Park H et al. |
Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells. |
2008 |
Int. J. Mol. Med. |
pmid:18949380
|
Lin YC et al. |
Effects of trichostatin A on neuronal mu-opioid receptor gene expression. |
2008 |
Brain Res. |
pmid:18950606
|
Haffner I et al. |
Regulation of arginase-1 expression in macrophages by a protein kinase A type I and histone deacetylase dependent pathway. |
2008 |
J. Cell. Biochem. |
pmid:17577214
|
Dowling DP et al. |
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. |
2008 |
Biochemistry |
pmid:19053282
|
Ishii T et al. |
[Epigenetic regulation in alcohol-related brain damage]. |
2008 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
pmid:19068777
|
Gray SG et al. |
Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells. |
2008 |
Clin Lung Cancer |
pmid:19073520
|
Zhu K et al. |
Telomerase expression and cell proliferation in ovarian cancer cells induced by histone deacetylase inhibitors. |
2008 |
Arch. Gynecol. Obstet. |
pmid:17680259
|
Chou CW and Chen CC |
HDAC inhibition upregulates the expression of angiostatic ADAMTS1. |
2008 |
FEBS Lett. |
pmid:19007777
|
Nair S et al. |
Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. |
2008 |
Pharm. Res. |
pmid:17657594
|
Setiadi AF et al. |
Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors. |
2008 |
Cancer Res. |
pmid:19047136
|
Mizumoto S et al. |
The developmental potential of parthenogenetic and somatic cell nuclear-transferred rat oocytes in vitro. |
2008 |
Cloning Stem Cells |
pmid:19049415
|
Slack MD et al. |
Characterizing heterogeneous cellular responses to perturbations. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19052231
|
Chittur SV et al. |
Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism. |
2008 |
BMC Genomics |
pmid:18959802
|
Meng CF et al. |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP]. |
2008 |
Ai Zheng |
pmid:19079988
|
Usami M et al. |
Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. |
2008 |
Nutr Res |
pmid:19083427
|
Krämer OH et al. |
Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis. |
2008 |
Oncogene |
pmid:17653085
|
Tanaka M et al. |
The Arabidopsis histone deacetylases HDA6 and HDA19 contribute to the repression of embryonic properties after germination. |
2008 |
Plant Physiol. |
pmid:18024558
|
Ramirez T et al. |
Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells. |
2008 |
Chromosoma |
pmid:17999076
|
Malinen M et al. |
Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to Trichostatin A and 1alpha,25-dihydroxyvitamin D3. |
2008 |
Nucleic Acids Res. |
pmid:17999998
|
Nasu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model. |
2008 |
Osteoarthr. Cartil. |
pmid:18226559
|
Lim HG et al. |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. |
2008 |
Mol. Ther. |
pmid:18227841
|
Ruau D et al. |
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. |
2008 |
Stem Cells |
pmid:18203677
|
Serrano E et al. |
Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. |
2008 |
Leuk. Res. |
pmid:18206229
|
Hamner JB et al. |
The efficacy of combination therapy using adeno-associated virus--interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma. |
2008 |
J. Pediatr. Surg. |
pmid:18206478
|
Duhamel M et al. |
Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. |
2008 |
FEBS Lett. |
pmid:18206652
|
Joseph RA et al. |
Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. |
2008 |
Hepatology |
pmid:18161881
|
Shi LH et al. |
Trichostatin A and nuclear reprogramming of cloned rabbit embryos. |
2008 |
J. Anim. Sci. |
pmid:18245503
|
Paris M et al. |
Histone deacetylase inhibitors: from bench to clinic. |
2008 |
J. Med. Chem. |
pmid:18247554
|
Gupta MP et al. |
HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity. |
2008 |
J. Biol. Chem. |
pmid:18250163
|
Politis PK et al. |
BM88/Cend1 is involved in histone deacetylase inhibition-mediated growth arrest and differentiation of neuroblastoma cells. |
2008 |
FEBS Lett. |
pmid:18258204
|
Isakov E et al. |
Trichostatin A regulates peroxiredoxin expression and virulence of the parasite Entamoeba histolytica. |
2008 |
Mol. Biochem. Parasitol. |
pmid:18191469
|
Campanero MR et al. |
The histone deacetylase inhibitor trichostatin A induces GADD45 gamma expression via Oct and NF-Y binding sites. |
2008 |
Oncogene |
pmid:17724474
|
Manning J et al. |
Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. |
2008 |
Immunology |
pmid:17725605
|
Balakrishnan L and Milavetz B |
HDAC inhibitors stimulate viral transcription by multiple mechanisms. |
2008 |
Virol. J. |
pmid:18353181
|
Pan J et al. |
TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. |
2008 |
Mol. Cancer Res. |
pmid:18505930
|
Kimata Y et al. |
Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin. |
2008 |
J. Cell. Sci. |
pmid:18354085
|
Hou J et al. |
Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation. |
2008 |
BMC Dev. Biol. |
pmid:18507869
|
Suuronen T et al. |
Regulation of ER alpha signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90. |
2008 |
Neurochem. Res. |
pmid:18307035
|
Dalgard CL et al. |
Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma. |
2008 |
Clin. Cancer Res. |
pmid:18483379
|
Jiang Y et al. |
Homocysteine-induced extracellular superoxide dismutase and its epigenetic mechanisms in monocytes. |
2008 |
J. Exp. Biol. |
pmid:18310117
|
Egler V et al. |
Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death. |
2008 |
Clin. Cancer Res. |
pmid:18483381
|
Chen Y et al. |
A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum. |
2008 |
J. Med. Chem. |
pmid:18494463
|
Sun C and Zhou J |
Trichostatin A improves insulin stimulated glucose utilization and insulin signaling transduction through the repression of HDAC2. |
2008 |
Biochem. Pharmacol. |
pmid:18495085
|
Ma P and Schultz RM |
Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos. |
2008 |
Dev. Biol. |
pmid:18501342
|
Kikuno N et al. |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. |
2008 |
Int. J. Cancer |
pmid:18431742
|
Zhang HJ et al. |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. |
2008 |
Placenta |
pmid:18440631
|
Meja KK et al. |
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. |
2008 |
Am. J. Respir. Cell Mol. Biol. |
pmid:18421014
|
Sebastián C et al. |
Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells. |
2008 |
J. Immunol. |
pmid:18424709
|
Sun Y et al. |
Modulation of transcription parameters in glucocorticoid receptor-mediated repression. |
2008 |
Mol. Cell. Endocrinol. |
pmid:18583028
|
Tshuikina M et al. |
Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. |
2008 |
Exp. Hematol. |
pmid:18922617
|
Biacsi R et al. |
SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. |
2008 |
PLoS Genet. |
pmid:18369442
|
Hishikawa K and Fujita T |
[Kidney regeneration update]. |
2008 |
Nippon Rinsho |
pmid:18464514
|
Wu X et al. |
Trichostatin A improved epigenetic modifications of transfected cells but did not improve subsequent cloned embryo development. |
2008 |
Anim. Biotechnol. |
pmid:18855246
|
Lindström TM et al. |
Histone deacetylase inhibitors exert time-dependent effects on nuclear factor-kappaB but consistently suppress the expression of proinflammatory genes in human myometrial cells. |
2008 |
Mol. Pharmacol. |
pmid:18375836
|
Kato A et al. |
Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. |
2008 |
Exp. Cell Res. |
pmid:18588874
|
Li J et al. |
High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos. |
2008 |
Theriogenology |
pmid:18573521
|
Xu ZM et al. |
The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage. |
2008 |
BMB Rep |
pmid:18377727
|
Chen CJ et al. |
Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18590721
|
Karantzali E et al. |
Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis. |
2008 |
Genome Biol. |
pmid:18394158
|
Marengo E et al. |
Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. |
2008 |
J. Proteome Res. |
pmid:18543959
|
Ree AH et al. |
HDAC2 deficiency and histone acetylation. |
2008 |
Nat. Genet. |
pmid:18583969
|
Galiová G et al. |
Chromatin changes induced by lamin A/C deficiency and the histone deacetylase inhibitor trichostatin A. |
2008 |
Eur. J. Cell Biol. |
pmid:18396346
|
Zhu X et al. |
Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18544619
|
Liu Y et al. |
Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. |
2008 |
Cancer Invest. |
pmid:18584348
|
Gaviraghi M et al. |
Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene. |
2008 |
BMC Mol. Biol. |
pmid:18549468
|
Geli J et al. |
Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. |
2008 |
Int. J. Cancer |
pmid:18452173
|
Nakao Y et al. |
Evaluation of antiangiogenic activity of azumamides by the in vitro vascular organization model using mouse induced pluripotent stem (iPS) cells. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18397826
|
Mühlethaler-Mottet A et al. |
Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells. |
2008 |
Mol. Cancer |
pmid:18549473
|
Chen PC et al. |
Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group. |
2008 |
Bioorg. Med. Chem. |
pmid:18397827
|
Kim B et al. |
Clinically relevant concentrations of valproic acid modulate melatonin MT(1) receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18550052
|
Yan C et al. |
Comparative molecular dynamics simulations of histone deacetylase-like protein: binding modes and free energy analysis to hydroxamic acid inhibitors. |
2008 |
Proteins |
pmid:18398905
|
Tavera-Mendoza LE et al. |
Incorporation of histone deacetylase inhibition into the structure of a nuclear receptor agonist. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18550844
|
Lee TB et al. |
Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy. |
2008 |
BMC Gastroenterol |
pmid:18673531
|
Xiang N et al. |
Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. |
2008 |
Carcinogenesis |
pmid:18676679
|
Northrop JK et al. |
Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells. |
2008 |
J. Immunol. |
pmid:18606637
|
Schmeck B et al. |
Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression. |
2008 |
J. Immunol. |
pmid:18606645
|
Pluemsampant S et al. |
Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. |
2008 |
Int. J. Cancer |
pmid:17935135
|
Zou XM et al. |
Gastric cancer cell lines induced by trichostatin A. |
2008 |
World J. Gastroenterol. |
pmid:18720545
|
Nishino N et al. |
Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides. |
2008 |
Bioorg. Med. Chem. |
pmid:17900911
|
Duan H et al. |
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
2008 |
Oncogene |
pmid:18695675
|
Ding X et al. |
Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. |
2008 |
Theriogenology |
pmid:18556056
|
Jia J and Chen J |
Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death. |
2008 |
Pharmazie |
pmid:18557424
|
Su RC et al. |
Epigenetic regulation of established human type 1 versus type 2 cytokine responses. |
2008 |
J. Allergy Clin. Immunol. |
pmid:17980413
|
Narver HL et al. |
Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition. |
2008 |
Ann. Neurol. |
pmid:18661558
|
Yu J et al. |
Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. |
2008 |
Hepatology |
pmid:18666234
|
Iacobazzi V et al. |
Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18706393
|
Falk M et al. |
Chromatin structure influences the sensitivity of DNA to gamma-radiation. |
2008 |
Biochim. Biophys. Acta |
pmid:18706456
|
Zhang XH et al. |
Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer. |
2008 |
Cancer Biol. Ther. |
pmid:18708766
|
Yang YN et al. |
[Effects of trichostatin A and paclitaxel on apoptosis and mitochondrial membrane potential of human endometrial carcinoma Ark2 cells]. |
2008 |
Ai Zheng |
pmid:18710614
|
Obrdlik A et al. |
The histone acetyltransferase PCAF associates with actin and hnRNP U for RNA polymerase II transcription. |
2008 |
Mol. Cell. Biol. |
pmid:18710935
|
Carlisi D et al. |
Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. |
2008 |
Int. J. Oncol. |
pmid:18097557
|
Seo JS et al. |
Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A. |
2008 |
Oncol. Rep. |
pmid:18097580
|
Yeh JR et al. |
AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. |
2008 |
Development |
pmid:18156164
|
Yoshioka H et al. |
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
2008 |
J. Biol. Chem. |
pmid:18801729
|
Jin B et al. |
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. |
2008 |
Hum. Mol. Genet. |
pmid:18029387
|
Han JQ et al. |
[Effects of trichostatin A on the interaction between HBx and histone deacetylase protein 1]. |
2008 |
Zhonghua Gan Zang Bing Za Zhi |
pmid:18822204
|
Lee EJ et al. |
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
2008 |
Int. J. Oncol. |
pmid:18813790
|
Van Wagoner DR and Nattel S |
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18817781
|
Pellicciotta I et al. |
Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition. |
2008 |
Cancer Res. |
pmid:18829567
|
Hitchler MJ et al. |
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells. |
2008 |
Free Radic. Biol. Med. |
pmid:18845242
|