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Chromatin structure and expression of the AMPA receptor subunit Glur2 in human glioma cells: major regulatory role of REST and Sp1. |
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Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo. |
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Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB. |
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PLoS ONE |
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CIITA is silenced by epigenetic mechanisms that prevent the recruitment of transactivating factors in rhabdomyosarcoma cells. |
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Plant Signal Behav |
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J. Reprod. Dev. |
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Am. J. Respir. Cell Mol. Biol. |
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The primordial follicle reserve is not renewed after chemical or γ-irradiation mediated depletion. |
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Reproduction |
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Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3. |
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Diabetes |
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Histone deacetylase inhibitors induced differentiation and accelerated mineralization of pulp-derived cells. |
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Cell Reprogram |
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Biomed. Pharmacother. |
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Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage. |
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Inhibition of class II histone deacetylase blocks proliferation and promotes neuronal differentiation of the embryonic rat neural progenitor cells. |
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Acta Neurobiol Exp (Wars) |
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Histone deacetylase inhibitors upregulate MMP11 gene expression through Sp1/Smad complexes in human colon adenocarcinoma cells. |
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Biochim. Biophys. Acta |
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Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells. |
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Biochim. Biophys. Acta |
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CYP2S1 is negatively regulated by corticosteroids in human cell lines. |
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WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors. |
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PLoS ONE |
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Br. J. Cancer |
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HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons. |
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Hippocampus |
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Prostaglandin E2 induces growth inhibition, apoptosis and differentiation in T and B cell-derived acute lymphoblastic leukemia cell lines (CCRF-CEM and Nalm-6). |
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Prostaglandins Leukot. Essent. Fatty Acids |
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Histone deacetylases regulate gonadotropin-releasing hormone I gene expression via modulating Otx2-driven transcriptional activity. |
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PLoS ONE |
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Targeting the MAGE A3 antigen in pancreatic cancer. |
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Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression. |
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Arch. Immunol. Ther. Exp. (Warsz.) |
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PLoS ONE |
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Mediators Inflamm. |
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Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells. |
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Gastroenterology |
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Gene |
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ARD1 binding to RIP1 mediates doxorubicin-induced NF-κB activation. |
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Biochem. Biophys. Res. Commun. |
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Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation. |
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Hyperoxia arrests alveolar development through suppression of histone deacetylases in neonatal rats. |
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Histone hyperacetylation during meiosis interferes with large-scale chromatin remodeling, axial chromatid condensation and sister chromatid separation in the mammalian oocyte. |
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Use of mouse hematopoietic stem and progenitor cells to treat acute kidney injury. |
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Am. J. Physiol. Renal Physiol. |
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[Cerebral protection of Trichostatin A preconditioning in rats with middle cerebral artery occlusion and the relationship between Trichostatin A and IL-1β]. |
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Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:22561570
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Histone deacetylase inhibition modulates E-cadherin expression and suppresses migration and invasion of anaplastic thyroid cancer cells. |
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J. Clin. Endocrinol. Metab. |
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Trichostatin A ameliorates myocardial ischemia/reperfusion injury through inhibition of endoplasmic reticulum stress-induced apoptosis. |
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Arch. Med. Res. |
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