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The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
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Cell. Mol. Life Sci. |
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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
2001 |
J. Biol. Chem. |
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A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
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Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. |
2001 |
Biochem. J. |
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Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. |
2001 |
Cancer Res. |
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Steinbac OC et al. |
Histone deacetylase activity is required for the induction of the MyoD muscle cell lineage in Xenopus. |
2000 Sep-Oct |
Biol. Chem. |
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Dressel U et al. |
Promoter specific sensitivity to inhibition of histone deacetylases: implications for hormonal gene control, cellular differentiation and cancer. |
2000 Mar-Apr |
Anticancer Res. |
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Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species. |
2000 |
J. Biol. Chem. |
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Mariadason JM et al. |
Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. |
2000 |
Cancer Res. |
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Gray SG et al. |
Modulating IGFBP-3 expression by trichostatin A: potential therapeutic role in the treatment of hepatocellular carcinoma. |
2000 |
Int. J. Mol. Med. |
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Chen WY and Townes TM |
Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
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Xiao H et al. |
p300 collaborates with Sp1 and Sp3 in p21(waf1/cip1) promoter activation induced by histone deacetylase inhibitor. |
2000 |
J. Biol. Chem. |
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Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. |
2000 |
J. Biol. Chem. |
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Eickhoff B et al. |
Trichostatin A modulates expression of p21waf1/cip1, Bcl-xL, ID1, ID2, ID3, CRAB2, GATA-2, hsp86 and TFIID/TAFII31 mRNA in human lung adenocarcinoma cells. |
2000 |
Biol. Chem. |
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Lee SK et al. |
Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor. |
2000 |
J. Biol. Chem. |
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Zhang HS et al. |
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. |
2000 |
Cell |
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Fu M et al. |
p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. |
2000 |
J. Biol. Chem. |
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Gays F et al. |
The mouse tumor cell lines EL4 and RMA display mosaic expression of NK-related and certain other surface molecules and appear to have a common origin. |
2000 |
J. Immunol. |
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McInerney JM et al. |
Long-term silencing of retroviral vectors is resistant to reversal by trichostatin A and 5-azacytidine. |
2000 |
Gene Ther. |
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McBlane F and Boyes J |
Stimulation of V(D)J recombination by histone acetylation. |
2000 |
Curr. Biol. |
pmid:10801420
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Hobbs CA and Gilmour SK |
High levels of intracellular polyamines promote histone acetyltransferase activity resulting in chromatin hyperacetylation. |
2000 |
J. Cell. Biochem. |
pmid:10760944
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Diamond SE and Gutierrez-Hartmann A |
The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter. |
2000 |
J. Biol. Chem. |
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Andoh A et al. |
Modulation of complement component (C3 and factor B) biosynthesis by a histone deacetylase inhibitor in human intestinal epithelial cells. |
2000 |
Int. J. Mol. Med. |
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Effect of trichostatin A on cell growth and expression of cell cycle- and apoptosis-related molecules in human gastric and oral carcinoma cell lines. |
2000 |
Int. J. Cancer |
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Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription. |
2000 |
Mol. Cell. Biol. |
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Magner WJ et al. |
Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors. |
2000 |
J. Immunol. |
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Damjanovski S et al. |
Multiple stage-dependent roles for histone deacetylases during amphibian embryogenesis: implications for the involvement of extracellular matrix remodeling. |
2000 |
Int. J. Dev. Biol. |
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Liang L et al. |
Dynamic readjustment of parental methylation patterns of the 5'-flank of the mouse H19 gene during in vitro organogenesis. |
2000 |
Int. J. Dev. Biol. |
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Transcriptionally active drugs improve adenovirus vector performance in vitro and in vivo. |
2000 |
Gene Ther. |
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Maecker HL et al. |
p53 promotes selection for Fas-mediated apoptotic resistance. |
2000 |
Cancer Res. |
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Asoh S et al. |
The super anti-apoptotic factor Bcl-xFNK constructed by disturbing intramolecular polar interactions in rat Bcl-xL. |
2000 |
J. Biol. Chem. |
pmid:10970895
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Cong YS and Bacchetti S |
Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells. |
2000 |
J. Biol. Chem. |
pmid:10986277
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Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing. |
2000 |
J. Biol. Chem. |
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Badia E et al. |
Long-term hydroxytamoxifen treatment of an MCF-7-derived breast cancer cell line irreversibly inhibits the expression of estrogenic genes through chromatin remodeling. |
2000 |
Cancer Res. |
pmid:10945620
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Wharton W et al. |
Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes. |
2000 |
J. Biol. Chem. |
pmid:10945992
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Zhou Q et al. |
Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1. |
2000 |
J. Biol. Chem. |
pmid:10938272
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Xu RH et al. |
Histone acetylation is a checkpoint in FGF-stimulated mesoderm induction. |
2000 |
Dev. Dyn. |
pmid:10906781
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Gray SG et al. |
IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a. |
2000 |
Cytokine |
pmid:10880258
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Su GH et al. |
A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. |
2000 |
Cancer Res. |
pmid:10866300
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Lin F et al. |
Unique anti-activator protein-1 activity of retinoic acid receptor beta. |
2000 |
Cancer Res. |
pmid:10866321
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Hemavathy K et al. |
Human Slug is a repressor that localizes to sites of active transcription. |
2000 |
Mol. Cell. Biol. |
pmid:10866665
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Jin S et al. |
Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10841572
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Sirchia SM et al. |
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells. |
2000 |
Oncogene |
pmid:10734315
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DiRenzo J et al. |
BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. |
2000 |
Mol. Cell. Biol. |
pmid:11003650
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Hu JF et al. |
Allele-specific histone acetylation accompanies genomic imprinting of the insulin-like growth factor II receptor gene. |
2000 |
Endocrinology |
pmid:11108251
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Eickhoff B et al. |
Trichostatin A-mediated regulation of gene expression and protein kinase activities: reprogramming tumor cells for ribotoxic stress-induced apoptosis. |
2000 |
Biol. Chem. |
pmid:11154071
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Yang X et al. |
Transcriptional activation of estrogen receptor alpha in human breast cancer cells by histone deacetylase inhibition. |
2000 |
Cancer Res. |
pmid:11156387
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Nakayama T et al. |
Epigenetic regulation of androgen receptor gene expression in human prostate cancers. |
2000 |
Lab. Invest. |
pmid:11140692
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Pender SL et al. |
Butyrate upregulates stromelysin-1 production by intestinal mesenchymal cells. |
2000 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:11052988
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Tobias CA et al. |
Improved recombinant retroviral titers utilizing trichostatin A. |
2000 |
BioTechniques |
pmid:11056820
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