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ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. |
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DNA methylation regulates placental lactogen I gene expression. |
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Endocrinology |
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Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
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2001 |
Mol. Endocrinol. |
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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
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Functional knockout of the corepressor CtBP by the second exon of adenovirus E1a relieves repression of transcription. |
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Exp. Cell Res. |
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Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. |
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Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
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Mol. Cell. Biol. |
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Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
2001 |
Science |
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A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
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3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. |
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Evidence for gene silencing in Haemophilus influenzae. |
2001 |
Mutat. Res. |
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Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. |
2001 |
Cancer Res. |
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Position effects are influenced by the orientation of a transgene with respect to flanking chromatin. |
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Mol. Cell. Biol. |
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Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. |
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Biochem. J. |
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Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity. |
2001 |
Cancer Res. |
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DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. |
2001 |
Cancer Res. |
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Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. |
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EMBO J. |
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Loss of PU.1 expression following inhibition of histone deacetylases. |
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J. Immunol. |
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