Takahashi K et al. |
Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer. |
2006 |
Int. J. Oncol. |
pmid:16391785
|
Bai T et al. |
A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells. |
2006 |
Int. J. Oncol. |
pmid:16391806
|
Pazmany T and Tomasi TB |
The major histocompatibility complex class II transactivator is differentially regulated by interferon-gamma and transforming growth factor-beta in microglial cells. |
2006 |
J. Neuroimmunol. |
pmid:16360884
|
Lee KY et al. |
NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. |
2006 |
J. Immunol. |
pmid:16365456
|
Ohnishi K |
[Therapeutic strategies for patients with relapsed acute promyelocytic leukemia]. |
2006 |
Rinsho Ketsueki |
pmid:16986710
|
Hansen KR et al. |
Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1. |
2006 |
Nucleic Acids Res. |
pmid:16407326
|
Dowdy SC et al. |
Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells. |
2006 |
Mol. Cancer Ther. |
pmid:17121923
|
Fischer S et al. |
Histone acetylation dependent allelic expression imbalance of BAPX1 in patients with the oculo-auriculo-vertebral spectrum. |
2006 |
Hum. Mol. Genet. |
pmid:16407370
|
Saunders LR and Verdin E |
Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors. |
2006 |
Mol. Cancer Ther. |
pmid:17121924
|
Bieler A et al. |
Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520. |
2006 |
Hum. Gene Ther. |
pmid:16409125
|
Lo PK et al. |
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. |
2006 |
Cancer Biol. Ther. |
pmid:16410723
|
Williams SA et al. |
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. |
2006 |
EMBO J. |
pmid:16319923
|
ChuÄkin IA et al. |
[Anti-proliferative effect of histone deacetylase inhibitors on murine embryonic stem cells]. |
2006 |
Tsitologiia |
pmid:17147260
|
Zou B et al. |
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. |
2006 |
Gastroenterology |
pmid:17087954
|
Anderson I |
Deacetylase inhibitors aid recovery in muscular dystrophy. |
2006 |
Lancet Neurol |
pmid:17089447
|
Kiefer J et al. |
Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. |
2006 |
Br. J. Nutr. |
pmid:17092367
|
Stefanovsky V and Moss T |
Regulation of rRNA synthesis in human and mouse cells is not determined by changes in active gene count. |
2006 |
Cell Cycle |
pmid:16582637
|
Wang Q et al. |
Histone deacetylation is required for orderly meiosis. |
2006 |
Cell Cycle |
pmid:16582639
|
Magnaghi-Jaulin L and Jaulin C |
Histone deacetylase activity is necessary for chromosome condensation during meiotic maturation in Xenopus laevis. |
2006 |
Chromosome Res. |
pmid:16628502
|
Pavan Kumar P et al. |
Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. |
2006 |
Mol. Cell |
pmid:16630892
|
Vinken M et al. |
Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes. |
2006 |
Toxicol. Sci. |
pmid:16531468
|
Gastaldi T et al. |
Plakoglobin is differentially expressed in alveolar and embryonal rhabdomyosarcoma and is regulated by DNA methylation and histone acetylation. |
2006 |
Carcinogenesis |
pmid:16537559
|
Tada Y et al. |
Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer. |
2006 |
J. Natl. Cancer Inst. |
pmid:16537832
|
Bishop CL et al. |
Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA. |
2006 |
Mol. Cell. Biol. |
pmid:16537904
|
Gagnon JF et al. |
Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. |
2006 |
Clin. Cancer Res. |
pmid:16551870
|
Rebbaa A et al. |
The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis. |
2006 |
Cell Death Differ. |
pmid:16557274
|
Suuronen T et al. |
Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. |
2006 |
Neurochem. Int. |
pmid:16797784
|
Wallace DM et al. |
Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:16799012
|
Zampetaki A et al. |
TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16814255
|
Jüngel A et al. |
Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis. |
2006 |
Ann. Rheum. Dis. |
pmid:16284094
|
Nygård M et al. |
Thyroid hormone-mediated negative transcriptional regulation of Necdin expression. |
2006 |
J. Mol. Endocrinol. |
pmid:16720720
|
Armstrong K et al. |
NF-kappaB activation upregulates fibroblast growth factor 8 expression in prostate cancer cells. |
2006 |
Prostate |
pmid:16683270
|
Wischnewski F et al. |
Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. |
2006 |
Mol. Cancer Res. |
pmid:16687489
|
Yamada N et al. |
MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. |
2006 |
Int. J. Cancer |
pmid:16721789
|
Kim Y et al. |
Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. |
2006 |
J. Steroid Biochem. Mol. Biol. |
pmid:16723222
|
Santander VS et al. |
Tubulin must be acetylated in order to form a complex with membrane Na(+),K (+)-ATPase and to inhibit its enzyme activity. |
2006 |
Mol. Cell. Biochem. |
pmid:16733802
|
Kong Y et al. |
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. |
2006 |
Circulation |
pmid:16735673
|
Dannenberg LO et al. |
Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. |
2006 |
Alcohol. Clin. Exp. Res. |
pmid:16737450
|
Cabrero JR et al. |
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. |
2006 |
Mol. Biol. Cell |
pmid:16738306
|
Vulcano F et al. |
HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers. |
2006 |
Exp. Cell Res. |
pmid:16739251
|
Balasubramaniyan V et al. |
Effects of histone deacetylation inhibition on neuronal differentiation of embryonic mouse neural stem cells. |
2006 |
Neuroscience |
pmid:17084985
|
Zhang Y et al. |
Phosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of transcription of the luteinizing hormone receptor gene. |
2006 |
Mol. Cell. Biol. |
pmid:16943418
|
Stewart MD et al. |
Dynamic regulation of histone modifications in Xenopus oocytes through histone exchange. |
2006 |
Mol. Cell. Biol. |
pmid:16943430
|
Mühlisch J et al. |
Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood. |
2006 |
Oncogene |
pmid:16186793
|
Hirsch CL et al. |
Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells. |
2006 |
Int. J. Cancer |
pmid:16094635
|
Scott SA et al. |
5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation. |
2006 |
Leuk. Res. |
pmid:16043219
|
Hofmann A et al. |
Epigenetic regulation of lentiviral transgene vectors in a large animal model. |
2006 |
Mol. Ther. |
pmid:16140581
|
Clem BF and Clark BJ |
Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene. |
2006 |
Mol. Endocrinol. |
pmid:16109738
|
Kim HR et al. |
Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway? |
2006 |
Exp. Mol. Med. |
pmid:17202837
|
Mai A et al. |
Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. |
2006 |
J. Med. Chem. |
pmid:17004718
|
Yao J et al. |
NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. |
2006 |
Pharmacol. Res. |
pmid:17005413
|
Inoue K et al. |
Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17008592
|
Baqir S and Smith LC |
Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. |
2006 |
Cloning Stem Cells |
pmid:17009896
|
Bai J et al. |
Histone deacetylase inhibitor trichostatin A and proteasome inhibitor PS-341 synergistically induce apoptosis in pancreatic cancer cells. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16904634
|
Charrier C et al. |
Synthesis of rigid trichostatin A analogs as HDAC inhibitors. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16904890
|
Okamoto H et al. |
Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). |
2006 |
J. Atheroscler. Thromb. |
pmid:16908950
|
Claus R et al. |
Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression. |
2006 |
J. Leukoc. Biol. |
pmid:17000900
|
Kogai T et al. |
Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. |
2006 |
Endocr. Relat. Cancer |
pmid:16954431
|
Tyson-Capper AJ et al. |
Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy. |
2006 |
Mol. Hum. Reprod. |
pmid:16959971
|
Chen J et al. |
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells. |
2006 |
Pharmazie |
pmid:16964716
|
Kim MY et al. |
A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16924111
|
Mühlethaler-Mottet A et al. |
Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. |
2006 |
BMC Cancer |
pmid:16930472
|
Suzuki T et al. |
Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. |
2006 |
J. Med. Chem. |
pmid:16884291
|
Seo H et al. |
An ex vivo method for rapid generation of monoclonal antibodies (ADLib system). |
2006 |
Nat Protoc |
pmid:17406441
|
Pedram M et al. |
Telomere position effect and silencing of transgenes near telomeres in the mouse. |
2006 |
Mol. Cell. Biol. |
pmid:16479005
|
Rybouchkin A et al. |
Role of histone acetylation in reprogramming of somatic nuclei following nuclear transfer. |
2006 |
Biol. Reprod. |
pmid:16481594
|
Banchio C et al. |
Role of histone deacetylase in the expression of CTP:phosphocholine cytidylyltransferase alpha. |
2006 |
J. Biol. Chem. |
pmid:16484221
|
Weaver IC et al. |
Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16484373
|
Fandy TE and Srivastava RK |
Trichostatin A sensitizes TRAIL-resistant myeloma cells by downregulation of the antiapoptotic Bcl-2 proteins. |
2006 |
Cancer Chemother. Pharmacol. |
pmid:16435155
|
Deng G et al. |
Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. |
2006 |
Int. J. Cancer |
pmid:16425274
|
Huang L et al. |
Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression. |
2006 |
Neurosci. Lett. |
pmid:16426753
|
Kim IA et al. |
Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53. |
2006 |
Clin. Cancer Res. |
pmid:16467109
|
Osborn NK et al. |
Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. |
2006 |
Clin. Gastroenterol. Hepatol. |
pmid:16469682
|
Baraz L et al. |
Tumor suppressor p53 regulates heparanase gene expression. |
2006 |
Oncogene |
pmid:16474844
|
Gialitakis M et al. |
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. |
2006 |
Nucleic Acids Res. |
pmid:16452299
|
Kwon HS et al. |
Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. |
2006 Mar-Apr |
Biochim. Biophys. Acta |
pmid:16757381
|
Sakuma M et al. |
Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer. |
2007 |
Cancer Sci. |
pmid:17270028
|
Kim SH et al. |
Regulation of the HIF-1alpha stability by histone deacetylases. |
2007 |
Oncol. Rep. |
pmid:17273746
|
Ou JN et al. |
Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. |
2007 |
Biochem. Pharmacol. |
pmid:17276411
|
Hatjiharissi E et al. |
Proteomic analysis of waldenstrom macroglobulinemia. |
2007 |
Cancer Res. |
pmid:17440091
|
Yoshikawa M et al. |
Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-beta1 in human renal epithelial cells. |
2007 |
J. Am. Soc. Nephrol. |
pmid:17135397
|
Reddy RM et al. |
Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade. |
2007 |
Apoptosis |
pmid:17136498
|
Tuncel M et al. |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. |
2007 |
Cancer Biother. Radiopharm. |
pmid:17679169
|
Sun DF et al. |
[The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines]. |
2007 |
Zhonghua Yi Xue Yi Chuan Xue Za Zhi |
pmid:17680526
|
Wu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, attenuates invasiveness and reactivates E-cadherin expression in immortalized endometriotic cells. |
2007 |
Reprod Sci |
pmid:17644810
|
Wang CT and Meng M |
[Experimental study on the effect of trichostatin A on differentiation of human lung carcinoma cell]. |
2007 |
Zhonghua Yi Xue Za Zhi |
pmid:17650409
|
Janowski BA et al. |
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. |
2007 |
Nat. Chem. Biol. |
pmid:17259978
|
Woo HJ et al. |
Induction of apoptosis and inhibition of telomerase activity by trichostatin A, a histone deacetylase inhibitor, in human leukemic U937 cells. |
2007 |
Exp. Mol. Pathol. |
pmid:16574101
|
Januchowski R et al. |
Trichostatin A down-regulate DNA methyltransferase 1 in Jurkat T cells. |
2007 |
Cancer Lett. |
pmid:16624484
|
Frye M et al. |
Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. |
2007 |
PLoS ONE |
pmid:17712411
|
Adcock IM et al. |
Epigenetic regulation of airway inflammation. |
2007 |
Curr. Opin. Immunol. |
pmid:17720468
|
Zhang Y et al. |
Attenuated DNA damage repair by trichostatin A through BRCA1 suppression. |
2007 |
Radiat. Res. |
pmid:17722998
|
Zhong S et al. |
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer. |
2007 |
Oncogene |
pmid:17043644
|
Katz RA et al. |
High-frequency epigenetic repression and silencing of retroviruses can be antagonized by histone deacetylase inhibitors and transcriptional activators, but uniform reactivation in cell clones is restricted by additional mechanisms. |
2007 |
J. Virol. |
pmid:17202206
|
Pourebrahim R et al. |
ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations. |
2007 |
FEBS Lett. |
pmid:17936758
|
Sichtig N et al. |
Papillomavirus binding factor binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex. |
2007 |
Arch. Biochem. Biophys. |
pmid:17897615
|
Charrier C et al. |
Antiproliferative activities of a library of hybrids between indanones and HDAC inhibitor SAHA and MS-275 analogues. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17897824
|
Barr H et al. |
Mbd2 contributes to DNA methylation-directed repression of the Xist gene. |
2007 |
Mol. Cell. Biol. |
pmid:17353271
|
Li B et al. |
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:17360565
|
Vandergeeten C et al. |
HIV-1 protease inhibitors do not interfere with provirus transcription and host cell apoptosis induced by combined treatment TNF-alpha + TSA. |
2007 |
Biochem. Pharmacol. |
pmid:17386923
|