Meng CF et al. |
Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells. |
2010 |
Cancer Invest. |
pmid:19857042
|
Fang Y et al. |
Synergistic efficacy in human ovarian cancer cells by histone deacetylase inhibitor TSA and proteasome inhibitor PS-341. |
2011 |
Cancer Invest. |
pmid:21345073
|
Khan AN et al. |
An epigenetically altered tumor cell vaccine. |
2004 |
Cancer Immunol. Immunother. |
pmid:14997346
|
Khan AN et al. |
Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells. |
2008 |
Cancer Immunol. Immunother. |
pmid:18046553
|
Tiper IV and Webb TJ |
Histone deacetylase inhibitors enhance CD1d-dependent NKT cell responses to lymphoma. |
2016 |
Cancer Immunol. Immunother. |
pmid:27614429
|
Neumann F et al. |
EBV-transformed lymphoblastoid cell lines as vaccines against cancer testis antigen-positive tumors. |
2013 |
Cancer Immunol. Immunother. |
pmid:23619976
|
Mazzio EA and Soliman KFA |
Whole-transcriptomic Profile of SK-MEL-3 Melanoma Cells Treated with the Histone Deacetylase Inhibitor: Trichostatin A. |
|
Cancer Genomics Proteomics |
pmid:30194076
|
Mazzio EA and Soliman KF |
HTP Nutraceutical Screening for Histone Deacetylase Inhibitors and Effects of HDACis on Tumor-suppressing miRNAs by Trichostatin A and Grapeseed (Vitis vinifera) in HeLa cells. |
2017 |
Cancer Genomics Proteomics |
pmid:28031235
|
Shin S et al. |
Trichostatin A Sensitizes Hepatocellular Carcinoma Cells to Enhanced NK Cell-mediated Killing by Regulating Immune-related Genes. |
|
Cancer Genomics Proteomics |
pmid:28871002
|
Zhou X et al. |
The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma. |
2007 |
Cancer Genet. Cytogenet. |
pmid:17693185
|
Wunder T et al. |
Expression of the coxsackie adenovirus receptor in neuroendocrine lung cancers and its implications for oncolytic adenoviral infection. |
2013 |
Cancer Gene Ther. |
pmid:23196273
|
El-Zawahry A et al. |
In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL. |
2006 |
Cancer Gene Ther. |
pmid:16167063
|
Katsura T et al. |
The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells. |
2009 |
Cancer Gene Ther. |
pmid:18949013
|
Yoshida M et al. |
Histone deacetylase as a new target for cancer chemotherapy. |
2001 |
Cancer Chemother. Pharmacol. |
pmid:11587361
|
Bovenzi V and Momparler RL |
Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. |
2001 |
Cancer Chemother. Pharmacol. |
pmid:11488527
|
Whang YM et al. |
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells. |
2005 |
Cancer Chemother. Pharmacol. |
pmid:15959780
|
Kang J et al. |
Synergistic killing of human leukemia cells by antioxidants and trichostatin A. |
2004 |
Cancer Chemother. Pharmacol. |
pmid:15248029
|
Fandy TE and Srivastava RK |
Trichostatin A sensitizes TRAIL-resistant myeloma cells by downregulation of the antiapoptotic Bcl-2 proteins. |
2006 |
Cancer Chemother. Pharmacol. |
pmid:16435155
|
Yamashita K et al. |
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. |
2002 |
Cancer Cell |
pmid:12498717
|
Gius D et al. |
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. |
2004 |
Cancer Cell |
pmid:15488759
|
Maecker HL et al. |
Epigenetic changes in tumor Fas levels determine immune escape and response to therapy. |
2002 |
Cancer Cell |
pmid:12204534
|
Jiang X et al. |
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. |
2008 |
Cancer Cell |
pmid:18538736
|
Brugarolas JB et al. |
TSC2 regulates VEGF through mTOR-dependent and -independent pathways. |
2003 |
Cancer Cell |
pmid:12957289
|
Tuncel M et al. |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. |
2007 |
Cancer Biother. Radiopharm. |
pmid:17600477
|
Tuncel M et al. |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. |
2007 |
Cancer Biother. Radiopharm. |
pmid:17679169
|
Cao QF et al. |
TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells. |
2015 |
Cancer Biother. Radiopharm. |
pmid:25760728
|
Tang X et al. |
Protocadherin 10 is frequently downregulated by promoter methylation and functions as a tumor suppressor gene in non-small cell lung cancer. |
2012-2013 |
Cancer Biomark |
pmid:23321465
|
Trtková K et al. |
Formation of AR-SMRT binding in prostate cancer cells treated with natural histone deacetylase inhibitor. |
2010 |
Cancer Biomark |
pmid:21178266
|
El-Awady RA et al. |
Epigenetics and miRNA as predictive markers and targets for lung cancer chemotherapy. |
2015 |
Cancer Biol. Ther. |
pmid:25962089
|
Lo PK et al. |
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. |
2006 |
Cancer Biol. Ther. |
pmid:16410723
|
Taghiyev AF et al. |
TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome. |
2006 |
Cancer Biol. Ther. |
pmid:17110788
|
David GL et al. |
MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine. |
2004 |
Cancer Biol. Ther. |
pmid:15034303
|
Sangster-Guity N et al. |
Molecular profiling of embryonal carcinoma cells following retinoic acid or histone deacetylase inhibitor treatment. |
2004 |
Cancer Biol. Ther. |
pmid:15467438
|
Song K et al. |
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer. |
2011 |
Cancer Biol. Ther. |
pmid:21709440
|
Karagiannis TC et al. |
The histone deacetylase inhibitor, Trichostatin A, enhances radiation sensitivity and accumulation of gammaH2A.X. |
2005 |
Cancer Biol. Ther. |
pmid:16082178
|
Mazzarelli P et al. |
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation? |
2007 |
Cancer Biol. Ther. |
pmid:18253084
|
Keen JC et al. |
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells. |
2004 |
Cancer Biol. Ther. |
pmid:15662126
|
Ranganathan P and Rangnekar VM |
Exploiting the TSA connections to overcome apoptosis-resistance. |
2005 |
Cancer Biol. Ther. |
pmid:15908800
|
Taghiyev AF et al. |
Trichostatin A (TSA) sensitizes the human prostatic cancer cell line DU145 to death receptor ligands treatment. |
2005 |
Cancer Biol. Ther. |
pmid:15846101
|
Chatterjee N et al. |
Histone deacetylase inhibitors modulate miRNA and mRNA expression, block metaphase, and induce apoptosis in inflammatory breast cancer cells. |
2013 |
Cancer Biol. Ther. |
pmid:23792638
|
Anantharaju PG et al. |
Naturally occurring benzoic acid derivatives retard cancer cell growth by inhibiting histone deacetylases (HDAC). |
2017 |
Cancer Biol. Ther. |
pmid:28506198
|
Chakravarty G et al. |
Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment. |
2011 |
Cancer Biol. Ther. |
pmid:21084857
|
Honda H et al. |
Regulation of the CLDN3 gene in ovarian cancer cells. |
2007 |
Cancer Biol. Ther. |
pmid:17986852
|
Zhang XH et al. |
Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer. |
2008 |
Cancer Biol. Ther. |
pmid:18708766
|
Zhang F et al. |
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. |
2009 |
Cancer Biol. Ther. |
pmid:19270532
|
Dowling M et al. |
Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents. |
2005 |
Cancer Biol. Ther. |
pmid:15753652
|
Guo W et al. |
Aberrant methylation and decreased expression of the TGF-β/Smad target gene FBXO32 in esophageal squamous cell carcinoma. |
2014 |
Cancer |
pmid:24798237
|
Pan L et al. |
Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression. |
2007 |
Cancer |
pmid:17330857
|
Tan L et al. |
Trichostatin A restores Apaf-1 function in chemoresistant ovarian cancer cells. |
2011 |
Cancer |
pmid:20925046
|
Chen MY et al. |
Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy. |
2011 |
Cancer |
pmid:21491416
|
Kim MK and Carroll WL |
Autoregulation of the N-myc gene is operative in neuroblastoma and involves histone deacetylase 2. |
2004 |
Cancer |
pmid:15382088
|
Xu J et al. |
CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors. |
2010 |
Breast Cancer Res. Treat. |
pmid:19466541
|
Motevalli A et al. |
The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines. |
2014 |
Breast Cancer Res. Treat. |
pmid:24807106
|
Domingo-Domènech J et al. |
Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. |
2008 |
Breast Cancer Res. Treat. |
pmid:18064564
|
Huang KT et al. |
Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer. |
2011 |
Breast Cancer Res. Treat. |
pmid:21755341
|
Pryzbylkowski P et al. |
Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. |
2008 |
Breast Cancer Res. Treat. |
pmid:17891453
|
Auer D et al. |
Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
pmid:18618240
|
Kim SH et al. |
Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein. |
2010 |
Breast Cancer Res. |
pmid:20388208
|
Zych J et al. |
The epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A influence adipocyte differentiation in human mesenchymal stem cells. |
2013 |
Braz. J. Med. Biol. Res. |
pmid:23797495
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. |
2002 |
Brain Tumor Pathol |
pmid:12622137
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. |
2001 |
Brain Tumor Pathol |
pmid:11908866
|
Sakharkar AJ et al. |
A role for histone acetylation mechanisms in adolescent alcohol exposure-induced deficits in hippocampal brain-derived neurotrophic factor expression and neurogenesis markers in adulthood. |
2016 |
Brain Struct Funct |
pmid:26941165
|
Sharifulina SA et al. |
Epigenetic regulation of death of crayfish glial cells but not neurons induced by photodynamic impact. |
2014 |
Brain Res. Bull. |
pmid:24502940
|
Niu F et al. |
Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-kappaB. |
2009 |
Brain Res. Bull. |
pmid:19103266
|
Lin YC et al. |
Effects of trichostatin A on neuronal mu-opioid receptor gene expression. |
2008 |
Brain Res. |
pmid:18950606
|
Suzuki-Mizushima Y et al. |
Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. |
2002 |
Brain Res. |
pmid:12270499
|
Sano M and Kitajima S |
Inhibition of the nerve growth factor-induced outgrowth of neurites by trichostatin A requires protein synthesis de novo in PC12D cells. |
1996 |
Brain Res. |
pmid:9117395
|
Wei L et al. |
Microinjection of histone deacetylase inhibitor into the ventrolateral orbital cortex potentiates morphine induced behavioral sensitization. |
2016 |
Brain Res. |
pmid:27312092
|
Hou X et al. |
HDAC inhibitor TSA ameliorates mechanical hypersensitivity and potentiates analgesic effect of morphine in a rat model of bone cancer pain by restoring μ-opioid receptor in spinal cord. |
2017 |
Brain Res. |
pmid:28559159
|
Li KK et al. |
MiR-383 is downregulated in medulloblastoma and targets peroxiredoxin 3 (PRDX3). |
2013 |
Brain Pathol. |
pmid:23227829
|
Li KK et al. |
MIR-137 suppresses growth and invasion, is downregulated in oligodendroglial tumors and targets CSE1L. |
2013 |
Brain Pathol. |
pmid:23252729
|
Gaub P et al. |
The histone acetyltransferase p300 promotes intrinsic axonal regeneration. |
2011 |
Brain |
pmid:21705428
|
Xin C et al. |
FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism. |
2007 |
Br. J. Pharmacol. |
pmid:17325654
|
Matsushita Y et al. |
HDAC inhibitors restore C-fibre sensitivity in experimental neuropathic pain model. |
2013 |
Br. J. Pharmacol. |
pmid:24032674
|
Ishihara K et al. |
Possible mechanism of action of the histone deacetylase inhibitors for the induction of differentiation of HL-60 clone 15 cells into eosinophils. |
2004 |
Br. J. Pharmacol. |
pmid:15210580
|
Chen CZ et al. |
The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well. |
2009 |
Br. J. Pharmacol. |
pmid:19785660
|
Hoshimoto A et al. |
Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A. |
2002 |
Br. J. Pharmacol. |
pmid:12010777
|
Kiefer J et al. |
Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. |
2006 |
Br. J. Nutr. |
pmid:17092367
|
Amin HM et al. |
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). |
2001 |
Br. J. Haematol. |
pmid:11703323
|
Vinatzer U et al. |
The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase. |
2001 |
Br. J. Haematol. |
pmid:11552981
|
Welch MD et al. |
Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemia. |
2013 |
Br. J. Haematol. |
pmid:23772794
|
Kitamura K et al. |
Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all-trans retinoic acid. |
2000 |
Br. J. Haematol. |
pmid:10792271
|
Yamamura K et al. |
Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. |
2006 |
Br. J. Haematol. |
pmid:16939493
|
Li X et al. |
Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. |
2010 |
Br. J. Haematol. |
pmid:19807731
|
Yasukawa K et al. |
Histone deacetylase inhibitors preferentially augment transient transgene expression in human dermal fibroblasts. |
2007 |
Br. J. Dermatol. |
pmid:17711521
|
Truong M et al. |
Even-skipped homeobox 1 is frequently hypermethylated in prostate cancer and predicts PSA recurrence. |
2012 |
Br. J. Cancer |
pmid:22596233
|
Meng F et al. |
Anticancer efficacy of cisplatin and trichostatin A or 5-aza-2'-deoxycytidine on ovarian cancer. |
2013 |
Br. J. Cancer |
pmid:23370212
|
Zaman MS et al. |
The functional significance of microRNA-145 in prostate cancer. |
2010 |
Br. J. Cancer |
pmid:20588276
|
Ridolfi E et al. |
Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs. |
2008 |
Br. J. Cancer |
pmid:18941460
|
El-Khoury V et al. |
The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model. |
2007 |
Br. J. Cancer |
pmid:17667922
|
Yamada N et al. |
Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. |
2009 |
Br. J. Cancer |
pmid:19127263
|
Chang J et al. |
Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide. |
2012 |
Br. J. Cancer |
pmid:22158273
|
Frame FM et al. |
HDAC inhibitor confers radiosensitivity to prostate stem-like cells. |
2013 |
Br. J. Cancer |
pmid:24220693
|
Moreaux J et al. |
Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors. |
2013 |
Br. J. Cancer |
pmid:23868005
|
Carén H et al. |
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours. |
2007 |
Br. J. Cancer |
pmid:17940511
|
Dote H et al. |
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour. |
2005 |
Br. J. Cancer |
pmid:15770214
|
Huynh NC et al. |
Histone deacetylase inhibition enhances in-vivo bone regeneration induced by human periodontal ligament cells. |
2017 |
Bone |
pmid:27871909
|
Bieluszewski T et al. |
AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex. |
2015 |
BMC Plant Biol. |
pmid:25849764
|
Yang F et al. |
Trichostatin A and 5-azacytidine both cause an increase in global histone H4 acetylation and a decrease in global DNA and H3K9 methylation during mitosis in maize. |
2010 |
BMC Plant Biol. |
pmid:20718950
|
Mercer TR et al. |
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation. |
2010 |
BMC Neurosci |
pmid:20137068
|