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A histone deacetylation-dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells. |
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Prostate |
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NF-kappaB inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells. |
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Carcinogenesis |
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Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS. |
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Am. J. Physiol. Endocrinol. Metab. |
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Inhibition of proliferation of endometrial stromal cells by trichostatin A, RU486, CDB-2914, N-acetylcysteine, and ICI 182780. |
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Histone deacetylase inhibitor trichostatin A inhibits the growth of bladder cancer cells through induction of p21WAF1 and G1 cell cycle arrest. |
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In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL. |
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Cancer Gene Ther. |
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Targeted histone H4 acetylation via phosphoinositide 3-kinase- and p70s6-kinase-dependent pathways inhibits iNOS induction in mesangial cells. |
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Am. J. Physiol. Renal Physiol. |
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Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells. |
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Mol. Cancer Ther. |
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Effect of Trichostatin A on CD4 surface density in peripheral blood T cells. |
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Folia Histochem. Cytobiol. |
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Trichostatin A regulates hGCN5 expression and cell cycle on Daudi cells in vitro. |
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Histone phosphorylation and pericentromeric histone modifications in oocyte meiosis. |
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Cell Cycle |
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Androgen receptor regulates nuclear trafficking and nuclear domain residency of corepressor HDAC7 in a ligand-dependent fashion. |
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SET-mediated promoter hypoacetylation is a prerequisite for coactivation of the estrogen-responsive pS2 gene by PRMT1. |
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Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. |
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Oncol. Rep. |
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Histone deacetylase 3 represses HTLV-1 tax transcription. |
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Oncol. Rep. |
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The histone deacetylase inhibitor trichostatin a has genotoxic effects in human lymphoblasts in vitro. |
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Toxicol. Sci. |
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Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation. |
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Oncogene |
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Trichostatin A enhances the response of chemotherapeutic agents in inhibiting pancreatic cancer cell proliferation. |
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Virchows Arch. |
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The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines. |
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Mol. Cancer |
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Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells. |
2006 |
Mol. Cancer |
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Lipid rafts remodeling in estrogen receptor-negative breast cancer is reversed by histone deacetylase inhibitor. |
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Mol. Cancer Ther. |
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Mol. Cancer Ther. |
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Mol. Cell. Biol. |
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Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents. |
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Exp. Hematol. |
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