves embryo viability in cloned bovine embryos. |
2011 |
Cell Reprogram |
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Design, synthesis and biological evaluation of hydroxamic acid derivatives as potential high density lipoprotein (HDL) receptor CLA-1 up-regulating agents. |
2011 |
Molecules |
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Histone deacetylase inhibitors demonstrate significant preclinical activity as single agents, and in combination with bortezomib in Waldenström's macroglobulinemia. |
2011 |
Clin Lymphoma Myeloma Leuk |
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[TSA improve transgenic porcine cloned embryo development and transgene expression]. |
2011 |
Yi Chuan |
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Dysfunction of volume-sensitive chloride channels contributes to cisplatin resistance in human lung adenocarcinoma cells. |
2011 |
Exp. Biol. Med. (Maywood) |
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Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events. |
2011 |
Mol. Cell. Endocrinol. |
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Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins. |
2011 |
J. Cell. Biochem. |
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Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300. |
2011 |
J Toxicol Sci |
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Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. |
2011 |
Apoptosis |
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Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize. |
2011 |
PLoS ONE |
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Isolation of mesenchymal stem cells from human ligamentum flavum: implicating etiology of ligamentum flavum hypertrophy. |
2011 |
Spine |
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Trichostatin A promotes the development of bovine somatic cell nuclear transfer embryos. |
2011 |
J. Reprod. Dev. |
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Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. |
2011 |
PLoS ONE |
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Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. |
2011 |
Oncogene |
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Genomic DNA hypomethylation by histone deacetylase inhibition implicates DNMT1 nuclear dynamics. |
2011 |
Mol. Cell. Biol. |
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TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers. |
2011 |
Epigenetics |
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Treatment with a histone deacetylase inhibitor after nuclear transfer improves the preimplantation development of cloned bovine embryos. |
2011 |
J. Reprod. Dev. |
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Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. |
2011 |
Epigenetics |
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γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines. |
2011 |
Int. J. Radiat. Biol. |
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Trichostatin A restores Apaf-1 function in chemoresistant ovarian cancer cells. |
2011 |
Cancer |
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Epigenetic silencing of somatostatin in gastric cancer. |
2011 |
Dig. Dis. Sci. |
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Latent HIV in primary T lymphocytes is unresponsive to histone deacetylase inhibitors. |
2011 |
Virol. J. |
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Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression. |
2011 |
Bioorg. Med. Chem. Lett. |
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Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia. |
2011 |
Am. J. Hematol. |
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Pluripotency maintenance in mouse somatic cell nuclear transfer embryos and its improvement by treatment with the histone deacetylase inhibitor TSA. |
2011 |
Cell Reprogram |
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Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel. |
2011 |
BMC Cancer |
pmid:21244707
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Nakamura J et al. |
Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer. |
2011 |
Am. J. Pathol. |
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In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription. |
2011 |
Cell Oncol (Dordr) |
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Cutting edge: tubulin α functions as an adaptor in NFAT-importin β interaction. |
2011 |
J. Immunol. |
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Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy. |
2011 |
Cancer |
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Histone deacetylation directs DNA methylation in survivin gene silencing. |
2011 |
Biochem. Biophys. Res. Commun. |
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Nucleophosmin delocalization in thyroid tumour cells. |
2011 |
Endocr. Pathol. |
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Trichostatin A modified histone covalent pattern and enhanced expression of pluripotent genes in interspecies black-footed cat cloned embryos but did not improve in vitro and in vivo viability. |
2011 |
Cell Reprogram |
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Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors. |
2011 |
Bioorg. Med. Chem. |
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Histonedeacetylase inhibitor Oxamflatin increase HIV-1 transcription by inducing histone modification in latently infected cells. |
2011 |
Mol. Biol. Rep. |
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Point mutated caveolin-3 form (P104L) impairs myoblast differentiation via Akt and p38 signalling reduction, leading to an immature cell signature. |
2011 |
Biochim. Biophys. Acta |
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Histone deacetylase inhibitors control the transcription and alternative splicing of prohibitin in thyroid tumor cells. |
2011 |
Oncol. Rep. |
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Interplay between PKCδ and Sp1 on histone deacetylase inhibitor-mediated Epstein-Barr virus reactivation. |
2011 |
J. Virol. |
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(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells. |
2011 |
Carcinogenesis |
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Kang H and Roh S |
Extended exposure to trichostatin A after activation alters the expression of genes important for early development in nuclear transfer murine embryos. |
2011 |
J. Vet. Med. Sci. |
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Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice. |
2011 |
Arthritis Res. Ther. |
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Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. |
2011 |
J Thorac Oncol |
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