Kim HR et al. |
Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway? |
2006 |
Exp. Mol. Med. |
pmid:17202837
|
McCool KW et al. |
The role of histone acetylation in regulating early gene expression patterns during early embryonic stem cell differentiation. |
2007 |
J. Biol. Chem. |
pmid:17204470
|
Bártová E et al. |
Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites. |
2007 |
Histochem. Cell Biol. |
pmid:17205308
|
Kuang PP et al. |
Activation of elastin transcription by transforming growth factor-beta in human lung fibroblasts. |
2007 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:17209135
|
Cras A et al. |
Epigenetic patterns of the retinoic acid receptor beta2 promoter in retinoic acid-resistant thyroid cancer cells. |
2007 |
Oncogene |
pmid:17213810
|
Karagiannis TC et al. |
Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments. |
2007 |
Oncogene |
pmid:17213813
|
Elaut G et al. |
A metabolic screening study of trichostatin A (TSA) and TSA-like histone deacetylase inhibitors in rat and human primary hepatocyte cultures. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17218485
|
Kozłowska A and Jagodziński PP |
Effect of Trichostatin A on CD4 surface density in peripheral blood T cells. |
2006 |
Folia Histochem. Cytobiol. |
pmid:17219719
|
He J et al. |
Effects of trichostatin A on HDAC8 expression, proliferation and cell cycle of Molt-4 cells. |
2006 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:17219959
|
Liu H et al. |
Trichostatin A regulates hGCN5 expression and cell cycle on Daudi cells in vitro. |
2006 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:17219960
|
Sun C et al. |
Anticancer activities of trichostatin A on maligant lymphoid cells. |
2006 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:17219961
|
Ting CH et al. |
Stat5 constitutive activation rescues defects in spinal muscular atrophy. |
2007 |
Hum. Mol. Genet. |
pmid:17220171
|
Feng W et al. |
Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer. |
2007 |
Int. J. Cancer |
pmid:17230502
|
Karam JA et al. |
The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy. |
2007 |
Int. J. Cancer |
pmid:17230511
|
Ghosh AK et al. |
Trichostatin A blocks TGF-beta-induced collagen gene expression in skin fibroblasts: involvement of Sp1. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17234156
|
Li Y et al. |
Regulation of neuronal nitric oxide synthase exon 1f gene expression by nuclear factor-kappaB acetylation in human neuroblastoma cells. |
2007 |
J. Neurochem. |
pmid:17250678
|
Suzuki T et al. |
Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17257837
|
Scott SA et al. |
Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression. |
2007 |
Exp. Hematol. |
pmid:17258075
|
Ishihara K et al. |
Differentiation of eosinophilic leukemia EoL-1 cells into eosinophils induced by histone deacetylase inhibitors. |
2007 |
Life Sci. |
pmid:17258775
|
Janowski BA et al. |
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. |
2007 |
Nat. Chem. Biol. |
pmid:17259978
|
Oyama T et al. |
Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo. |
2007 |
J. Cell Biol. |
pmid:17261849
|
Nagashima T et al. |
Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis. |
2007 |
Mol. Hum. Reprod. |
pmid:17267518
|
Sakuma M et al. |
Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer. |
2007 |
Cancer Sci. |
pmid:17270028
|
Han S et al. |
HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region. |
2007 |
Immunol. Lett. |
pmid:17270283
|
Kim SH et al. |
Regulation of the HIF-1alpha stability by histone deacetylases. |
2007 |
Oncol. Rep. |
pmid:17273746
|
Sugita K et al. |
Morphological reversion of sis-transformed NIH3T3 cells by trichostatin A. |
1992 |
Cancer Res. |
pmid:1727377
|
Ou JN et al. |
Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. |
2007 |
Biochem. Pharmacol. |
pmid:17276411
|
Wu Y and Guo SW |
Suppression of IL-1beta-induced COX-2 expression by trichostatin A (TSA) in human endometrial stromal cells. |
2007 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:17296257
|
Appanah R et al. |
An unmethylated 3' promoter-proximal region is required for efficient transcription initiation. |
2007 |
PLoS Genet. |
pmid:17305432
|
Bui HT et al. |
Regulation of chromatin and chromosome morphology by histone H3 modifications in pig oocytes. |
2007 |
Reproduction |
pmid:17307905
|
Yang QC et al. |
Inhibition of hypoxia-induced angiogenesis by trichostatin A via suppression of HIF-1a activity in human osteosarcoma. |
2006 |
J. Exp. Clin. Cancer Res. |
pmid:17310851
|
Mayo C et al. |
In vitro differentiation of HT-29 M6 mucus-secreting colon cancer cells involves a trychostatin A and p27(KIP1)-inducible transcriptional program of gene expression. |
2007 |
J. Cell. Physiol. |
pmid:17311291
|
Sugita K et al. |
A novel compound, depudecin, induces production of transformation to the flat phenotype of NIH3T3 cells transformed by ras-oncogene. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1731795
|
Avila AM et al. |
Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy. |
2007 |
J. Clin. Invest. |
pmid:17318264
|
Di Renzo F et al. |
Boric acid inhibits embryonic histone deacetylases: a suggested mechanism to explain boric acid-related teratogenicity. |
2007 |
Toxicol. Appl. Pharmacol. |
pmid:17320131
|
Xin C et al. |
FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism. |
2007 |
Br. J. Pharmacol. |
pmid:17325654
|
Putignano E et al. |
Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity. |
2007 |
Neuron |
pmid:17329213
|
Vibhakar R et al. |
Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma. |
2007 |
Neuro-oncology |
pmid:17329407
|
Pan L et al. |
Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression. |
2007 |
Cancer |
pmid:17330857
|
Stiehl DP et al. |
Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation. |
2007 |
Cancer Res. |
pmid:17332356
|
Jung J and Bonini N |
CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease. |
2007 |
Science |
pmid:17332375
|
Jaffe RC et al. |
Histone deacetylase inhibition and progesterone act synergistically to stimulate baboon glycodelin gene expression. |
2007 |
J. Mol. Endocrinol. |
pmid:17339403
|
Alimirah F et al. |
IFI16 in human prostate cancer. |
2007 |
Mol. Cancer Res. |
pmid:17339605
|
Vikhanskaya F et al. |
Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53. |
2007 |
Nucleic Acids Res. |
pmid:17344317
|
Krennhrubec K et al. |
Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17346959
|
Hattori N et al. |
Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells. |
2007 |
Genes Cells |
pmid:17352742
|
Barr H et al. |
Mbd2 contributes to DNA methylation-directed repression of the Xist gene. |
2007 |
Mol. Cell. Biol. |
pmid:17353271
|
Li B et al. |
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:17360565
|
Hashii M et al. |
Up-regulation of ras-GAP genes is reversed by a MEK inhibitor and doxorubicin in v-Ki-ras-transformed NIH/3T3 fibroblasts. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17367762
|
Hosseinkhani M et al. |
Trichostatin A induces myocardial differentiation of monkey ES cells. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17368572
|
Kim HJ et al. |
Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17371805
|
Hummel M et al. |
Transcriptional reactivation of murine cytomegalovirus ie gene expression by 5-aza-2'-deoxycytidine and trichostatin A in latently infected cells despite lack of methylation of the major immediate-early promoter. |
2007 |
J. Gen. Virol. |
pmid:17374752
|
Wu Y and Guo SW |
Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells. |
2008 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:17376583
|
Vandergeeten C et al. |
HIV-1 protease inhibitors do not interfere with provirus transcription and host cell apoptosis induced by combined treatment TNF-alpha + TSA. |
2007 |
Biochem. Pharmacol. |
pmid:17386923
|
Rohner A et al. |
Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis. |
2007 |
Leuk. Res. |
pmid:17391757
|
Dompierre JP et al. |
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation. |
2007 |
J. Neurosci. |
pmid:17392473
|
Cao D et al. |
COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1. |
2007 |
Am. J. Respir. Cell Mol. Biol. |
pmid:17395887
|
Seo H et al. |
An ex vivo method for rapid generation of monoclonal antibodies (ADLib system). |
2006 |
Nat Protoc |
pmid:17406441
|
Snykers S et al. |
Chromatin remodeling agent trichostatin A: a key-factor in the hepatic differentiation of human mesenchymal stem cells derived of adult bone marrow. |
2007 |
BMC Dev. Biol. |
pmid:17407549
|
Horion J et al. |
Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha. |
2007 |
J. Biol. Chem. |
pmid:17409387
|
Ryningen A et al. |
Clonogenic acute myelogenous leukemia cells are heterogeneous with regard to regulation of differentiation and effect of epigenetic pharmacological targeting. |
2007 |
Leuk. Res. |
pmid:17416413
|
Chen Y et al. |
Homeobox gene HOP has a potential tumor suppressive activity in human lung cancer. |
2007 |
Int. J. Cancer |
pmid:17417779
|
Liu T et al. |
Design and synthesis of a potent histone deacetylase inhibitor. |
2007 |
J. Med. Chem. |
pmid:17419603
|
De los Santos M et al. |
Combined effects of retinoic acid and histone deacetylase inhibitors on human neuroblastoma SH-SY5Y cells. |
2007 |
Mol. Cancer Ther. |
pmid:17431121
|
Hatjiharissi E et al. |
Proteomic analysis of waldenstrom macroglobulinemia. |
2007 |
Cancer Res. |
pmid:17440091
|
Cecconi D et al. |
Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A. |
2007 |
Proteomics |
pmid:17443844
|
Higashi T et al. |
Histone H2A mobility is regulated by its tails and acetylation of core histone tails. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17445770
|
Hwang CK et al. |
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. |
2007 |
Mol. Cell. Biol. |
pmid:17452465
|
|
[Isolation of drug-resistant mutant cells]. |
1991 |
Tanpakushitsu Kakusan Koso |
pmid:1745788
|
Yi T et al. |
Trichostatin A-mediated upregulation of p21(WAF1) contributes to osteoclast apoptosis. |
2007 |
Exp. Mol. Med. |
pmid:17464183
|
Wong CM et al. |
Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma. |
2007 |
Hepatology |
pmid:17464989
|
Vincent A et al. |
Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells. |
2007 |
Oncogene |
pmid:17471237
|
Zhang C et al. |
Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. |
2007 |
J. Pathol. |
pmid:17471463
|
Gensert JM et al. |
CD81, a cell cycle regulator, is a novel target for histone deacetylase inhibition in glioma cells. |
2007 |
Neurobiol. Dis. |
pmid:17481908
|
Hellebrekers DM et al. |
Identification of epigenetically silenced genes in tumor endothelial cells. |
2007 |
Cancer Res. |
pmid:17483324
|
Piotrowska H and Jagodzinski PP |
Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines. |
2007 |
Biomed. Pharmacother. |
pmid:17498915
|
Iliopoulos D et al. |
Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention. |
2007 |
Ann. Rheum. Dis. |
pmid:17502362
|
Choy SW et al. |
C. elegans SIN-3 and its associated HDAC corepressor complex act as mediators of male sensory ray development. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17506990
|
Royo H et al. |
Bsr, a nuclear-retained RNA with monoallelic expression. |
2007 |
Mol. Biol. Cell |
pmid:17507654
|
de Boer J et al. |
Inhibition of histone acetylation as a tool in bone tissue engineering. |
2006 |
Tissue Eng. |
pmid:17518660
|
Turaga RV et al. |
Werner syndrome protein prevents DNA breaks upon chromatin structure alteration. |
2007 |
Aging Cell |
pmid:17521388
|
Wu J et al. |
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing. |
2007 |
BMC Genomics |
pmid:17524140
|
Schwechter BR et al. |
Histone deacetylase inhibition-mediated differentiation of RGC-5 cells and interaction with survival. |
2007 |
Invest. Ophthalmol. Vis. Sci. |
pmid:17525221
|
Fan J et al. |
[Expression of ER alpha in chemically induced MDA-MB-435 cells and its responsiveness to endocrine]. |
2006 |
Zhonghua Zhong Liu Za Zhi |
pmid:17533736
|
Kaneko M et al. |
Mechanism for the differentiation of EoL-1 cells into eosinophils by histone deacetylase inhibitors. |
2007 |
Int. Arch. Allergy Immunol. |
pmid:17541273
|
Vecsey CG et al. |
Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. |
2007 |
J. Neurosci. |
pmid:17553985
|
Pinnoji RC et al. |
Repressor element-1 silencing transcription factor/neuronal restrictive silencer factor (REST/NRSF) can regulate HSV-1 immediate-early transcription via histone modification. |
2007 |
Virol. J. |
pmid:17555596
|
Khan Z et al. |
HDAC inhibition amplifies gap junction communication in neural progenitors: potential for cell-mediated enzyme prodrug therapy. |
2007 |
Exp. Cell Res. |
pmid:17555745
|
Donadelli M et al. |
Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine. |
2007 |
Biochim. Biophys. Acta |
pmid:17555830
|
Smetana K et al. |
Effect of histone deacetylase inhibitors on the cell nucleus and nucleolus of leukemic myeloblasts in vitro - a cytochemical study. |
2007 |
Acta Histochem. |
pmid:17559910
|
Lin T et al. |
Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver. |
2007 |
Surgery |
pmid:17560255
|
Bai L and Merchant JL |
ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17560543
|
Rigamonti D et al. |
Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators. |
2007 |
J. Biol. Chem. |
pmid:17565993
|
Kitamura H et al. |
Down-regulation of HLA class I antigens in prostate cancer tissues and up-regulation by histone deacetylase inhibition. |
2007 |
J. Urol. |
pmid:17574613
|
Haffner I et al. |
Regulation of arginase-1 expression in macrophages by a protein kinase A type I and histone deacetylase dependent pathway. |
2008 |
J. Cell. Biochem. |
pmid:17577214
|
Huang JC et al. |
Changes in histone acetylation during postovulatory aging of mouse oocyte. |
2007 |
Biol. Reprod. |
pmid:17582009
|
Lee S et al. |
Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17588744
|
Castro-Galache MD et al. |
Protein kinase C-alpha antagonizes apoptosis induction by histone deacetylase inhibitors in multidrug resistant leukaemia cells. |
2007 |
Int. J. Biochem. Cell Biol. |
pmid:17588800
|
Ye J et al. |
De novo protein synthesis is required for lytic cycle reactivation of Epstein-Barr virus, but not Kaposi's sarcoma-associated herpesvirus, in response to histone deacetylase inhibitors and protein kinase C agonists. |
2007 |
J. Virol. |
pmid:17596302
|
Tuncel M et al. |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. |
2007 |
Cancer Biother. Radiopharm. |
pmid:17600477
|