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Cancer Res. |
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Am. J. Physiol. Renal Physiol. |
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Tsitologiia |
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Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors. |
2011 Sep-Oct |
Cell Adh Migr |
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2011 Oct-Dec |
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DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells. |
2011 Nov-Dec |
Mol Med Rep |
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Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin. |
2011 Jan-Feb |
Nucleus |
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Effect of trichostatin A on transfected donor cells and subsequent development of porcine cloned embryos. |
2011 |
Zygote |
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Panhistone deacetylase inhibitors inhibit proinflammatory signaling pathways to ameliorate interleukin-18-induced cardiac hypertrophy. |
2011 |
Physiol. Genomics |
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Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. |
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Int. J. Cancer |
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Int. J. Cancer |
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Circ. Res. |
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2011 |
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HDAC activity is required during Xenopus tail regeneration. |
2011 |
PLoS ONE |
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2011 |
PLoS ONE |
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Unsaturated fatty acids repress the expression of adipocyte fatty acid binding protein via the modulation of histone deacetylation in RAW 264.7 macrophages. |
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Eur J Nutr |
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Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells. |
2011 |
Eur J Med Chem |
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2011 |
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2011 |
Theriogenology |
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Trichostatin A-treated eight-cell bovine embryos had increased histone acetylation and gene expression, with increased cell numbers at the blastocyst stage. |
2011 |
Theriogenology |
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Chromium(VI) causes down regulation of biotinidase in human bronchial epithelial cells by modifications of histone acetylation. |
2011 |
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Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. |
2011 |
J Thorac Oncol |
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SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. |
2011 |
BMC Cancer |
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2011 |
Eur J Med Chem |
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2011 |
J. Biol. Rhythms |
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The histone acetyltransferase p300 promotes intrinsic axonal regeneration. |
2011 |
Brain |
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2011 |
Cancer Biol. Ther. |
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Classical Hodgkin's lymphoma shows epigenetic features of abortive plasma cell differentiation. |
2011 |
Haematologica |
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Effects of alcohol on histone deacetylase 2 (HDAC2) and the neuroprotective role of trichostatin A (TSA). |
2011 |
Alcohol. Clin. Exp. Res. |
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ERK1/2 activation plays important roles in the opposite effects of Trichostatin A in non-cancer and cancer cells. |
2011 |
Toxicon |
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[Trichostatin A inhibits the activation of CD(4)(+) T cells by suppressing CD(28) expression in mice]. |
2011 |
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2011 |
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Trichostatin A inhibits collagen synthesis and induces apoptosis in keloid fibroblasts. |
2011 |
Arch. Dermatol. Res. |
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Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation. |
2011 |
Endocrinology |
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Mouse embryonic stem cells inhibit murine cytomegalovirus infection through a multi-step process. |
2011 |
PLoS ONE |
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Epigenetic inactivation of PCDH10 in human prostate cancer cell lines. |
2011 |
Cell Biol. Int. |
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HIV-1 Tat upregulates expression of histone deacetylase-2 (HDAC2) in human neurons: implication for HIV-associated neurocognitive disorder (HAND). |
2011 |
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Synergistic efficacy in human ovarian cancer cells by histone deacetylase inhibitor TSA and proteasome inhibitor PS-341. |
2011 |
Cancer Invest. |
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DeltaNp63, a target of DEC1 and histone deacetylase 2, modulates the efficacy of histone deacetylase inhibitors in growth suppression and keratinocyte differentiation. |
2011 |
J. Biol. Chem. |
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Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis. |
2011 |
PLoS ONE |
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Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. |
2011 |
Mod. Pathol. |
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Trichostatin differentially regulates Th1 and Th2 responses and alleviates rheumatoid arthritis in mice. |
2011 |
J. Clin. Immunol. |
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Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells. |
2011 |
Int. J. Oncol. |
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Human parthenogenetic stem cells produce enriched populations of definitive endoderm cells after trichostatin A pretreatment. |
2011 |
Differentiation |
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Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation. |
2011 |
Oncogene |
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Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
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Histone deacetylase inhibition improves activation of ribosomal RNA genes and embryonic nucleolar reprogramming in cloned mouse embryos. |
2011 |
Biol. Reprod. |
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Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. |
2011 |
Int. J. Oncol. |
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Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer. |
2011 |
Breast Cancer Res. Treat. |
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Analysis of expression and structure of the rat GH-secretagogue/ghrelin receptor (Ghsr) gene: roles of epigenetic modifications in transcriptional regulation. |
2011 |
Mol. Cell. Endocrinol. |
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The effects of 5-aza-2'- deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts. |
2011 |
Cell Reprogram |
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p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate. |
2011 |
J. Cell. Sci. |
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Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. |
2011 |
Cancer Sci. |
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Histone deacetylase 1 (HDAC1) participates in the down-regulation of corticotropin releasing hormone gene (crh) expression. |
2011 |
Physiol. Behav. |
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Methylation of specific CpG sites in the P2 promoter of parathyroid hormone-related protein determines the invasive potential of breast cancer cell lines. |
2011 |
Epigenetics |
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Sp1 is a transcription repressor to stanniocalcin-1 expression in TSA-treated human colon cancer cells, HT29. |
2011 |
J. Cell. Biochem. |
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Pharmacological characterization of histone deacetylase inhibitor and tumor cell-growth inhibition properties of new benzofuranone compounds. |
2011 |
Curr Cancer Drug Targets |
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Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins. |
2011 |
J. Cell. Biochem. |
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Transcriptome profiling reveals a novel role for trichostatin A in antagonizing histone chaperone Chz1 mediated telomere anti-silencing. |
2011 |
FEBS Lett. |
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Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300. |
2011 |
J Toxicol Sci |
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Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. |
2011 |
Apoptosis |
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Hu Y et al. |
Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize. |
2011 |
PLoS ONE |
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Chen YT et al. |
Isolation of mesenchymal stem cells from human ligamentum flavum: implicating etiology of ligamentum flavum hypertrophy. |
2011 |
Spine |
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Trichostatin A promotes the development of bovine somatic cell nuclear transfer embryos. |
2011 |
J. Reprod. Dev. |
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Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. |
2011 |
PLoS ONE |
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Genomic DNA hypomethylation by histone deacetylase inhibition implicates DNMT1 nuclear dynamics. |
2011 |
Mol. Cell. Biol. |
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Involvement of histone acetylation of Sox17 and Foxa2 promoters during mouse definitive endoderm differentiation revealed by microRNA profiling. |
2011 |
PLoS ONE |
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Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats. |
2011 |
Am. J. Respir. Crit. Care Med. |
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Histone deacetylase inhibitors block nuclear factor-κB-dependent transcription by interfering with RNA polymerase II recruitment. |
2011 |
Cancer Sci. |
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[Effect of trichostatin alone and combination with imatinb on the proliferation and apoptosis of the K562R cells]. |
2011 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
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Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines. |
2011 |
HBPD INT |
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HDAC activity is required for efficient core promoter function at the mouse mammary tumor virus promoter. |
2011 |
J. Biomed. Biotechnol. |
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Trichostatin A inhibits expression of cathepsins in experimental osteoarthritis. |
2011 |
Rheumatol. Int. |
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The histone deacetylase inhibitor trichostatin A synergistically resensitizes a cisplatin resistant human bladder cancer cell line. |
2011 |
J. Urol. |
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Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors. |
2011 |
Bioorg. Med. Chem. Lett. |
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Inhibition of histone deacetylase causes emphysema. |
2011 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Pluripotency maintenance in mouse somatic cell nuclear transfer embryos and its improvement by treatment with the histone deacetylase inhibitor TSA. |
2011 |
Cell Reprogram |
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Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer. |
2011 |
Am. J. Pathol. |
pmid:21281785
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Puppin C et al. |
In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription. |
2011 |
Cell Oncol (Dordr) |
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Cutting edge: tubulin α functions as an adaptor in NFAT-importin β interaction. |
2011 |
J. Immunol. |
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Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy. |
2011 |
Cancer |
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Trichostatin A modified histone covalent pattern and enhanced expression of pluripotent genes in interspecies black-footed cat cloned embryos but did not improve in vitro and in vivo viability. |
2011 |
Cell Reprogram |
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Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. |
2011 |
Dig. Dis. Sci. |
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Histone deacetylase inhibitors induce thymidine phosphorylase expression in cultured breast cancer cell lines. |
2011 |
Oncol. Rep. |
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Zac1 is a histone acetylation-regulated NF-κB suppressor that mediates histone deacetylase inhibitor-induced apoptosis. |
2011 |
Cell Death Differ. |
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Cardiomyocyte marker expression in a human lymphocyte cell line using mouse cardiomyocyte extract. |
2011 |
Hum. Cell |
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Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole- and pyrazole-based histone deacetylase probes. |
2011 |
J. Med. Chem. |
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Isolation and in vitro characterization of putative porcine embryonic stem cells from cloned embryos treated with trichostatin A. |
2011 |
Cell Reprogram |
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Histone deacetylase inhibitors augment doxorubicin-induced DNA damage in cardiomyocytes. |
2011 |
Cell. Mol. Life Sci. |
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Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice. |
2011 |
Arthritis Res. Ther. |
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Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. |
2011 |
J Thorac Oncol |
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