López-Solache I et al. |
Regulation of uncoupling protein-2 mRNA in L6 myotubules: II: Thyroid hormone amplifies stimulation of uncoupling protein-2 gene by thiazolidinediones and other peroxisome proliferator-activated receptor ligands in L6 myotubules: evidence for a priming effect. |
2002 |
Endocrine |
pmid:12588052
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. |
2002 |
Brain Tumor Pathol |
pmid:12622137
|
Suzuki-Mizushima Y et al. |
Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. |
2002 |
Brain Res. |
pmid:12270499
|
Boutillier AL et al. |
Constitutive repression of E2F1 transcriptional activity through HDAC proteins is essential for neuronal survival. |
2002 |
Ann. N. Y. Acad. Sci. |
pmid:12485907
|
Drewell RA et al. |
Methylation-dependent silencing at the H19 imprinting control region by MeCP2. |
2002 |
Nucleic Acids Res. |
pmid:11861904
|
Murphy JC et al. |
Control of cytomegalovirus lytic gene expression by histone acetylation. |
2002 |
EMBO J. |
pmid:11867539
|
Gregory RI et al. |
Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells. |
2002 |
J. Biol. Chem. |
pmid:11821379
|
Elaut G et al. |
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. |
2002 |
Drug Metab. Dispos. |
pmid:12433798
|
Lim Y et al. |
Trichostatin A-induced detransformation correlates with decreased focal adhesion kinase phosphorylation at tyrosine 861 in ras-transformed fibroblasts. |
2002 |
J. Biol. Chem. |
pmid:11821402
|
Yáñez RJ and Porter AC |
A chromosomal position effect on gene targeting in human cells. |
2002 |
Nucleic Acids Res. |
pmid:12433992
|
Wilson MA et al. |
The histone deacetylase inhibitor trichostatin A blocks progesterone receptor-mediated transactivation of the mouse mammary tumor virus promoter in vivo. |
2002 |
J. Biol. Chem. |
pmid:11821430
|
Takechi S et al. |
Chicken HDAC2 down-regulates IgM light chain gene promoter activity. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12437980
|
Deroanne CF et al. |
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. |
2002 |
Oncogene |
pmid:11821955
|
Ego T et al. |
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression. |
2002 |
Oncogene |
pmid:12370815
|
Zhang W and Kone BC |
NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: role of histone deacetylases. |
2002 |
Am. J. Physiol. Renal Physiol. |
pmid:12372765
|
Handumrongkul C et al. |
Distinct sets of cellular genes control the expression of transfected, nuclear-localized genes. |
2002 |
Mol. Ther. |
pmid:11829526
|
Ailenberg M and Silverman M |
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12379227
|
Herold C et al. |
The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. |
2002 |
J. Hepatol. |
pmid:11830335
|
Yamashita K et al. |
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. |
2002 |
Cancer Cell |
pmid:12498717
|
Zhou DC et al. |
Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. |
2002 |
Blood |
pmid:11830487
|
Fahrner JA et al. |
Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. |
2002 |
Cancer Res. |
pmid:12499261
|
Valapour M et al. |
Histone deacetylation inhibits IL4 gene expression in T cells. |
2002 |
J. Allergy Clin. Immunol. |
pmid:11842291
|
McBurney MW et al. |
Evidence for repeat-induced gene silencing in cultured Mammalian cells: inactivation of tandem repeats of transfected genes. |
2002 |
Exp. Cell Res. |
pmid:11855851
|
Hou M et al. |
The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells. |
2002 |
Exp. Cell Res. |
pmid:11855854
|
Bordonaro M et al. |
Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. |
2002 |
Int. J. Cancer |
pmid:11774242
|
Kikuchi T et al. |
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. |
2002 |
Int. J. Cancer |
pmid:11774276
|
Rombouts K et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses collagen synthesis and prevents TGF-beta(1)-induced fibrogenesis in skin fibroblasts. |
2002 |
Exp. Cell Res. |
pmid:12169274
|
Waterborg JH and Kapros T |
Kinetic analysis of histone acetylation turnover and Trichostatin A induced hyper- and hypoacetylation in alfalfa. |
2002 |
Biochem. Cell Biol. |
pmid:12123281
|
Mikkelsen IM et al. |
Activation of the gamma-glutamyltransferase promoter 2 in the rat colon carcinoma cell line CC531 by histone deacetylase inhibitors is mediated through the Sp1 binding motif. |
2002 |
Biochem. Pharmacol. |
pmid:12123752
|
Petti MC et al. |
Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies. |
2002 |
Blood |
pmid:12130525
|
Avram D et al. |
COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein. |
2002 |
Biochem. J. |
pmid:12196208
|
Guo Y et al. |
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. |
2002 |
J. Biol. Chem. |
pmid:12198113
|
Wittich S et al. |
Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. |
2002 |
J. Med. Chem. |
pmid:12109913
|
Toyooka S et al. |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. |
2002 |
Clin. Cancer Res. |
pmid:12114433
|
Chiocca S et al. |
Histone deacetylase 1 inactivation by an adenovirus early gene product. |
2002 |
Curr. Biol. |
pmid:11937030
|
Curradi M et al. |
Molecular mechanisms of gene silencing mediated by DNA methylation. |
2002 |
Mol. Cell. Biol. |
pmid:11940673
|
Koyama N et al. |
Differential effects of histone deacetylase inhibitors on interleukin-18 gene expression in myeloid cells. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11944905
|
Nair RR et al. |
Enhancement of transgene expression by combining glucocorticoids and anti-mitotic agents during transient transfection using DNA-cationic liposomes. |
2002 |
Mol. Ther. |
pmid:11945073
|
Qiu P and Li L |
Histone acetylation and recruitment of serum responsive factor and CREB-binding protein onto SM22 promoter during SM22 gene expression. |
2002 |
Circ. Res. |
pmid:11988486
|
Mai A et al. |
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. |
2002 |
J. Med. Chem. |
pmid:11960489
|
Merezak C et al. |
Inhibition of histone deacetylases induces bovine leukemia virus expression in vitro and in vivo. |
2002 |
J. Virol. |
pmid:11967319
|
Weston AD et al. |
Requirement for RAR-mediated gene repression in skeletal progenitor differentiation. |
2002 |
J. Cell Biol. |
pmid:12105181
|
Toyooka S et al. |
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. |
2002 |
Oncogene |
pmid:12082623
|
Maehara K et al. |
Effects of histone acetylation on transcriptional regulation of manganese superoxide dismutase gene. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12083788
|
Iezzi S et al. |
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032356
|
Nielsen J |
Combinatorial synthesis of natural products. |
2002 |
Curr Opin Chem Biol |
pmid:12023109
|
Bereshchenko OR et al. |
Acetylation inactivates the transcriptional repressor BCL6. |
2002 |
Nat. Genet. |
pmid:12402037
|
Chen Z et al. |
Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells. |
2002 |
Cancer Lett. |
pmid:12406558
|
Gálfi P et al. |
Apoptosis sensitivity is not correlated with sensitivity to proliferation inhibition by the histone deacetylase inhibitors butyrate and TSA. |
2002 |
Cancer Lett. |
pmid:12406559
|
Travers H et al. |
Human CD34+ hematopoietic progenitor cells hyperacetylate core histones in response to sodium butyrate, but not trichostatin A. |
2002 |
Exp. Cell Res. |
pmid:12413881
|
Wilson AJ et al. |
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. |
2002 |
Cancer Res. |
pmid:12414619
|
Choy JS and Kron SJ |
NuA4 subunit Yng2 function in intra-S-phase DNA damage response. |
2002 |
Mol. Cell. Biol. |
pmid:12417725
|
Ghoshal K et al. |
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. |
2002 |
Mol. Cell. Biol. |
pmid:12417732
|
Hauser C et al. |
Activation of the mouse histone deacetylase 1 gene by cooperative histone phosphorylation and acetylation. |
2002 |
Mol. Cell. Biol. |
pmid:12391151
|
Westendorf JJ et al. |
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. |
2002 |
Mol. Cell. Biol. |
pmid:12391164
|
Sourlingas TG et al. |
The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H1(0) synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study. |
2002 Jan-Mar |
Exp. Gerontol. |
pmid:11772521
|
Iwata K et al. |
Trichostatin A, a histone deacetylase inhibitor, down-regulates interleukin-12 transcription in SV-40-transformed lung epithelial cells. |
2002 Jul-Aug |
Cell. Immunol. |
pmid:12470611
|
Noss KR et al. |
Methylation state of the prostate specific membrane antigen (PSMA) CpG island in prostate cancer cell lines. |
2002 May-Jun |
Anticancer Res. |
pmid:12168830
|
Rahman I et al. |
Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. |
2002 May-Jun |
Mol. Cell. Biochem. |
pmid:12162440
|
Lietz M et al. |
RE-1 silencing transcription factor (REST) regulates human synaptophysin gene transcription through an intronic sequence-specific DNA-binding site. |
2003 |
Eur. J. Biochem. |
pmid:12492469
|
Yamashita Y et al. |
Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells. |
2003 |
Int. J. Cancer |
pmid:12494463
|
Parekh-Olmedo H et al. |
The effect of hydroxyurea and trichostatin a on targeted nucleotide exchange in yeast and Mammalian cells. |
2003 |
Ann. N. Y. Acad. Sci. |
pmid:14751821
|
Papeleu P et al. |
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes. |
2003 |
J. Hepatol. |
pmid:12927923
|
Senawong T et al. |
Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression. |
2003 |
J. Biol. Chem. |
pmid:12930829
|
Mulholland NM et al. |
Inhibition of MMTV transcription by HDAC inhibitors occurs independent of changes in chromatin remodeling and increased histone acetylation. |
2003 |
Oncogene |
pmid:12894222
|
Banwell CM et al. |
Antiproliferative signalling by 1,25(OH)2D3 in prostate and breast cancer is suppressed by a mechanism involving histone deacetylation. |
2003 |
Recent Results Cancer Res. |
pmid:12899515
|
Yan Y et al. |
Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure. |
2003 |
Toxicol. Appl. Pharmacol. |
pmid:12902198
|
Augenlicht L et al. |
Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation. |
2003 |
Oncogene |
pmid:12902981
|
Cho B et al. |
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12849980
|
Thomas RM et al. |
Regulation of mouse mammary tumor virus env transcriptional activator initiated mammary tumor virus superantigen transcripts in lymphomas of SJL/J mice: role of Ikaros, demethylation, and chromatin structural change in the transcriptional activation of mammary tumor virus superantigen. |
2003 |
J. Immunol. |
pmid:12496403
|
Xu Y et al. |
SHP-1 sensitizes MCF-7 cells to trichostatin A-induced apoptosis by modulating PI3K-dependent events. |
2003 |
Cell Death Differ. |
pmid:14502244
|
Adam E et al. |
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha. |
2003 |
Mol. Cell. Biol. |
pmid:12917341
|
Donadelli M et al. |
Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells. |
2003 |
Mol. Carcinog. |
pmid:14502645
|
Bartoli A et al. |
Effect of trichostatin a and 5'-azacytidine on transgene reactivation in U937 transduced cells. |
2003 |
Pharmacol. Res. |
pmid:12770523
|
Koeller KM et al. |
Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation. |
2003 |
Chem. Biol. |
pmid:12770822
|
Agoulnik IU et al. |
Repressors of androgen and progesterone receptor action. |
2003 |
J. Biol. Chem. |
pmid:12771131
|
Huang Y et al. |
Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma. |
2003 |
Int. J. Cancer |
pmid:12640681
|
Méndez-Pertuz M et al. |
The thyroid hormone receptor antagonizes CREB-mediated transcription. |
2003 |
EMBO J. |
pmid:12805224
|
Illi B et al. |
Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression. |
2003 |
Circ. Res. |
pmid:12805238
|
Kim HS et al. |
Regulation of the tyrosine hydroxylase gene promoter by histone deacetylase inhibitors. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14651963
|
Coombes MM et al. |
Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation. |
2003 |
Oncogene |
pmid:14654786
|
Marshall S et al. |
Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors: kinetics of cytosolic OGT accumulation and nuclear translocation. |
2003 |
Anal. Biochem. |
pmid:12871726
|
Chan AS et al. |
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. |
2003 |
Oncogene |
pmid:14534543
|
Allison SJ and Milner J |
Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy. |
2003 |
Cancer Res. |
pmid:14583461
|
Mai A et al. |
Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A. |
2003 |
J. Med. Chem. |
pmid:14584932
|
Pace BS et al. |
p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors. |
2003 |
Exp. Hematol. |
pmid:14585374
|
Fukuoka M et al. |
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation. |
2003 |
Int. J. Mol. Med. |
pmid:12964026
|
Vanommeslaeghe K et al. |
Ab initio study of the binding of Trichostatin A (TSA) in the active site of histone deacetylase like protein (HDLP). |
2003 |
Org. Biomol. Chem. |
pmid:12968347
|
Huang H et al. |
[HDAC1 expression and effect of TSA on proliferation and apoptosis of A549 cells]. |
2003 |
Ai Zheng |
pmid:12969522
|
Ohike N et al. |
Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas. |
2003 |
Cancer Lett. |
pmid:12969792
|
Fass DM et al. |
Deacetylase activity is required for cAMP activation of a subset of CREB target genes. |
2003 |
J. Biol. Chem. |
pmid:12939274
|
Zhao C et al. |
A composite motif of the Drosophila morphogenetic protein bicoid critical to transcription control. |
2003 |
J. Biol. Chem. |
pmid:12939280
|
Hinoi T et al. |
Silencing of CDX2 expression in colon cancer via a dominant repression pathway. |
2003 |
J. Biol. Chem. |
pmid:12947088
|
Chambers AE et al. |
Histone acetylation-mediated regulation of genes in leukaemic cells. |
2003 |
Eur. J. Cancer |
pmid:12736119
|
Hoever G et al. |
The mechanism of 3'-azido-2',3'-dideoxythymidine resistance to human lymphoid cells. |
2003 |
Int. J. Mol. Med. |
pmid:12736716
|
Valenta T et al. |
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. |
2003 |
Nucleic Acids Res. |
pmid:12711682
|
Arora T et al. |
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. |
2003 |
J. Biol. Chem. |
pmid:12716907
|
Sonoyama K et al. |
Upregulation of activin A gene by butyrate in human colon cancer cell lines. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12540370
|
Kagoshima M et al. |
Glucocorticoid suppression of nuclear factor-kappa B: a role for histone modifications. |
2003 |
Biochem. Soc. Trans. |
pmid:12546654
|
Bhat RA et al. |
Alteration of GCN5 levels in maize reveals dynamic responses to manipulating histone acetylation. |
2003 |
Plant J. |
pmid:12581304
|