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Biochemistry |
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Clin Lung Cancer |
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Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. |
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Oncogene |
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Oncogene |
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DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines. |
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Prostate |
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Restoration of CREB function ameliorates cisplatin cytotoxicity in renal tubular cells. |
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Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model. |
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Hepatology |
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Mol. Immunol. |
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Oncogene |
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Immunology |
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Oncogene |
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Carcinogenesis |
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Microbiology (Reading, Engl.) |
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Placenta |
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Mol. Cancer |
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Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors. |
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Pulm Pharmacol Ther |
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Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy. |
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Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice. |
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Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos. |
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Cloning Stem Cells |
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The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. |
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Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. |
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[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. |
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Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
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Oncogene |
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Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. |
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Theriogenology |
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Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death. |
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Pharmazie |
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Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition. |
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Ann. Neurol. |
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Oncol. Rep. |
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AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. |
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Development |
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Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. |
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J. Mol. Cell. Cardiol. |
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Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas. |
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Genes Genet. Syst. |
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Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
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Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells. |
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Eur. J. Obstet. Gynecol. Reprod. Biol. |
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DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. |
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Hum. Mol. Genet. |
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Biochem. Biophys. Res. Commun. |
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[Effects of trichostatin A on the interaction between HBx and histone deacetylase protein 1]. |
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Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
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Int. J. Oncol. |
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Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
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Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition. |
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Cancer Res. |
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