Hobbs CA and Gilmour SK |
High levels of intracellular polyamines promote histone acetyltransferase activity resulting in chromatin hyperacetylation. |
2000 |
J. Cell. Biochem. |
pmid:10760944
|
Yoshida M and Horinouchi S |
[Histone deacetylase inhibitors--new anticancer agents?]. |
2000 |
Tanpakushitsu Kakusan Koso |
pmid:10771678
|
Yu F et al. |
Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2. |
2000 |
Nucleic Acids Res. |
pmid:10773092
|
Kitamura K et al. |
Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all-trans retinoic acid. |
2000 |
Br. J. Haematol. |
pmid:10792271
|
Saleh M et al. |
Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases. |
2000 |
Mol. Cell. Biol. |
pmid:11046157
|
Diamond SE and Gutierrez-Hartmann A |
The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter. |
2000 |
J. Biol. Chem. |
pmid:10921928
|
Andoh A et al. |
Modulation of complement component (C3 and factor B) biosynthesis by a histone deacetylase inhibitor in human intestinal epithelial cells. |
2000 |
Int. J. Mol. Med. |
pmid:10851266
|
Siavoshian S et al. |
Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression. |
2000 |
Gut |
pmid:10716680
|
Jin S et al. |
Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10841572
|
Claassen GF and Hann SR |
A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10920185
|
Mao C and Shapiro DJ |
A histone deacetylase inhibitor potentiates estrogen receptor activation of a stably integrated vitellogenin promoter in HepG2 cells. |
2000 |
Endocrinology |
pmid:10875235
|
Clayton AL et al. |
Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation. |
2000 |
EMBO J. |
pmid:10899125
|
Kang J et al. |
Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetases. |
2000 |
J. Biol. Chem. |
pmid:10913161
|
Yu J et al. |
Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. |
2000 |
Mol. Cell. Biol. |
pmid:10713181
|
Adachi N et al. |
Cell-cycle regulation of the DNA topoisomerase IIalpha promoter is mediated by proximal CCAAT boxes: possible involvement of acetylation. |
2000 |
Gene |
pmid:10713444
|
Shin JY et al. |
Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells. |
2000 |
Cancer Res. |
pmid:10667572
|
Hodny Z et al. |
Sp1 and chromatin environment are important contributors to the formation of repressive chromatin structures on the transfected human adenine nucleotide translocase-2 promoter. |
2000 |
Biochem. J. |
pmid:10657244
|
Garrison PM et al. |
Effects of histone deacetylase inhibitors on the Ah receptor gene promoter. |
2000 |
Arch. Biochem. Biophys. |
pmid:10666294
|
Smith RD et al. |
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. |
2000 |
Blood |
pmid:10648397
|
Dressel U et al. |
Promoter specific sensitivity to inhibition of histone deacetylases: implications for hormonal gene control, cellular differentiation and cancer. |
2000 Mar-Apr |
Anticancer Res. |
pmid:10810390
|
Steinbac OC et al. |
Histone deacetylase activity is required for the induction of the MyoD muscle cell lineage in Xenopus. |
2000 Sep-Oct |
Biol. Chem. |
pmid:11076034
|
Amin HM et al. |
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). |
2001 |
Br. J. Haematol. |
pmid:11703323
|
Pile LA et al. |
The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
2001 |
Cell. Mol. Life Sci. |
pmid:11706997
|
Sachs LM et al. |
An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. |
2001 |
Int. J. Mol. Med. |
pmid:11712071
|
Lefevre P et al. |
Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
2001 |
Nucleic Acids Res. |
pmid:11713304
|
Sekita N et al. |
Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. |
2001 |
Jpn. J. Cancer Res. |
pmid:11572762
|
Yin L et al. |
Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. |
2001 |
J. Biol. Chem. |
pmid:11572859
|
Leng SL et al. |
Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. |
2001 |
Carcinogenesis |
pmid:11577001
|
Yang X et al. |
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. |
2001 |
Cancer Res. |
pmid:11585728
|
Abderrahmani A et al. |
The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). |
2001 |
Mol. Cell. Biol. |
pmid:11585908
|
Yoshida M et al. |
Histone deacetylase as a new target for cancer chemotherapy. |
2001 |
Cancer Chemother. Pharmacol. |
pmid:11587361
|
Jung M |
Inhibitors of histone deacetylase as new anticancer agents. |
2001 |
Curr. Med. Chem. |
pmid:11562279
|
Ashburner BP et al. |
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. |
2001 |
Mol. Cell. Biol. |
pmid:11564889
|
Sachs LM et al. |
Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis. |
2001 |
Dev. Dyn. |
pmid:11668605
|
Amann JM et al. |
ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. |
2001 |
Mol. Cell. Biol. |
pmid:11533236
|
Plant KE et al. |
Intergenic transcription in the human beta-globin gene cluster. |
2001 |
Mol. Cell. Biol. |
pmid:11533239
|
Chen Lf W et al. |
Duration of nuclear NF-kappaB action regulated by reversible acetylation. |
2001 |
Science |
pmid:11533489
|
Vinatzer U et al. |
The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase. |
2001 |
Br. J. Haematol. |
pmid:11552981
|
Cho JH et al. |
DNA methylation regulates placental lactogen I gene expression. |
2001 |
Endocrinology |
pmid:11459782
|
Walker GE et al. |
Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
pmid:11517158
|
Jorgensen JS and Nilson JH |
AR suppresses transcription of the alpha glycoprotein hormone subunit gene through protein-protein interactions with cJun and activation transcription factor 2. |
2001 |
Mol. Endocrinol. |
pmid:11518798
|
Phiel CJ et al. |
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
2001 |
J. Biol. Chem. |
pmid:11473107
|
Sundqvist A et al. |
Functional knockout of the corepressor CtBP by the second exon of adenovirus E1a relieves repression of transcription. |
2001 |
Exp. Cell Res. |
pmid:11478854
|
Jacob AL et al. |
Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. |
2001 |
J. Biol. Chem. |
pmid:11479297
|
Sourlingas TG et al. |
Histone deacetylase inhibitors induce apoptosis in peripheral blood lymphocytes along with histone H4 acetylation and the expression of the linker histone variant, H1 degrees. |
2001 |
Eur. J. Cell Biol. |
pmid:11824792
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. |
2001 |
Brain Tumor Pathol |
pmid:11908866
|
Benjamin D and Jost JP |
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
pmid:11522830
|
Li J et al. |
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
2001 |
Mol. Cell. Biol. |
pmid:11689710
|
Hirschler-Laszkiewicz I et al. |
The role of acetylation in rDNA transcription. |
2001 |
Nucleic Acids Res. |
pmid:11600700
|
Nair AR et al. |
Paradoxical effects of trichostatin A: inhibition of NF-Y-associated histone acetyltransferase activity, phosphorylation of hGCN5 and downregulation of cyclin A and B1 mRNA. |
2001 |
Cancer Lett. |
pmid:11295287
|
Hatama S et al. |
Reactivation of feline foamy virus from a chronically infected feline renal cell line by trichostatin A. |
2001 |
Virology |
pmid:11336556
|
Viollet B et al. |
Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1alpha (HNF1alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1alpha-deficient hepatocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11340160
|
Nakamura M et al. |
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor. |
2001 |
J. Cell. Physiol. |
pmid:11319763
|
Xu D et al. |
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11274400
|
Seth KA and Majzoub JA |
Repressor element silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) can act as an enhancer as well as a repressor of corticotropin-releasing hormone gene transcription. |
2001 |
J. Biol. Chem. |
pmid:11278361
|
Matsuda E et al. |
Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms. |
2001 |
J. Biol. Chem. |
pmid:11278721
|
Kim MS et al. |
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. |
2001 |
Nat. Med. |
pmid:11283670
|
Vigushin DM et al. |
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. |
2001 |
Clin. Cancer Res. |
pmid:11309348
|
Magdinier F and Wolffe AP |
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11309512
|
Grande A et al. |
A functionally active RARalpha nuclear receptor is expressed in retinoic acid non responsive early myeloblastic cell lines. |
2001 |
Cell Death Differ. |
pmid:11313705
|
Wu Y et al. |
Negative regulation of bcl-2 expression by p53 in hematopoietic cells. |
2001 |
Oncogene |
pmid:11313951
|
Greenberg VL et al. |
Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. |
2001 |
Thyroid |
pmid:11349829
|
Lea MA et al. |
Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. |
2001 |
Int. J. Cancer |
pmid:11351296
|
Rashid SF et al. |
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
2001 |
Oncogene |
pmid:11313934
|
Maës J et al. |
Chromatin remodeling at the Ig loci prior to V(D)J recombination. |
2001 |
J. Immunol. |
pmid:11441093
|
Wang H et al. |
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
2001 |
Science |
pmid:11387442
|
Klar AJ et al. |
A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
pmid:11404352
|
Massa S et al. |
3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. |
2001 |
J. Med. Chem. |
pmid:11405644
|
Setlow JK et al. |
Evidence for gene silencing in Haemophilus influenzae. |
2001 |
Mutat. Res. |
pmid:11406170
|
Singal R et al. |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. |
2001 |
Cancer Res. |
pmid:11406558
|
Baur JA et al. |
Telomere position effect in human cells. |
2001 |
Science |
pmid:11408657
|
Zelivianski S et al. |
Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype. |
2001 |
Biochim. Biophys. Acta |
pmid:11389966
|
Feng YQ et al. |
Position effects are influenced by the orientation of a transgene with respect to flanking chromatin. |
2001 |
Mol. Cell. Biol. |
pmid:11113204
|
Harada Y et al. |
A hematopoietic-specific transmembrane protein, Art-1, is possibly regulated by AML1. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11396961
|
Mehra-Chaudhary R et al. |
Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. |
2001 |
Biochem. J. |
pmid:11115394
|
Osborne A et al. |
Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
2001 |
Mol. Cell. Biol. |
pmid:11533238
|
Yang H et al. |
Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:11208539
|
Chen C et al. |
Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites. |
2001 |
J. Biol. Chem. |
pmid:11013250
|
Ullerås E et al. |
Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer. |
2001 |
Exp. Cell Res. |
pmid:11640883
|
Arthur JL et al. |
Herpes simplex virus type 1 promoter activity during latency establishment, maintenance, and reactivation in primary dorsal root neurons in vitro. |
2001 |
J. Virol. |
pmid:11264377
|
Wu JT et al. |
Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:11171632
|
Taddei A et al. |
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. |
2001 |
Nat. Cell Biol. |
pmid:11175742
|
Ferrara FF et al. |
Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. |
2001 |
Cancer Res. |
pmid:11196162
|
Furumai R et al. |
Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11134513
|
Johnson CA et al. |
Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
2001 |
J. Biol. Chem. |
pmid:11136718
|
Griswold MD et al. |
Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11223181
|
Chang YC et al. |
Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. |
2001 |
Mol. Cell. Biol. |
pmid:11158299
|
Newell-Price J et al. |
The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression. |
2001 |
Mol. Endocrinol. |
pmid:11158338
|
Kamitani H et al. |
Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma. |
2001 |
Carcinogenesis |
pmid:11159758
|
Shestakova E et al. |
Inhibition of histone deacetylation induces constitutive derepression of the beta interferon promoter and confers antiviral activity. |
2001 |
J. Virol. |
pmid:11238870
|
Kuwahara K et al. |
The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11238943
|
Meier JL |
Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator. |
2001 |
J. Virol. |
pmid:11160656
|
Kuusisto E et al. |
Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11162503
|
Grandjean V et al. |
Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. |
2001 |
FEBS Lett. |
pmid:11163765
|
Lizcano F et al. |
Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11165035
|
Nervi C et al. |
Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity. |
2001 |
Cancer Res. |
pmid:11245412
|
Zhu WG et al. |
DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. |
2001 |
Cancer Res. |
pmid:11245429
|
Muth V et al. |
Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. |
2001 |
EMBO J. |
pmid:11250901
|
Laribee RN and Klemsz MJ |
Loss of PU.1 expression following inhibition of histone deacetylases. |
2001 |
J. Immunol. |
pmid:11673528
|
He LZ et al. |
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. |
2001 |
J. Clin. Invest. |
pmid:11696577
|