Park H et al. |
Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells. |
2008 |
Int. J. Mol. Med. |
pmid:18949380
|
Lin YC et al. |
Effects of trichostatin A on neuronal mu-opioid receptor gene expression. |
2008 |
Brain Res. |
pmid:18950606
|
Haffner I et al. |
Regulation of arginase-1 expression in macrophages by a protein kinase A type I and histone deacetylase dependent pathway. |
2008 |
J. Cell. Biochem. |
pmid:17577214
|
Björkman M et al. |
Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer. |
2008 |
Int. J. Cancer |
pmid:18798265
|
Oger F et al. |
The class I histone deacetylases of the platyhelminth parasite Schistosoma mansoni. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18977200
|
Albertus DL et al. |
AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma. |
2008 |
J Thorac Oncol |
pmid:18978557
|
Gray SG et al. |
Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells. |
2008 |
Clin Lung Cancer |
pmid:19073520
|
Chou CW and Chen CC |
HDAC inhibition upregulates the expression of angiostatic ADAMTS1. |
2008 |
FEBS Lett. |
pmid:19007777
|
Nair S et al. |
Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. |
2008 |
Pharm. Res. |
pmid:17657594
|
Setiadi AF et al. |
Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors. |
2008 |
Cancer Res. |
pmid:19047136
|
Mizumoto S et al. |
The developmental potential of parthenogenetic and somatic cell nuclear-transferred rat oocytes in vitro. |
2008 |
Cloning Stem Cells |
pmid:19049415
|
Slack MD et al. |
Characterizing heterogeneous cellular responses to perturbations. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19052231
|
Chittur SV et al. |
Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism. |
2008 |
BMC Genomics |
pmid:18959802
|
Hayashi K et al. |
Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. |
2008 |
Cell Stem Cell |
pmid:18940731
|
Ridolfi E et al. |
Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs. |
2008 |
Br. J. Cancer |
pmid:18941460
|
Cao W et al. |
Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling. |
2008 |
J. Exp. Med. |
pmid:18504304
|
Bigl M et al. |
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18938139
|
Zhang S et al. |
Effect of trichostatin a on viability and microRNA expression in human pancreatic cancer cell line BxPC-3. |
2008 |
Exp. Oncol. |
pmid:19112422
|
Kim TY et al. |
Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells. |
2008 |
Exp. Mol. Med. |
pmid:19116449
|
Jiang SJ et al. |
[Effects of trichostatin A and paclitaxel on apoptosis and microtubule stabilization in endometrial carcinoma cells: an in vitro research]. |
2008 |
Zhonghua Yi Xue Za Zhi |
pmid:19087722
|
Domingo-Domènech J et al. |
Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. |
2008 |
Breast Cancer Res. Treat. |
pmid:18064564
|
Hajji N et al. |
Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. |
2008 |
Oncogene |
pmid:18071312
|
Walton TJ et al. |
DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines. |
2008 |
Prostate |
pmid:18092350
|
Arany I et al. |
Restoration of CREB function ameliorates cisplatin cytotoxicity in renal tubular cells. |
2008 |
Am. J. Physiol. Renal Physiol. |
pmid:18094030
|
Jiemjit A et al. |
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. |
2008 |
Oncogene |
pmid:18223691
|
Nasu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model. |
2008 |
Osteoarthr. Cartil. |
pmid:18226559
|
Lim HG et al. |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. |
2008 |
Mol. Ther. |
pmid:18227841
|
Ruau D et al. |
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. |
2008 |
Stem Cells |
pmid:18203677
|
Chou SD and Tomasi TB |
Spatial distribution of histone methylation during MHC class II expression. |
2008 |
Mol. Immunol. |
pmid:17850872
|
Ragno R et al. |
Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies. |
2008 |
Eur J Med Chem |
pmid:17698257
|
Byers J and Eichinger D |
Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner. |
2008 |
Int. J. Parasitol. |
pmid:17706222
|
Fan J et al. |
ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. |
2008 |
J. Cancer Res. Clin. Oncol. |
pmid:18264725
|
Shi LH et al. |
Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos. |
2008 |
Dev. Dyn. |
pmid:18265023
|
Sasaki K et al. |
Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera. |
2008 |
Cancer Sci. |
pmid:18271940
|
Brown CR et al. |
Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. |
2008 |
Genes Dev. |
pmid:18316479
|
Fleury L et al. |
Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells. |
2008 |
Oncogene |
pmid:18317449
|
Muscolini M et al. |
Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells. |
2008 |
Mol. Cancer Ther. |
pmid:18566213
|
Fantini D et al. |
APE1/Ref-1 regulates PTEN expression mediated by Egr-1. |
2008 |
Free Radic. Res. |
pmid:18324520
|
Bieliauskas AV and Pflum MK |
Isoform-selective histone deacetylase inhibitors. |
2008 |
Chem Soc Rev |
pmid:18568166
|
Kang JH et al. |
CCAAT box is required for the induction of human thrombospondin-1 gene by trichostatin A. |
2008 |
J. Cell. Biochem. |
pmid:18275041
|
Zhang Y et al. |
Unlocking repression of the human luteinizing hormone receptor gene by trichostatin A-induced cell-specific phosphatase release. |
2008 |
J. Biol. Chem. |
pmid:18596044
|
Oliva J et al. |
Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. |
2008 |
Exp. Mol. Pathol. |
pmid:18280469
|
Xu LN et al. |
Effect of histone deacetylase inhibitor on proliferation of biliary tract cancer cell lines. |
2008 |
World J. Gastroenterol. |
pmid:18442209
|
Nakamura C et al. |
Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells. |
2008 |
Rheumatology (Oxford) |
pmid:18281366
|
Yu C et al. |
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. |
2008 |
Neuro-oncology |
pmid:18445700
|
Yu WP et al. |
Induction of ID1 expression and apoptosis by the histone deacetylase inhibitor (trichostatin A) in human acute myeloid leukaemic cells. |
2008 |
Cell Prolif. |
pmid:18211287
|
Jensen TJ et al. |
Epigenetic remodeling during arsenical-induced malignant transformation. |
2008 |
Carcinogenesis |
pmid:18448484
|
Kikuno N et al. |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. |
2008 |
Int. J. Cancer |
pmid:18431742
|
van West P et al. |
Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. |
2008 |
Microbiology (Reading, Engl.) |
pmid:18451057
|
Zhang HJ et al. |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. |
2008 |
Placenta |
pmid:18440631
|
Liu Z et al. |
Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. |
2008 |
Oncol. Rep. |
pmid:18575731
|
Meja KK et al. |
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. |
2008 |
Am. J. Respir. Cell Mol. Biol. |
pmid:18421014
|
Plouffe D et al. |
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18579783
|
Sun Y et al. |
Modulation of transcription parameters in glucocorticoid receptor-mediated repression. |
2008 |
Mol. Cell. Endocrinol. |
pmid:18583028
|
Tshuikina M et al. |
Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. |
2008 |
Exp. Hematol. |
pmid:18922617
|
Hishikawa K and Fujita T |
[Kidney regeneration update]. |
2008 |
Nippon Rinsho |
pmid:18464514
|
Wu X et al. |
Trichostatin A improved epigenetic modifications of transfected cells but did not improve subsequent cloned embryo development. |
2008 |
Anim. Biotechnol. |
pmid:18855246
|
Kato A et al. |
Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. |
2008 |
Exp. Cell Res. |
pmid:18588874
|
Li J et al. |
High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos. |
2008 |
Theriogenology |
pmid:18573521
|
Chen CJ et al. |
Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18590721
|
Ree AH et al. |
HDAC2 deficiency and histone acetylation. |
2008 |
Nat. Genet. |
pmid:18583969
|
Liu Y et al. |
Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. |
2008 |
Cancer Invest. |
pmid:18584348
|
Geli J et al. |
Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. |
2008 |
Int. J. Cancer |
pmid:18452173
|
Mazitschek R et al. |
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18430569
|
Habold C et al. |
Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. |
2008 |
J. Cell. Mol. Med. |
pmid:18419600
|
Romieu P et al. |
Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats. |
2008 |
J. Neurosci. |
pmid:18799668
|
Chan DW et al. |
Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells. |
2008 |
Int. J. Cancer |
pmid:18553387
|
Henkens T et al. |
Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes. |
2008 |
Toxicol. Lett. |
pmid:18358644
|
Wei Q et al. |
[Effect of trichostatin A on proliferation and interleukin-2 expression of mouse T cells in mixed lymphocyte culture]. |
2008 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:18359716
|
Svechnikova I et al. |
HDAC inhibitors effectively induce cell type-specific differentiation in human glioblastoma cell lines of different origin. |
2008 |
Int. J. Oncol. |
pmid:18360709
|
Mukherjee P et al. |
Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy. |
2008 |
Bioorg. Med. Chem. |
pmid:18362073
|
Fabre C et al. |
A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts. |
2008 |
Cell Cycle |
pmid:18641459
|
Brown SL et al. |
Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice. |
2008 |
Radiat. Res. |
pmid:18363436
|
Kozikowski AP et al. |
Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6. |
2008 |
J. Med. Chem. |
pmid:18642892
|
Vrbova G |
Spinal muscular atrophy: motoneurone or muscle disease? |
2008 |
Neuromuscul. Disord. |
pmid:18365338
|
Dow GS et al. |
Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors. |
2008 |
Antimicrob. Agents Chemother. |
pmid:18644969
|
Iager AE et al. |
Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos. |
2008 |
Cloning Stem Cells |
pmid:18419249
|
Liu PY et al. |
Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells. |
2008 |
Mol. Cancer Res. |
pmid:18644983
|
Liu TC et al. |
Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. |
2008 |
Mol. Ther. |
pmid:18388912
|
Roy S et al. |
Array-based analysis of the effects of trichostatin A and CG-1521 on cell cycle and cell death in LNCaP prostate cancer cells. |
2008 |
Mol. Cancer Ther. |
pmid:18645003
|
Hayakawa F et al. |
Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. |
2008 |
J. Biol. Chem. |
pmid:18621739
|
Reilly CM et al. |
The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. |
2008 |
J. Autoimmun. |
pmid:18650065
|
Law AY et al. |
Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. |
2008 |
Exp. Cell Res. |
pmid:18652825
|
Bosisio D et al. |
Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. |
2008 |
J. Leukoc. Biol. |
pmid:18780875
|
Yang L et al. |
[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. |
2008 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:18718068
|
Zou XM et al. |
Gastric cancer cell lines induced by trichostatin A. |
2008 |
World J. Gastroenterol. |
pmid:18720545
|
Nishino N et al. |
Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides. |
2008 |
Bioorg. Med. Chem. |
pmid:17900911
|
Duan H et al. |
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
2008 |
Oncogene |
pmid:18695675
|
Su RC et al. |
Epigenetic regulation of established human type 1 versus type 2 cytokine responses. |
2008 |
J. Allergy Clin. Immunol. |
pmid:17980413
|
Schauber J et al. |
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. |
2008 |
J. Invest. Dermatol. |
pmid:17943182
|
Chen J et al. |
Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis. |
2008 |
Chem. Biol. Interact. |
pmid:17961528
|
Carlisi D et al. |
Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. |
2008 |
Int. J. Oncol. |
pmid:18097557
|
Seo JS et al. |
Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A. |
2008 |
Oncol. Rep. |
pmid:18097580
|
Yeh JR et al. |
AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. |
2008 |
Development |
pmid:18156164
|
Jin B et al. |
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. |
2008 |
Hum. Mol. Genet. |
pmid:18029387
|
Gan Y et al. |
Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:17996726
|
Lee EJ et al. |
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
2008 |
Int. J. Oncol. |
pmid:18813790
|
Van Wagoner DR and Nattel S |
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18817781
|
Pellicciotta I et al. |
Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition. |
2008 |
Cancer Res. |
pmid:18829567
|
Hitchler MJ et al. |
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells. |
2008 |
Free Radic. Biol. Med. |
pmid:18845242
|