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De novo protein synthesis is required for lytic cycle reactivation of Epstein-Barr virus, but not Kaposi's sarcoma-associated herpesvirus, in response to histone deacetylase inhibitors and protein kinase C agonists. |
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The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. |
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Cancer Biother. Radiopharm. |
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Aging Cell |
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2007 |
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Histone deacetylase inhibitors stimulate cell migration in human endometrial adenocarcinoma cells through up-regulation of glycodelin. |
2007 |
Endocrinology |
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Oncogene |
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Neoplasia |
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2007 |
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Cancer Res. |
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A functional link between rhythmic changes in chromatin structure and the Arabidopsis biological clock. |
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Plant Cell |
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The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model. |
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Br. J. Cancer |
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BMC Cancer |
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Oncogene |
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Oncogene |
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A metabolic screening study of trichostatin A (TSA) and TSA-like histone deacetylase inhibitors in rat and human primary hepatocyte cultures. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Hum. Mol. Genet. |
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Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction. |
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An epigenetic modifier results in improved in vitro blastocyst production after somatic cell nuclear transfer. |
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Cloning Stem Cells |
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Mol. Cell |
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CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease. |
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Histone deacetylase inhibition and progesterone act synergistically to stimulate baboon glycodelin gene expression. |
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Mol. Cancer Res. |
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Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. |
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Biochim. Biophys. Acta |
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The major histocompatibility complex class II transactivator is differentially regulated by interferon-gamma and transforming growth factor-beta in microglial cells. |
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NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. |
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Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1. |
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Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells. |
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Histone acetylation dependent allelic expression imbalance of BAPX1 in patients with the oculo-auriculo-vertebral spectrum. |
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Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors. |
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Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520. |
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Hum. Gene Ther. |
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[Anti-proliferative effect of histone deacetylase inhibitors on murine embryonic stem cells]. |
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Tsitologiia |
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Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. |
2006 |
Gastroenterology |
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Deacetylase inhibitors aid recovery in muscular dystrophy. |
2006 |
Lancet Neurol |
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Histone deacetylase activity is necessary for chromosome condensation during meiotic maturation in Xenopus laevis. |
2006 |
Chromosome Res. |
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Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. |
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Mol. Cell |
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Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes. |
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Toxicol. Sci. |
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Plakoglobin is differentially expressed in alveolar and embryonal rhabdomyosarcoma and is regulated by DNA methylation and histone acetylation. |
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Carcinogenesis |
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Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer. |
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J. Natl. Cancer Inst. |
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Mol. Cell. Biol. |
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Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. |
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Clin. Cancer Res. |
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The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis. |
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J. Mol. Endocrinol. |
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NF-kappaB activation upregulates fibroblast growth factor 8 expression in prostate cancer cells. |
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Prostate |
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Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. |
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Mol. Cancer Res. |
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MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. |
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Int. J. Cancer |
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Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. |
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Tubulin must be acetylated in order to form a complex with membrane Na(+),K (+)-ATPase and to inhibit its enzyme activity. |
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Mol. Cell. Biochem. |
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Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. |
2006 |
Circulation |
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Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. |
2006 |
Alcohol. Clin. Exp. Res. |
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Dynamic regulation of histone modifications in Xenopus oocytes through histone exchange. |
2006 |
Mol. Cell. Biol. |
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Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells. |
2006 |
Int. J. Cancer |
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5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation. |
2006 |
Leuk. Res. |
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Epigenetic regulation of lentiviral transgene vectors in a large animal model. |
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Mol. Ther. |
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Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. |
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J. Med. Chem. |
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NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. |
2006 |
Pharmacol. Res. |
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Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells. |
2006 |
Cancer Lett. |
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Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). |
2006 |
J. Atheroscler. Thromb. |
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Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression. |
2006 |
J. Leukoc. Biol. |
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Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. |
2006 |
Endocr. Relat. Cancer |
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Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy. |
2006 |
Mol. Hum. Reprod. |
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Chen J et al. |
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells. |
2006 |
Pharmazie |
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Kim MY et al. |
A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
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Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. |
2006 |
BMC Cancer |
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An ex vivo method for rapid generation of monoclonal antibodies (ADLib system). |
2006 |
Nat Protoc |
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Role of histone deacetylase in the expression of CTP:phosphocholine cytidylyltransferase alpha. |
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J. Biol. Chem. |
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Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
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Trichostatin A sensitizes TRAIL-resistant myeloma cells by downregulation of the antiapoptotic Bcl-2 proteins. |
2006 |
Cancer Chemother. Pharmacol. |
pmid:16435155
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Deng G et al. |
Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. |
2006 |
Int. J. Cancer |
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Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression. |
2006 |
Neurosci. Lett. |
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Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53. |
2006 |
Clin. Cancer Res. |
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Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. |
2006 |
Clin. Gastroenterol. Hepatol. |
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