Yang X et al. |
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. |
2009 |
PLoS ONE |
pmid:19340297
|
Slattery EL et al. |
Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle. |
2009 |
J. Assoc. Res. Otolaryngol. |
pmid:19340485
|
Vilar E et al. |
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. |
2009 |
Clin. Cancer Res. |
pmid:19351759
|
Lu SC et al. |
The essential role of Oct-2 in LPS-induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19279235
|
Luo SF et al. |
Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. |
2009 |
Toxicol. Appl. Pharmacol. |
pmid:19281832
|
Giannini G et al. |
N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19285395
|
Ueda JY et al. |
JBIR-17, a novel trichostatin analog from Streptomyces sp. 26634. |
2009 |
J. Antibiot. |
pmid:19300468
|
Noro R et al. |
The anticancer effect of histone deacetylase inhibitors and combination with the cytotoxic agents in lung cancer cells: biological analyses for future clinical application. |
2009 |
J Nippon Med Sch |
pmid:19305113
|
Glenn DJ et al. |
Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2. |
2009 |
Hypertension |
pmid:19139378
|
Deng G et al. |
Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs. |
2009 |
Clin. Cancer Res. |
pmid:19223499
|
Sterthaus O et al. |
Evaluation of in vitro cultured rat oocytes, from different strains, by spindle morphology and maturation-promoting-factor activity combined with nuclear-transfer experiments. |
2009 |
Cloning Stem Cells |
pmid:19751114
|
Wang X et al. |
Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents. |
2009 |
Cancer Res. |
pmid:19752087
|
Hirata H et al. |
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. |
2009 |
Clin. Cancer Res. |
pmid:19755393
|
Chiou SK and Hoa N |
Up-regulation of GADD45alpha expression by NSAIDs leads to apoptotic and necrotic colon cancer cell deaths. |
2009 |
Apoptosis |
pmid:19757064
|
Vire B et al. |
Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions. |
2009 |
PLoS ONE |
pmid:19759901
|
Lugrin J et al. |
Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation. |
2009 |
Biochim. Biophys. Acta |
pmid:19747950
|
Cervera RP et al. |
Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryos. |
2009 |
Theriogenology |
pmid:19765811
|
Diplas AI et al. |
Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. |
2009 |
Nucleic Acids Res. |
pmid:19767614
|
Ma XX et al. |
Histone deacetylase inhibitor trichostatin A modulates cell cycles in A2780 human ovarian cancer cell lines. |
2009 |
Eur. J. Gynaecol. Oncol. |
pmid:19697617
|
Izawa M et al. |
Inhibition of histone deacetylase causes reduction of appressorium formation in the rice blast fungus Magnaporthe oryzae. |
2009 |
J. Gen. Appl. Microbiol. |
pmid:20118613
|
Guo W et al. |
Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition. |
2009 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:19700647
|
Yamanaka K et al. |
Acetylation level of histone H3 in early embryonic stages affects subsequent development of miniature pig somatic cell nuclear transfer embryos. |
2009 |
J. Reprod. Dev. |
pmid:19700928
|
McCulloch MW et al. |
Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives. |
2009 |
Bioorg. Med. Chem. |
pmid:19022675
|
Gao J et al. |
Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site. |
2009 |
Glia |
pmid:19062177
|
Noh EJ et al. |
An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19038231
|
Kong X et al. |
HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells. |
2009 |
J. Mol. Cell. Cardiol. |
pmid:19041327
|
Rossi M et al. |
Caspase cleavage of Itch in chronic lymphocytic leukemia cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19073138
|
Hostetter CL et al. |
Timing is everything: order of administration of 5-aza 2' deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity. |
2009 |
Cancer Lett. |
pmid:19013015
|
Heo H et al. |
Suppression of caspase-11 expression by histone deacetylase inhibitors. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19013432
|
Chen Y et al. |
3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment. |
2009 |
Eur J Med Chem |
pmid:19136179
|
Cowell RM et al. |
Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19118529
|
Wiesen JL and Tomasi TB |
Dicer is regulated by cellular stresses and interferons. |
2009 |
Mol. Immunol. |
pmid:19118902
|
Togi S et al. |
HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19121623
|
Dje N'Guessan P et al. |
Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:19122173
|
Yamada N et al. |
Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. |
2009 |
Br. J. Cancer |
pmid:19127263
|
Kishigami S and Wakayama T |
Somatic cell nuclear transfer in the mouse. |
2009 |
Methods Mol. Biol. |
pmid:19085136
|
Sibinga NE |
Stable protein, unstable plaque? |
2009 |
J. Mol. Cell. Cardiol. |
pmid:19101562
|
Niu F et al. |
Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-kappaB. |
2009 |
Brain Res. Bull. |
pmid:19103266
|
Santiago A et al. |
Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions. |
2009 |
Cell Cycle |
pmid:19106612
|
Kekatpure VD et al. |
HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. |
2009 |
J. Biol. Chem. |
pmid:19158084
|
Riester D et al. |
Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19457659
|
Kim HN et al. |
Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. |
2009 |
Eur. J. Pharmacol. |
pmid:19766111
|
Woodfield GW et al. |
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. |
2009 |
Clin. Cancer Res. |
pmid:19458056
|
Hauswald S et al. |
Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes. |
2009 |
Clin. Cancer Res. |
pmid:19458058
|
Arce L et al. |
Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression. |
2009 |
BMC Cancer |
pmid:19460168
|
Petr J et al. |
Histone deacetylase inhibition improves meiotic competence but not developmental competence in growing pig oocytes. |
2009 |
Zygote |
pmid:19460191
|
Ku WC et al. |
Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. |
2009 |
Mol. Cell Proteomics |
pmid:19505873
|
Kondo T et al. |
Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas. |
2009 |
Lab. Invest. |
pmid:19506552
|
Bonetto A et al. |
Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. |
2009 |
Curr Cancer Drug Targets |
pmid:19508174
|
Chang J et al. |
The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons. |
2009 |
J. Cell. Sci. |
pmid:19509051
|
Nakajima S et al. |
Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231. |
2009 |
Oncol. Rep. |
pmid:19513516
|
Takaya T et al. |
MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells. |
2009 |
Circ. J. |
pmid:19521018
|
Sugimura S et al. |
Interspecies somatic cell nucleus transfer with porcine oocytes as recipients: A novel bioassay system for assessing the competence of canine somatic cells to develop into embryos. |
2009 |
Theriogenology |
pmid:19524287
|
Gregorie CJ et al. |
Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence. |
2009 |
J. Reprod. Immunol. |
pmid:19493573
|
Araki H et al. |
Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues. |
2009 |
Exp. Hematol. |
pmid:19501128
|
Pulukuri SM et al. |
Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer. |
2009 |
Oncogene |
pmid:19503093
|
Tian F et al. |
Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1. |
2009 |
J. Neurochem. |
pmid:19476549
|
Soriano FX et al. |
Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2. |
2009 |
Epigenetics |
pmid:19430206
|
Thiel A et al. |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. |
2009 |
Clin. Cancer Res. |
pmid:19584167
|
Rahim R and Strobl JS |
Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells. |
2009 |
Anticancer Drugs |
pmid:19584707
|
Nadasi E et al. |
Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. |
2009 |
Anticancer Res. |
pmid:19528494
|
Giustiniani J et al. |
Basal endothelial nitric oxide synthase (eNOS) phosphorylation on Ser(1177) occurs in a stable microtubule- and tubulin acetylation-dependent manner. |
2009 |
Exp. Cell Res. |
pmid:19632222
|
Chandrasekaran S et al. |
Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes. |
2009 |
FASEB J. |
pmid:19638401
|
Imesch P et al. |
MLH1 protects from resistance acquisition by the histone deacetylase inhibitor trichostatin A in colon tumor cells. |
2009 |
Int. J. Oncol. |
pmid:19639184
|
Ma GD et al. |
[Role of histone deacetylase in inhibiting invasion of human gastric carcinoma cell line SGC-7901 by PPARgamma-mediated pathway]. |
2009 |
Ai Zheng |
pmid:19624894
|
Hong Z et al. |
Microarray study of mechanism of trichostatin a inducing apoptosis of Molt-4 cells. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:19662360
|
Dagtas AS et al. |
Histone deacetylase inhibitor uses p21(Cip1) to maintain anergy in CD4+ T cells. |
2009 |
Int. Immunopharmacol. |
pmid:19664724
|
Carambula SF et al. |
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19665989
|
Fujii K et al. |
Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells. |
2009 |
Cell Prolif. |
pmid:19614672
|
Pang M et al. |
Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. |
2009 |
Am. J. Physiol. Renal Physiol. |
pmid:19640900
|
Monks A et al. |
Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts. |
2009 |
Anticancer Drugs |
pmid:19606018
|
Hemmatazad H et al. |
Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis. |
2009 |
Arthritis Rheum. |
pmid:19404935
|
Yeh JR et al. |
Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. |
2009 |
Nat. Chem. Biol. |
pmid:19172146
|
Shao GB et al. |
Effect of trychostatin A treatment on gene expression in cloned mouse embryos. |
2009 |
Theriogenology |
pmid:19246084
|
Cunneen TS et al. |
In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. |
2009 |
Arch. Ophthalmol. |
pmid:19365017
|
Charrier C et al. |
Synthesis and modeling of new benzofuranone histone deacetylase inhibitors that stimulate tumor suppressor gene expression. |
2009 |
J. Med. Chem. |
pmid:19385600
|
Yap OW et al. |
Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. |
2009 |
Anticancer Res. |
pmid:19331143
|
Åuczak MW and JagodziÅ„ski PP |
Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
pmid:18602794
|
Sun F et al. |
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. |
2009 |
Mol. Cancer Ther. |
pmid:19934278
|
Koh HS et al. |
Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells. |
2009 |
Mol. Cells |
pmid:19937140
|
Federman N et al. |
Histone acetylation is recruited in consolidation as a molecular feature of stronger memories. |
2009 |
Learn. Mem. |
pmid:19794185
|
Auer D et al. |
Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
pmid:18618240
|
Ai J et al. |
HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer. |
2009 |
Mol. Endocrinol. |
pmid:19855091
|
Codd R et al. |
Zn(II)-dependent histone deacetylase inhibitors: suberoylanilide hydroxamic acid and trichostatin A. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:18725319
|
Peng DF et al. |
DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. |
2009 |
Gut |
pmid:18664505
|
Gavin DP et al. |
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population. |
2009 |
J Psychiatr Res |
pmid:19187942
|
Sasaki K et al. |
Real-time imaging of histone H4 hyperacetylation in living cells. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805290
|
Gibbs A et al. |
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805354
|
Popova EY et al. |
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. |
2009 |
Chromosome Res. |
pmid:19172406
|
Tsuji Y et al. |
The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine. |
2009 |
Zygote |
pmid:19175955
|
Lee JH et al. |
Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. |
2009 |
Mol. Cancer Res. |
pmid:19808903
|
Bao Y et al. |
Identification of trichostatin A as a novel transcriptional up-regulator of scavenger receptor BI both in HepG2 and RAW 264.7 cells. |
2009 |
Atherosclerosis |
pmid:18930459
|
Chen CZ et al. |
The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well. |
2009 |
Br. J. Pharmacol. |
pmid:19785660
|
Bonazzi VF et al. |
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. |
2009 |
Genes Chromosomes Cancer |
pmid:18803327
|
Meng CF et al. |
Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. |
2009 |
Oncol. Rep. |
pmid:19787243
|
Iljin K et al. |
High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth. |
2009 |
Clin. Cancer Res. |
pmid:19789329
|
Fraczek J et al. |
Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors. |
2009 |
Invest New Drugs |
pmid:18825314
|
Hoebeeck J et al. |
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. |
2009 |
Cancer Lett. |
pmid:18819746
|
Demircan B et al. |
Comparative epigenomics of human and mouse mammary tumors. |
2009 |
Genes Chromosomes Cancer |
pmid:18836996
|
Lee SH et al. |
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. |
2009 |
Oncogene |
pmid:18850007
|