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Probing lysine acetylation with a modification-specific marker ion using high-performance liquid chromatography/electrospray-mass spectrometry with collision-induced dissociation. |
2002 |
Anal. Chem. |
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Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. |
2002 |
Drug Metab. Dispos. |
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A chromosomal position effect on gene targeting in human cells. |
2002 |
Nucleic Acids Res. |
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Chicken HDAC2 down-regulates IgM light chain gene promoter activity. |
2002 |
Biochem. Biophys. Res. Commun. |
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Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor. |
2002 |
J. Hepatol. |
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Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. |
2002 |
Oncogene |
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Histone deacetylase activity is necessary for oligodendrocyte lineage progression. |
2002 |
J. Neurosci. |
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Role of histone deacetylation in developmentally programmed DNA rearrangements in Tetrahymena thermophila. |
2002 |
Eukaryotic Cell |
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Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster. |
2002 |
Arch. Biochem. Biophys. |
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Trichostatin A, a histone deacetylase inhibitor, down-regulates interleukin-12 transcription in SV-40-transformed lung epithelial cells. |
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Cell. Immunol. |
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Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen. |
2002 |
Mol. Cancer Ther. |
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The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. |
2003 |
J. Biol. Chem. |
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Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins. |
2002 |
Mol. Cancer Ther. |
pmid:12479699
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Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. |
2002 |
Mol. Cancer Ther. |
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Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. |
2003 |
Mol. Cell. Biol. |
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Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain. |
2003 |
Mol. Cell. Biol. |
pmid:12482978
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Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain. |
2002 |
Biochemistry |
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Constitutive repression of E2F1 transcriptional activity through HDAC proteins is essential for neuronal survival. |
2002 |
Ann. N. Y. Acad. Sci. |
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Evidence that the coactivator CBP/p300 is important for phenobarbital-induced but not basal expression of the CYP2H1 gene. |
2003 |
Mol. Pharmacol. |
pmid:12488538
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Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor. |
2002 |
Surgery |
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