Saleh M et al. |
Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases. |
2000 |
Mol. Cell. Biol. |
pmid:11046157
|
Chang LK and Liu ST |
Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation. |
2000 |
Nucleic Acids Res. |
pmid:11024171
|
Suzuki T et al. |
Effect of trichostatin A on cell growth and expression of cell cycle- and apoptosis-related molecules in human gastric and oral carcinoma cell lines. |
2000 |
Int. J. Cancer |
pmid:11093826
|
Sutcliffe JE et al. |
Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription. |
2000 |
Mol. Cell. Biol. |
pmid:11094071
|
Magner WJ et al. |
Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors. |
2000 |
J. Immunol. |
pmid:11120829
|
Damjanovski S et al. |
Multiple stage-dependent roles for histone deacetylases during amphibian embryogenesis: implications for the involvement of extracellular matrix remodeling. |
2000 |
Int. J. Dev. Biol. |
pmid:11128570
|
Liang L et al. |
Dynamic readjustment of parental methylation patterns of the 5'-flank of the mouse H19 gene during in vitro organogenesis. |
2000 |
Int. J. Dev. Biol. |
pmid:11128572
|
Gaetano C et al. |
Transcriptionally active drugs improve adenovirus vector performance in vitro and in vivo. |
2000 |
Gene Ther. |
pmid:11083470
|
Maecker HL et al. |
p53 promotes selection for Fas-mediated apoptotic resistance. |
2000 |
Cancer Res. |
pmid:10969818
|
Asoh S et al. |
The super anti-apoptotic factor Bcl-xFNK constructed by disturbing intramolecular polar interactions in rat Bcl-xL. |
2000 |
J. Biol. Chem. |
pmid:10970895
|
Cong YS and Bacchetti S |
Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells. |
2000 |
J. Biol. Chem. |
pmid:10986277
|
Wei LN et al. |
Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing. |
2000 |
J. Biol. Chem. |
pmid:11006275
|
Stöckel B et al. |
Characterization of the 5'-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison withthe multidrug resistance protein 3 (MRP3) gene. |
2000 |
Eur. J. Biochem. |
pmid:10691972
|
Imai S et al. |
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. |
2000 |
Nature |
pmid:10693811
|
Sirchia SM et al. |
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells. |
2000 |
Oncogene |
pmid:10734315
|
Hodny Z et al. |
Sp1 and chromatin environment are important contributors to the formation of repressive chromatin structures on the transfected human adenine nucleotide translocase-2 promoter. |
2000 |
Biochem. J. |
pmid:10657244
|
Garrison PM et al. |
Effects of histone deacetylase inhibitors on the Ah receptor gene promoter. |
2000 |
Arch. Biochem. Biophys. |
pmid:10666294
|
Smith RD et al. |
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. |
2000 |
Blood |
pmid:10648397
|
Nakayama T et al. |
Epigenetic regulation of androgen receptor gene expression in human prostate cancers. |
2000 |
Lab. Invest. |
pmid:11140692
|
Dressel U et al. |
Promoter specific sensitivity to inhibition of histone deacetylases: implications for hormonal gene control, cellular differentiation and cancer. |
2000 Mar-Apr |
Anticancer Res. |
pmid:10810390
|
Steinbac OC et al. |
Histone deacetylase activity is required for the induction of the MyoD muscle cell lineage in Xenopus. |
2000 Sep-Oct |
Biol. Chem. |
pmid:11076034
|
Amin HM et al. |
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). |
2001 |
Br. J. Haematol. |
pmid:11703323
|
Pile LA et al. |
The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
2001 |
Cell. Mol. Life Sci. |
pmid:11706997
|
Sachs LM et al. |
An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. |
2001 |
Int. J. Mol. Med. |
pmid:11712071
|
Lefevre P et al. |
Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
2001 |
Nucleic Acids Res. |
pmid:11713304
|
Sekita N et al. |
Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. |
2001 |
Jpn. J. Cancer Res. |
pmid:11572762
|
Yin L et al. |
Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. |
2001 |
J. Biol. Chem. |
pmid:11572859
|
Leng SL et al. |
Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. |
2001 |
Carcinogenesis |
pmid:11577001
|
Yang X et al. |
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. |
2001 |
Cancer Res. |
pmid:11585728
|
Abderrahmani A et al. |
The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). |
2001 |
Mol. Cell. Biol. |
pmid:11585908
|
Yoshida M et al. |
Histone deacetylase as a new target for cancer chemotherapy. |
2001 |
Cancer Chemother. Pharmacol. |
pmid:11587361
|
Jung M |
Inhibitors of histone deacetylase as new anticancer agents. |
2001 |
Curr. Med. Chem. |
pmid:11562279
|
Ashburner BP et al. |
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. |
2001 |
Mol. Cell. Biol. |
pmid:11564889
|
Sachs LM et al. |
Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis. |
2001 |
Dev. Dyn. |
pmid:11668605
|
Amann JM et al. |
ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. |
2001 |
Mol. Cell. Biol. |
pmid:11533236
|
Sutherland JE et al. |
The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells. |
2001 |
Mutat. Res. |
pmid:11470494
|
Takakura M et al. |
Telomerase activation by histone deacetylase inhibitor in normal cells. |
2001 |
Nucleic Acids Res. |
pmid:11452025
|
Ferraro M et al. |
Involvement of histone H4 acetylation in the epigenetic inheritance of different activity states of maternally and paternally derived genomes in the mealybug Planococcus citri. |
2001 |
Chromosoma |
pmid:11453559
|
Marianna P et al. |
Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. |
2001 |
Haematologica |
pmid:11454524
|
Cho JH et al. |
DNA methylation regulates placental lactogen I gene expression. |
2001 |
Endocrinology |
pmid:11459782
|
Walker GE et al. |
Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
pmid:11517158
|
Jorgensen JS and Nilson JH |
AR suppresses transcription of the alpha glycoprotein hormone subunit gene through protein-protein interactions with cJun and activation transcription factor 2. |
2001 |
Mol. Endocrinol. |
pmid:11518798
|
Phiel CJ et al. |
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
2001 |
J. Biol. Chem. |
pmid:11473107
|
Sundqvist A et al. |
Functional knockout of the corepressor CtBP by the second exon of adenovirus E1a relieves repression of transcription. |
2001 |
Exp. Cell Res. |
pmid:11478854
|
Jacob AL et al. |
Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. |
2001 |
J. Biol. Chem. |
pmid:11479297
|
Sourlingas TG et al. |
Histone deacetylase inhibitors induce apoptosis in peripheral blood lymphocytes along with histone H4 acetylation and the expression of the linker histone variant, H1 degrees. |
2001 |
Eur. J. Cell Biol. |
pmid:11824792
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. |
2001 |
Brain Tumor Pathol |
pmid:11908866
|
Lavelle D et al. |
Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. |
2001 |
Am. J. Hematol. |
pmid:11754398
|
Williams RJ |
Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis. |
2001 |
Expert Opin Investig Drugs |
pmid:11785457
|
Benjamin D and Jost JP |
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
pmid:11522830
|
Li J et al. |
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
2001 |
Mol. Cell. Biol. |
pmid:11689710
|
Hirschler-Laszkiewicz I et al. |
The role of acetylation in rDNA transcription. |
2001 |
Nucleic Acids Res. |
pmid:11600700
|
Nair AR et al. |
Paradoxical effects of trichostatin A: inhibition of NF-Y-associated histone acetyltransferase activity, phosphorylation of hGCN5 and downregulation of cyclin A and B1 mRNA. |
2001 |
Cancer Lett. |
pmid:11295287
|
Hatama S et al. |
Reactivation of feline foamy virus from a chronically infected feline renal cell line by trichostatin A. |
2001 |
Virology |
pmid:11336556
|
Viollet B et al. |
Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1alpha (HNF1alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1alpha-deficient hepatocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11340160
|
Nakamura M et al. |
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor. |
2001 |
J. Cell. Physiol. |
pmid:11319763
|
Xu D et al. |
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11274400
|
Seth KA and Majzoub JA |
Repressor element silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) can act as an enhancer as well as a repressor of corticotropin-releasing hormone gene transcription. |
2001 |
J. Biol. Chem. |
pmid:11278361
|
Matsuda E et al. |
Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms. |
2001 |
J. Biol. Chem. |
pmid:11278721
|
Rashid SF et al. |
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
2001 |
Oncogene |
pmid:11313934
|
Segev H et al. |
Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development. |
2001 |
Zygote |
pmid:11358320
|
Archer SY et al. |
p21 gene regulation during enterocyte differentiation. |
2001 |
J. Surg. Res. |
pmid:11368530
|
Ma J et al. |
Regulation of zygotic gene activation in the preimplantation mouse embryo: global activation and repression of gene expression. |
2001 |
Biol. Reprod. |
pmid:11369600
|
Della Ragione F et al. |
Genes modulated by histone acetylation as new effectors of butyrate activity. |
2001 |
FEBS Lett. |
pmid:11423116
|
Maës J et al. |
Chromatin remodeling at the Ig loci prior to V(D)J recombination. |
2001 |
J. Immunol. |
pmid:11441093
|
Wang H et al. |
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
2001 |
Science |
pmid:11387442
|
Klar AJ et al. |
A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
pmid:11404352
|
Massa S et al. |
3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. |
2001 |
J. Med. Chem. |
pmid:11405644
|
Setlow JK et al. |
Evidence for gene silencing in Haemophilus influenzae. |
2001 |
Mutat. Res. |
pmid:11406170
|
Singal R et al. |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. |
2001 |
Cancer Res. |
pmid:11406558
|
Baur JA et al. |
Telomere position effect in human cells. |
2001 |
Science |
pmid:11408657
|
Zelivianski S et al. |
Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype. |
2001 |
Biochim. Biophys. Acta |
pmid:11389966
|
Feng YQ et al. |
Position effects are influenced by the orientation of a transgene with respect to flanking chromatin. |
2001 |
Mol. Cell. Biol. |
pmid:11113204
|
Harada Y et al. |
A hematopoietic-specific transmembrane protein, Art-1, is possibly regulated by AML1. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11396961
|
Osborne A et al. |
Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
2001 |
Mol. Cell. Biol. |
pmid:11533238
|
Yang H et al. |
Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:11208539
|
Chen C et al. |
Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites. |
2001 |
J. Biol. Chem. |
pmid:11013250
|
Ullerås E et al. |
Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer. |
2001 |
Exp. Cell Res. |
pmid:11640883
|
Kosugi H et al. |
In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice. |
2001 |
Jpn. J. Cancer Res. |
pmid:11376562
|
Arthur JL et al. |
Herpes simplex virus type 1 promoter activity during latency establishment, maintenance, and reactivation in primary dorsal root neurons in vitro. |
2001 |
J. Virol. |
pmid:11264377
|
Wu JT et al. |
Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:11171632
|
Taddei A et al. |
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. |
2001 |
Nat. Cell Biol. |
pmid:11175742
|
Ferrara FF et al. |
Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. |
2001 |
Cancer Res. |
pmid:11196162
|
Furumai R et al. |
Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11134513
|
Johnson CA et al. |
Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
2001 |
J. Biol. Chem. |
pmid:11136718
|
Griswold MD et al. |
Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11223181
|
Chang YC et al. |
Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. |
2001 |
Mol. Cell. Biol. |
pmid:11158299
|
Newell-Price J et al. |
The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression. |
2001 |
Mol. Endocrinol. |
pmid:11158338
|
Kamitani H et al. |
Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma. |
2001 |
Carcinogenesis |
pmid:11159758
|
Shestakova E et al. |
Inhibition of histone deacetylation induces constitutive derepression of the beta interferon promoter and confers antiviral activity. |
2001 |
J. Virol. |
pmid:11238870
|
Kuwahara K et al. |
The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11238943
|
Meier JL |
Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator. |
2001 |
J. Virol. |
pmid:11160656
|
Kuusisto E et al. |
Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11162503
|
Grandjean V et al. |
Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. |
2001 |
FEBS Lett. |
pmid:11163765
|
Lizcano F et al. |
Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11165035
|
Lavoie R et al. |
Design and synthesis of a novel class of histone deacetylase inhibitors. |
2001 |
Bioorg. Med. Chem. Lett. |
pmid:11597413
|
Bernhard D et al. |
Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. |
2001 |
Cell Death Differ. |
pmid:11598799
|
Hatama S et al. |
Isolation and sequencing of infectious clones of feline foamy virus and a human/feline foamy virus Env chimera. |
2001 |
J. Gen. Virol. |
pmid:11714976
|
Yoshioka H et al. |
A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting. |
2001 |
J. Hum. Genet. |
pmid:11721881
|
He LZ et al. |
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. |
2001 |
J. Clin. Invest. |
pmid:11696577
|