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Identification and functional characterization of the promoter of the mouse sodium-activated sodium channel Na(x) gene (Scn7a). |
2009 |
J. Neurosci. Res. |
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Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. |
2009 |
Biochem. Biophys. Res. Commun. |
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AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. |
2009 |
PLoS ONE |
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Schistosoma mansoni: developmental arrest of miracidia treated with histone deacetylase inhibitors. |
2009 |
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Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. |
2009 |
Blood |
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Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. |
2009 |
Eur. J. Pharmacol. |
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Recent advances in the development of polyamine analogues as antitumor agents. |
2009 |
J. Med. Chem. |
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Epigenetic hierarchy governing Nestin expression. |
2009 |
Stem Cells |
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Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. |
2009 |
Carcinogenesis |
pmid:19329758
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Åuczak MW and JagodziÅ„ski PP |
Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
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Ma X et al. |
Identification of LIV1, a putative zinc transporter gene responsible for HDACi-induced apoptosis, using a functional gene screen approach. |
2009 |
Mol. Cancer Ther. |
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Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
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IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin. |
2009 |
Int. J. Biochem. Cell Biol. |
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Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos. |
2009 |
Blood |
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Regulatory roles for histone deacetylation in IL-1beta-induced nitric oxide release in pancreatic beta-cells. |
2008 Sep-Oct |
J. Cell. Mol. Med. |
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[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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Kir'ianov GI et al. |
[Nucleosome positioning within neomycinphosphotransferase gene (NPTII) on yeast plasmid in repressed and active state]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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Miyoshi M et al. |
Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells. |
2008 Nov-Dec |
Nutrition |
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Nishikiori N et al. |
Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. |
2008 May-Jun |
Jpn. J. Ophthalmol. |
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In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. |
2008 Mar-Apr |
J. Androl. |
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To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A. |
2008 Jul-Sep |
Eur J Histochem |
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Kovács P and Csaba G |
The effect of histone deacetylase inhibitor trichostatin A (TSA) on the incorporation of 32P (Pi) and 3H-palmitic acid into the phospholipids of Tetrahymena. |
2008 Jan-Feb |
Cell Biochem. Funct. |
pmid:17191269
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Dowling DP et al. |
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. |
2008 |
Biochemistry |
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[The role of DNA methylation and histone modifications in structural maintainance of heterochromatin domains (chromocenters)]. |
2008 |
Tsitologiia |
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Histone deacetylase inhibitors blocked activation and caused senescence of corneal stromal cells. |
2008 |
Mol. Vis. |
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[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP]. |
2008 |
Ai Zheng |
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Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. |
2008 |
Nutr Res |
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Domingo-Domènech J et al. |
Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. |
2008 |
Breast Cancer Res. Treat. |
pmid:18064564
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Hajji N et al. |
Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. |
2008 |
Oncogene |
pmid:18071312
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Walton TJ et al. |
DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines. |
2008 |
Prostate |
pmid:18092350
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Arany I et al. |
Restoration of CREB function ameliorates cisplatin cytotoxicity in renal tubular cells. |
2008 |
Am. J. Physiol. Renal Physiol. |
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Jiemjit A et al. |
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. |
2008 |
Oncogene |
pmid:18223691
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Nasu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model. |
2008 |
Osteoarthr. Cartil. |
pmid:18226559
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Lim HG et al. |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. |
2008 |
Mol. Ther. |
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Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. |
2008 |
Stem Cells |
pmid:18203677
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Spatial distribution of histone methylation during MHC class II expression. |
2008 |
Mol. Immunol. |
pmid:17850872
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Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies. |
2008 |
Eur J Med Chem |
pmid:17698257
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Byers J and Eichinger D |
Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner. |
2008 |
Int. J. Parasitol. |
pmid:17706222
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Pan J et al. |
TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. |
2008 |
Mol. Cancer Res. |
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Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation. |
2008 |
BMC Dev. Biol. |
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Dalgard CL et al. |
Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma. |
2008 |
Clin. Cancer Res. |
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Lin W et al. |
Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40. |
2008 |
Genes Cells |
pmid:18298800
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Fan J et al. |
ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. |
2008 |
J. Cancer Res. Clin. Oncol. |
pmid:18264725
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Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos. |
2008 |
Dev. Dyn. |
pmid:18265023
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Sasaki K et al. |
Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera. |
2008 |
Cancer Sci. |
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Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. |
2008 |
Genes Dev. |
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Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells. |
2008 |
Oncogene |
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APE1/Ref-1 regulates PTEN expression mediated by Egr-1. |
2008 |
Free Radic. Res. |
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CCAAT box is required for the induction of human thrombospondin-1 gene by trichostatin A. |
2008 |
J. Cell. Biochem. |
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Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. |
2008 |
Exp. Mol. Pathol. |
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Nakamura C et al. |
Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells. |
2008 |
Rheumatology (Oxford) |
pmid:18281366
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Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. |
2008 |
Neuro-oncology |
pmid:18445700
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Yu WP et al. |
Induction of ID1 expression and apoptosis by the histone deacetylase inhibitor (trichostatin A) in human acute myeloid leukaemic cells. |
2008 |
Cell Prolif. |
pmid:18211287
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Jensen TJ et al. |
Epigenetic remodeling during arsenical-induced malignant transformation. |
2008 |
Carcinogenesis |
pmid:18448484
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Kikuno N et al. |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. |
2008 |
Int. J. Cancer |
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Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. |
2008 |
Microbiology (Reading, Engl.) |
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Zhang HJ et al. |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. |
2008 |
Placenta |
pmid:18440631
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Liu Z et al. |
Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. |
2008 |
Oncol. Rep. |
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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
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Modulation of transcription parameters in glucocorticoid receptor-mediated repression. |
2008 |
Mol. Cell. Endocrinol. |
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Hishikawa K and Fujita T |
[Kidney regeneration update]. |
2008 |
Nippon Rinsho |
pmid:18464514
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Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. |
2008 |
Exp. Cell Res. |
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Chen CJ et al. |
Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18590721
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Marengo E et al. |
Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. |
2008 |
J. Proteome Res. |
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Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18544619
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Gaviraghi M et al. |
Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene. |
2008 |
BMC Mol. Biol. |
pmid:18549468
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Mühlethaler-Mottet A et al. |
Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells. |
2008 |
Mol. Cancer |
pmid:18549473
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Kim B et al. |
Clinically relevant concentrations of valproic acid modulate melatonin MT(1) receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18550052
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Rebbaa A et al. |
Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent. |
2008 |
Angiogenesis |
pmid:18386142
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Henkens T et al. |
Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes. |
2008 |
Toxicol. Lett. |
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[Effect of trichostatin A on proliferation and interleukin-2 expression of mouse T cells in mixed lymphocyte culture]. |
2008 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:18359716
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Hämäläinen M et al. |
Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors. |
2008 |
Pulm Pharmacol Ther |
pmid:17913526
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Svechnikova I et al. |
HDAC inhibitors effectively induce cell type-specific differentiation in human glioblastoma cell lines of different origin. |
2008 |
Int. J. Oncol. |
pmid:18360709
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Mukherjee P et al. |
Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy. |
2008 |
Bioorg. Med. Chem. |
pmid:18362073
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Pryzbylkowski P et al. |
Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. |
2008 |
Breast Cancer Res. Treat. |
pmid:17891453
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Brown SL et al. |
Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice. |
2008 |
Radiat. Res. |
pmid:18363436
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Vrbova G |
Spinal muscular atrophy: motoneurone or muscle disease? |
2008 |
Neuromuscul. Disord. |
pmid:18365338
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Iager AE et al. |
Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos. |
2008 |
Cloning Stem Cells |
pmid:18419249
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Liu TC et al. |
Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. |
2008 |
Mol. Ther. |
pmid:18388912
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Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. |
2008 |
J. Biol. Chem. |
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The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. |
2008 |
J. Autoimmun. |
pmid:18650065
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Pluemsampant S et al. |
Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. |
2008 |
Int. J. Cancer |
pmid:17935135
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Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. |
2008 |
Exp. Cell Res. |
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Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. |
2008 |
J. Leukoc. Biol. |
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[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. |
2008 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:18718068
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Gastric cancer cell lines induced by trichostatin A. |
2008 |
World J. Gastroenterol. |
pmid:18720545
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Duan H et al. |
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
2008 |
Oncogene |
pmid:18695675
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Ding X et al. |
Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. |
2008 |
Theriogenology |
pmid:18556056
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Jia J and Chen J |
Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death. |
2008 |
Pharmazie |
pmid:18557424
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Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition. |
2008 |
Ann. Neurol. |
pmid:18661558
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Yu J et al. |
Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. |
2008 |
Hepatology |
pmid:18666234
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Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18706393
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Liu F et al. |
Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18926829
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Gu Z et al. |
Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas. |
2008 |
Genes Genet. Syst. |
pmid:18931460
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Yoshioka H et al. |
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
2008 |
J. Biol. Chem. |
pmid:18801729
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Wu Y and Guo SW |
Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells. |
2008 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:17376583
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Jin B et al. |
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. |
2008 |
Hum. Mol. Genet. |
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Gan Y et al. |
Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. |
2008 |
Biochem. Biophys. Res. Commun. |
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Lee EJ et al. |
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
2008 |
Int. J. Oncol. |
pmid:18813790
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Van Wagoner DR and Nattel S |
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18817781
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