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Trichostatin A alters the expression of cell cycle controlling genes and microRNAs in donor cells and subsequently improves the yield and quality of cloned bovine embryos in vitro. |
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Theriogenology |
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The histone deacetylase inhibitor trichostatin A induces neurite outgrowth in PC12 cells via the epigenetically regulated expression of the nur77 gene. |
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Interferon regulatory factor 8 functions as a tumor suppressor in renal cell carcinoma and its promoter methylation is associated with patient poor prognosis. |
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PLoS ONE |
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Resveratrol attenuates the release of inflammatory cytokines from human bronchial smooth muscle cells exposed to lipoteichoic acid in chronic obstructive pulmonary disease. |
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MicroRNA-7 protects against 1-methyl-4-phenylpyridinium-induced cell death by targeting RelA. |
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Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). |
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Int J Mol Sci |
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Mediator MED18 subunit plays a negative role in transcription via the CDK/cyclin module. |
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Genes Cells |
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Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels. |
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DNA Repair (Amst.) |
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Inhibition of HDAC3 as a strategy for developing novel diabetes therapeutics. |
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Epigenomics |
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Epigenetic modulation of neuronal apoptosis and cognitive functions in sepsis-associated encephalopathy. |
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Neurol. Sci. |
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Histone deacetylase inhibitors trichostatin A and vorinostat inhibit TGFβ2-induced lens epithelial-to-mesenchymal cell transition. |
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Invest. Ophthalmol. Vis. Sci. |
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Dev. Genes Evol. |
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The histone deacetylase inhibitor trichostatin a promotes totipotency in the male gametophyte. |
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Plant Cell |
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Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial-mesenchymal transition in retinal pigment epithelium cells. |
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J. Cell. Mol. Med. |
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Trichostatin A specifically stimulates gonadotropin FSHβ gene expression in gonadotroph LβT2 cells. |
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5-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines. |
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Trichostatin A increases the levels of plasma gelsolin and amyloid beta-protein in a transgenic mouse model of Alzheimer's disease. |
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Life Sci. |
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Secreted phospholipases Aâ‚‚are differentially expressed and epigenetically silenced in human breast cancer cells. |
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Biochem. Biophys. Res. Commun. |
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Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity. |
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PLoS ONE |
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Histone deacetylase inhibitors trichostatin A and suberoylanilide hydroxamic acid attenuate ventilator-induced lung injury. |
2014 |
Pharmazie |
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Histone deacetylase inhibitors in glioblastoma: pre-clinical and clinical experience. |
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Med. Oncol. |
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Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network. |
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J. Cell. Sci. |
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Novel insights into appropriate encapsulation methods for bioactive compounds into polymers: a study with peptides and HDAC inhibitors. |
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Macromol Biosci |
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Superior Versus Inferior Vestibular Neuritis: Are There Intrinsic Differences in Infection, Reactivation, or Production of Infectious Particles Between the Vestibular Ganglia? |
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A new trichostatin analog from Streptomyces sp. CPCC 203909. |
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J Asian Nat Prod Res |
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Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer. |
2015 |
Sci Rep |
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Epigenetics and miRNA as predictive markers and targets for lung cancer chemotherapy. |
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Cancer Biol. Ther. |
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Trichostatin A rescues the disrupted imprinting induced by somatic cell nuclear transfer in pigs. |
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PLoS ONE |
pmid:25962071
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Regulation of Oxidative Stress in Pulmonary Artery Endothelium. Modulation of Extracellular Superoxide Dismutase and NOX4 Expression Using Histone Deacetylase Class I Inhibitors. |
2015 |
Am. J. Respir. Cell Mol. Biol. |
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Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity. |
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Oncogene |
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Methylation of Integrin α4 and E-Cadherin Genes in Human Prostate Cancer. |
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Pathol. Oncol. Res. |
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Protection against reperfusion lung injury via aborgating multiple signaling cascades by trichostatin A. |
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Int. Immunopharmacol. |
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Trichostatin A, a histone deacetylase inhibitor, reverses epithelial-mesenchymal transition in colorectal cancer SW480 and prostate cancer PC3 cells. |
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Biochem. Biophys. Res. Commun. |
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Effect of LIV1 on the sensitivity of ovarian cancer cells to trichostatin A. |
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Oncol. Rep. |
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Histone deacetylase inhibitor, trichostatin A, improves learning and memory in high-fat diet-induced cognitive deficits in mice. |
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Sodium valproate, a histone deacetylase inhibitor, modulates the vascular endothelial growth inhibitor-mediated cell death in human osteosarcoma and vascular endothelial cells. |
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Int. J. Oncol. |
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Neuroprotective capabilities of TSA against cerebral ischemia/reperfusion injury via PI3K/Akt signaling pathway in rats. |
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Int. J. Neurosci. |
pmid:24730998
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TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells. |
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Cancer Biother. Radiopharm. |
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Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). |
2015 |
Mol. Cell Proteomics |
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Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities. |
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Neurosci. Res. |
pmid:26260244
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Ectopic hbox12 Expression Evoked by Histone Deacetylase Inhibition Disrupts Axial Specification of the Sea Urchin Embryo. |
2015 |
PLoS ONE |
pmid:26618749
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Zhang Y et al. |
The Induction Effect of Am80 and TSA on ESC Differentiation via Regulation of Stra8 in Chicken. |
2015 |
PLoS ONE |
pmid:26606052
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Histone deacetylase enzymes as drug targets for the control of the sheep blowfly, Lucilia cuprina. |
2015 |
Int J Parasitol Drugs Drug Resist |
pmid:27120067
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Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC). |
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Eur. J. Immunol. |
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HDAC inhibitor prevents LPS mediated inhibition of CYP19A1 expression and 17β-estradiol production in granulosa cells. |
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Mol. Cell. Endocrinol. |
pmid:26213324
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Global histone modifications in Fumonisin B1 exposure in rat kidney epithelial cells. |
2015 |
Toxicol In Vitro |
pmid:26208285
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Promotion of Metastasis-associated Gene Expression in Survived PANC-1 Cells Following Trichostatin A Treatment. |
2015 |
Anticancer Agents Med Chem |
pmid:25991546
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