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Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
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Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. |
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Carcinogenesis |
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The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). |
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Curr. Med. Chem. |
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Science |
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Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1. |
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Regulation of the rat NHE3 gene promoter by sodium butyrate. |
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Am. J. Physiol. Gastrointest. Liver Physiol. |
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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. |
2001 |
Cancer Chemother. Pharmacol. |
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The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases. |
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Mol. Endocrinol. |
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The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells. |
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Trichostatin A inhibits beta-casein expression in mammary epithelial cells. |
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Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor. |
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Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. |
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Am. J. Hematol. |
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Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
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Nucleic Acids Res. |
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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. |
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Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. |
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Clin. Cancer Res. |
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Magdinier F and Wolffe AP |
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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A functionally active RARalpha nuclear receptor is expressed in retinoic acid non responsive early myeloblastic cell lines. |
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Negative regulation of bcl-2 expression by p53 in hematopoietic cells. |
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Oncogene |
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Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. |
2001 |
Thyroid |
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Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. |
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Int. J. Cancer |
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The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. |
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Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
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Oncogene |
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Increased transcription levels induce higher mutation rates in a hypermutating cell line. |
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Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells. |
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Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. |
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Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development. |
2001 |
Zygote |
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Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
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Griswold MD et al. |
Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells. |
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Mol. Cell. Endocrinol. |
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Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. |
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Mol. Cell. Biol. |
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The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression. |
2001 |
Mol. Endocrinol. |
pmid:11158338
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Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma. |
2001 |
Carcinogenesis |
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Inhibition of histone deacetylation induces constitutive derepression of the beta interferon promoter and confers antiviral activity. |
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J. Virol. |
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The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11238943
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Meier JL |
Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator. |
2001 |
J. Virol. |
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Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
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