Yoshida M et al. |
Histone deacetylase as a new target for cancer chemotherapy. |
2001 |
Cancer Chemother. Pharmacol. |
pmid:11587361
|
Jung M |
Inhibitors of histone deacetylase as new anticancer agents. |
2001 |
Curr. Med. Chem. |
pmid:11562279
|
Ashburner BP et al. |
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. |
2001 |
Mol. Cell. Biol. |
pmid:11564889
|
Sachs LM et al. |
Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis. |
2001 |
Dev. Dyn. |
pmid:11668605
|
Amann JM et al. |
ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. |
2001 |
Mol. Cell. Biol. |
pmid:11533236
|
Walker GE et al. |
Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
pmid:11517158
|
Jorgensen JS and Nilson JH |
AR suppresses transcription of the alpha glycoprotein hormone subunit gene through protein-protein interactions with cJun and activation transcription factor 2. |
2001 |
Mol. Endocrinol. |
pmid:11518798
|
Phiel CJ et al. |
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
2001 |
J. Biol. Chem. |
pmid:11473107
|
Sundqvist A et al. |
Functional knockout of the corepressor CtBP by the second exon of adenovirus E1a relieves repression of transcription. |
2001 |
Exp. Cell Res. |
pmid:11478854
|
Jacob AL et al. |
Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. |
2001 |
J. Biol. Chem. |
pmid:11479297
|
Li J et al. |
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
2001 |
Mol. Cell. Biol. |
pmid:11689710
|
Hirschler-Laszkiewicz I et al. |
The role of acetylation in rDNA transcription. |
2001 |
Nucleic Acids Res. |
pmid:11600700
|
Wang H et al. |
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
2001 |
Science |
pmid:11387442
|
Klar AJ et al. |
A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
pmid:11404352
|
Massa S et al. |
3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. |
2001 |
J. Med. Chem. |
pmid:11405644
|
Setlow JK et al. |
Evidence for gene silencing in Haemophilus influenzae. |
2001 |
Mutat. Res. |
pmid:11406170
|
Singal R et al. |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. |
2001 |
Cancer Res. |
pmid:11406558
|
Baur JA et al. |
Telomere position effect in human cells. |
2001 |
Science |
pmid:11408657
|
Zelivianski S et al. |
Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype. |
2001 |
Biochim. Biophys. Acta |
pmid:11389966
|
Feng YQ et al. |
Position effects are influenced by the orientation of a transgene with respect to flanking chromatin. |
2001 |
Mol. Cell. Biol. |
pmid:11113204
|
Harada Y et al. |
A hematopoietic-specific transmembrane protein, Art-1, is possibly regulated by AML1. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11396961
|
Mehra-Chaudhary R et al. |
Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. |
2001 |
Biochem. J. |
pmid:11115394
|
Meier JL |
Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator. |
2001 |
J. Virol. |
pmid:11160656
|
Kuusisto E et al. |
Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11162503
|
Grandjean V et al. |
Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. |
2001 |
FEBS Lett. |
pmid:11163765
|
Lizcano F et al. |
Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11165035
|
Nervi C et al. |
Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity. |
2001 |
Cancer Res. |
pmid:11245412
|
Zhu WG et al. |
DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. |
2001 |
Cancer Res. |
pmid:11245429
|
Muth V et al. |
Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. |
2001 |
EMBO J. |
pmid:11250901
|
Rombouts K et al. |
Trichostatin A, lead compound for development of antifibrogenic drugs. |
2001 Jul-Sep |
Acta Gastroenterol. Belg. |
pmid:11680040
|
McGuinness MC et al. |
Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
2001 Sep-Oct |
Mol. Genet. Metab. |
pmid:11592822
|
Wilson MA et al. |
The histone deacetylase inhibitor trichostatin A blocks progesterone receptor-mediated transactivation of the mouse mammary tumor virus promoter in vivo. |
2002 |
J. Biol. Chem. |
pmid:11821430
|
Deroanne CF et al. |
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. |
2002 |
Oncogene |
pmid:11821955
|
Zhang W and Kone BC |
NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: role of histone deacetylases. |
2002 |
Am. J. Physiol. Renal Physiol. |
pmid:12372765
|
Handumrongkul C et al. |
Distinct sets of cellular genes control the expression of transfected, nuclear-localized genes. |
2002 |
Mol. Ther. |
pmid:11829526
|
Ailenberg M and Silverman M |
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12379227
|
Yamashita K et al. |
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. |
2002 |
Cancer Cell |
pmid:12498717
|
Fahrner JA et al. |
Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. |
2002 |
Cancer Res. |
pmid:12499261
|
Rombouts K et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses collagen synthesis and prevents TGF-beta(1)-induced fibrogenesis in skin fibroblasts. |
2002 |
Exp. Cell Res. |
pmid:12169274
|
Waterborg JH and Kapros T |
Kinetic analysis of histone acetylation turnover and Trichostatin A induced hyper- and hypoacetylation in alfalfa. |
2002 |
Biochem. Cell Biol. |
pmid:12123281
|
Nair RR et al. |
Enhancement of transgene expression by combining glucocorticoids and anti-mitotic agents during transient transfection using DNA-cationic liposomes. |
2002 |
Mol. Ther. |
pmid:11945073
|
Qiu P and Li L |
Histone acetylation and recruitment of serum responsive factor and CREB-binding protein onto SM22 promoter during SM22 gene expression. |
2002 |
Circ. Res. |
pmid:11988486
|
Mai A et al. |
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. |
2002 |
J. Med. Chem. |
pmid:11960489
|
Merezak C et al. |
Inhibition of histone deacetylases induces bovine leukemia virus expression in vitro and in vivo. |
2002 |
J. Virol. |
pmid:11967319
|
Scott GK et al. |
Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen. |
2002 |
Mol. Cancer Ther. |
pmid:12477051
|
Travers H et al. |
Human CD34+ hematopoietic progenitor cells hyperacetylate core histones in response to sodium butyrate, but not trichostatin A. |
2002 |
Exp. Cell Res. |
pmid:12413881
|
Wilson AJ et al. |
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. |
2002 |
Cancer Res. |
pmid:12414619
|
Choy JS and Kron SJ |
NuA4 subunit Yng2 function in intra-S-phase DNA damage response. |
2002 |
Mol. Cell. Biol. |
pmid:12417725
|
Ghoshal K et al. |
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. |
2002 |
Mol. Cell. Biol. |
pmid:12417732
|
Hauser C et al. |
Activation of the mouse histone deacetylase 1 gene by cooperative histone phosphorylation and acetylation. |
2002 |
Mol. Cell. Biol. |
pmid:12391151
|