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Gene |
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Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma. |
2007 |
Hepatology |
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Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines. |
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Biomed. Pharmacother. |
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Oncogene |
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Genes Cells |
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Cell Prolif. |
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Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. |
2007 |
Immunology |
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2007 |
Stem Cells |
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Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells. |
2007 |
Stem Cells |
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CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A. |
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Neoplasia |
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Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. |
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Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. |
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Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer. |
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The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy. |
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Int. J. Cancer |
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Trichostatin A blocks TGF-beta-induced collagen gene expression in skin fibroblasts: involvement of Sp1. |
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Trichostatin A down-regulates ZAP-70, LAT and SLP-76 content in Jurkat T cells. |
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Oncogene |
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Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments. |
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Oncogene |
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A metabolic screening study of trichostatin A (TSA) and TSA-like histone deacetylase inhibitors in rat and human primary hepatocyte cultures. |
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J. Pharmacol. Exp. Ther. |
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The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma. |
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Cancer Genet. Cytogenet. |
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Dynamic reprogramming of histone acetylation and methylation in the first cell cycle of cloned mouse embryos. |
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Biol. Reprod. |
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High-frequency epigenetic repression and silencing of retroviruses can be antagonized by histone deacetylase inhibitors and transcriptional activators, but uniform reactivation in cell clones is restricted by additional mechanisms. |
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J. Virol. |
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Combined effects of retinoic acid and histone deacetylase inhibitors on human neuroblastoma SH-SY5Y cells. |
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[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. |
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Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent. |
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Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene. |
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Gastroenterology |
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Deacetylase inhibition promotes the generation and function of regulatory T cells. |
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[The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. |
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Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator. |
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J. Biol. Chem. |
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Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in susceptibility to histone deacetylase inhibitors. |
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Regulation of the CLDN3 gene in ovarian cancer cells. |
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Cancer Biol. Ther. |
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Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. |
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Neuron |
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Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours. |
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Br. J. Cancer |
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Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. |
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Mol. Cell |
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Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation. |
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Cancer Res. |
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HIV-1 protease inhibitors do not interfere with provirus transcription and host cell apoptosis induced by combined treatment TNF-alpha + TSA. |
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Biochem. Pharmacol. |
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Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis. |
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Leuk. Res. |
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Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation. |
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Up-regulation of ras-GAP genes is reversed by a MEK inhibitor and doxorubicin in v-Ki-ras-transformed NIH/3T3 fibroblasts. |
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Biochem. Biophys. Res. Commun. |
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ERas oncogene expression and epigenetic regulation by histone acetylation in human cancer cells. |
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The histone deacetylase inhibitor butyrate inhibits melanoma cell invasion of Matrigel. |
2007 Nov-Dec |
Anticancer Res. |
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Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2. |
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Biochim. Biophys. Acta |
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[The role of DNA methylation and histone modifications in structural maintainance of heterochromatin domains (chromocenters)]. |
2008 |
Tsitologiia |
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Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40. |
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Genes Cells |
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Sensitive, specific, and quantitative FTICR mass spectrometry of combinatorial post-translational modifications in intact histone H4. |
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Anal. Chem. |
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Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent. |
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Angiogenesis |
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A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts. |
2008 |
Cell Cycle |
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Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. |
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Int. J. Oncol. |
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