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Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells. |
2008 |
Cancer Immunol. Immunother. |
pmid:18046553
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Li X et al. |
The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts. |
2008 |
Cloning Stem Cells |
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Pandey SC et al. |
Brain chromatin remodeling: a novel mechanism of alcoholism. |
2008 |
J. Neurosci. |
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Fontán-Lozano A et al. |
Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice. |
2008 |
Mol. Cell. Neurosci. |
pmid:18638560
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Kovács P and Csaba G |
The effect of histone deacetylase inhibitor trichostatin A (TSA) on the incorporation of 32P (Pi) and 3H-palmitic acid into the phospholipids of Tetrahymena. |
2008 Jan-Feb |
Cell Biochem. Funct. |
pmid:17191269
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Smetana K et al. |
To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A. |
2008 Jul-Sep |
Eur J Histochem |
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Fenic I et al. |
In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. |
2008 Mar-Apr |
J. Androl. |
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Nishikiori N et al. |
Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. |
2008 May-Jun |
Jpn. J. Ophthalmol. |
pmid:18661270
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Li X and Bai XZ |
[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
pmid:19140318
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Kir'ianov GI et al. |
[Nucleosome positioning within neomycinphosphotransferase gene (NPTII) on yeast plasmid in repressed and active state]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
pmid:19140324
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Miyoshi M et al. |
Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells. |
2008 Nov-Dec |
Nutrition |
pmid:18723323
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Susick L et al. |
Regulatory roles for histone deacetylation in IL-1beta-induced nitric oxide release in pancreatic beta-cells. |
2008 Sep-Oct |
J. Cell. Mol. Med. |
pmid:18053091
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Cecconi D et al. |
Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. |
2009 |
Proteomics |
pmid:19294695
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Ikeda S et al. |
Enhancement of histone acetylation by trichostatin A during in vitro fertilization of bovine oocytes affects cell number of the inner cell mass of the resulting blastocysts. |
2009 |
Zygote |
pmid:19356267
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Morita K et al. |
Histone deacetylase inhibitors promote neurosteroid-mediated cell differentiation and enhance serotonin-stimulated brain-derived neurotrophic factor gene expression in rat C6 glioma cells. |
2009 |
J. Neurosci. Res. |
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von Burstin J et al. |
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. |
2009 |
Gastroenterology |
pmid:19362090
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Yang X et al. |
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. |
2009 |
PLoS ONE |
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Slattery EL et al. |
Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle. |
2009 |
J. Assoc. Res. Otolaryngol. |
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Vilar E et al. |
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. |
2009 |
Clin. Cancer Res. |
pmid:19351759
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Lu SC et al. |
The essential role of Oct-2 in LPS-induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19279235
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Luo SF et al. |
Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. |
2009 |
Toxicol. Appl. Pharmacol. |
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Giannini G et al. |
N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
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Ueda JY et al. |
JBIR-17, a novel trichostatin analog from Streptomyces sp. 26634. |
2009 |
J. Antibiot. |
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Noro R et al. |
The anticancer effect of histone deacetylase inhibitors and combination with the cytotoxic agents in lung cancer cells: biological analyses for future clinical application. |
2009 |
J Nippon Med Sch |
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Meng CF et al. |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. |
2009 |
Zhonghua Wei Chang Wai Ke Za Zhi |
pmid:19742343
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Dombrowsky H et al. |
Conserved responses to trichostatin A in rodent lungs exposed to endotoxin or stretch. |
2009 |
Pulm Pharmacol Ther |
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Dandrea M et al. |
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. |
2009 |
Nucleic Acids Res. |
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Lugrin J et al. |
Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation. |
2009 |
Biochim. Biophys. Acta |
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Cervera RP et al. |
Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryos. |
2009 |
Theriogenology |
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Diplas AI et al. |
Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. |
2009 |
Nucleic Acids Res. |
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Ma XX et al. |
Histone deacetylase inhibitor trichostatin A modulates cell cycles in A2780 human ovarian cancer cell lines. |
2009 |
Eur. J. Gynaecol. Oncol. |
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Izawa M et al. |
Inhibition of histone deacetylase causes reduction of appressorium formation in the rice blast fungus Magnaporthe oryzae. |
2009 |
J. Gen. Appl. Microbiol. |
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Guo W et al. |
Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition. |
2009 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Yamanaka K et al. |
Acetylation level of histone H3 in early embryonic stages affects subsequent development of miniature pig somatic cell nuclear transfer embryos. |
2009 |
J. Reprod. Dev. |
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McCulloch MW et al. |
Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives. |
2009 |
Bioorg. Med. Chem. |
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Chen FQ et al. |
Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. |
2009 |
J. Neurochem. |
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Zhao W et al. |
Histone deacetylase inhibitor, trichostatin A, affects gene expression patterns during morphogenesis of chicken limb buds in vivo. |
2009 |
Cells Tissues Organs (Print) |
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Giustiniani J et al. |
Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53. |
2009 |
Cell. Signal. |
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Chen Y et al. |
3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment. |
2009 |
Eur J Med Chem |
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Cowell RM et al. |
Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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Wiesen JL and Tomasi TB |
Dicer is regulated by cellular stresses and interferons. |
2009 |
Mol. Immunol. |
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Togi S et al. |
HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A. |
2009 |
Biochem. Biophys. Res. Commun. |
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Dje N'Guessan P et al. |
Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
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Yamada N et al. |
Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. |
2009 |
Br. J. Cancer |
pmid:19127263
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Mavis CK et al. |
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. |
2009 |
Prostate |
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Samuni Y et al. |
The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation. |
2009 |
Free Radic. Biol. Med. |
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Gavin DP et al. |
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. |
2009 |
J Psychiatry Neurosci |
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Astrand C et al. |
Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter. |
2009 |
Exp. Cell Res. |
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Riester D et al. |
Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. |
2009 |
Bioorg. Med. Chem. Lett. |
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Kim HN et al. |
Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. |
2009 |
Eur. J. Pharmacol. |
pmid:19766111
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Woodfield GW et al. |
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. |
2009 |
Clin. Cancer Res. |
pmid:19458056
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Hauswald S et al. |
Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes. |
2009 |
Clin. Cancer Res. |
pmid:19458058
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Arce L et al. |
Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression. |
2009 |
BMC Cancer |
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Petr J et al. |
Histone deacetylase inhibition improves meiotic competence but not developmental competence in growing pig oocytes. |
2009 |
Zygote |
pmid:19460191
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Ku WC et al. |
Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. |
2009 |
Mol. Cell Proteomics |
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Kondo T et al. |
Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas. |
2009 |
Lab. Invest. |
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Bonetto A et al. |
Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. |
2009 |
Curr Cancer Drug Targets |
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Dubois F et al. |
Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni. |
2009 |
Mol. Biochem. Parasitol. |
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Ma XL et al. |
[Construction of anti-sense cDNA library of human breast cancer cells during apoptosis induced by trichostatin A and preliminary screening of essential genes]. |
2009 |
Zhonghua Yi Xue Za Zhi |
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Use of epigenetic modification to induce FOXP3 expression in naïve T cells. |
2009 |
Transplant. Proc. |
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Thiel A et al. |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. |
2009 |
Clin. Cancer Res. |
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Rahim R and Strobl JS |
Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells. |
2009 |
Anticancer Drugs |
pmid:19584707
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Nadasi E et al. |
Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. |
2009 |
Anticancer Res. |
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Giustiniani J et al. |
Basal endothelial nitric oxide synthase (eNOS) phosphorylation on Ser(1177) occurs in a stable microtubule- and tubulin acetylation-dependent manner. |
2009 |
Exp. Cell Res. |
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Chandrasekaran S et al. |
Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes. |
2009 |
FASEB J. |
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Imesch P et al. |
MLH1 protects from resistance acquisition by the histone deacetylase inhibitor trichostatin A in colon tumor cells. |
2009 |
Int. J. Oncol. |
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Liu X et al. |
The improvement of adenovirus vector production by increased expression of coxsackie adenovirus receptor. |
2009 |
Biotechnol. Lett. |
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Hollosi P et al. |
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. |
2009 |
Int. J. Cancer |
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Chen J et al. |
E1A has no effect on LPS-induced IL-6 secretion in rat alveolar epithelial cells. |
2009 |
Respiration |
pmid:19299891
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Shao GB et al. |
Effect of trychostatin A treatment on gene expression in cloned mouse embryos. |
2009 |
Theriogenology |
pmid:19246084
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Cunneen TS et al. |
In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. |
2009 |
Arch. Ophthalmol. |
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Charrier C et al. |
Synthesis and modeling of new benzofuranone histone deacetylase inhibitors that stimulate tumor suppressor gene expression. |
2009 |
J. Med. Chem. |
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Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. |
2009 |
Anticancer Res. |
pmid:19331143
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Åuczak MW and JagodziÅ„ski PP |
Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
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Puca R et al. |
HIPK2 modulates p53 activity towards pro-apoptotic transcription. |
2009 |
Mol. Cancer |
pmid:19828042
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Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. |
2009 |
Mol. Cancer |
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Wang Y et al. |
HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. |
2009 |
Neurosci. Lett. |
pmid:19835929
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Mastitskaya S and Denecke B |
Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro. |
2009 |
J Negat Results Biomed |
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Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. |
2009 |
Mol. Cancer Ther. |
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Koh HS et al. |
Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells. |
2009 |
Mol. Cells |
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Federman N et al. |
Histone acetylation is recruited in consolidation as a molecular feature of stronger memories. |
2009 |
Learn. Mem. |
pmid:19794185
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Auer D et al. |
Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
pmid:18618240
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Sharma A et al. |
Trichostatin a inhibits corneal haze in vitro and in vivo. |
2009 |
Invest. Ophthalmol. Vis. Sci. |
pmid:19168895
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Zubia A et al. |
Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity. |
2009 |
Oncogene |
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Meng Q et al. |
Live birth of somatic cell-cloned rabbits following trichostatin A treatment and cotransfer of parthenogenetic embryos. |
2009 |
Cloning Stem Cells |
pmid:19196041
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Gray SG et al. |
Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications. |
2009 |
Eur. J. Cancer |
pmid:19818596
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Zhang F et al. |
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. |
2009 |
Cancer Biol. Ther. |
pmid:19270532
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Hara D et al. |
Persistent BDNF exon I-IX mRNA expression following the withdrawal of neuronal activity in neurons. |
2009 |
Biochem. Biophys. Res. Commun. |
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Tan HH and Porter AG |
p21(WAF1) negatively regulates DNMT1 expression in mammalian cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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Li C et al. |
Induction of myelogenous leukemia cells with histone deacetylase inhibitors through down-regulating the Daxx protein expression. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
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Gavin DP et al. |
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population. |
2009 |
J Psychiatr Res |
pmid:19187942
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Liberatore RA et al. |
NF-kappaB activity is constitutively elevated in c-Abl null fibroblasts. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805123
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Sasaki K et al. |
Real-time imaging of histone H4 hyperacetylation in living cells. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805290
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Gibbs A et al. |
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805354
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Popova EY et al. |
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. |
2009 |
Chromosome Res. |
pmid:19172406
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Tsuji Y et al. |
The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine. |
2009 |
Zygote |
pmid:19175955
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Lee JH et al. |
Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. |
2009 |
Mol. Cancer Res. |
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Bao Y et al. |
Identification of trichostatin A as a novel transcriptional up-regulator of scavenger receptor BI both in HepG2 and RAW 264.7 cells. |
2009 |
Atherosclerosis |
pmid:18930459
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Chen CZ et al. |
The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well. |
2009 |
Br. J. Pharmacol. |
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Hoebeeck J et al. |
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. |
2009 |
Cancer Lett. |
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