Dowling DP et al. |
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. |
2008 |
Biochemistry |
pmid:19053282
|
Ishii T et al. |
[Epigenetic regulation in alcohol-related brain damage]. |
2008 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
pmid:19068777
|
Zhu K et al. |
Telomerase expression and cell proliferation in ovarian cancer cells induced by histone deacetylase inhibitors. |
2008 |
Arch. Gynecol. Obstet. |
pmid:17680259
|
Meng CF et al. |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP]. |
2008 |
Ai Zheng |
pmid:19079988
|
Usami M et al. |
Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. |
2008 |
Nutr Res |
pmid:19083427
|
Krämer OH et al. |
Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis. |
2008 |
Oncogene |
pmid:17653085
|
Lim HG et al. |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. |
2008 |
Mol. Ther. |
pmid:18227841
|
Ruau D et al. |
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. |
2008 |
Stem Cells |
pmid:18203677
|
Serrano E et al. |
Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. |
2008 |
Leuk. Res. |
pmid:18206229
|
Hamner JB et al. |
The efficacy of combination therapy using adeno-associated virus--interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma. |
2008 |
J. Pediatr. Surg. |
pmid:18206478
|
Duhamel M et al. |
Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. |
2008 |
FEBS Lett. |
pmid:18206652
|
Campanero MR et al. |
The histone deacetylase inhibitor trichostatin A induces GADD45 gamma expression via Oct and NF-Y binding sites. |
2008 |
Oncogene |
pmid:17724474
|
Kikuno N et al. |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. |
2008 |
Int. J. Cancer |
pmid:18431742
|
Zhang HJ et al. |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. |
2008 |
Placenta |
pmid:18440631
|
Meja KK et al. |
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. |
2008 |
Am. J. Respir. Cell Mol. Biol. |
pmid:18421014
|
Sebastián C et al. |
Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells. |
2008 |
J. Immunol. |
pmid:18424709
|
Biacsi R et al. |
SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. |
2008 |
PLoS Genet. |
pmid:18369442
|
Lindström TM et al. |
Histone deacetylase inhibitors exert time-dependent effects on nuclear factor-kappaB but consistently suppress the expression of proinflammatory genes in human myometrial cells. |
2008 |
Mol. Pharmacol. |
pmid:18375836
|
Kato A et al. |
Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. |
2008 |
Exp. Cell Res. |
pmid:18588874
|
Chen CJ et al. |
Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18590721
|
Marengo E et al. |
Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. |
2008 |
J. Proteome Res. |
pmid:18543959
|
Zhu X et al. |
Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18544619
|
Gaviraghi M et al. |
Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene. |
2008 |
BMC Mol. Biol. |
pmid:18549468
|
Pluemsampant S et al. |
Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. |
2008 |
Int. J. Cancer |
pmid:17935135
|
Nishino N et al. |
Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides. |
2008 |
Bioorg. Med. Chem. |
pmid:17900911
|
Duan H et al. |
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
2008 |
Oncogene |
pmid:18695675
|
Ding X et al. |
Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. |
2008 |
Theriogenology |
pmid:18556056
|
Jia J and Chen J |
Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death. |
2008 |
Pharmazie |
pmid:18557424
|
Narver HL et al. |
Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition. |
2008 |
Ann. Neurol. |
pmid:18661558
|
Yoshioka H et al. |
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
2008 |
J. Biol. Chem. |
pmid:18801729
|
Han JQ et al. |
[Effects of trichostatin A on the interaction between HBx and histone deacetylase protein 1]. |
2008 |
Zhonghua Gan Zang Bing Za Zhi |
pmid:18822204
|
Pellicciotta I et al. |
Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition. |
2008 |
Cancer Res. |
pmid:18829567
|
Cheli Y et al. |
Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2. |
2007 Sep-Oct |
Biochim. Biophys. Acta |
pmid:17669516
|
Yasuda K et al. |
ERas oncogene expression and epigenetic regulation by histone acetylation in human cancer cells. |
2007 Nov-Dec |
Anticancer Res. |
pmid:18225573
|
Kuwajima A et al. |
The histone deacetylase inhibitor butyrate inhibits melanoma cell invasion of Matrigel. |
2007 Nov-Dec |
Anticancer Res. |
pmid:18225587
|
Hosseinkhani M et al. |
Trichostatin A induces myocardial differentiation of monkey ES cells. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17368572
|
Kim HJ et al. |
Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17371805
|
Kitamura H et al. |
Down-regulation of HLA class I antigens in prostate cancer tissues and up-regulation by histone deacetylase inhibition. |
2007 |
J. Urol. |
pmid:17574613
|
Vecsey CG et al. |
Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. |
2007 |
J. Neurosci. |
pmid:17553985
|
Pinnoji RC et al. |
Repressor element-1 silencing transcription factor/neuronal restrictive silencer factor (REST/NRSF) can regulate HSV-1 immediate-early transcription via histone modification. |
2007 |
Virol. J. |
pmid:17555596
|
Kishigami S et al. |
Successful mouse cloning of an outbred strain by trichostatin A treatment after somatic nuclear transfer. |
2007 |
J. Reprod. Dev. |
pmid:17077581
|
Khan Z et al. |
HDAC inhibition amplifies gap junction communication in neural progenitors: potential for cell-mediated enzyme prodrug therapy. |
2007 |
Exp. Cell Res. |
pmid:17555745
|
Donadelli M et al. |
Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine. |
2007 |
Biochim. Biophys. Acta |
pmid:17555830
|
Cantor JP et al. |
Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. |
2007 |
Int. J. Cancer |
pmid:17019711
|
Cecconi D et al. |
Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A. |
2007 |
Proteomics |
pmid:17443844
|
Higashi T et al. |
Histone H2A mobility is regulated by its tails and acetylation of core histone tails. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17445770
|
Hellebrekers DM et al. |
Identification of epigenetically silenced genes in tumor endothelial cells. |
2007 |
Cancer Res. |
pmid:17483324
|
Yi T et al. |
Trichostatin A-mediated upregulation of p21(WAF1) contributes to osteoclast apoptosis. |
2007 |
Exp. Mol. Med. |
pmid:17464183
|
Wong CM et al. |
Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma. |
2007 |
Hepatology |
pmid:17464989
|
Chen Y et al. |
Homeobox gene HOP has a potential tumor suppressive activity in human lung cancer. |
2007 |
Int. J. Cancer |
pmid:17417779
|
Liu T et al. |
Design and synthesis of a potent histone deacetylase inhibitor. |
2007 |
J. Med. Chem. |
pmid:17419603
|
Hwang CK et al. |
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. |
2007 |
Mol. Cell. Biol. |
pmid:17452465
|
Piotrowska H and Jagodzinski PP |
Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines. |
2007 |
Biomed. Pharmacother. |
pmid:17498915
|
Berg T et al. |
Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines. |
2007 |
Leuk. Res. |
pmid:17056112
|
Iliopoulos D et al. |
Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention. |
2007 |
Ann. Rheum. Dis. |
pmid:17502362
|
Sato N et al. |
RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line. |
2007 |
Int. J. Cancer |
pmid:17096327
|
Vikhanskaya F et al. |
Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53. |
2007 |
Nucleic Acids Res. |
pmid:17344317
|
Zhang R et al. |
HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells. |
2007 |
Mol. Cell. Biol. |
pmid:17101789
|
Li YL et al. |
[Impact of trichostatin A on gastric carcinoma cell line SGC-7901]. |
2007 |
Zhonghua Wei Chang Wai Ke Za Zhi |
pmid:17659468
|
Wu Y et al. |
The zinc finger repressor, ZBP-89, recruits histone deacetylase 1 to repress vimentin gene expression. |
2007 |
Genes Cells |
pmid:17663720
|
Schneider G et al. |
HDAC3 is linked to cell cycle machinery in MiaPaCa2 cells by regulating transcription of skp2. |
2007 |
Cell Prolif. |
pmid:17635519
|
Bode KA et al. |
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. |
2007 |
Immunology |
pmid:17635610
|
Imai N et al. |
Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury. |
2007 |
Stem Cells |
pmid:17641247
|
Dai B and Rasmussen TP |
Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells. |
2007 |
Stem Cells |
pmid:17641388
|
Kaida D et al. |
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. |
2007 |
Nat. Chem. Biol. |
pmid:17643111
|
Kotake Y et al. |
Splicing factor SF3b as a target of the antitumor natural product pladienolide. |
2007 |
Nat. Chem. Biol. |
pmid:17643112
|
Kang JH et al. |
Inhibition of trichostatin A-induced antiangiogenesis by small-interfering RNA for thrombospondin-1. |
2007 |
Exp. Mol. Med. |
pmid:17603295
|
Oyama T et al. |
Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo. |
2007 |
J. Cell Biol. |
pmid:17261849
|
Zhang L et al. |
Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18024584
|
Park JJ et al. |
Functional interaction of the human cytomegalovirus IE2 protein with histone deacetylase 2 in infected human fibroblasts. |
2007 |
J. Gen. Virol. |
pmid:18024889
|
Moiseeva EP et al. |
Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. |
2007 |
Mol. Cancer Ther. |
pmid:18025290
|
Brest P et al. |
Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET. |
2007 |
Cancer Res. |
pmid:18056459
|
Sourlingas TG et al. |
Effect of the histone deacetylase inhibitor trichostatin a in human peripheral blood lymphocytes as a function of donor age. |
2007 |
Ann. N. Y. Acad. Sci. |
pmid:18056955
|
Sekhavat A et al. |
Competitive inhibition of histone deacetylase activity by trichostatin A and butyrate. |
2007 |
Biochem. Cell Biol. |
pmid:18059533
|
Mazzarelli P et al. |
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation? |
2007 |
Cancer Biol. Ther. |
pmid:18253084
|
Lee EL et al. |
Impaired activity of volume-sensitive Cl- channel is involved in cisplatin resistance of cancer cells. |
2007 |
J. Cell. Physiol. |
pmid:17186499
|
Koh E et al. |
Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors. |
2007 |
Cancer Lett. |
pmid:17189669
|
Feng W et al. |
Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer. |
2007 |
Int. J. Cancer |
pmid:17230502
|
Wu ZQ et al. |
Histone deacetylase inhibitor trichostatin A induced caspase-independent apoptosis in human gastric cancer cell. |
2007 |
Chin. Med. J. |
pmid:18167185
|
Karam JA et al. |
The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy. |
2007 |
Int. J. Cancer |
pmid:17230511
|
Ghosh AK et al. |
Trichostatin A blocks TGF-beta-induced collagen gene expression in skin fibroblasts: involvement of Sp1. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17234156
|
Shimazu T et al. |
Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing. |
2007 |
J. Biol. Chem. |
pmid:17172643
|
Januchowski R and Jagodzinski PP |
Trichostatin A down-regulates ZAP-70, LAT and SLP-76 content in Jurkat T cells. |
2007 |
Int. Immunopharmacol. |
pmid:17178387
|
Cras A et al. |
Epigenetic patterns of the retinoic acid receptor beta2 promoter in retinoic acid-resistant thyroid cancer cells. |
2007 |
Oncogene |
pmid:17213810
|
Karagiannis TC et al. |
Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments. |
2007 |
Oncogene |
pmid:17213813
|
Zhou X et al. |
The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma. |
2007 |
Cancer Genet. Cytogenet. |
pmid:17693185
|
Wang F et al. |
Dynamic reprogramming of histone acetylation and methylation in the first cell cycle of cloned mouse embryos. |
2007 |
Biol. Reprod. |
pmid:17823087
|
De los Santos M et al. |
Combined effects of retinoic acid and histone deacetylase inhibitors on human neuroblastoma SH-SY5Y cells. |
2007 |
Mol. Cancer Ther. |
pmid:17431121
|
Qi J et al. |
[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. |
2007 |
Zhonghua Zhong Liu Za Zhi |
pmid:18396643
|
Yang H et al. |
Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent. |
2007 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:16973938
|
Li T and Chiang JY |
A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene. |
2007 |
Gastroenterology |
pmid:17920062
|
Tao R et al. |
Deacetylase inhibition promotes the generation and function of regulatory T cells. |
2007 |
Nat. Med. |
pmid:17922010
|
Qi J et al. |
[The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. |
2007 |
Zhonghua Yi Xue Za Zhi |
pmid:17923031
|
Pulukuri SM et al. |
Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator. |
2007 |
J. Biol. Chem. |
pmid:17923479
|
Stapnes C et al. |
Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in susceptibility to histone deacetylase inhibitors. |
2007 |
Int. J. Oncol. |
pmid:17982680
|
Honda H et al. |
Regulation of the CLDN3 gene in ovarian cancer cells. |
2007 |
Cancer Biol. Ther. |
pmid:17986852
|
Renthal W et al. |
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. |
2007 |
Neuron |
pmid:17988634
|
Carén H et al. |
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours. |
2007 |
Br. J. Cancer |
pmid:17940511
|
Dompierre JP et al. |
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation. |
2007 |
J. Neurosci. |
pmid:17392473
|
Hashii M et al. |
Up-regulation of ras-GAP genes is reversed by a MEK inhibitor and doxorubicin in v-Ki-ras-transformed NIH/3T3 fibroblasts. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17367762
|