Wang LG et al. |
Androgen receptor level controlled by a suppressor complex lost in an androgen-independent prostate cancer cell line. |
2004 |
Oncogene |
pmid:15156193
|
Romanski A et al. |
Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia. |
2004 |
Haematologica |
pmid:15075075
|
Ahmed S et al. |
A novel protein with similarities to Rb binding protein 2 compensates for loss of Chk1 function and affects histone modification in fission yeast. |
2004 |
Mol. Cell. Biol. |
pmid:15082762
|
Amor DJ et al. |
Human centromere repositioning "in progress". |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15084747
|
Tani M et al. |
Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cells. |
2004 |
Genes Chromosomes Cancer |
pmid:15101048
|
Lasa A et al. |
MEIS 1 expression is downregulated through promoter hypermethylation in AML1-ETO acute myeloid leukemias. |
2004 |
Leukemia |
pmid:15103390
|
Yokota T et al. |
Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. |
2004 |
Oncogene |
pmid:15107822
|
McGarry LC et al. |
Invasion of v-Fos(FBR)-transformed cells is dependent upon histone deacetylase activity and suppression of histone deacetylase regulated genes. |
2004 |
Oncogene |
pmid:15107823
|
Chen YX et al. |
[Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines]. |
2004 |
Zhonghua Yi Xue Za Zhi |
pmid:15059516
|
Hildmann C et al. |
A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases. |
2004 |
J. Bacteriol. |
pmid:15060035
|
Vorontsova M et al. |
Effect of 5-azacytidine and trichostatin A on somatic centromere association in wheat. |
2004 |
Genome |
pmid:15060593
|
Tong X et al. |
Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15063780
|
Kurtev V et al. |
Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases. |
2004 |
J. Biol. Chem. |
pmid:15140878
|
Kim YH et al. |
Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells. |
2004 |
Carcinogenesis |
pmid:15142888
|
Klampfer L et al. |
Requirement of histone deacetylase activity for signaling by STAT1. |
2004 |
J. Biol. Chem. |
pmid:15123634
|
Margueron R et al. |
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens. |
2004 |
J. Mol. Endocrinol. |
pmid:15072561
|
Reifenberger J et al. |
Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas. |
2004 |
Int. J. Cancer |
pmid:14961576
|
Sugimoto S et al. |
Expression and regulation of tumor suppressor gene maspin in human bladder cancer. |
2004 |
Cancer Lett. |
pmid:14732229
|
Vaisburg A et al. |
(2-amino-phenyl)-amides of omega-substituted alkanoic acids as new histone deacetylase inhibitors. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:14684344
|
Nojima H et al. |
Increase in DNA methylation downregulates conceptus interferon-tau gene expression. |
2004 |
Mol. Reprod. Dev. |
pmid:14991730
|
Leu TH et al. |
Participation of p97Eps8 in Src-mediated transformation. |
2004 |
J. Biol. Chem. |
pmid:14699156
|
Chua YL et al. |
Microarray analysis of chromatin-immunoprecipitated DNA identifies specific regions of tobacco genes associated with acetylated histones. |
2004 |
Plant J. |
pmid:14996214
|
Khan AN et al. |
An epigenetically altered tumor cell vaccine. |
2004 |
Cancer Immunol. Immunother. |
pmid:14997346
|
Pagans S et al. |
Repression by TTK69 of GAGA-mediated activation occurs in the absence of TTK69 binding to DNA and solely requires the contribution of the POZ/BTB domain of TTK69. |
2004 |
J. Biol. Chem. |
pmid:14701830
|
Ragno R et al. |
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies. |
2004 |
J. Med. Chem. |
pmid:14998325
|
Hwang CK et al. |
Transcriptional regulation of mouse mu opioid receptor gene by PU.1. |
2004 |
J. Biol. Chem. |
pmid:14998994
|
Brush MH et al. |
Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases. |
2004 |
J. Biol. Chem. |
pmid:14670976
|
Gray SG et al. |
Microarray profiling of the effects of histone deacetylase inhibitors on gene expression in cancer cell lines. |
2004 |
Int. J. Oncol. |
pmid:15010814
|
Lee JH et al. |
Histone deacetylase activity is required for embryonic stem cell differentiation. |
2004 |
Genesis |
pmid:14755802
|
Lemonde S et al. |
Cell type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene. |
2004 |
J. Neurochem. |
pmid:14756806
|
Aapola U et al. |
Epigenetic modifications affect Dnmt3L expression. |
2004 |
Biochem. J. |
pmid:15015937
|
Hattori N et al. |
Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. |
2004 |
J. Biol. Chem. |
pmid:14761969
|
Burton GR et al. |
Microarray analysis of differentiation-specific gene expression during 3T3-L1 adipogenesis. |
2004 |
Gene |
pmid:15033539
|
David GL et al. |
MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine. |
2004 |
Cancer Biol. Ther. |
pmid:15034303
|
Liu X et al. |
Nuclear factor Y regulation and promoter transactivation of human ribonucleotide reductase subunit M2 gene in a Gemcitabine resistant KB clone. |
2004 |
Biochem. Pharmacol. |
pmid:15041467
|
Elaut G et al. |
Rat hepatocyte suspensions as a suitable in vitro model for studying the biotransformation of histone deacetylase inhibitors. |
2004 |
Altern Lab Anim |
pmid:23577441
|
Christian M et al. |
Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140. |
2004 |
J. Biol. Chem. |
pmid:14736873
|
Mai A et al. |
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity. |
2004 |
J. Med. Chem. |
pmid:14971890
|
Nishikawa J et al. |
Upregulation of LMP1 expression by histone deacetylase inhibitors in an EBV carrying NPC cell line. |
2004 |
Virus Genes |
pmid:14739656
|
Milhem M et al. |
Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A. |
2004 |
Blood |
pmid:14976039
|
Agostinho M et al. |
Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis. |
2004 |
Mol. Biol. Cell |
pmid:14978217
|
Sakata R et al. |
Trichostatin A activates the osteopontin gene promoter through AP1 site. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14985105
|
Knobbe CB et al. |
Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas. |
2004 |
J. Natl. Cancer Inst. |
pmid:15026474
|
Chung YL et al. |
Antitumor histone deacetylase inhibitors suppress cutaneous radiation syndrome: Implications for increasing therapeutic gain in cancer radiotherapy. |
2004 |
Mol. Cancer Ther. |
pmid:15026552
|
Steiner E et al. |
SP-transcription factors are involved in basal MVP promoter activity and its stimulation by HDAC inhibitors. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15047174
|
Cao H et al. |
Induction of human gamma globin gene expression by histone deacetylase inhibitors. |
2004 |
Blood |
pmid:12920038
|
Sarg B et al. |
Histone H4 hyperacetylation precludes histone H4 lysine 20 trimethylation. |
2004 |
J. Biol. Chem. |
pmid:15456746
|
Nan X et al. |
Potent stimulation of gene expression by histone deacetylase inhibitors on transiently transfected DNA. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15465025
|
Lee HS et al. |
Gene expression analysis in human gastric cancer cell line treated with trichostatin A and S-adenosyl-L-homocysteine using cDNA microarray. |
2004 |
Biol. Pharm. Bull. |
pmid:15467184
|
Sangster-Guity N et al. |
Molecular profiling of embryonal carcinoma cells following retinoic acid or histone deacetylase inhibitor treatment. |
2004 |
Cancer Biol. Ther. |
pmid:15467438
|
Alcendor RR et al. |
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. |
2004 |
Circ. Res. |
pmid:15486319
|
Gius D et al. |
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. |
2004 |
Cancer Cell |
pmid:15488759
|
Emmans VC et al. |
Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression. |
2004 |
Biochem. Soc. Trans. |
pmid:15494029
|
Fan X et al. |
Regulation of RANKL promoter activity is associated with histone remodeling in murine bone stromal cells. |
2004 |
J. Cell. Biochem. |
pmid:15389882
|
Keen JC et al. |
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells. |
2004 |
Cancer Biol. Ther. |
pmid:15662126
|
Ding W |
[A histone deacetylase inhibitor and tumor suppressing gene p53 induction synergistically induce apoptosis of cancer cells]. |
2004 |
Hokkaido Igaku Zasshi |
pmid:15675303
|
Yamashita Y et al. |
cDNA microarray analysis in hepatocyte differentiation in Huh 7 cells. |
2004 |
Cell Transplant |
pmid:15690981
|
GarcÃa I et al. |
Chromatin rearrangements in the prnD-prnB bidirectional promoter: dependence on transcription factors. |
2004 |
Eukaryotic Cell |
pmid:14871945
|
Takai N et al. |
Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells. |
2004 |
Clin. Cancer Res. |
pmid:14871994
|
Zhang Y et al. |
Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors. |
2004 |
Radiat. Res. |
pmid:15161353
|
Glenn MP et al. |
Antiproliferative and phenotype-transforming antitumor agents derived from cysteine. |
2004 |
J. Med. Chem. |
pmid:15163181
|
Ronai D et al. |
The epigenetic stability of the locus control region-deficient IgH locus in mouse hybridoma cells is a clonally varying, heritable feature. |
2004 |
Genetics |
pmid:15166165
|
Zhang X et al. |
Activation of the growth-differentiation factor 11 gene by the histone deacetylase (HDAC) inhibitor trichostatin A and repression by HDAC3. |
2004 |
Mol. Cell. Biol. |
pmid:15169878
|
Ishiguro K and Sartorelli AC |
Activation of transiently transfected reporter genes in 3T3 Swiss cells by the inducers of differentiation/apoptosis--dimethylsulfoxide, hexamethylene bisacetamide and trichostatin A. |
2004 |
Eur. J. Biochem. |
pmid:15182353
|
Brieger A et al. |
In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors. |
2004 |
Biochem. Pharmacol. |
pmid:15183120
|
Shim JS et al. |
Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells. |
2004 |
Oncogene |
pmid:14661058
|
Chaturvedi V et al. |
Resistance to UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53. |
2004 |
J. Cell. Physiol. |
pmid:14584049
|
Laeng P et al. |
The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells. |
2004 |
J. Neurochem. |
pmid:15379904
|
Kim MK and Carroll WL |
Autoregulation of the N-myc gene is operative in neuroblastoma and involves histone deacetylase 2. |
2004 |
Cancer |
pmid:15382088
|
Tang XX et al. |
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma. |
2004 |
Clin. Cancer Res. |
pmid:15355914
|
Yokota T et al. |
Trichostatin A activates p18INK4c gene: differential activation and cooperation with p19INK4d gene. |
2004 |
FEBS Lett. |
pmid:15358560
|
Boehrer S et al. |
In the erythroleukemic cell line HEL Prostate-apoptosis-response-gene-4 (par-4) fails to down-regulate Bcl-2 and to promote apoptosis. |
2004 |
Leuk. Lymphoma |
pmid:15359646
|
Vaghefi H and Neet KE |
Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation. |
2004 |
Oncogene |
pmid:15361854
|
Moore PS et al. |
Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cells. |
2004 |
Biochim. Biophys. Acta |
pmid:15363630
|
Chiba T et al. |
Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells. |
2004 |
J. Hepatol. |
pmid:15336447
|
Liu CJ et al. |
Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. |
2004 |
J. Biol. Chem. |
pmid:15337766
|
Cosio BG et al. |
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. |
2004 |
J. Exp. Med. |
pmid:15337792
|
Jansen MS et al. |
Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition. |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15103026
|
Kang J et al. |
Synergistic killing of human leukemia cells by antioxidants and trichostatin A. |
2004 |
Cancer Chemother. Pharmacol. |
pmid:15248029
|
Jin B and Ryu DY |
Regulation of CYP1A2 by histone deacetylase inhibitors in mouse hepatocytes. |
2004 |
J. Biochem. Mol. Toxicol. |
pmid:15252868
|
Gilchrist S et al. |
Nuclear organization of centromeric domains is not perturbed by inhibition of histone deacetylases. |
2004 |
Chromosome Res. |
pmid:15254368
|
Aggarwal BD and Calvi BR |
Chromatin regulates origin activity in Drosophila follicle cells. |
2004 |
Nature |
pmid:15254542
|
Sanderson L et al. |
Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice. |
2004 |
Drug Metab. Dispos. |
pmid:15269190
|
Levenson JM et al. |
Regulation of histone acetylation during memory formation in the hippocampus. |
2004 |
J. Biol. Chem. |
pmid:15273246
|
Li X et al. |
Regulation of histone acetylation and apoptosis by trichostatin in HL-60 cells. |
2004 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:15791844
|
Liu C and Xu D |
Inhibition of histone deacetylases. |
2004 |
Methods Mol. Biol. |
pmid:15273406
|
Garfinkel MD et al. |
Multigenerational selection and detection of altered histone acetylation and methylation patterns: toward a quantitative epigenetics in Drosophila. |
2004 |
Methods Mol. Biol. |
pmid:15273410
|
Vanhaecke T et al. |
Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures. |
2004 |
Biochem. Pharmacol. |
pmid:15276083
|
ChuÄkin IA et al. |
[Transcription of c-fos gene and DNA binding activity of transcription factor AP-1 increase upon differentiation of mouse F9 teratocarcinoma cells]. |
2004 |
Tsitologiia |
pmid:15747838
|
Korzus E et al. |
CBP histone acetyltransferase activity is a critical component of memory consolidation. |
2004 |
Neuron |
pmid:15207240
|
Ishihara K et al. |
Possible mechanism of action of the histone deacetylase inhibitors for the induction of differentiation of HL-60 clone 15 cells into eosinophils. |
2004 |
Br. J. Pharmacol. |
pmid:15210580
|
Marengo E et al. |
Identification of the regulatory proteins in human pancreatic cancers treated with Trichostatin A by 2D-PAGE maps and multivariate statistical analysis. |
2004 |
Anal Bioanal Chem |
pmid:15257427
|
Schauber J et al. |
Histone-deacetylase inhibitors induce the cathelicidin LL-37 in gastrointestinal cells. |
2004 |
Mol. Immunol. |
pmid:15261456
|
De La Fuente R et al. |
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. |
2004 |
Dev. Biol. |
pmid:15242786
|
Fang JY et al. |
Epigenetic modification regulates both expression of tumor-associated genes and cell cycle progressing in human colon cancer cell lines: Colo-320 and SW1116. |
2004 |
Cell Res. |
pmid:15225415
|
Banwell CM et al. |
Targeting 1alpha,25-dihydroxyvitamin D3 antiproliferative insensitivity in breast cancer cells by co-treatment with histone deacetylation inhibitors. |
2004 |
J. Steroid Biochem. Mol. Biol. |
pmid:15225779
|
Mao DY et al. |
Promoter-binding and repression of PDGFRB by c-Myc are separable activities. |
2004 |
Nucleic Acids Res. |
pmid:15226411
|
Naruse Y et al. |
Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation. |
2004 |
Mol. Cell. Biol. |
pmid:15226430
|
Alao JP et al. |
Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines. |
2004 |
Clin. Cancer Res. |
pmid:15585645
|
Swank RA et al. |
The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced gamma globin expression in somatic cell hybrids and induces gamma gene expression in adult BFUe cultures. |
2003 May-Jun |
Blood Cells Mol. Dis. |
pmid:12737942
|