Hutt DM et al. |
Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ΔF508-CFTR. |
2011 |
ACS Med Chem Lett |
pmid:21984958
|
Lopez-Atalaya JP et al. |
Histone acetylation deficits in lymphoblastoid cell lines from patients with Rubinstein-Taybi syndrome. |
2012 |
J. Med. Genet. |
pmid:21984751
|
Deckmann K et al. |
Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1. |
2012 |
Cell. Signal. |
pmid:21983014
|
Ohtani K et al. |
Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells. |
2011 |
Circ. Res. |
pmid:21980126
|
Balsas P et al. |
Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy. |
2012 |
Leuk. Res. |
pmid:21978467
|
Mostovich LA et al. |
Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors. |
2011 Sep-Oct |
Cell Adh Migr |
pmid:21975548
|
Rhodes LV et al. |
The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells. |
2012 |
Oncol. Rep. |
pmid:21971930
|
Lee TB et al. |
Histone H4 deacetylation down-regulates catalase gene expression in doxorubicin-resistant AML subline. |
2012 |
Cell Biol. Toxicol. |
pmid:21968610
|
Wang W et al. |
The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression. |
2012 |
Nucleic Acids Res. |
pmid:21967847
|
Arany I et al. |
Epigenetic modifiers exert renal toxicity through induction of p66shc. |
2011 |
Anticancer Res. |
pmid:21965735
|
Tsai KW et al. |
Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. |
2011 |
Int. J. Cancer |
pmid:21960261
|
Icardi L et al. |
Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2. |
2012 |
FASEB J. |
pmid:21957129
|
Majumdar G et al. |
Panhistone deacetylase inhibitors inhibit proinflammatory signaling pathways to ameliorate interleukin-18-induced cardiac hypertrophy. |
2011 |
Physiol. Genomics |
pmid:21954451
|
Dehnugara T et al. |
An in vitro, short-term culture method for mammalian haploid round spermatids amenable for molecular manipulation. |
2012 |
Mol. Reprod. Dev. |
pmid:21953649
|
Grabiec AM et al. |
Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay. |
2012 |
Ann. Rheum. Dis. |
pmid:21953341
|
Gillespie J et al. |
Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients. |
2012 |
Arthritis Rheum. |
pmid:21952924
|
Meester-Smoor MA et al. |
The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation. |
2011 |
PLoS ONE |
pmid:21949683
|
Ekici M et al. |
Chromatin structure and expression of the AMPA receptor subunit Glur2 in human glioma cells: major regulatory role of REST and Sp1. |
2012 |
J. Cell. Biochem. |
pmid:21948504
|
Kadaja-Saarepuu L et al. |
Tumor suppressor p53 down-regulates expression of human leukocyte marker CD43 in non-hematopoietic tumor cells. |
2012 |
Int. J. Oncol. |
pmid:21947346
|
Yang G et al. |
Trichostatin a promotes cardiomyocyte differentiation of rat mesenchymal stem cells after 5-azacytidine induction or during coculture with neonatal cardiomyocytes via a mechanism independent of histone deacetylase inhibition. |
2012 |
Cell Transplant |
pmid:21944777
|
Jeon HG et al. |
Induction of caspase mediated apoptosis and down-regulation of nuclear factor-κB and Akt signaling are involved in the synergistic antitumor effect of gemcitabine and the histone deacetylase inhibitor trichostatin A in human bladder cancer cells. |
2011 |
J. Urol. |
pmid:21944112
|
Chen S et al. |
[Effect of trichostatin alone and combination with imatinb on the proliferation and apoptosis of the K562R cells]. |
2011 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:21937807
|
Li L et al. |
Use of mouse hematopoietic stem and progenitor cells to treat acute kidney injury. |
2012 |
Am. J. Physiol. Renal Physiol. |
pmid:21937606
|
Jafarpour F et al. |
Somatic cell-induced hyperacetylation, but not hypomethylation, positively and reversibly affects the efficiency of in vitro cloned blastocyst production in cattle. |
2011 |
Cell Reprogram |
pmid:21919704
|
Li L et al. |
Regulation of histone acetylation by NDRG2 in glioma cells. |
2012 |
J. Neurooncol. |
pmid:21912936
|
Hsu YF et al. |
MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide. |
2011 |
Biochim. Biophys. Acta |
pmid:21911040
|
Maruoka H et al. |
Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons. |
2011 |
J. Biochem. |
pmid:21908547
|
Zhu L et al. |
Hyperoxia arrests alveolar development through suppression of histone deacetylases in neonatal rats. |
2012 |
Pediatr. Pulmonol. |
pmid:21905265
|
Wang JP et al. |
Recapitulation of fibromatosis nodule by multipotential stem cells in immunodeficient mice. |
2011 |
PLoS ONE |
pmid:21901157
|
Fan LX et al. |
Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation. |
2012 |
Kidney Int. |
pmid:21900881
|
Atanackovic D et al. |
Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia. |
2011 |
Am. J. Hematol. |
pmid:21898529
|
Crandall JE et al. |
Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex. |
2011 |
J. Neurochem. |
pmid:21895658
|
Pufahl L et al. |
Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3. |
2012 |
J. Cell. Mol. Med. |
pmid:21883892
|
Rajak H et al. |
2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21875796
|
Oliveira CS et al. |
Supplementation with the histone deacetylase inhibitor trichostatin A during in vitro culture of bovine embryos. |
2013 |
Zygote |
pmid:21867598
|
Tong Y et al. |
PTTG1 attenuates drug-induced cellular senescence. |
2011 |
PLoS ONE |
pmid:21858218
|
Mayor R et al. |
Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. |
2011 |
Epigenetics |
pmid:21852760
|
Meng CF et al. |
DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells. |
2011 Nov-Dec |
Mol Med Rep |
pmid:21850374
|
Costa VL et al. |
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers. |
2011 |
Epigenetics |
pmid:21847011
|
Yu D et al. |
Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21840716
|
Sahu GK and Cloyd MW |
Latent HIV in primary T lymphocytes is unresponsive to histone deacetylase inhibitors. |
2011 |
Virol. J. |
pmid:21838863
|
Xiao J et al. |
Discovery, synthesis, and biological evaluation of novel SMN protein modulators. |
2011 |
J. Med. Chem. |
pmid:21819082
|
Kumar A et al. |
γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines. |
2011 |
Int. J. Radiat. Biol. |
pmid:21815748
|
Hu Y et al. |
Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize. |
2011 |
PLoS ONE |
pmid:21811564
|
Klawitter M et al. |
Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration. |
2011 |
J Negat Results Biomed |
pmid:21801383
|
Rajasingh J et al. |
Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells. |
2011 |
PLoS ONE |
pmid:21799893
|
Arzenani MK et al. |
Genomic DNA hypomethylation by histone deacetylase inhibition implicates DNMT1 nuclear dynamics. |
2011 |
Mol. Cell. Biol. |
pmid:21791605
|
Amoêdo ND et al. |
Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. |
2011 |
PLoS ONE |
pmid:21789245
|
Bence M et al. |
Transcriptional modulation of monoaminergic neurotransmission genes by the histone deacetylase inhibitor trichostatin A in neuroblastoma cells. |
2012 |
J Neural Transm |
pmid:21785940
|
Zhou S et al. |
Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. |
2011 |
Circ. Res. |
pmid:21778425
|
Tost J et al. |
Methylation of specific CpG sites in the P2 promoter of parathyroid hormone-related protein determines the invasive potential of breast cancer cell lines. |
2011 |
Epigenetics |
pmid:21775817
|
Zhu K et al. |
Expression characterization and the promoter activity analysis of zebrafish hdac4. |
2012 |
Fish Physiol. Biochem. |
pmid:21773810
|
Watanabe Y and Tanaka M |
p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate. |
2011 |
J. Cell. Sci. |
pmid:21771882
|
Kee HJ et al. |
Trichostatin A prevents neointimal hyperplasia via activation of Krüppel like factor 4. |
2011 Nov-Dec |
Vascul. Pharmacol. |
pmid:21763782
|
Wan Y et al. |
Transcriptome profiling reveals a novel role for trichostatin A in antagonizing histone chaperone Chz1 mediated telomere anti-silencing. |
2011 |
FEBS Lett. |
pmid:21763693
|
Blanquart C et al. |
Pharmacological characterization of histone deacetylase inhibitor and tumor cell-growth inhibition properties of new benzofuranone compounds. |
2011 |
Curr Cancer Drug Targets |
pmid:21762083
|
Inoue H et al. |
Analysis of expression and structure of the rat GH-secretagogue/ghrelin receptor (Ghsr) gene: roles of epigenetic modifications in transcriptional regulation. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21756973
|
Huang KT et al. |
Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer. |
2011 |
Breast Cancer Res. Treat. |
pmid:21755341
|
Bui HT et al. |
Histone deacetylase inhibition improves activation of ribosomal RNA genes and embryonic nucleolar reprogramming in cloned mouse embryos. |
2011 |
Biol. Reprod. |
pmid:21753193
|
SustáÄková G et al. |
Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin. |
2012 |
J. Cell. Physiol. |
pmid:21732356
|
Whitehead L et al. |
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors. |
2011 |
Bioorg. Med. Chem. |
pmid:21723733
|
Gómez MC et al. |
Trichostatin A modified histone covalent pattern and enhanced expression of pluripotent genes in interspecies black-footed cat cloned embryos but did not improve in vitro and in vivo viability. |
2011 |
Cell Reprogram |
pmid:21718106
|
Yoo YE and Ko CP |
Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis. |
2011 |
Exp. Neurol. |
pmid:21712032
|
Hauff KD et al. |
Mifepristone treatment results in differential regulation of glycerolipid biosynthesis in baby hamster kidney cells expressing a mifepristone-inducible ABCA1. |
2011 |
Lipids |
pmid:21710238
|
Song K et al. |
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer. |
2011 |
Cancer Biol. Ther. |
pmid:21709440
|
Gaub P et al. |
The histone acetyltransferase p300 promotes intrinsic axonal regeneration. |
2011 |
Brain |
pmid:21705428
|
Chik CL et al. |
Histone modifications on the adrenergic induction of type II deiodinase in rat pinealocytes. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21704117
|
Kojima S et al. |
Asymmetric leaves2 and Elongator, a histone acetyltransferase complex, mediate the establishment of polarity in leaves of Arabidopsis thaliana. |
2011 |
Plant Cell Physiol. |
pmid:21700721
|
Cosner CC and Helquist P |
Concise, convergent syntheses of (±)-trichostatin A utilizing a Pd-catalyzed ketone enolate α-alkenylation reaction. |
2011 |
Org. Lett. |
pmid:21688856
|
Sar P et al. |
3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements. |
2011 |
PLoS ONE |
pmid:21687737
|
Zhang L et al. |
ABA treatment of germinating maize seeds induces VP1 gene expression and selective promoter-associated histone acetylation. |
2011 |
Physiol Plant |
pmid:21679193
|
Dávalos-Salas M et al. |
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. |
2011 |
BMC Cancer |
pmid:21663659
|
Cowell IG et al. |
Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin. |
2011 Jan-Feb |
Nucleus |
pmid:21647300
|
Acun T et al. |
SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. |
2011 |
BMC Cancer |
pmid:21645397
|
Seo SK et al. |
Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. |
2011 |
J Thorac Oncol |
pmid:21642861
|
Xia B et al. |
Chromium(VI) causes down regulation of biotinidase in human bronchial epithelial cells by modifications of histone acetylation. |
2011 |
Toxicol. Lett. |
pmid:21641978
|
Wong CY et al. |
Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells. |
2011 |
J. Biol. Chem. |
pmid:21636851
|
Jugová A et al. |
Effects of epigenetic-based anti-cancer drugs in leukaemia and multiple myeloma cells. |
2011 |
Cell Biol. Int. |
pmid:21635225
|
Lin S et al. |
HIV-1 reactivation induced by apicidin involves histone modification in latently infected cells. |
2011 |
Curr. HIV Res. |
pmid:21631428
|
Hou J et al. |
Structure-based optimization of click-based histone deacetylase inhibitors. |
2011 |
Eur J Med Chem |
pmid:21621883
|
Puppin C et al. |
Histone deacetylase inhibitors induce thymidine phosphorylase expression in cultured breast cancer cell lines. |
2011 |
Oncol. Rep. |
pmid:21617864
|
Selinger CI et al. |
Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. |
2011 |
J Thorac Oncol |
pmid:21597389
|
Misaki K et al. |
Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice. |
2011 |
Arthritis Res. Ther. |
pmid:21592365
|
Ververis K et al. |
Histone deacetylase inhibitors augment doxorubicin-induced DNA damage in cardiomyocytes. |
2011 |
Cell. Mol. Life Sci. |
pmid:21584806
|
Hawk JD et al. |
Post-training intrahippocampal inhibition of class I histone deacetylases enhances long-term object-location memory. |
2011 |
Learn. Mem. |
pmid:21576516
|
Bouquet F et al. |
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia. |
2011 |
J. Cell. Sci. |
pmid:21576354
|
Hayashi-Takanaka Y et al. |
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. |
2011 |
Nucleic Acids Res. |
pmid:21576221
|
Meng Y et al. |
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. |
2011 |
Dig. Dis. Sci. |
pmid:21567192
|
Vassiliev I et al. |
Isolation and in vitro characterization of putative porcine embryonic stem cells from cloned embryos treated with trichostatin A. |
2011 |
Cell Reprogram |
pmid:21548828
|
Neelarapu R et al. |
Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole- and pyrazole-based histone deacetylase probes. |
2011 |
J. Med. Chem. |
pmid:21548582
|
Vojdani Z et al. |
Cardiomyocyte marker expression in a human lymphocyte cell line using mouse cardiomyocyte extract. |
2011 |
Hum. Cell |
pmid:21547694
|
Shu G et al. |
Zac1 is a histone acetylation-regulated NF-κB suppressor that mediates histone deacetylase inhibitor-induced apoptosis. |
2011 |
Cell Death Differ. |
pmid:21546906
|
Kong Q et al. |
Effect of trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells. |
2011 |
Mol. Cell. Biochem. |
pmid:21541675
|
Qiu GH et al. |
Recognition and suppression of transfected plasmids by protein ZNF511-PRAP1, a potential molecular barrier to transgene expression. |
2011 |
Mol. Ther. |
pmid:21540836
|
Ramsey MR et al. |
Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma. |
2011 |
Cancer Res. |
pmid:21527555
|
Xiong H et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells. |
2012 |
Mol. Carcinog. |
pmid:21520296
|
Fortson WS et al. |
Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. |
2011 |
Int. J. Oncol. |
pmid:21519790
|
Crump NT et al. |
Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21518915
|
Nishikata I et al. |
Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation. |
2011 |
Oncogene |
pmid:21516122
|
Bolleyn J et al. |
Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes. |
2011 |
Toxicol In Vitro |
pmid:21513791
|