Cheutin T et al. |
Maintenance of stable heterochromatin domains by dynamic HP1 binding. |
2003 |
Science |
pmid:12560555
|
Boutillier AL et al. |
Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis. |
2003 |
J. Neurochem. |
pmid:12562525
|
Tomita K et al. |
The effect of oxidative stress on histone acetylation and IL-8 release. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12565901
|
Kim Y et al. |
Decreased syndecan-2 expression correlates with trichostatin-A induced-morphological changes and reduced tumorigenic activity in colon carcinoma cells. |
2003 |
Oncogene |
pmid:12584561
|
Ding Z et al. |
Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain. |
2003 |
Mol. Cell. Biol. |
pmid:12482978
|
Obata T et al. |
Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer. |
2003 |
Clin. Cancer Res. |
pmid:14695142
|
Terui T et al. |
Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors. |
2003 |
Cancer Res. |
pmid:14695212
|
Pivot-Pajot C et al. |
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. |
2003 |
Mol. Cell. Biol. |
pmid:12861021
|
Grassi G et al. |
Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87. |
2003 |
Carcinogenesis |
pmid:12869421
|
Ammanamanchi S et al. |
Acetylated sp3 is a transcriptional activator. |
2003 |
J. Biol. Chem. |
pmid:12837748
|
Krämer OH et al. |
The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. |
2003 |
EMBO J. |
pmid:12840003
|
Kishikawa S et al. |
Control elements of Dnmt1 gene are regulated in cell-cycle dependent manner. |
2003 |
Nucleic Acids Res. Suppl. |
pmid:14510503
|
Wegener D et al. |
Improved fluorogenic histone deacetylase assay for high-throughput-screening applications. |
2003 |
Anal. Biochem. |
pmid:14511685
|
Kim MS et al. |
Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. |
2003 |
Cancer Res. |
pmid:14612526
|
Park KK et al. |
Modulation of Sp1-dependent transcription by a cis-acting E2F element in dhfr promoter. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12788094
|
Marks J et al. |
Two functionally divergent p53-responsive elements in the rat bradykinin B2 receptor promoter. |
2003 |
J. Biol. Chem. |
pmid:12791684
|
Valls E et al. |
The SV40 T antigen modulates CBP histone acetyltransferase activity. |
2003 |
Nucleic Acids Res. |
pmid:12799439
|
Ferguson M et al. |
Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene. |
2003 |
Nucleic Acids Res. |
pmid:12799440
|
Ji Y et al. |
A multistep mechanism for the activation of rearrangement in the immune system. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12802019
|
Enright BP et al. |
Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine. |
2003 |
Biol. Reprod. |
pmid:12748129
|
Van Ommeslaeghe K et al. |
Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12749885
|
Zhao S et al. |
Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells. |
2003 |
Cancer Res. |
pmid:12750289
|
Schauber J et al. |
Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. |
2003 |
Gut |
pmid:12692061
|
Rambhatla L et al. |
Generation of hepatocyte-like cells from human embryonic stem cells. |
2003 |
Cell Transplant |
pmid:12693659
|
Kao HH et al. |
Genomic structure, gene expression, and promoter analysis of human multidrug resistance-associated protein 7. |
2003 Jan-Feb |
J. Biomed. Sci. |
pmid:12566991
|
Kagoshima M et al. |
How signaling pathways interact with gene transcription. |
2003 Jan-Mar |
Monaldi Arch Chest Dis |
pmid:14533280
|
Swank RA et al. |
The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced gamma globin expression in somatic cell hybrids and induces gamma gene expression in adult BFUe cultures. |
2003 May-Jun |
Blood Cells Mol. Dis. |
pmid:12737942
|
Flørenes VA et al. |
Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival. |
2004 |
Melanoma Res. |
pmid:15179185
|
Ahn MR et al. |
Trichostatin A, a histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in Hepa-I cells. |
2004 |
Arch. Pharm. Res. |
pmid:15180307
|
Vanhaecke T et al. |
Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view. |
2004 |
Curr. Med. Chem. |
pmid:15180568
|
Kato N et al. |
Regulation of Chk2 gene expression in lymphoid malignancies: involvement of epigenetic mechanisms in Hodgkin's lymphoma cell lines. |
2004 |
Cell Death Differ. |
pmid:15153943
|
Ramakrishnan G et al. |
Histone acetyltransferases and deacetylase in Entamoeba histolytica. |
2004 |
Mol. Biochem. Parasitol. |
pmid:15555732
|
Bayart E et al. |
A major role for mitotic CDC2 kinase inactivation in the establishment of the mitotic DNA damage checkpoint. |
2004 |
Cancer Res. |
pmid:15604258
|
Fu M et al. |
The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity. |
2004 |
J. Biol. Chem. |
pmid:15123687
|
Phan D et al. |
Identification of Sp2 as a transcriptional repressor of carcinoembryonic antigen-related cell adhesion molecule 1 in tumorigenesis. |
2004 |
Cancer Res. |
pmid:15126343
|
Iezzi S et al. |
Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. |
2004 |
Dev. Cell |
pmid:15130492
|
Bort R et al. |
Role of hepatocyte nuclear factor 3 gamma in the expression of human CYP2C genes. |
2004 |
Arch. Biochem. Biophys. |
pmid:15130783
|
Ishii S et al. |
Aberrant dynamics of histone deacetylation at the thyrotropin-releasing hormone gene in resistance to thyroid hormone. |
2004 |
Mol. Endocrinol. |
pmid:15131262
|
Winn RA and Heasley LE |
Gamma-catenin expression is reduced or absent in a subset of human non-small cell lung cancers, and its re-expression inhibits cell growth. |
2004 |
Chest |
pmid:15136458
|
Jin YH et al. |
Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation. |
2004 |
J. Biol. Chem. |
pmid:15138260
|
Milutinovic S et al. |
DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation. |
2004 |
J. Biol. Chem. |
pmid:15087453
|
Chang HC et al. |
Involvement of histone deacetylation in ras-induced down-regulation of the metastasis suppressor RECK. |
2004 |
Cell. Signal. |
pmid:15093608
|
Nishino N et al. |
Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15109626
|
Marson CM et al. |
Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2E,4E)-5-arylpenta-2,4-dienoic acid hydroxyamides. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15109636
|
Arapshian A et al. |
Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer. |
2004 |
Mol. Cancer |
pmid:15113415
|
Mizukami T et al. |
Effects of trichostatin a, a histone deacetylase inhibitor, on mouse gonadal development in vitro. |
2004 |
J. Reprod. Dev. |
pmid:15118250
|
Ganslmayer M et al. |
A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells. |
2004 |
Oncol. Rep. |
pmid:15069530
|
Lu XC et al. |
[Effect of inhibitors for demethylation and histone deacetylase on proliferation of cell line K562 and expression of tumor related genes]. |
2004 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:14989767
|
Nojima H et al. |
Increase in DNA methylation downregulates conceptus interferon-tau gene expression. |
2004 |
Mol. Reprod. Dev. |
pmid:14991730
|
Koch A et al. |
Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages. |
2004 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12871851
|
Wang DF et al. |
QSAR studies of PC-3 cell line inhibition activity of TSA and SAHA-like hydroxamic acids. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:14741273
|
Yan C et al. |
A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NF-kappaB motif drives the transition from a repressed to an activated state of gene expression. |
2004 |
FASEB J. |
pmid:14715692
|
Zelko IN and Folz RJ |
Sp1 and Sp3 transcription factors mediate trichostatin A-induced and basal expression of extracellular superoxide dismutase. |
2004 |
Free Radic. Biol. Med. |
pmid:15451065
|
Chiba T et al. |
Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells. |
2004 |
Oncology |
pmid:15452378
|
Kypreou KP et al. |
Age-dependent response of lymphocytes in the induction of the linker histone variant, H1 degrees and histone H4 acetylation after treatment with the histone deacetylase inhibitor, trichostatin A. |
2004 |
Exp. Gerontol. |
pmid:15050280
|
Jose B et al. |
Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15454224
|
Uramoto H et al. |
p73 competes with co-activators and recruits histone deacetylase to NF-Y in the repression of PDGF beta-receptor. |
2004 |
J. Cell. Sci. |
pmid:15454570
|
De La Fuente R et al. |
Major chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes is dispensable for global transcriptional silencing but required for centromeric heterochromatin function. |
2004 |
Dev. Biol. |
pmid:15501230
|
Lin AC et al. |
The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors. |
2004 |
J. Biol. Chem. |
pmid:15507435
|
Wang S and Zhu J |
The hTERT gene is embedded in a nuclease-resistant chromatin domain. |
2004 |
J. Biol. Chem. |
pmid:15516693
|
El-Khoury V et al. |
Effects of the histone deacetylase inhibitor trichostatin A on nuclear texture and c-jun gene expression in drug-sensitive and drug-resistant human H69 lung carcinoma cells. |
2004 |
Cytometry A |
pmid:15517561
|
Vaquero A et al. |
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. |
2004 |
Mol. Cell |
pmid:15469825
|
Ladd PD et al. |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. |
2004 |
Gene |
pmid:15474314
|
Li H and Wu X |
Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474507
|
Spenger A et al. |
Influence of promoter choice and trichostatin A treatment on expression of baculovirus delivered genes in mammalian cells. |
2004 |
Protein Expr. Purif. |
pmid:15477077
|
Yee SB et al. |
Trichostatin A induces apoptosis of p815 mastocytoma cells in histone acetylation- and mitochondria-dependent fashion. |
2004 |
Int. J. Oncol. |
pmid:15492835
|
Young JC et al. |
Inhibitors of histone deacetylases promote hematopoietic stem cell self-renewal. |
2004 |
Cytotherapy |
pmid:16146885
|
Um SJ et al. |
In vitro antitumor potential of 4-BPRE, a butyryl aminophenyl ester of retinoic acid: role of the butyryl group. |
2004 |
Oncol. Rep. |
pmid:14767528
|
Astrand C et al. |
Trichostatin A reduces hormone-induced transcription of the MMTV promoter and has pleiotropic effects on its chromatin structure. |
2004 |
Eur. J. Biochem. |
pmid:15009194
|
Chen YX et al. |
Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines. |
2004 |
World J. Gastroenterol. |
pmid:15309711
|
Heltweg B et al. |
Subtype selective substrates for histone deacetylases. |
2004 |
J. Med. Chem. |
pmid:15456267
|
Alikhani-Koopaei R et al. |
Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. |
2004 |
J. Clin. Invest. |
pmid:15489962
|
Marsili G et al. |
Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15659847
|
Jang ER et al. |
The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen. |
2004 |
Oncogene |
pmid:14676837
|
Thelen P et al. |
Expressional changes after histone deacetylase inhibition by valproic acid in LNCaP human prostate cancer cells. |
2004 |
Int. J. Oncol. |
pmid:14654937
|
Kramps C et al. |
E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas. |
2004 |
J. Biol. Chem. |
pmid:14645238
|
Iijima K et al. |
Granulocytic differentiation of leukemic cells with t(9;11)(p22;q23) induced by all-trans-retinoic acid. |
2004 |
Leuk. Lymphoma |
pmid:15291362
|
Tóth KF et al. |
Trichostatin A-induced histone acetylation causes decondensation of interphase chromatin. |
2004 |
J. Cell. Sci. |
pmid:15292402
|
Myzak MC et al. |
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. |
2004 |
Cancer Res. |
pmid:15313918
|
Facchetti F et al. |
Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors. |
2004 |
Apoptosis |
pmid:15314285
|
Roh MS et al. |
Mechanism of histone deacetylase inhibitor Trichostatin A induced apoptosis in human osteosarcoma cells. |
2004 |
Apoptosis |
pmid:15314286
|
Yanaihara N et al. |
Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer. |
2004 |
Int. J. Cancer |
pmid:15305387
|
Munro J et al. |
Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock. |
2004 |
Exp. Cell Res. |
pmid:15093749
|
Gaudier E et al. |
Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:15308471
|
Schultz BE et al. |
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. |
2004 |
Biochemistry |
pmid:15323567
|
Tao D et al. |
Trichostatin A extends the lifespan of Drosophila melanogaster by elevating hsp22 expression. |
2004 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:15346199
|
Korkmaz CG et al. |
Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants. |
2004 |
J. Endocrinol. |
pmid:15350180
|
Akimoto T |
[Potentiation of radiation-induced cell killing by histone deacetylase inhibitor]. |
2004 |
Nippon Rinsho |
pmid:15283155
|
Joung KE et al. |
Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells. |
2004 |
Arch. Pharm. Res. |
pmid:15283467
|
Kang J et al. |
Synergistic killing of human leukemia cells by antioxidants and trichostatin A. |
2004 |
Cancer Chemother. Pharmacol. |
pmid:15248029
|
Chen WK et al. |
[Effect of trichostatin A on histone acetylation level and apoptosis in HL-60 cells]. |
2004 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:15228659
|
Kim JH et al. |
Susceptibility and radiosensitization of human glioblastoma cells to trichostatin A, a histone deacetylase inhibitor. |
2004 |
Int. J. Radiat. Oncol. Biol. Phys. |
pmid:15234053
|
Sakamoto S et al. |
Histone deacetylase activity is required to recruit RNA polymerase II to the promoters of selected interferon-stimulated early response genes. |
2004 |
J. Biol. Chem. |
pmid:15194680
|
Ng Y et al. |
Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. |
2004 |
J. Biol. Chem. |
pmid:15194684
|
Lu H et al. |
Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat. |
2004 |
J. Virol. |
pmid:15194748
|
Moldenhauer A et al. |
Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteins. |
2004 |
J. Leukoc. Biol. |
pmid:15197237
|
Min KN et al. |
Estrogen receptor enhances the antiproliferative effects of trichostatin A and HC-toxin in human breast cancer cells. |
2004 |
Arch. Pharm. Res. |
pmid:15202563
|
Jia S et al. |
RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins. |
2004 |
Science |
pmid:15218150
|
Sumer H et al. |
Effects of scaffold/matrix alteration on centromeric function and gene expression. |
2004 |
J. Biol. Chem. |
pmid:15220334
|
Lee YJ et al. |
Mechanism of transcriptional repression by TEL/RUNX1 fusion protein. |
2004 |
Mol. Cells |
pmid:15179033
|