| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
| Medulloblastoma | D008527 | 22 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Lymphoma, Follicular | D008224 | 3 associated lipids |
| Lymphatic Metastasis | D008207 | 10 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lupus Vulgaris | D008177 | 1 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Chromosome Inversion | D007446 | 1 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Immunologic Deficiency Syndromes | D007153 | 8 associated lipids |
| Hypesthesia | D006987 | 1 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypersensitivity | D006967 | 22 associated lipids |
trichostatin A
Trichostatin is a lipid of Polyketides (PK) class. Trichostatin is associated with abnormalities such as Dentatorubral-Pallidoluysian Atrophy, PARAGANGLIOMAS 3, abnormal fragmented structure, Disintegration (morphologic abnormality) and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Acetylation, Cell Differentiation process, histone modification, Gene Silencing and Transcriptional Activation. Trichostatin often locates in CD41a, Hematopoietic System, Chromatin Structure, Blood and Endothelium. The associated genes with Trichostatin are SPI1 gene, CELL Gene, Chromatin, CXCR4 gene and DNMT1 gene. The related lipids are Butyrates, Promega, butyrate, Lipopolysaccharides and Steroids. The related experimental models are Knock-out, Mouse Model, Xenograft Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of trichostatin A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with trichostatin A?
trichostatin A is suspected in Infection, Morphologically altered structure, Ureteral obstruction, Photosensitization, Atherosclerosis, Hypertrophic Cardiomyopathy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with trichostatin A
PubChem Associated disorders and diseases
What pathways are associated with trichostatin A
Lipid pathways are not clear in current pathway databases. We organized associated pathways with trichostatin A through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with trichostatin A?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with trichostatin A?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with trichostatin A?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with trichostatin A?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with trichostatin A?
Mouse Model
Mouse Model are used in the study 'Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer.' (Majid S et al., 2010), Mouse Model are used in the study 'Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.' (Fang MZ et al., 2005) and Mouse Model are used in the study 'Histone deacetylase 3 mediates allergic skin inflammation by regulating expression of MCP1 protein.' (Kim Y et al., 2012).
Xenograft Model
Xenograft Model are used in the study 'Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.' (Landreville S et al., 2012), Xenograft Model are used in the study 'Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.' (Moiseeva EP et al., 2007) and Xenograft Model are used in the study 'Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.' (Touma SE et al., 2005).
Cancer Model
Cancer Model are used in the study 'Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice.' (Sanderson L et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with trichostatin A
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mukhopadhyay NK et al. | Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. | 2006 | Ann. Thorac. Surg. | pmid:16488717 |
| Swanson S | Invited commentary. | 2006 | Ann. Thorac. Surg. | pmid:16488718 |
| Song YF et al. | High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. | 2006 | J. Clin. Pathol. | pmid:16489177 |
| Rokhlin OW et al. | Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells. | 2006 | Mol. Cancer Res. | pmid:16513842 |
| Williams SA et al. | NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. | 2006 | EMBO J. | pmid:16319923 |
| Kiefer J et al. | Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. | 2006 | Br. J. Nutr. | pmid:17092367 |
| Kishigami S et al. | Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids. | 2006 | Dev. Biol. | pmid:16325170 |
| Mogal A and Abdulkadir SA | Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes. | 2006 | Mol. Cell. Probes | pmid:16326072 |
| Trapp J et al. | Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. | 2006 | J. Med. Chem. | pmid:17149860 |
| Rebbaa A et al. | The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis. | 2006 | Cell Death Differ. | pmid:16557274 |
| Suuronen T et al. | Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. | 2006 | Neurochem. Int. | pmid:16797784 |
| Krishnan M et al. | Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. | 2006 | FASEB J. | pmid:16246867 |
| Wallace DM et al. | Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. | 2006 | Invest. Ophthalmol. Vis. Sci. | pmid:16799012 |
| Pampalakis G and Sotiropoulou G | Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. | 2006 | Biol. Chem. | pmid:16800739 |
| Wang Y et al. | Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. | 2006 | Arthritis Rheum. | pmid:16802366 |
| Morinobu A et al. | Trichostatin A cooperates with Fas-mediated signal to induce apoptosis in rheumatoid arthritis synovial fibroblasts. | 2006 | J. Rheumatol. | pmid:16755652 |
| Dannenberg LO et al. | Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. | 2006 | Alcohol. Clin. Exp. Res. | pmid:16737450 |
| Cabrero JR et al. | Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. | 2006 | Mol. Biol. Cell | pmid:16738306 |
| Vulcano F et al. | HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers. | 2006 | Exp. Cell Res. | pmid:16739251 |
| Qi H and Ratnam M | Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. | 2006 | Cancer Res. | pmid:16740727 |
| Nusinzon I and Horvath CM | Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation. | 2006 | Mol. Cell. Biol. | pmid:16581785 |
| Ibanez de Caceres I et al. | Identification of novel target genes by an epigenetic reactivation screen of renal cancer. | 2006 | Cancer Res. | pmid:16707423 |
| Kim MY et al. | Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. | 2006 | Mol. Endocrinol. | pmid:16497729 |
| Leng Y and Chuang DM | Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. | 2006 | J. Neurosci. | pmid:16837598 |
| Clem BF and Clark BJ | Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene. | 2006 | Mol. Endocrinol. | pmid:16109738 |
| Yao J et al. | NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. | 2006 | Pharmacol. Res. | pmid:17005413 |
| Inoue K et al. | Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. | 2006 | Arterioscler. Thromb. Vasc. Biol. | pmid:17008592 |
| Baqir S and Smith LC | Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. | 2006 | Cloning Stem Cells | pmid:17009896 |
| Hong ZY et al. | [Mechanism of apoptosis induced by trichostatin A in leukemia Molt-4 cells analyzed by microarray]. | 2006 | Ai Zheng | pmid:16965673 |
| Banwell CM et al. | Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. | 2006 | Clin. Cancer Res. | pmid:16609009 |
| Mühlethaler-Mottet A et al. | Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. | 2006 | BMC Cancer | pmid:16930472 |
| Suzuki T et al. | Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. | 2006 | J. Med. Chem. | pmid:16884291 |
| Kim TY et al. | Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. | 2006 | Cancer Res. | pmid:16885346 |
| Kimura N et al. | Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification. | 2006 | Protist | pmid:16839811 |
| Monte M et al. | MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16847267 |
| Zaveri NT et al. | Regulation of the prepronociceptin gene and its effect on neuronal differentiation. | 2006 | Gene | pmid:16935438 |
| Osborn NK et al. | Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. | 2006 | Clin. Gastroenterol. Hepatol. | pmid:16469682 |
| Baraz L et al. | Tumor suppressor p53 regulates heparanase gene expression. | 2006 | Oncogene | pmid:16474844 |
| Gialitakis M et al. | Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. | 2006 | Nucleic Acids Res. | pmid:16452299 |
| Cecconi D et al. | Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A. | 2005 Nov-Dec | J. Proteome Res. | pmid:16335935 |
| Garcia BA et al. | Resetting the epigenetic histone code in the MRL-lpr/lpr mouse model of lupus by histone deacetylase inhibition. | 2005 Nov-Dec | J. Proteome Res. | pmid:16335948 |
| Huang W et al. | Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex. | 2005 | J. Biol. Chem. | pmid:15647279 |
| Choi JH et al. | Trichostatin A attenuates airway inflammation in mouse asthma model. | 2005 | Clin. Exp. Allergy | pmid:15649272 |
| Varshochi R et al. | ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line. | 2005 | J. Biol. Chem. | pmid:15557281 |
| Goeman F et al. | Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras. | 2005 | Mol. Cell. Biol. | pmid:15601862 |
| Tai HH et al. | Dynamic histone acetylation of late embryonic genes during seed germination. | 2005 | Plant Mol. Biol. | pmid:16307366 |
| Noh EJ et al. | Methyl CpG-binding domain protein 3 mediates cancer-selective cytotoxicity by histone deacetylase inhibitors via differential transcriptional reprogramming in lung cancer cells. | 2005 | Cancer Res. | pmid:16357148 |
| Wetzel M et al. | Effect of trichostatin A, a histone deacetylase inhibitor, on glioma proliferation in vitro by inducing cell cycle arrest and apoptosis. | 2005 | J. Neurosurg. | pmid:16383255 |
| Lee JH et al. | Interactions with p300 enhance transcriptional activation by the PDZ-domain coactivator Bridge-1. | 2005 | J. Endocrinol. | pmid:16293776 |
| Hazzalin CA and Mahadevan LC | Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: analysis at c-fos and c-jun. | 2005 | PLoS Biol. | pmid:16262446 |
| Hohl M and Thiel G | Cell type-specific regulation of RE-1 silencing transcription factor (REST) target genes. | 2005 | Eur. J. Neurosci. | pmid:16262660 |
| Bernes S et al. | Epigenetic and classical activation of Entamoeba histolytica heat shock protein 100 (EHsp100) expression. | 2005 | FEBS Lett. | pmid:16263115 |
| Gao S et al. | CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines. | 2005 | Thromb. Haemost. | pmid:16268485 |
| Li XX et al. | Function of c-Fos-like and c-Jun-like proteins on trichostatin A-induced G2/M arrest in Physarum polycephalum. | 2005 | Acta Biochim. Biophys. Sin. (Shanghai) | pmid:16270156 |
| Francia G et al. | Down-regulation of DNA mismatch repair proteins in human and murine tumor spheroids: implications for multicellular resistance to alkylating agents. | 2005 | Mol. Cancer Ther. | pmid:16227397 |
| Chou SD et al. | Histone acetylation regulates the cell type specific CIITA promoters, MHC class II expression and antigen presentation in tumor cells. | 2005 | Int. Immunol. | pmid:16210330 |
| Osada H et al. | Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines. | 2005 | Mol. Carcinog. | pmid:16163707 |
| Rogier E et al. | A novel biological assay to detect the active form of TGF-beta in urine to monitor renal allograft rejection. | 2005 | Kidney Int. | pmid:16164666 |
| Di-Poï N et al. | Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins. | 2005 | J. Biol. Chem. | pmid:16166081 |
| Spengler ML et al. | Sumoylation of internally initiated Sp3 isoforms regulates transcriptional repression via a Trichostatin A-insensitive mechanism. | 2005 | Cell. Signal. | pmid:15494207 |
| Valenzuela-Fernández A et al. | Histone deacetylase 6 regulates human immunodeficiency virus type 1 infection. | 2005 | Mol. Biol. Cell | pmid:16148047 |
| Davis FJ et al. | Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15388503 |
| Korutla L et al. | The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures. | 2005 | J. Neurochem. | pmid:16033423 |
| Shindo N et al. | The ESC-E(Z) complex participates in the hedgehog signaling pathway. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15652519 |
| Kemp MG et al. | The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells. | 2005 | Nucleic Acids Res. | pmid:15653633 |
| Huang H et al. | MEIS C termini harbor transcriptional activation domains that respond to cell signaling. | 2005 | J. Biol. Chem. | pmid:15654074 |
| Danam RP et al. | Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins. | 2005 | Mol. Cancer Ther. | pmid:15657354 |
| Li Y et al. | Histone deacetylation is required for progression through mitosis in tobacco cells. | 2005 | Plant J. | pmid:15659094 |
| Zhao Y et al. | Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors. | 2005 | J. Exp. Biol. | pmid:15695762 |
| Hooven LA et al. | Effects of suberoylanilide hydroxamic acid and trichostatin A on induction of cytochrome P450 enzymes and benzo[a]pyrene DNA adduct formation in human cells. | 2005 | Bioorg. Med. Chem. Lett. | pmid:15713371 |
| Chen B et al. | Chemistry and biology of mercaptoacetamides as novel histone deacetylase inhibitors. | 2005 | Bioorg. Med. Chem. Lett. | pmid:15713393 |
| Touma SE et al. | Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model. | 2005 | Clin. Cancer Res. | pmid:15867260 |
| Fish JE et al. | The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code. | 2005 | J. Biol. Chem. | pmid:15870070 |
| Dyson MH et al. | MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2. | 2005 | J. Cell. Sci. | pmid:15870105 |
| Reid G et al. | Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A. | 2005 | Oncogene | pmid:15870696 |
| Kim MS et al. | Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA). | 2005 | Exp. Cell Res. | pmid:15878336 |
| Rosenqvist N et al. | Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain. | 2005 | Cell Transplant | pmid:15881422 |
| Gonçalves J et al. | Modulation of translation factor's gene expression by histone deacetylase inhibitors in breast cancer cells. | 2005 | Clin. Chem. Lab. Med. | pmid:15843208 |
| Gunin AG et al. | Effects of histone deacetylase inhibitors on estradiol-induced proliferation and hyperplasia formation in the mouse uterus. | 2005 | J. Endocrinol. | pmid:15930180 |
| Komata T et al. | Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells. | 2005 | Int. J. Oncol. | pmid:15809727 |
| Wittich S et al. | Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines. | 2005 | Anticancer Drugs | pmid:15930892 |
| Kaneda R et al. | Genome-wide screening for target regions of histone deacetylases in cardiomyocytes. | 2005 | Circ. Res. | pmid:16002748 |
| Kusy S et al. | Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene. | 2005 | Biochim. Biophys. Acta | pmid:16005989 |
| Rho JH et al. | Doxorubicin induces apoptosis with profile of large-scale DNA fragmentation and without DNA ladder in anaplastic thyroid carcinoma cells via histone hyperacetylation. | 2005 | Int. J. Oncol. | pmid:16010429 |
| Choi YH | Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells. | 2005 | Int. J. Oncol. | pmid:16010430 |
| Taddei A et al. | The effects of histone deacetylase inhibitors on heterochromatin: implications for anticancer therapy? | 2005 | EMBO Rep. | pmid:15940285 |
| Gray SG et al. | Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein. | 2005 | J. Biol. Chem. | pmid:15927959 |
| Schroeder TM and Westendorf JJ | Histone deacetylase inhibitors promote osteoblast maturation. | 2005 | J. Bone Miner. Res. | pmid:16294278 |
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| Fishel ML et al. | Effect of cell cycle inhibition on Cisplatin-induced cytotoxicity. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15304523 |
| Xiong Y et al. | Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells. | 2005 | Cancer Res. | pmid:15805266 |
| Kumakura S et al. | Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells. | 2005 | Cancer Res. | pmid:15805278 |
| Zhao W et al. | The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island. | 2005 | J. Biochem. | pmid:15809347 |
| Subramanian C et al. | Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15778293 |
| Lu ZP et al. | Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15781251 |
| Nishigaki M et al. | Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays. | 2005 | Cancer Res. | pmid:15781621 |
| Bai J et al. | Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro. | 2005 | Cancer Res. | pmid:15781649 |
| Rahmani M et al. | Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species. | 2005 | Cancer Res. | pmid:15781658 |
| Frescas D et al. | Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. | 2005 | J. Biol. Chem. | pmid:15788402 |
| Ezzat S et al. | The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility. | 2005 | Mol. Endocrinol. | pmid:15618287 |