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Neuron restrictive silencer factor NRSF/REST is a transcriptional repressor of neuropilin-1 and diminishes the ability of semaphorin 3A to inhibit keratinocyte migration. |
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Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis? |
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A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells. |
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A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. |
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The major histocompatibility complex class II transactivator is differentially regulated by interferon-gamma and transforming growth factor-beta in microglial cells. |
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2006 |
Hum. Cell |
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2006 |
Cell Cycle |
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2006 |
Cell Cycle |
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2006 |
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Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. |
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Mol. Cell |
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Cell Res. |
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Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS. |
2006 |
Am. J. Physiol. Endocrinol. Metab. |
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Inhibition of proliferation of endometrial stromal cells by trichostatin A, RU486, CDB-2914, N-acetylcysteine, and ICI 182780. |
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Folia Biol. (Praha) |
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Neuroscience |
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Phosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of transcription of the luteinizing hormone receptor gene. |
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Targeted histone H4 acetylation via phosphoinositide 3-kinase- and p70s6-kinase-dependent pathways inhibits iNOS induction in mesangial cells. |
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Am. J. Physiol. Renal Physiol. |
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Oncogene |
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Histone deacetylase 3 represses HTLV-1 tax transcription. |
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Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction. |
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Mol. Cancer |
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Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells. |
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Mol. Cancer |
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Nat Protoc |
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Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells. |
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Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. |
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Biochim. Biophys. Acta |
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Bsr, a nuclear-retained RNA with monoallelic expression. |
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Mol. Biol. Cell |
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Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver. |
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Surgery |
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ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. |
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Biochem. Biophys. Res. Commun. |
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Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. |
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Mol. Cell. Biol. |
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The combination of the histone-deacetylase inhibitor trichostatin A and gemcitabine induces inhibition of proliferation and increased apoptosis in pancreatic carcinoma cells. |
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Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica. |
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BMC Genomics |
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Haploinsufficient prostate tumor suppression by Nkx3.1: a role for chromatin accessibility in dosage-sensitive gene regulation. |
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Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis. |
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Arthritis Rheum. |
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Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. |
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Blood |
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Differential regulation of thrombospondin-1 expression and antiangiogenesis of ECV304 cells by trichostatin A and helixor A. |
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Anticancer Drugs |
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Activation of elastin transcription by transforming growth factor-beta in human lung fibroblasts. |
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Am. J. Physiol. Lung Cell Mol. Physiol. |
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Expression of GAGE family proteins in malignant melanoma. |
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Cancer Lett. |
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Inhibition of histone deacetylation promotes abnormal epidermal differentiation and specifically suppresses the expression of the late differentiation marker profilaggrin. |
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J. Invest. Dermatol. |
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HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region. |
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Effect of histone deacetylase inhibitor trichostatin A (TSA) on the microtubular system of Tetrahymena. |
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[Role of human telomerase reverse transcriptase in apoptosis of human umbilical vein endothelial cells induced by trichostatin A]. |
2007 |
Zhonghua Zhong Liu Za Zhi |
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Regulation of neuronal nitric oxide synthase exon 1f gene expression by nuclear factor-kappaB acetylation in human neuroblastoma cells. |
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J. Neurochem. |
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Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor. |
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Bioorg. Med. Chem. Lett. |
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Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression. |
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Exp. Hematol. |
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Enhancing the anti-angiogenic action of histone deacetylase inhibitors. |
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Mol. Cancer |
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Epigenetic alteration of the donor cells does not recapitulate the reprogramming of DNA methylation in cloned embryos. |
2007 |
Reproduction |
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