Marengo E et al. |
Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. |
2008 |
J. Proteome Res. |
pmid:18543959
|
Lecona E et al. |
Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase. |
2008 |
Mol. Cell. Biol. |
pmid:18541673
|
Gavin DP et al. |
Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects. |
2008 |
Schizophr. Res. |
pmid:18539439
|
Jiang X et al. |
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. |
2008 |
Cancer Cell |
pmid:18538736
|
Hoffmann K et al. |
Increase in antiepileptic efficacy during prolonged treatment with valproic acid: role of inhibition of histone deacetylases? |
2008 |
Epilepsy Res. |
pmid:18538545
|
Makki MS et al. |
TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels. |
2008 |
Nucleic Acids Res. |
pmid:18535006
|
Chung KS et al. |
Fission yeast-based screening to identify putative HDAC inhibitors using a telomeric reporter strain. |
2008 |
Mol. Cells |
pmid:18525239
|
Hou J et al. |
Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation. |
2008 |
BMC Dev. Biol. |
pmid:18507869
|
Pan J et al. |
TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. |
2008 |
Mol. Cancer Res. |
pmid:18505930
|
Cao W et al. |
Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling. |
2008 |
J. Exp. Med. |
pmid:18504304
|
Ma P and Schultz RM |
Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos. |
2008 |
Dev. Biol. |
pmid:18501342
|
Sun C and Zhou J |
Trichostatin A improves insulin stimulated glucose utilization and insulin signaling transduction through the repression of HDAC2. |
2008 |
Biochem. Pharmacol. |
pmid:18495085
|
Chen Y et al. |
A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum. |
2008 |
J. Med. Chem. |
pmid:18494463
|
Chu F et al. |
Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway. |
2008 |
Aging Cell |
pmid:18489729
|
Egler V et al. |
Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death. |
2008 |
Clin. Cancer Res. |
pmid:18483381
|
Dalgard CL et al. |
Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma. |
2008 |
Clin. Cancer Res. |
pmid:18483379
|
Hishikawa K and Fujita T |
[Kidney regeneration update]. |
2008 |
Nippon Rinsho |
pmid:18464514
|
Mackay CL et al. |
Sensitive, specific, and quantitative FTICR mass spectrometry of combinatorial post-translational modifications in intact histone H4. |
2008 |
Anal. Chem. |
pmid:18457408
|
Moynihan AT et al. |
Histone deacetylase inhibitors and a functional potent inhibitory effect on human uterine contractility. |
2008 |
Am. J. Obstet. Gynecol. |
pmid:18455134
|
Geli J et al. |
Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. |
2008 |
Int. J. Cancer |
pmid:18452173
|
van West P et al. |
Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. |
2008 |
Microbiology (Reading, Engl.) |
pmid:18451057
|
Jensen TJ et al. |
Epigenetic remodeling during arsenical-induced malignant transformation. |
2008 |
Carcinogenesis |
pmid:18448484
|
Yu C et al. |
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. |
2008 |
Neuro-oncology |
pmid:18445700
|
Xu LN et al. |
Effect of histone deacetylase inhibitor on proliferation of biliary tract cancer cell lines. |
2008 |
World J. Gastroenterol. |
pmid:18442209
|
Zhang HJ et al. |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. |
2008 |
Placenta |
pmid:18440631
|
Kikuno N et al. |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. |
2008 |
Int. J. Cancer |
pmid:18431742
|
Mazitschek R et al. |
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18430569
|
Sebastián C et al. |
Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells. |
2008 |
J. Immunol. |
pmid:18424709
|
Meja KK et al. |
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. |
2008 |
Am. J. Respir. Cell Mol. Biol. |
pmid:18421014
|
Habold C et al. |
Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. |
2008 |
J. Cell. Mol. Med. |
pmid:18419600
|
Iager AE et al. |
Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos. |
2008 |
Cloning Stem Cells |
pmid:18419249
|
Jeseta M et al. |
In vitro ageing of pig oocytes: effects of the histone deacetylase inhibitor trichostatin A. |
2008 |
Zygote |
pmid:18405435
|
Kaipparettu BA et al. |
Estrogen-mediated downregulation of CD24 in breast cancer cells. |
2008 |
Int. J. Cancer |
pmid:18404683
|
Kawamoto K et al. |
DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines. |
2008 |
Int. J. Cancer |
pmid:18404682
|
Roy S et al. |
Histone deacetylase 5 represses the transcription of cyclin D3. |
2008 |
J. Cell. Biochem. |
pmid:18404677
|
Ko JM et al. |
Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma. |
2008 |
Mol. Cancer Res. |
pmid:18403638
|
Yan C et al. |
Comparative molecular dynamics simulations of histone deacetylase-like protein: binding modes and free energy analysis to hydroxamic acid inhibitors. |
2008 |
Proteins |
pmid:18398905
|
Chen PC et al. |
Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group. |
2008 |
Bioorg. Med. Chem. |
pmid:18397827
|
Nakao Y et al. |
Evaluation of antiangiogenic activity of azumamides by the in vitro vascular organization model using mouse induced pluripotent stem (iPS) cells. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18397826
|
Qi J et al. |
[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. |
2007 |
Zhonghua Zhong Liu Za Zhi |
pmid:18396643
|
Galiová G et al. |
Chromatin changes induced by lamin A/C deficiency and the histone deacetylase inhibitor trichostatin A. |
2008 |
Eur. J. Cell Biol. |
pmid:18396346
|
Karantzali E et al. |
Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis. |
2008 |
Genome Biol. |
pmid:18394158
|
Liu TC et al. |
Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. |
2008 |
Mol. Ther. |
pmid:18388912
|
Rebbaa A et al. |
Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent. |
2008 |
Angiogenesis |
pmid:18386142
|
Pandey SC et al. |
Brain chromatin remodeling: a novel mechanism of alcoholism. |
2008 |
J. Neurosci. |
pmid:18385331
|
Lin YC et al. |
Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2. |
2008 |
Cancer Res. |
pmid:18381445
|
Xu ZM et al. |
The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage. |
2008 |
BMB Rep |
pmid:18377727
|
Lindström TM et al. |
Histone deacetylase inhibitors exert time-dependent effects on nuclear factor-kappaB but consistently suppress the expression of proinflammatory genes in human myometrial cells. |
2008 |
Mol. Pharmacol. |
pmid:18375836
|
Biacsi R et al. |
SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. |
2008 |
PLoS Genet. |
pmid:18369442
|
Vrbova G |
Spinal muscular atrophy: motoneurone or muscle disease? |
2008 |
Neuromuscul. Disord. |
pmid:18365338
|
Brown SL et al. |
Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice. |
2008 |
Radiat. Res. |
pmid:18363436
|
Mukherjee P et al. |
Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy. |
2008 |
Bioorg. Med. Chem. |
pmid:18362073
|
Svechnikova I et al. |
HDAC inhibitors effectively induce cell type-specific differentiation in human glioblastoma cell lines of different origin. |
2008 |
Int. J. Oncol. |
pmid:18360709
|
Wei Q et al. |
[Effect of trichostatin A on proliferation and interleukin-2 expression of mouse T cells in mixed lymphocyte culture]. |
2008 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:18359716
|
Henkens T et al. |
Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes. |
2008 |
Toxicol. Lett. |
pmid:18358644
|
Kimata Y et al. |
Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin. |
2008 |
J. Cell. Sci. |
pmid:18354085
|
Balakrishnan L and Milavetz B |
HDAC inhibitors stimulate viral transcription by multiple mechanisms. |
2008 |
Virol. J. |
pmid:18353181
|
Borghol N et al. |
Transcriptional and epigenetic status of protamine 1 and 2 genes following round spermatids injection into mouse oocytes. |
2008 |
Genomics |
pmid:18343090
|
Countryman JK et al. |
Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virus-infected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors. |
2008 |
J. Virol. |
pmid:18337569
|
Fantini D et al. |
APE1/Ref-1 regulates PTEN expression mediated by Egr-1. |
2008 |
Free Radic. Res. |
pmid:18324520
|
Fleury L et al. |
Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells. |
2008 |
Oncogene |
pmid:18317449
|
Brown CR et al. |
Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. |
2008 |
Genes Dev. |
pmid:18316479
|
Kim M et al. |
Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion. |
2008 |
Mol. Cancer Res. |
pmid:18314483
|
Dong G et al. |
Induction of apoptosis in renal tubular cells by histone deacetylase inhibitors, a family of anticancer agents. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:18310471
|
Jiang Y et al. |
Homocysteine-induced extracellular superoxide dismutase and its epigenetic mechanisms in monocytes. |
2008 |
J. Exp. Biol. |
pmid:18310117
|
Suuronen T et al. |
Regulation of ER alpha signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90. |
2008 |
Neurochem. Res. |
pmid:18307035
|
Lin W et al. |
Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40. |
2008 |
Genes Cells |
pmid:18298800
|
Horswill MA et al. |
Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. |
2008 |
Exp. Eye Res. |
pmid:18291368
|
Schuetz A et al. |
Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. |
2008 |
J. Biol. Chem. |
pmid:18285338
|
Nakamura C et al. |
Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells. |
2008 |
Rheumatology (Oxford) |
pmid:18281366
|
Oliva J et al. |
Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. |
2008 |
Exp. Mol. Pathol. |
pmid:18280469
|
Kovács P et al. |
Effect of histone deacetylase inhibitor trichostatin A (TSA) on the microtubular system of Tetrahymena. |
2007 |
Acta. Biol. Hung. |
pmid:18277464
|
Kang JH et al. |
CCAAT box is required for the induction of human thrombospondin-1 gene by trichostatin A. |
2008 |
J. Cell. Biochem. |
pmid:18275041
|
Sasaki K et al. |
Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera. |
2008 |
Cancer Sci. |
pmid:18271940
|
Shi LH et al. |
Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos. |
2008 |
Dev. Dyn. |
pmid:18265023
|
Fan J et al. |
ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. |
2008 |
J. Cancer Res. Clin. Oncol. |
pmid:18264725
|
Politis PK et al. |
BM88/Cend1 is involved in histone deacetylase inhibition-mediated growth arrest and differentiation of neuroblastoma cells. |
2008 |
FEBS Lett. |
pmid:18258204
|
Mazzarelli P et al. |
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation? |
2007 |
Cancer Biol. Ther. |
pmid:18253084
|
Gupta MP et al. |
HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity. |
2008 |
J. Biol. Chem. |
pmid:18250163
|
Paris M et al. |
Histone deacetylase inhibitors: from bench to clinic. |
2008 |
J. Med. Chem. |
pmid:18247554
|
Shi LH et al. |
Trichostatin A and nuclear reprogramming of cloned rabbit embryos. |
2008 |
J. Anim. Sci. |
pmid:18245503
|
Li X et al. |
The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts. |
2008 |
Cloning Stem Cells |
pmid:18241125
|
Wang Q et al. |
The spatial relationship between heterochromatin protein 1 alpha and histone modifications during mouse oocyte meiosis. |
2008 |
Cell Cycle |
pmid:18239470
|
Tang Y et al. |
Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site. |
2008 |
Circ. Res. |
pmid:18239137
|
Yildirim F et al. |
Inhibition of histone deacetylation protects wildtype but not gelsolin-deficient mice from ischemic brain injury. |
2008 |
Exp. Neurol. |
pmid:18234195
|
Lim HG et al. |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. |
2008 |
Mol. Ther. |
pmid:18227841
|
Nasu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model. |
2008 |
Osteoarthr. Cartil. |
pmid:18226559
|
Kuwajima A et al. |
The histone deacetylase inhibitor butyrate inhibits melanoma cell invasion of Matrigel. |
2007 Nov-Dec |
Anticancer Res. |
pmid:18225587
|
Yasuda K et al. |
ERas oncogene expression and epigenetic regulation by histone acetylation in human cancer cells. |
2007 Nov-Dec |
Anticancer Res. |
pmid:18225573
|
Jiemjit A et al. |
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. |
2008 |
Oncogene |
pmid:18223691
|
Andrews KT et al. |
Potent antimalarial activity of histone deacetylase inhibitor analogues. |
2008 |
Antimicrob. Agents Chemother. |
pmid:18212103
|
Yu WP et al. |
Induction of ID1 expression and apoptosis by the histone deacetylase inhibitor (trichostatin A) in human acute myeloid leukaemic cells. |
2008 |
Cell Prolif. |
pmid:18211287
|
Duhamel M et al. |
Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. |
2008 |
FEBS Lett. |
pmid:18206652
|
Hamner JB et al. |
The efficacy of combination therapy using adeno-associated virus--interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma. |
2008 |
J. Pediatr. Surg. |
pmid:18206478
|
Serrano E et al. |
Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. |
2008 |
Leuk. Res. |
pmid:18206229
|
Ruau D et al. |
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. |
2008 |
Stem Cells |
pmid:18203677
|
Isakov E et al. |
Trichostatin A regulates peroxiredoxin expression and virulence of the parasite Entamoeba histolytica. |
2008 |
Mol. Biochem. Parasitol. |
pmid:18191469
|
Heller G et al. |
Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells. |
2008 |
Cancer Res. |
pmid:18172295
|
Wu ZQ et al. |
Histone deacetylase inhibitor trichostatin A induced caspase-independent apoptosis in human gastric cancer cell. |
2007 |
Chin. Med. J. |
pmid:18167185
|
Joseph RA et al. |
Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. |
2008 |
Hepatology |
pmid:18161881
|