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Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines. |
2004 |
World J. Gastroenterol. |
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Myzak MC et al. |
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. |
2004 |
Cancer Res. |
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Facchetti F et al. |
Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors. |
2004 |
Apoptosis |
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Roh MS et al. |
Mechanism of histone deacetylase inhibitor Trichostatin A induced apoptosis in human osteosarcoma cells. |
2004 |
Apoptosis |
pmid:15314286
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Schultz BE et al. |
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. |
2004 |
Biochemistry |
pmid:15323567
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Chiba T et al. |
Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells. |
2004 |
J. Hepatol. |
pmid:15336447
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Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. |
2004 |
J. Biol. Chem. |
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Cosio BG et al. |
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. |
2004 |
J. Exp. Med. |
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Tao D et al. |
Trichostatin A extends the lifespan of Drosophila melanogaster by elevating hsp22 expression. |
2004 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:15346199
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Korkmaz CG et al. |
Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants. |
2004 |
J. Endocrinol. |
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Tang XX et al. |
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma. |
2004 |
Clin. Cancer Res. |
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Yokota T et al. |
Trichostatin A activates p18INK4c gene: differential activation and cooperation with p19INK4d gene. |
2004 |
FEBS Lett. |
pmid:15358560
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Boehrer S et al. |
In the erythroleukemic cell line HEL Prostate-apoptosis-response-gene-4 (par-4) fails to down-regulate Bcl-2 and to promote apoptosis. |
2004 |
Leuk. Lymphoma |
pmid:15359646
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Vaghefi H and Neet KE |
Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation. |
2004 |
Oncogene |
pmid:15361854
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Moore PS et al. |
Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cells. |
2004 |
Biochim. Biophys. Acta |
pmid:15363630
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Laeng P et al. |
The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells. |
2004 |
J. Neurochem. |
pmid:15379904
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Kim MK and Carroll WL |
Autoregulation of the N-myc gene is operative in neuroblastoma and involves histone deacetylase 2. |
2004 |
Cancer |
pmid:15382088
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Davis FJ et al. |
Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility. |
2005 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:15388503
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Chen JS and Faller DV |
Histone deacetylase inhibition-mediated post-translational elevation of p27KIP1 protein levels is required for G1 arrest in fibroblasts. |
2005 |
J. Cell. Physiol. |
pmid:15389542
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Frønsdal K and Saatcioglu F |
Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells. |
2005 |
Prostate |
pmid:15389787
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Fan X et al. |
Regulation of RANKL promoter activity is associated with histone remodeling in murine bone stromal cells. |
2004 |
J. Cell. Biochem. |
pmid:15389882
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Zelko IN and Folz RJ |
Sp1 and Sp3 transcription factors mediate trichostatin A-induced and basal expression of extracellular superoxide dismutase. |
2004 |
Free Radic. Biol. Med. |
pmid:15451065
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Chiba T et al. |
Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells. |
2004 |
Oncology |
pmid:15452378
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Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15454224
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p73 competes with co-activators and recruits histone deacetylase to NF-Y in the repression of PDGF beta-receptor. |
2004 |
J. Cell. Sci. |
pmid:15454570
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Subtype selective substrates for histone deacetylases. |
2004 |
J. Med. Chem. |
pmid:15456267
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Histone H4 hyperacetylation precludes histone H4 lysine 20 trimethylation. |
2004 |
J. Biol. Chem. |
pmid:15456746
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Jori FP et al. |
RB and RB2/p130 genes demonstrate both specific and overlapping functions during the early steps of in vitro neural differentiation of marrow stromal stem cells. |
2005 |
Cell Death Differ. |
pmid:15459751
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Potent stimulation of gene expression by histone deacetylase inhibitors on transiently transfected DNA. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15465025
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Gene expression analysis in human gastric cancer cell line treated with trichostatin A and S-adenosyl-L-homocysteine using cDNA microarray. |
2004 |
Biol. Pharm. Bull. |
pmid:15467184
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Molecular profiling of embryonal carcinoma cells following retinoic acid or histone deacetylase inhibitor treatment. |
2004 |
Cancer Biol. Ther. |
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Vaquero A et al. |
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. |
2004 |
Mol. Cell |
pmid:15469825
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Ladd PD et al. |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. |
2004 |
Gene |
pmid:15474314
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Li H and Wu X |
Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474507
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Spenger A et al. |
Influence of promoter choice and trichostatin A treatment on expression of baculovirus delivered genes in mammalian cells. |
2004 |
Protein Expr. Purif. |
pmid:15477077
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Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. |
2004 |
Circ. Res. |
pmid:15486319
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Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. |
2004 |
Cancer Cell |
pmid:15488759
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Alikhani-Koopaei R et al. |
Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. |
2004 |
J. Clin. Invest. |
pmid:15489962
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Trichostatin A induces apoptosis of p815 mastocytoma cells in histone acetylation- and mitochondria-dependent fashion. |
2004 |
Int. J. Oncol. |
pmid:15492835
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Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression. |
2004 |
Biochem. Soc. Trans. |
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Sumoylation of internally initiated Sp3 isoforms regulates transcriptional repression via a Trichostatin A-insensitive mechanism. |
2005 |
Cell. Signal. |
pmid:15494207
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Histone deacetylase inhibitors upregulate plakoglobin expression in bladder carcinoma cells and display antineoplastic activity in vitro and in vivo. |
2005 |
Int. J. Cancer |
pmid:15499627
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Major chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes is dispensable for global transcriptional silencing but required for centromeric heterochromatin function. |
2004 |
Dev. Biol. |
pmid:15501230
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The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors. |
2004 |
J. Biol. Chem. |
pmid:15507435
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Chang S and Pikaard CS |
Transcript profiling in Arabidopsis reveals complex responses to global inhibition of DNA methylation and histone deacetylation. |
2005 |
J. Biol. Chem. |
pmid:15516340
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Wang S and Zhu J |
The hTERT gene is embedded in a nuclease-resistant chromatin domain. |
2004 |
J. Biol. Chem. |
pmid:15516693
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El-Khoury V et al. |
Effects of the histone deacetylase inhibitor trichostatin A on nuclear texture and c-jun gene expression in drug-sensitive and drug-resistant human H69 lung carcinoma cells. |
2004 |
Cytometry A |
pmid:15517561
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Kawano T et al. |
Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect. |
2004 Sep-Oct |
Anticancer Res. |
pmid:15517875
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Hammond SM et al. |
Negative regulatory elements are present in the human LMO2 oncogene and may contribute to its expression in leukemia. |
2005 |
Leuk. Res. |
pmid:15541480
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Ramakrishnan G et al. |
Histone acetyltransferases and deacetylase in Entamoeba histolytica. |
2004 |
Mol. Biochem. Parasitol. |
pmid:15555732
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