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Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents. |
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Cancer Res. |
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2009 |
Clin. Cancer Res. |
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HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells. |
2009 |
J. Mol. Cell. Cardiol. |
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Caspase cleavage of Itch in chronic lymphocytic leukemia cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-kappaB. |
2009 |
Brain Res. Bull. |
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Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions. |
2009 |
Cell Cycle |
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Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. |
2009 |
Eur. J. Pharmacol. |
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Interspecies somatic cell nucleus transfer with porcine oocytes as recipients: A novel bioassay system for assessing the competence of canine somatic cells to develop into embryos. |
2009 |
Theriogenology |
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Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence. |
2009 |
J. Reprod. Immunol. |
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Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells. |
2009 |
Cell Prolif. |
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Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
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Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
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HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer. |
2009 |
Mol. Endocrinol. |
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Comparative epigenomics of human and mouse mammary tumors. |
2009 |
Genes Chromosomes Cancer |
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Regulatory roles for histone deacetylation in IL-1beta-induced nitric oxide release in pancreatic beta-cells. |
2008 Sep-Oct |
J. Cell. Mol. Med. |
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[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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[Nucleosome positioning within neomycinphosphotransferase gene (NPTII) on yeast plasmid in repressed and active state]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells. |
2008 Nov-Dec |
Nutrition |
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Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. |
2008 May-Jun |
Jpn. J. Ophthalmol. |
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In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. |
2008 Mar-Apr |
J. Androl. |
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To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A. |
2008 Jul-Sep |
Eur J Histochem |
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The effect of histone deacetylase inhibitor trichostatin A (TSA) on the incorporation of 32P (Pi) and 3H-palmitic acid into the phospholipids of Tetrahymena. |
2008 Jan-Feb |
Cell Biochem. Funct. |
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Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells. |
2008 |
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Effects of trichostatin A on neuronal mu-opioid receptor gene expression. |
2008 |
Brain Res. |
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Regulation of arginase-1 expression in macrophages by a protein kinase A type I and histone deacetylase dependent pathway. |
2008 |
J. Cell. Biochem. |
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Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer. |
2008 |
Int. J. Cancer |
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The class I histone deacetylases of the platyhelminth parasite Schistosoma mansoni. |
2008 |
Biochem. Biophys. Res. Commun. |
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Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells. |
2008 |
Clin Lung Cancer |
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HDAC inhibition upregulates the expression of angiostatic ADAMTS1. |
2008 |
FEBS Lett. |
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Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. |
2008 |
Pharm. Res. |
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Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors. |
2008 |
Cancer Res. |
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Mizumoto S et al. |
The developmental potential of parthenogenetic and somatic cell nuclear-transferred rat oocytes in vitro. |
2008 |
Cloning Stem Cells |
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Characterizing heterogeneous cellular responses to perturbations. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
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Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism. |
2008 |
BMC Genomics |
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Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. |
2008 |
Cell Stem Cell |
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Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs. |
2008 |
Br. J. Cancer |
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The Arabidopsis histone deacetylases HDA6 and HDA19 contribute to the repression of embryonic properties after germination. |
2008 |
Plant Physiol. |
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Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells. |
2008 |
Chromosoma |
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Effect of trichostatin a on viability and microRNA expression in human pancreatic cancer cell line BxPC-3. |
2008 |
Exp. Oncol. |
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Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to Trichostatin A and 1alpha,25-dihydroxyvitamin D3. |
2008 |
Nucleic Acids Res. |
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Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs). |
2008 |
Bioorg. Med. Chem. |
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Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. |
2008 |
Hepatology |
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Trichostatin A and nuclear reprogramming of cloned rabbit embryos. |
2008 |
J. Anim. Sci. |
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Histone deacetylase inhibitors: from bench to clinic. |
2008 |
J. Med. Chem. |
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HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity. |
2008 |
J. Biol. Chem. |
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BM88/Cend1 is involved in histone deacetylase inhibition-mediated growth arrest and differentiation of neuroblastoma cells. |
2008 |
FEBS Lett. |
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Trichostatin A regulates peroxiredoxin expression and virulence of the parasite Entamoeba histolytica. |
2008 |
Mol. Biochem. Parasitol. |
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Potent antimalarial activity of histone deacetylase inhibitor analogues. |
2008 |
Antimicrob. Agents Chemother. |
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Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells. |
2008 |
Cancer Res. |
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Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. |
2008 |
Immunology |
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HDAC inhibitors stimulate viral transcription by multiple mechanisms. |
2008 |
Virol. J. |
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Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin. |
2008 |
J. Cell. Sci. |
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Regulation of ER alpha signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90. |
2008 |
Neurochem. Res. |
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Homocysteine-induced extracellular superoxide dismutase and its epigenetic mechanisms in monocytes. |
2008 |
J. Exp. Biol. |
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Induction of apoptosis in renal tubular cells by histone deacetylase inhibitors, a family of anticancer agents. |
2008 |
J. Pharmacol. Exp. Ther. |
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Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion. |
2008 |
Mol. Cancer Res. |
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Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. |
2008 |
Neuro-oncology |
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Epigenetic remodeling during arsenical-induced malignant transformation. |
2008 |
Carcinogenesis |
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Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. |
2008 |
Microbiology (Reading, Engl.) |
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Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. |
2008 |
Oncol. Rep. |
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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
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Modulation of transcription parameters in glucocorticoid receptor-mediated repression. |
2008 |
Mol. Cell. Endocrinol. |
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Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. |
2008 |
Exp. Hematol. |
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[Kidney regeneration update]. |
2008 |
Nippon Rinsho |
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Trichostatin A improved epigenetic modifications of transfected cells but did not improve subsequent cloned embryo development. |
2008 |
Anim. Biotechnol. |
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Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. |
2008 |
Exp. Cell Res. |
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High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos. |
2008 |
Theriogenology |
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The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage. |
2008 |
BMB Rep |
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Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. |
2008 |
Eur. J. Pharmacol. |
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Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis. |
2008 |
Genome Biol. |
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Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. |
2008 |
J. Proteome Res. |
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HDAC2 deficiency and histone acetylation. |
2008 |
Nat. Genet. |
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Chromatin changes induced by lamin A/C deficiency and the histone deacetylase inhibitor trichostatin A. |
2008 |
Eur. J. Cell Biol. |
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Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. |
2008 |
Cancer Invest. |
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Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. |
2008 |
Int. J. Cancer |
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Nakao Y et al. |
Evaluation of antiangiogenic activity of azumamides by the in vitro vascular organization model using mouse induced pluripotent stem (iPS) cells. |
2008 |
Bioorg. Med. Chem. Lett. |
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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. |
2008 |
Bioorg. Med. Chem. Lett. |
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Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group. |
2008 |
Bioorg. Med. Chem. |
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Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. |
2008 |
J. Cell. Mol. Med. |
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Comparative molecular dynamics simulations of histone deacetylase-like protein: binding modes and free energy analysis to hydroxamic acid inhibitors. |
2008 |
Proteins |
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Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats. |
2008 |
J. Neurosci. |
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Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma. |
2008 |
Mol. Cancer Res. |
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Histone deacetylase 5 represses the transcription of cyclin D3. |
2008 |
J. Cell. Biochem. |
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Kawamoto K et al. |
DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines. |
2008 |
Int. J. Cancer |
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Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. |
2008 |
J. Biol. Chem. |
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The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. |
2008 |
J. Autoimmun. |
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Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. |
2008 |
Exp. Cell Res. |
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Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. |
2008 |
J. Leukoc. Biol. |
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[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. |
2008 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:18718068
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Gastric cancer cell lines induced by trichostatin A. |
2008 |
World J. Gastroenterol. |
pmid:18720545
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Duan H et al. |
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
2008 |
Oncogene |
pmid:18695675
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Ding X et al. |
Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. |
2008 |
Theriogenology |
pmid:18556056
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Epigenetic regulation of established human type 1 versus type 2 cytokine responses. |
2008 |
J. Allergy Clin. Immunol. |
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Schauber J et al. |
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. |
2008 |
J. Invest. Dermatol. |
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Chen J et al. |
Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis. |
2008 |
Chem. Biol. Interact. |
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Jin B et al. |
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. |
2008 |
Hum. Mol. Genet. |
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Gan Y et al. |
Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. |
2008 |
Biochem. Biophys. Res. Commun. |
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Lee EJ et al. |
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
2008 |
Int. J. Oncol. |
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Van Wagoner DR and Nattel S |
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18817781
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Hitchler MJ et al. |
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells. |
2008 |
Free Radic. Biol. Med. |
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