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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. |
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The mouse tumor cell lines EL4 and RMA display mosaic expression of NK-related and certain other surface molecules and appear to have a common origin. |
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IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a. |
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Cytokine |
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Cancer Res. |
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Cancer Res. |
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Endocrinology |
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The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
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The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase. |
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Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2. |
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Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1. |
2001 |
Biochem. Biophys. Res. Commun. |
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Regulation of the rat NHE3 gene promoter by sodium butyrate. |
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Am. J. Physiol. Gastrointest. Liver Physiol. |
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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. |
2001 |
Cancer Chemother. Pharmacol. |
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The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases. |
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Mol. Endocrinol. |
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Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. |
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Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. |
2001 |
Thyroid |
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Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. |
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The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. |
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Increased transcription levels induce higher mutation rates in a hypermutating cell line. |
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Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. |
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Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development. |
2001 |
Zygote |
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Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Nat. Cell Biol. |
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Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. |
2001 |
Cancer Res. |
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2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
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Isolation and sequencing of infectious clones of feline foamy virus and a human/feline foamy virus Env chimera. |
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J. Gen. Virol. |
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A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting. |
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J. Hum. Genet. |
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Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. |
2001 |
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