| MeSH term | MeSH ID | Detail |
|---|---|---|
| Osteosarcoma | D012516 | 50 associated lipids |
| Brain Neoplasms | D001932 | 15 associated lipids |
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Muscular Dystrophies | D009136 | 10 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Intellectual Disability | D008607 | 13 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Prostatic Hyperplasia | D011470 | 20 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
trichostatin A
Trichostatin is a lipid of Polyketides (PK) class. Trichostatin is associated with abnormalities such as Dentatorubral-Pallidoluysian Atrophy, PARAGANGLIOMAS 3, abnormal fragmented structure, Disintegration (morphologic abnormality) and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Acetylation, Cell Differentiation process, histone modification, Gene Silencing and Transcriptional Activation. Trichostatin often locates in CD41a, Hematopoietic System, Chromatin Structure, Blood and Endothelium. The associated genes with Trichostatin are SPI1 gene, CELL Gene, Chromatin, CXCR4 gene and DNMT1 gene. The related lipids are Butyrates, Promega, butyrate, Lipopolysaccharides and Steroids. The related experimental models are Knock-out, Mouse Model, Xenograft Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of trichostatin A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with trichostatin A?
trichostatin A is suspected in Infection, Morphologically altered structure, Ureteral obstruction, Photosensitization, Atherosclerosis, Hypertrophic Cardiomyopathy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with trichostatin A
PubChem Associated disorders and diseases
What pathways are associated with trichostatin A
Lipid pathways are not clear in current pathway databases. We organized associated pathways with trichostatin A through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with trichostatin A?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with trichostatin A?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with trichostatin A?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with trichostatin A?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with trichostatin A?
Mouse Model
Mouse Model are used in the study 'Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer.' (Majid S et al., 2010), Mouse Model are used in the study 'Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.' (Fang MZ et al., 2005) and Mouse Model are used in the study 'Histone deacetylase 3 mediates allergic skin inflammation by regulating expression of MCP1 protein.' (Kim Y et al., 2012).
Xenograft Model
Xenograft Model are used in the study 'Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.' (Landreville S et al., 2012), Xenograft Model are used in the study 'Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.' (Moiseeva EP et al., 2007) and Xenograft Model are used in the study 'Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.' (Touma SE et al., 2005).
Cancer Model
Cancer Model are used in the study 'Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice.' (Sanderson L et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with trichostatin A
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Oger F et al. | The class I histone deacetylases of the platyhelminth parasite Schistosoma mansoni. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18977200 |
| Albertus DL et al. | AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma. | 2008 | J Thorac Oncol | pmid:18978557 |
| Ridolfi E et al. | Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs. | 2008 | Br. J. Cancer | pmid:18941460 |
| Cao W et al. | Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling. | 2008 | J. Exp. Med. | pmid:18504304 |
| Bigl M et al. | Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18938139 |
| Golyshev SA et al. | [The role of DNA methylation and histone modifications in structural maintainance of heterochromatin domains (chromocenters)]. | 2008 | Tsitologiia | pmid:19140344 |
| Zhou Q et al. | Histone deacetylase inhibitors blocked activation and caused senescence of corneal stromal cells. | 2008 | Mol. Vis. | pmid:19122829 |
| Zhang S et al. | Effect of trichostatin a on viability and microRNA expression in human pancreatic cancer cell line BxPC-3. | 2008 | Exp. Oncol. | pmid:19112422 |
| Kim TY et al. | Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells. | 2008 | Exp. Mol. Med. | pmid:19116449 |
| Jiang SJ et al. | [Effects of trichostatin A and paclitaxel on apoptosis and microtubule stabilization in endometrial carcinoma cells: an in vitro research]. | 2008 | Zhonghua Yi Xue Za Zhi | pmid:19087722 |
| Khan AN et al. | Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells. | 2008 | Cancer Immunol. Immunother. | pmid:18046553 |
| Domingo-Domènech J et al. | Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. | 2008 | Breast Cancer Res. Treat. | pmid:18064564 |
| Hajji N et al. | Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. | 2008 | Oncogene | pmid:18071312 |
| Walton TJ et al. | DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines. | 2008 | Prostate | pmid:18092350 |
| Arany I et al. | Restoration of CREB function ameliorates cisplatin cytotoxicity in renal tubular cells. | 2008 | Am. J. Physiol. Renal Physiol. | pmid:18094030 |
| Jiemjit A et al. | p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. | 2008 | Oncogene | pmid:18223691 |
| Heller G et al. | Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells. | 2008 | Cancer Res. | pmid:18172295 |
| Yildirim F et al. | Inhibition of histone deacetylation protects wildtype but not gelsolin-deficient mice from ischemic brain injury. | 2008 | Exp. Neurol. | pmid:18234195 |
| Tang Y et al. | Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site. | 2008 | Circ. Res. | pmid:18239137 |
| Wang Q et al. | The spatial relationship between heterochromatin protein 1 alpha and histone modifications during mouse oocyte meiosis. | 2008 | Cell Cycle | pmid:18239470 |
| Li X et al. | The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts. | 2008 | Cloning Stem Cells | pmid:18241125 |
| Chou SD and Tomasi TB | Spatial distribution of histone methylation during MHC class II expression. | 2008 | Mol. Immunol. | pmid:17850872 |
| Ragno R et al. | Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies. | 2008 | Eur J Med Chem | pmid:17698257 |
| Byers J and Eichinger D | Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner. | 2008 | Int. J. Parasitol. | pmid:17706222 |
| Kim M et al. | Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion. | 2008 | Mol. Cancer Res. | pmid:18314483 |
| Schuetz A et al. | Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. | 2008 | J. Biol. Chem. | pmid:18285338 |
| Horswill MA et al. | Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. | 2008 | Exp. Eye Res. | pmid:18291368 |
| Countryman JK et al. | Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virus-infected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors. | 2008 | J. Virol. | pmid:18337569 |
| Borghol N et al. | Transcriptional and epigenetic status of protamine 1 and 2 genes following round spermatids injection into mouse oocytes. | 2008 | Genomics | pmid:18343090 |
| Hoffmann K et al. | Increase in antiepileptic efficacy during prolonged treatment with valproic acid: role of inhibition of histone deacetylases? | 2008 | Epilepsy Res. | pmid:18538545 |
| Lin W et al. | Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40. | 2008 | Genes Cells | pmid:18298800 |
| Jiang X et al. | DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. | 2008 | Cancer Cell | pmid:18538736 |
| Fan J et al. | ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. | 2008 | J. Cancer Res. Clin. Oncol. | pmid:18264725 |
| Gavin DP et al. | Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects. | 2008 | Schizophr. Res. | pmid:18539439 |
| Shi LH et al. | Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos. | 2008 | Dev. Dyn. | pmid:18265023 |
| Lecona E et al. | Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase. | 2008 | Mol. Cell. Biol. | pmid:18541673 |
| Sasaki K et al. | Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera. | 2008 | Cancer Sci. | pmid:18271940 |
| Moynihan AT et al. | Histone deacetylase inhibitors and a functional potent inhibitory effect on human uterine contractility. | 2008 | Am. J. Obstet. Gynecol. | pmid:18455134 |
| Brown CR et al. | Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. | 2008 | Genes Dev. | pmid:18316479 |
| Mackay CL et al. | Sensitive, specific, and quantitative FTICR mass spectrometry of combinatorial post-translational modifications in intact histone H4. | 2008 | Anal. Chem. | pmid:18457408 |
| Fleury L et al. | Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells. | 2008 | Oncogene | pmid:18317449 |
| Muscolini M et al. | Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells. | 2008 | Mol. Cancer Ther. | pmid:18566213 |
| Fantini D et al. | APE1/Ref-1 regulates PTEN expression mediated by Egr-1. | 2008 | Free Radic. Res. | pmid:18324520 |
| Bieliauskas AV and Pflum MK | Isoform-selective histone deacetylase inhibitors. | 2008 | Chem Soc Rev | pmid:18568166 |
| Kang JH et al. | CCAAT box is required for the induction of human thrombospondin-1 gene by trichostatin A. | 2008 | J. Cell. Biochem. | pmid:18275041 |
| Zhang Y et al. | Unlocking repression of the human luteinizing hormone receptor gene by trichostatin A-induced cell-specific phosphatase release. | 2008 | J. Biol. Chem. | pmid:18596044 |
| Oliva J et al. | Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. | 2008 | Exp. Mol. Pathol. | pmid:18280469 |
| Xu LN et al. | Effect of histone deacetylase inhibitor on proliferation of biliary tract cancer cell lines. | 2008 | World J. Gastroenterol. | pmid:18442209 |
| Nakamura C et al. | Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells. | 2008 | Rheumatology (Oxford) | pmid:18281366 |
| Yu C et al. | Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. | 2008 | Neuro-oncology | pmid:18445700 |
| Jensen TJ et al. | Epigenetic remodeling during arsenical-induced malignant transformation. | 2008 | Carcinogenesis | pmid:18448484 |
| van West P et al. | Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. | 2008 | Microbiology (Reading, Engl.) | pmid:18451057 |
| Liu Z et al. | Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. | 2008 | Oncol. Rep. | pmid:18575731 |
| Plouffe D et al. | In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18579783 |
| Romieu P et al. | Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats. | 2008 | J. Neurosci. | pmid:18799668 |
| Chan DW et al. | Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells. | 2008 | Int. J. Cancer | pmid:18553387 |
| Kawamoto K et al. | DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines. | 2008 | Int. J. Cancer | pmid:18404682 |
| Kaipparettu BA et al. | Estrogen-mediated downregulation of CD24 in breast cancer cells. | 2008 | Int. J. Cancer | pmid:18404683 |
| Jeseta M et al. | In vitro ageing of pig oocytes: effects of the histone deacetylase inhibitor trichostatin A. | 2008 | Zygote | pmid:18405435 |
| Lin YC et al. | Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2. | 2008 | Cancer Res. | pmid:18381445 |
| Pandey SC et al. | Brain chromatin remodeling: a novel mechanism of alcoholism. | 2008 | J. Neurosci. | pmid:18385331 |
| Chu F et al. | Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway. | 2008 | Aging Cell | pmid:18489729 |
| Rebbaa A et al. | Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent. | 2008 | Angiogenesis | pmid:18386142 |
| Wu JY et al. | Enhancement of glutamate uptake in 1-methyl-4-phenylpyridinium-treated astrocytes by trichostatin A. | 2008 | Neuroreport | pmid:18628666 |
| Henkens T et al. | Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes. | 2008 | Toxicol. Lett. | pmid:18358644 |
| Shakèd M et al. | Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. | 2008 | PLoS ONE | pmid:18628975 |
| Wei Q et al. | [Effect of trichostatin A on proliferation and interleukin-2 expression of mouse T cells in mixed lymphocyte culture]. | 2008 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:18359716 |
| Hämäläinen M et al. | Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors. | 2008 | Pulm Pharmacol Ther | pmid:17913526 |
| Svechnikova I et al. | HDAC inhibitors effectively induce cell type-specific differentiation in human glioblastoma cell lines of different origin. | 2008 | Int. J. Oncol. | pmid:18360709 |
| Fontán-Lozano A et al. | Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice. | 2008 | Mol. Cell. Neurosci. | pmid:18638560 |
| Mukherjee P et al. | Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy. | 2008 | Bioorg. Med. Chem. | pmid:18362073 |
| Fabre C et al. | A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts. | 2008 | Cell Cycle | pmid:18641459 |
| Pryzbylkowski P et al. | Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. | 2008 | Breast Cancer Res. Treat. | pmid:17891453 |
| Brown SL et al. | Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice. | 2008 | Radiat. Res. | pmid:18363436 |
| Kozikowski AP et al. | Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6. | 2008 | J. Med. Chem. | pmid:18642892 |
| Vrbova G | Spinal muscular atrophy: motoneurone or muscle disease? | 2008 | Neuromuscul. Disord. | pmid:18365338 |
| Dow GS et al. | Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors. | 2008 | Antimicrob. Agents Chemother. | pmid:18644969 |
| Iager AE et al. | Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos. | 2008 | Cloning Stem Cells | pmid:18419249 |
| Liu PY et al. | Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells. | 2008 | Mol. Cancer Res. | pmid:18644983 |
| Liu TC et al. | Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. | 2008 | Mol. Ther. | pmid:18388912 |
| Roy S et al. | Array-based analysis of the effects of trichostatin A and CG-1521 on cell cycle and cell death in LNCaP prostate cancer cells. | 2008 | Mol. Cancer Ther. | pmid:18645003 |
| Hayakawa F et al. | Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. | 2008 | J. Biol. Chem. | pmid:18621739 |
| Reilly CM et al. | The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. | 2008 | J. Autoimmun. | pmid:18650065 |
| Law AY et al. | Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. | 2008 | Exp. Cell Res. | pmid:18652825 |
| Bosisio D et al. | Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. | 2008 | J. Leukoc. Biol. | pmid:18780875 |
| Yang L et al. | [Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. | 2008 | Zhongguo Shi Yan Xue Ye Xue Za Zhi | pmid:18718068 |
| Schauber J et al. | Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. | 2008 | J. Invest. Dermatol. | pmid:17943182 |
| Chen J et al. | Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis. | 2008 | Chem. Biol. Interact. | pmid:17961528 |
| Kim M et al. | LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer. | 2008 | Cancer Res. | pmid:18757430 |
| Ma Y et al. | Inhibition of protein deacetylation by trichostatin A impairs microtubule-kinetochore attachment. | 2008 | Cell. Mol. Life Sci. | pmid:18759129 |
| Zhang Y et al. | Pro-IL-16 recruits histone deacetylase 3 to the Skp2 core promoter through interaction with transcription factor GABP. | 2008 | J. Immunol. | pmid:18097041 |
| Carlisi D et al. | Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. | 2008 | Int. J. Oncol. | pmid:18097557 |
| Seo JS et al. | Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A. | 2008 | Oncol. Rep. | pmid:18097580 |
| Yeh JR et al. | AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. | 2008 | Development | pmid:18156164 |
| Liu F et al. | Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. | 2008 | J. Mol. Cell. Cardiol. | pmid:18926829 |
| Wu Y and Guo SW | Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells. | 2008 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:17376583 |
| Jin B et al. | DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. | 2008 | Hum. Mol. Genet. | pmid:18029387 |
| Gan Y et al. | Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. | 2008 | Biochem. Biophys. Res. Commun. | pmid:17996726 |
| Lee EJ et al. | Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. | 2008 | Int. J. Oncol. | pmid:18813790 |
| Van Wagoner DR and Nattel S | Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. | 2008 | J. Mol. Cell. Cardiol. | pmid:18817781 |